依达拉奉注射液联合奥扎格雷钠治疗脑血栓形成的效果分析

·内科研究·SYSTEMS MEDICINE 系统医学系统医学2016年6月第1卷第6期动脉粥样硬化从而导致血管的管腔渐渐狭窄最

终闭塞,使得脑组织血供出现问题,最终导致脑组织

坏死是脑血栓形成的病例基础,致死率极高[1-6]。而目

前药物治疗脑血栓主要是从降低血浓度着手,但发生

再次栓塞的概率依旧很高,疗效有限。本研究在常规治疗的基础上采用依达拉奉注射液联合奥扎格雷钠治疗,一方面提高脑血栓患者屏障的通透性,另一方面抑制血小板的聚集,显著减少血栓的形成,同时也减少的血栓素的产生,改善血液循环,提高了患者的供氧能力[7]。该院自2013年6月—2015年6月期间,

使用依达拉奉注射液联合奥扎格雷钠治疗脑血栓形

DOI :10.19368/https://www.360docs.net/doc/f79580845.html,ki.2096-1782.2016.06.023

依达拉奉注射液联合奥扎格雷钠治疗脑血栓形成的

效果分析

慕玉莹,孙振永,刘以举,廖业敏

广东省阳江市阳西县人民医院內二科,广东阳江529800

[摘要]目的探讨分析依达拉奉注射液联合奥扎格雷钠治疗脑血栓形成的临床疗效。方法选择该院自2013年6月—2015年6月期间收治的100例脑血栓患者,随机分为50例对照组和50例实验组,对照组采用常规治疗加依达拉奉注射液治疗,实验组在对照组患者治疗的基础上加用奥扎格雷钠,对比两组治疗前后DBP 、脑脊液压力以及神经功能缺损评分。结果经治疗后,两组患者DBP 实验组(72.3±4.3),对照组(88.3±3.1);脑脊液压力实验组(1.38±0.31),对照组(1.72±0.36);神经功能缺损评分实验组(9.5±3.2),对照组(14.9±3.8),实验组的上述指标均显著优于对照组(P <0.05)。实验组的总有效率为90%,显著高于对照组的总有效率62%(P <0.05)。结论达拉奉注射液联合奥扎格雷钠治疗脑血栓形成的临床疗效显著,值得临床推广。

[关键词]依达拉奉注射液;奥扎格雷钠;脑血栓;联合用药

[中图分类号]R743[文献标识码]A [文章编号]2096-1782(2016)06-0023-03

The Effects of Edaravone Injection Combined with Sodium Ozagrel in the Treatment of Cerebral Thrombosis

MU Yu-ying ,SUN Zhen-yong ,LIU Yi-ju ,LIAO Ye-min

The second department of medicineYangxi People's Hospital,Yangjiang City,Guangdong Province Yangjiang ,Guang -dong Province ,529800China

[Abstract]Objective To study the clinical efficacy of Edaravone Injection combined with sodium ozagrel in the treat -ment of cerebral thrombosis.Methods Choose from June 2013to June 2015of 100cases of cerebral thrombosis pa -tients,randomly divided into for 50cases of control group and 50cases in the experimental group,control group was treated with routine treatment of edaravone injection in the treatment of,the experimental group in the control of the patients in the treatment group based on the use of sodium ozagrel,compared to two groups of curative effect.Results After treatment,two groups of patients with DBP experimental group (72.3±4.3),control group (88.3±3.1);cerebrospinal fluid pressure experimental group (138±0.31),control group (1.72±0.36);neural function defect score experimental group (9.5±3.2),control group (14.9±3.8)in experimental group of above indexes were significantly better than the control group(P <0.05).In experimental group,the total effective rate was 90%,total efficiency of 62%was significantly higher than that of control group(P <0.05).Conclusion The clinical curative effect is significantly Dallas injection combined with sodium ozagrel in the treatment of cerebral thrombosis,is worthy of promotion.

[Key words]Edaravone Injection;Sodium ozagrel;Cerebral thrombosis;Drug combination

[基金项目]广东省阳江市卫生和计划生育局科技计划项目

(专题编号20140501)。[作者简介]慕玉莹(1980-),女,湖北荆州人,本科,主治医师,主要从事神经内科临床工作。23

相关文档
最新文档