皮肤性病学英文 PPT课件
合集下载
皮肤性病学课件：淋病
治療原則 早期診斷 早期治療 規則用藥 治療方案要根據病情不同-----採取個體化。
自1943年青黴素問世，到1976年菲律賓首次分離出了
產β-內醯胺酶的耐青黴素淋球菌菌株---（PPNG）
淋球菌對青黴素的耐藥性--是因為菌株產生了 能→分解青黴素的β-內醯胺環。
狀觀黴素1971年由FDA批准用於治療淋病，1985年即 發現“耐藥株”----產β-內醯胺酶的PPNG 。
流出，→分泌物變為黃色膿性
• 尿痛 • 可伴發腹股溝淋巴結腫大
急性淋菌性前尿道炎
）
2.急性後尿道炎：
前尿道炎未經治療，2W後發展為急性後尿道炎，主要 為排尿刺激症狀加重。
1）如尿頻、尿急、尿痛，可出現終末血尿 2）會陰部墜脹 3）併發：前列腺炎、精囊炎、附睾炎、膀胱炎
慢性淋菌性尿道炎： 尿道炎症狀持續2月以上。
淋病
（ gonorrhea ）
性傳播疾病
（簡稱又叫性病）
（sexually transmitted disease STD）
➢定義： 是指---以通過直接性接觸為主 ----或類似性行為 ----及間接接觸（非性行為） 為傳播途徑的一組傳染性疾病。
病變：
----不僅發生在泌尿生殖器官，
---還可通過→淋巴系統--侵犯泌尿生殖器官所屬的淋巴結，
胸膜炎、心內膜炎、心包炎等。
一、男性淋病（急性與慢性）：
主要表現為-----“尿道炎”
（急性：前2W- 、後2W+， 慢性：全尿道-症狀持續2月以上)
急性尿道炎：
初為前尿道炎（2W內） 後尿道炎（2W後） 1.急性前尿道炎： • 早期症狀：尿道口輕度瘙癢、灼熱 • 尿道口輕度紅腫，2-3d後加重，有薄粘液
皮肤性病学湿疹英文课件
Etiology and pathogenesis
Internal factors External factors Hereditary tendency
eczema
Etiology and pathogenesis
Internal factors External factors
• chronic infection • block of blood circulation • change of endocrine and
Subacute eczema
• relieve from the above symptoms
• colors of eruption become dark
• scales • touch allergic things
again, acute condition will appear repeatedly • become chronic eczema
Acute
Subacute
Chronic
Subacute
Chronczema
• Intensely itching • Primary and multiform
lesions • The boundary is not
clear • Place symmetrically,
•Eruption place symmetrically
•Easy to recur and chronic
•Etiology-clear
•Lesion simple boundary clear
•Eruption place on only contact areas
•Self-limited, eliminating contact factors can be cured
皮肤性病学英文课件：08 Psoriasis
More common in youth & middle aged people Male>Female City>countryside North>South White race>yellow race>black race
Aetiology and Pathogenesis
Genetic factors: polygenic disease related HLA---A1,B13,B17,Cw6,etc
Environmental factors: infection, trauma (both mentally and physically), drug Immune factors: abnormal activation of T cells
with cytokines releasing (IL-1,IL-6,IL-8,TNF-a)
Auspitz sign
Psoriasis guttata
Psoriasis nummularis
Psoriasis annulata
Psoriasis rupioides
Psoriasis hypertrophica
Psoriasis zosteriformis
Psoriasis geographica
X-ray of psoriasis arthropathica
Osteoporosis Stenosis of joint
cavity Erosion of the joint
Psoriasis pustulosa localized generalized
Localized psoriasis pustulosa
Psoriasis
Aetiology and Pathogenesis
Genetic factors: polygenic disease related HLA---A1,B13,B17,Cw6,etc
Environmental factors: infection, trauma (both mentally and physically), drug Immune factors: abnormal activation of T cells
with cytokines releasing (IL-1,IL-6,IL-8,TNF-a)
Auspitz sign
Psoriasis guttata
Psoriasis nummularis
Psoriasis annulata
Psoriasis rupioides
Psoriasis hypertrophica
Psoriasis zosteriformis
Psoriasis geographica
X-ray of psoriasis arthropathica
Osteoporosis Stenosis of joint
cavity Erosion of the joint
Psoriasis pustulosa localized generalized
Localized psoriasis pustulosa
Psoriasis
皮肤性病学总论ppt课件
01
皮肤性病学概述
