医用生物可吸收止血材料的研究现状与临床应用

张少锋;洪加源

【期刊名称】《中国组织工程研究》

【年(卷),期】2012(016)021

【摘要】BACKGROUND: Now, various hemostasis materials are developed with different components and mechanisms. Due to their different characteristics, the applications are different.OBJECTIVE: To review the commonly used clinical absorbable hemostatic materials at home and abroad, and to summarize the composition, hemostatic mechanism and clinical application for guiding clinicians to use them effectively. METHODS: A computer-based search of CNKI and PubMed databases (2002-02/2011-05) were performed for articles related to hemostatic materials using the key words of "biological material, hemostatic material, bioresorbable material, hemostatic effect, hemostatic mechanism" in Chinese and English, respectively. Literatures on application of biomedical absorbable hemostatic materials were adopted, and others about duplicated study and contents inconsistent with the research purpose were excluded. RESULTS AND CONCLUSION: Currently, fibrin glue, cellu lose, xycellulose, α-cyanoacrylate tissue glue, chitosan and so on are adsorbable hemostasis materials in clinic. The hemostatic reason of chitosan is that the chitosan has some quantitative electric charge, which can directly occur cross linking reaction with the