药学英语 标准试卷9

一、翻译（共20分,每题1分）。

1 Nonane

2 Sodium

3 Silver

4 Arginine

5 Histidine

6 Phenol

7 Acetone 8 Sodium chloride

9 Potassium carbonate 10 Chlorine

11 乙烷12 甲醇

13 溴14 汞

15 腺嘌呤16 赖氨酸

17 胞嘧啶18 乙酸乙酯

19 氢氧化钠20 碳酸钾

答案:

1 壬烷

2 钠

3 银

4 精氨酸

5 组氨酸

6 酚

7 酮8 氯化钠

9 碳酸钾10 氯

11 Ethane 12 Methanol

13 Bromine 14 Mercury

15 Adenine 16 Lysine

17 Cytosine 18 Ethyl acetate

19 Sodium hydroxide 20 Potassium carbonate

二、写出下列缩写的英文全称并翻译（共10分,每题2分）。

1 WHO:

2 SFDA:

3 IR:

4 CTO:

5 NMR:

答案: 1 W orld Health Organization 世界卫生组织

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2 State Food and Drug Administration 国家食品药品监督管理局

3 Infrared spectroscopy 红外光谱

4 Chief Technology Officer 首席技术官

5 Nuclear Magnetic Resonance Spectroscopy 核磁共振光谱

三、判断，并用×√表示（共16分,每题2分）。

1 （）There are three phases in the analysis: the fast-screening phase, the identification phase and possible quantification.

2 （）The present trend is mass screening of huge libraries containing several thousand molecules. This was made possible by the association of combinational chemistry with NMR.

3 （）Presently, as NMR, it is applied in a very general manner to synthetic as well as to natural compounds in the search for new lead compound.

4 （）Thus were produced, over millions of years, the earth itself and the chemical elements found on the earth today.

5 （）This is determined mainly by the lipid solubility of the drug, highly polar water-soluble drugs being transferred slowly whereas highly lipidsoluble, non-polar drugs are transferred rapidly across the lipid-rich membranes of cells.

6 （）Higher concentration of surfactants tends to form micelles with the drug and thus decrease the dissolution rate.

7 （）For growth regulators a bioassay is not an essential part of identification.

8 （）GMP is probably the most widespread quality system followed across the pharmaceutical industry as a whole

答案: 1 √ 2 × 3 × 4 × 5 √ 6 ×7 ×8 √

四、单选题（共14分,每题2分）。

1 Analytical chemistry provides the B and tools needed for insight into our

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material world

A choices

B methods

C improvements

D arrangements

2 The crucial property for the D was that it should be recognized and bound to the binding site of the target receptor.

A chemical messenger

B tissue

C cell

D lead compound

3 Aldehydes and ketones have C groups

A acetyl

B aldehyde

C carbonyl

D carboxyl

4 In view of the complexity of the human body, it is inevitable that pharmacokinetic formulations must be A drastically simplifying assumptions.

A based on

B depend on

C come on

D according to

5 A increase the viscosity of the drug vehicle and thereby diminish the rate of drug dissolution of suspensions.

A Suspending agents

B Lubricants

C Surfactants

D Excipients

6 With new compounds, however, it is A to confirm the identification through chemical degradation or by preparing the compound by laboratory synthesis.

A preferable

B good

C well

D better

7 Low concentrations of surfactants lower _______ and increase _______, whereas higher concentration of surfactants tends to form micelles with the drug and thus decrease _______.

A the surface tension the rate of the drug dissolution the dissolution rate

B the dissolution rate the surface tension the rate of the drug dissolution

C the rate of the drug dissolution the dissolution rate the surface tension

D the dissolution rate the rate of the drug dissolution the surface tension

答案: 1 B 2 D 3 C 4 A 5 A 6 A 7 A

五、英译汉（共20分,每题5分）。

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1 In order to design a drug product that deliver the active drug in the most bioavailable form, the pharmacist must consider (1) the type of drug product (e.g. solution, suspension, suppository); (2) the nature of the excipients in the drug products; (3) the physicochemical properties of the drug molecule.

答案：为了设计一种使活性药物最有效的药物产品，药剂师必须考虑到 1 药品的剂型（例如，溶液剂、悬浮剂、栓剂）2 药品中辅料的性质 3 药物分子的物理化学性质。

2 With new compounds, however, it is preferable to confirm the identification through chemical degradation or by preparing the compound by laboratory synthesis.

答案：然而对于新的化合物，最好是通过化学降解确认或准备通过实验室合成的化合物。

3 Lead compounds can be obtained from a variety of different sources such as the flora and fauna of the natural world, or synthetic compounds made in the laboratory. There is also the potential of designing lead compounds using computer modeling or NMR spectroscopic studies.

答案：先导化合物的来源多种多样，例如自然界中的植物动物或是实验室中的合成化合物，也可以来源于电脑模拟或核磁图谱。

4 Presently, as high-throughput screening (HTS),it is applied in a very general manner to synthetic as well as to natural compounds in the search for new lead compound.

答案：现在，高通筛选是适用于合成和天然化合物的一般方法。

5 There are three phases in the analysis: the fast-screening phase, the identification phase and possible quantification.

答案：分析的过程分三个阶段进行：快速筛选阶段，确定阶段，可能的量化阶段

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六、问答题（共20分,每题5分）。

1 What’s the aim of biochemistry?

答案：Biochemistry aim to explain biological form and function in chemical terms.

2 Drugs are administered as the form of?

答案：Capsules, tablets and pills, a volatile liquid, a solution, an aerosol, a gas, a crystalline suspension.

3 what distinction should be made between the terms selective and specific:

答案：(1) A selective reaction or test is one that can occur with other substances but exhibits a degree of preference for the substance of interest.

(2) A specific reaction or test is one that occur only with the substance of interest.

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