药学英语 标准试卷6

一、翻译（共20分,每题1分）。

1 戊烷

2 腺苷酸

3 氯

4 碘

5 脯氨酸

6 色氨酸

7 酮8 酰胺

9 CaCO310 氯化钠

11 Cyclohexane 12 Decane

13 Butanol 14 Sodium

15 Tyrosine 16 Ethyl acetate

17 Mercury 18 Phenol

19 Potassium carbonate 20 Cysteine

答案： 1 Pentane 2 Adenylic acid 3 Chlorine 4 Iodine

5 Proline

6 Tryptophan

7 Acetone 8 Amide

9 Ccalcium carbonate 10 Sodium chloride

11 环己烷12 癸烷

13 丁醇14 钠

15 酪氨酸16 乙酸乙酯

17 汞18 酚

19 碳酸钾20 半胱氨酸

二、写出下列缩写的英文全称并翻译（共10分,每题2分）。

1 DMSO:

2 TCM:

3 GMP:

4 HPLC:

5 UV/visible: 答案： 1 dimethyl sulfoxide 二甲基亚砜

2 Traditional Chinese Medicine 中医

3 Good Manufacturing Practice 药品生产和质量管理规范

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4 High Performance (Pressure) Liquid Chromatography 高效液相色谱

5 Ultraviolet-visible spectroscopy 紫外分光光度法

三、判断，并用×√表示（共16分,每题2分）。

1 （）Analytical chemists also make important contributions to fields as diverse as forensics, archaeology, and space science.

2（）A selective reaction or test is one that occur only with the substance of interest.

3 （）Lead compounds can be obtained from a variety of different sources such as the flora and fauna of the natural world, or synthetic compounds made in the laboratory. There is also the potential of designing lead compounds using computer modeling or NMR spectroscopic studies.

4 （）Biomolecules are compounds of nitrogen.

5 （）By conyention, pharmacokinetics is defined as the study of the time-course of drug absorption, distribution, metabolism and excretion, whereas the term pharmacodynamics refers to the corresponding pharmacological response.

6 （）The degree of aqueous solubility of the drug affects directly the bioavailability of the drug.

7 （）Direct comparison with authentic (if available) should be carried out as final confirmation.

8 （）Drag design aims to remove the desirable effects of the lead compound and to improve the undesirable effects.

答案: 1 √ 2 × 3 √ 4 × 5 √ 6 ？7 √8 ×

四、单选题（共14分,每题2分）。

1 Qualitative analysis deals with the B of elements, ions, or compounds present in a sample (we may be interested in whether only a given substance is present)

A conclusion

B identification

C discipline

D instruction

2 Research programs based on the exploitation of A observations of side effects are of great interest in the discovery of new tracks in as they are based on

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information about activities observed directly in man and not in animals.

A clinical

B stable

C latentiation

D natural

3 B acids have carboxyl groups.

A aldehydes

B carboxylic

C alcohols

D amines

4 A conyention, pharmacokinetics is defind as the study of the time-course of drug absorption, distribution, metabolism and excretion, whereas the term pharmacodynamics refers to the corresponding pharmacological response.

A By

B In

C At

D With

5 Each drug product must be tests A with the dissolution test that best correlates to in vivo bioavailability.

A individually

B totally

C exhaustively

D quickly

6 With new compounds, however, it is preferable to confirm the identification through chemical degradation or by preparing the compound by B synthesis.

A microbiology

B laboratory

C organic D

7 C provides the methods and tools needed for insight into our material world…for answering four basic questions about a material sample:

①What

②Where

③How much

④What arrangement, structure or form?

A Medicinal Chemistry

B Phytochemistry

C Analytical chemistry

D Pharmacology

答案: 1 B 2 A 3 B 4 A 5 A 6 B 7 C

五、英译汉（共20分,每题5分）。

1 Functional groups determine chemical properties.

答案：官能团决定化学性质。

2 By conyention, pharmacokinetics is defined as the study of the time-course of drug absorption, distribution, metabolism and excretion, whereas the term

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pharmacodynamics refers to the corresponding pharmacological response.

答案：习惯上，药动学被定义为对药物的吸收，分布，代谢，排泄的过程的研究，而药效学指的是相关的药理反应。

3 Analytical chemistry seeks ever improved means of measuring the chemical composition of natural and artificial materials.

答案：分析化学旨在不断改善自然和人工材料的化学成分的方法。

4 In order to design a drug product that deliver the active drug in the most bioavailable form, the pharmacist must consider (1) the type of drug product (e.g. solution, suspension, suppository); (2) the nature of the excipients in the drug products; (3) the physicochemical properties of the drug molecule.

答案：为了设计一种使活性药物最有效的药物产品，药剂师必须考虑到 1 药品的剂型（例如，溶液剂、悬浮剂、栓剂）2 药品中辅料的性质 3 药物分子的物理化学性质。

六、问答题（共20分,每题5分）。

1 What is the means of Dissolution?

答案：Dissolution is the process by which a chemical or drug becomes dissolved in a solvents.

2 Why commercial absolute alcohol should be avoided?

答案：Since it contains residual benzene which absorbs in short UV.

3 What is the meanings of GMP?

答案：GMP is probably the most widespread quality system followed across the pharmaceutical industry as a whole.

4 What is lead compound?

答案：A lead compound will have some property considered therapeutically useful. The lead compound is not intended to be used as a clinical agent. It is the starting point from which a clinically useful compound can be developed.

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