定义与特点
定义
皮肤性病学是一门研究皮肤疾病和性 传播疾病的学科。
特点
皮肤性病学涉及的疾病种类繁多，病 因复杂，临床表现多样，需要多学科 协作治疗。
皮肤性病学的历史与发展
古代
人类很早就开始对皮肤病进行 观察和治疗，如古埃及人用鳄 鱼粪便和蜂蜜治疗皮肤感染。
中世纪
欧洲教会和修道院开始对皮肤 病进行初步分类和研究。
感谢观看
THANKS
THE FIRST LESSON OF THE SCHOOL YEAR
心血管疾病与皮肤性病
肝病与皮肤性病
肝病患者的皮肤可能出现黄疸、瘙痒 等症状，与胆汁淤积、药物代谢等有 关。
心血管疾病患者可能并发血管炎、静 脉曲张等皮肤病。
皮肤性病与外科疾病的关系
创伤与皮肤性病
外科手术、烧伤、创伤等可能导致皮肤感染、瘢痕形成等。
肿瘤与皮肤性病
某些皮肤肿瘤可能与内脏肿瘤有关，如恶性黑色素瘤等。
皮肤性病学总论ppt 课件
THE FIRST LESSON OF THE SCHOOL YEAR
汇报人：可编辑
2024-01-11
目录CONTENTS
• 皮肤性病学概述 • 皮肤的结构与功能 • 皮肤性病的常见症状与体征 • 皮肤性病的诊断与治疗 • 皮肤性病与其他疾病的关系 • 皮肤性病学的研究进展与展望
免疫学诊断
利用抗原-抗体反应原理，检测皮肤相关抗 体或抗原，辅助诊断某些免疫性皮肤病。
皮肤性病的治疗方法
药物治疗
根据疾病的类型和严重程度，选择合适 的药物进行治疗，如外用药物、口服药
物和注射药物等。
手术治疗
对于某些严重的皮肤疾病，如皮肤肿 瘤等，可能需要手术切除或整复。
皮肤性病学课件：3_1带状疱疹英文教学
buring or deep, aching pain the shooting, lancinating pain the triggered pain
The pain severity is related to the age the affected area the extent of the skin lesions
Clinical manifestations
Prodrome:
headache and fever hyperaesthesia pain in the affected area
Features of lesions
initially presents as papules and plaques of erythema
There are may only neuralgia and papuloid lesions but with no blisters.
Complications
Postherpetic neuralgia(PHN) The pain persists after the skin
lesions have healed, with the same quality as that of acute zoster pain.
The incidence of herpes zoster increases with advancing age and decline in immune function.
Other than immunosuppression and age, the factors involved in reactivation are unknown.
The tendency to have persistant pain is age dependent.
The pain severity is related to the age the affected area the extent of the skin lesions
Clinical manifestations
Prodrome:
headache and fever hyperaesthesia pain in the affected area
Features of lesions
initially presents as papules and plaques of erythema
There are may only neuralgia and papuloid lesions but with no blisters.
Complications
Postherpetic neuralgia(PHN) The pain persists after the skin
lesions have healed, with the same quality as that of acute zoster pain.
The incidence of herpes zoster increases with advancing age and decline in immune function.
Other than immunosuppression and age, the factors involved in reactivation are unknown.
The tendency to have persistant pain is age dependent.
(皮肤性医学)13皮肤性病·ContactDermatitis
Nitric acid
Alkali
Subacute and chronic contact dermatitis
• Erythema(红斑), papule(丘疹), mild proliferation and lichenification(苔藓样变)
• Diaper dermatitis
•Allergic reaction type Ⅳ, delayed allergy
•Only a few people will be attacked who contact the allergen
• Characters:
▲ Incubation period(潜伏期)
▲ Easy to recur
Etiology and pathogenesis
mechanism
Irritant contact dermatitis
80%
Allergic contact dermatitis
20%
Allergic contact dermatitis
•Allergic contact dermatitis indicates an acquired sensitivity to various substances that produce inflammatory reactions in those, and only those who have been exposed to the allergen.
