PD184352 (CI-1040)_chemcatch_datasheet

3 years-20°C Powder

6 months

-80°C in DMSO

MEK2

17 nM

MEK1

17 nM

名称:PD184352 (CI-1040)

编号:CC1176

简述:

CI-1040 (PD 184352) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM, 100-fold more

selective for MEK1/2 than MEK5.

化学名称:2-(2-chloro-4-iodophenylamino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide

化学式:C H ClF IN O

分子量 (MW)478.67

CAS No.:212631-79-3

溶解度 (25°C) *

二甲基亚砜96mg/mL

水<1mg/mL

乙醇14mg/mL

稳定性:

化学描述：

CI-1040 (PD 184352) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM, 100-fold more selective for MEK1/2 than MEK5.

Phase 2.Quality confirmed by NMR & HPLC. See customer reviews, validations & product citations.

Targets：

IC50：

配置存储溶液:

1 mg5 mg10 mg

1 mM 2.0891 mL10.4456 mL20.891

2 mL

5 mM0.4178 mL 2.0891 mL 4.1782 mL

10 mM0.2089 mL 1.0446 mL 2.0891 mL

50 mM0.0418 mL0.2089 mL0.4178 mL

CC1176 PD184352 (CI-1040) Datasheet

For research use only !

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