中国数字医疗网论坛 -基于DICOM数据构建股骨三维有限元模型的精确力学分析☆ (1)

中国组织工程研究 第17卷 第30期 2013–07–23出版Chinese Journal of Tissue Engineering Research July 23, 2013 Vol.17, No.30doi:10.3969/j.issn.2095-4344.2013.30.011 []李峰，吴华. 基于DICOM 数据构建股骨三维有限元模型的精确力学分析[J].中国组织工程研究，2013，17(30):5483-5489.ISSN 2095-4344 CN 21-1581/R CODEN: ZLKHAH 5483www.CRTER .org李峰☆，男，1974年生，湖北省潜江市人，汉族， 2009年华中科技大学同济医学院毕业，博士，副主任医师，主要从事脊柱方面的研究。

lifengcnhb@ 中图分类号:R318 文献标识码:A 文章编号:2095-4344 (2013)30-05483-07收稿日期：2013-04-19 修回日期：2013-04-24 (201303110/G ·C)Li Feng ☆, M.D., Associate chief physician, Department of Orthopaedics andTraumatology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430074, Hubei Province, China lifengcnhb@Received: 2013-04-19 Accepted: 2013-04-24基于DICOM 数据构建股骨三维有限元模型的精确力学分析☆李 峰1，吴 华2 (1湖北省中医院骨伤科，湖北省武汉市 430074；2湖北武汉同济医院，湖北省武汉市 430030)文章亮点：1 作为骨科生物力学研究之中必不可少的重要工具之一，有限元方法己成为结构优化设计、材料非线性及几何非线性分析的一种实用而有效的应力分析方法。

2 文章运用Mimics 、ABQUS 软件，建立了一种快速精确构建股骨三维有限元模型的方法，提供更为简单有效的建模方式，可较大程度提高建模效率，为进一步构建理想的股骨模型提供了新思路。

3 通过与以往文献的比较发现，所建模型可以较好地表现骨关节等组织应力分布的总体趋势，与以往的研究结果相近，从而证实该模型可以用于今后的有限元分析。

关键词：骨关节植入物；数字化骨科；股骨；三维有限元；DICOM ；MIMICS ；ABQUS 6.8；应力；生物力学摘要背景：有限元模型已经由二维发展到三维，由线性模型发展到非线性，由于该方法在分析不太规则物体的力学特点方面具有优越性，因此在骨科生物力学研究特别是髋关节方面得到广泛应用。

目的：利用有限元方法分析人体股骨在载荷下的受力状态，探索一种快速建立股骨有限元模型并能进行精确力学分析的方法。

方法：选择标准成年男性志愿者行股骨CT 扫描成像，得到股骨每层横截面图像，应用DICOM 数据和MIMICS 软件行三维重建，结合有限元分析软件ABQUS 6.8构建股骨三维有限元模型，并分析股骨模型载荷状态下的应力分布。

结果与结论：结果显示，基于DICOM 数据建立的股骨三维有限元模型，划分网格后形成38 636个节点，201 422个单元，其中包括股骨松质骨体网格模型与皮质骨体网格模型。

有限元分析结果与以往的实验数据一致性较好，能够客观实际地反映股骨真实解剖形态和生物力学行为，分析精度较高。

提示运用Mimics 软件提供了简单有效的建模方法，极大程度上提高了建模效率，基于DICOM 数据的三维有限元模型几何形状较准确，可以为股骨正常力学行为研究提供精确模型。

利用ABQUS 6.8分析得到的应力分布情况与临床观察一致。

Precise mechanical analysis on the femoral three-dimensional finite element model constructed based on DICOM dataLi Feng 1, Wu Hua 2 (1Department of Orthopaedics and Traumatology, Hubei Provincial Hospital ofTraditional Chinese Medicine, Wuhan 430074, Hubei Province, China; 2Tongji Hospital of Wuhan, Wuhan 430030, Hubei Province, China)AbstractBACKGROUND: The finite element model has been developed from two-dimensional model tothree-dimensional model, from linear model to nonlinear model. As the advantage of this method in the analysis of mechanical characteristics of the irregular objects, the finite element model has been widely used in the research of orthopedic biomechanics, especially in the research of hip joint.OBJECTIVE: To analyze the stress state of human femur with finite element analysis method and to investigate a method that can rapidly construct femoral finite element model and precisely analyze the biomechanics.METHODS: Normal male femur was used as specimen for CT scan to obtain cross-sectional images of femur in each slice. Three-dimensional reconstruction was performed with DICOM data and MIMICS software, then the femoral three-dimensional finite element model was established with the finite element analysis ABQUS 6.8 software, and the stress distribution of the model was analyzed under loading condition.RESULTS AND CONCLUSION: Based on DICOM data, three-dimensional finite element model of femur was constructed more quickly and precisely. The models were divided into 38 636 nodes and 201 422 units. The model included the parts of cortical and cancellous bone. The biomechanical test results were accorded with the previous results, so the model could objectively reflect the real femur shape and biomechanical behavior with high precision. The Mimics software provided a simpler and effective method for the construction of femur model and improved the efficiency of modeling, and the three-dimensional finite element model based on DICOM data was accurate in shape and can be used for the normal research on biomechanical behavior of femur. The stress distribution analyzed with ABQUS 6.8 software is consistent with the clinical observation.P .O. Box 1200, Shenyang 110004 5484Key Words: bone and joint implants; digital orthopedics; femur; three-dimensional finite element; DICOM; MIMICS; ABQUS 6.8; stress; biomechanicsLi F, Wu H. Precise mechanical analysis on the femoral three-dimensional finite element model constructed based on DICOM data. Zhongguo Zuzhi Gongcheng Yanjiu. 2013;17(30):5483-5489.0 引言建立一个几何形态准确，解剖结构清晰的模型，是有限元受力分析的基础。

由于人体股骨结构形态不规则的形态特点，很难用常规的CAD 及CAE 软件来实现骨组织的三维重建，这是有限元分析的难点之一。

近年随着与计算机技术相关的有限元方法被引进骨科学的研究领域，能够迅速而有效地建立起骨骼的数学模型，并模拟骨骼的受力情况，对骨骼各个部位进行受力分析，对临床治疗提供依据。

Brekelmans 等[1]早在1972年首次将有限元方法应用于骨科生物力学的研究，且最先应用的是股骨；股骨是应力最为复杂的悬臂梁结构，对其生物力学特性的研究，可以为运动医学、骨科学及手术方法评定等提供可靠的理论指导[2-3]。