Diaper dermatitis
Dermatitis rhus
• Direct touch or indirect contact • Acute clinical features • Placed on exposed areas, erythema(红斑),
皮肤性病学英文课件：12 Bacterial infected skin diseases
◦ indirect immunological induction
psoriasis ,atopic dermatosis
Impetigo（脓疱疮）
Big pustle
Crust
➢ Pathogen: staphylococcus aurous 50%-70% beta hemolytic streptococcus
skin lesions extensive with fever and
lymphnoditis or weakness infant drug
sensitive test
sensitive antibiotic
➢ topical therapy：calamine lotion ，1：5000 potassium permanganate solution ,and mupirocin
➢ Prevalent season: summer/fall ➢ Onset age: infant/ old individual ➢ Diseased part: facial / hip ➢ Skin rash characteristic: blister、pustule、
honey gold crust. ➢ Bacterial test
Non impetigo bullosa differential diagnosis with varicella、papular urticaria
➢ prevention:
Personal Hygiene, keep skin dry, cure itch skin
disease .
➢ systemic therapy:
autoinoculation
psoriasis ,atopic dermatosis
Impetigo（脓疱疮）
Big pustle
Crust
➢ Pathogen: staphylococcus aurous 50%-70% beta hemolytic streptococcus
skin lesions extensive with fever and
lymphnoditis or weakness infant drug
sensitive test
sensitive antibiotic
➢ topical therapy：calamine lotion ，1：5000 potassium permanganate solution ,and mupirocin
➢ Prevalent season: summer/fall ➢ Onset age: infant/ old individual ➢ Diseased part: facial / hip ➢ Skin rash characteristic: blister、pustule、
honey gold crust. ➢ Bacterial test
Non impetigo bullosa differential diagnosis with varicella、papular urticaria
➢ prevention:
Personal Hygiene, keep skin dry, cure itch skin
disease .
➢ systemic therapy:
autoinoculation
皮肤性病学英文课件：08 Psoriasis
Main side-effects: monstrosity; dryness of skin and mucosa; abnormality of hepatic function and hyperlipemia
2.Cytotoxic drugs or immunosuppresive drugs: methotrexate(MTX), cyclosporin-a
normal skin islands in psoriasis erythrodermic
Diagnosis
Clinical manifestations,lesion features,involved positions and pathology examination
Treatment
5.Others: antibiotics, vitamins, traditional Chinese medicines
Photo therapy
NB-UVB:311nm UVA:320-400nm Main mechanisms: inhibition of proliferation of keratinocytes; vasodilation Main side-effects: short term: phototoxic reaction long term: skin aging; skin cancer
Derivatives of Vit D3: calcipotriol Retinoid acid: Tazarotene
Systemic treatment
1.Retinoids: etretinate(Tigason), acitretin(new Tigason) --- the first-line drugs
2.Cytotoxic drugs or immunosuppresive drugs: methotrexate(MTX), cyclosporin-a
normal skin islands in psoriasis erythrodermic
Diagnosis
Clinical manifestations,lesion features,involved positions and pathology examination
Treatment
5.Others: antibiotics, vitamins, traditional Chinese medicines
Photo therapy
NB-UVB:311nm UVA:320-400nm Main mechanisms: inhibition of proliferation of keratinocytes; vasodilation Main side-effects: short term: phototoxic reaction long term: skin aging; skin cancer
Derivatives of Vit D3: calcipotriol Retinoid acid: Tazarotene
Systemic treatment
1.Retinoids: etretinate(Tigason), acitretin(new Tigason) --- the first-line drugs
- 1、下载文档前请自行甄别文档内容的完整性，平台不提供额外的编辑、内容补充、找答案等附加服务。
- 2、"仅部分预览"的文档,不可在线预览部分如存在完整性等问题,可反馈申请退款(可完整预览的文档不适用该条件!)。
- 3、如文档侵犯您的权益，请联系客服反馈,我们会尽快为您处理(人工客服工作时间：9:00-18:30)。
Herpes Zoster
Definition
Herpes zoster is caused by Varicella - Zoster virus (VZV) , classically occurs unilaterally within the distribution of a sensory nerve, being characterized by clustered vesicles and considerable neuralgia.
Disseminated Herpes Zoster
A generalized varicelliform eruption accompanying the segmental eruption. It has been defined as more than 20 lesions outside the affected dermatome. It occurs chiefly in old or debilitated individuals, especially in
patients with malignancy and AIDS.
Diagnosis and Misdiagnosis Diagnosis
Typical lesions: crops of clustered vesicles surrounded
by erythema, forming in a discontinuous band, with enlarged regional lymph nodes. The distribution of a signal dorsal nerve root. Obvious neuralgia
Lesions may become hemorrhagic, necrotic, or bullous.
The vesicles slowly become pustulars, and rupture to form crusts , which separate in two to four weeks, often with scarring.
Over a few days, crops of clustered red papules form in a discontinuous band and quickly evolve to clear vesicles surrounded by erythema.
The eruption may have few lesions or reach total confluence in the dermatome.
The presenting features include : herpes auricularis, facial paralysis, and auditory symptoms.
Incomplete herpes zoster
There are may only neuralgia and papuloid lesions but with no blisters.
The regional lymph nodes are enlarged and tender.
Complications
Postherpetic neuralgia(PHN)
The pain persists after the skin lesions have healed, with the same quality as that of acute zoster pain.
Misdiagnosis:
Pain ususlly precedes the eruption by 3 or 4 days, sometimes it may be misdiagnosed to other diseases, depending on different part.
Appendicitis Cholecystitis Angina pectoris
Pathogen and Pathogenesis
en
Varicella-Zoster virus (VZV) is characterized by neurotropism and dermatotropism.
Pathogenesis
VZV causes varicella in childhood , and establishes latency in sensory ganglia after the primary infection. VZV may replicate later in life, taking advantage of the decline in immune function, traveling down the sensory nerve into the skin , showing neuralgia and clustered vesicles.
Clinical manifestations
Prodrome:
headache and fever hyperaesthesia pain in the affected area.
Features of lesions
The eruption presents as papules and erythema in the dermatome.
>a month
Ophthalmic Zoster
Ocular involvement is most commonly in the form of uveitis and keratitis.
Ramsay Hunt syndrome
Results from involvement of the facial and auditory nerves by the VZV.
Definition
Herpes zoster is caused by Varicella - Zoster virus (VZV) , classically occurs unilaterally within the distribution of a sensory nerve, being characterized by clustered vesicles and considerable neuralgia.
Disseminated Herpes Zoster
A generalized varicelliform eruption accompanying the segmental eruption. It has been defined as more than 20 lesions outside the affected dermatome. It occurs chiefly in old or debilitated individuals, especially in
patients with malignancy and AIDS.
Diagnosis and Misdiagnosis Diagnosis
Typical lesions: crops of clustered vesicles surrounded
by erythema, forming in a discontinuous band, with enlarged regional lymph nodes. The distribution of a signal dorsal nerve root. Obvious neuralgia
Lesions may become hemorrhagic, necrotic, or bullous.
The vesicles slowly become pustulars, and rupture to form crusts , which separate in two to four weeks, often with scarring.
Over a few days, crops of clustered red papules form in a discontinuous band and quickly evolve to clear vesicles surrounded by erythema.
The eruption may have few lesions or reach total confluence in the dermatome.
The presenting features include : herpes auricularis, facial paralysis, and auditory symptoms.
Incomplete herpes zoster
There are may only neuralgia and papuloid lesions but with no blisters.
The regional lymph nodes are enlarged and tender.
Complications
Postherpetic neuralgia(PHN)
The pain persists after the skin lesions have healed, with the same quality as that of acute zoster pain.
Misdiagnosis:
Pain ususlly precedes the eruption by 3 or 4 days, sometimes it may be misdiagnosed to other diseases, depending on different part.
Appendicitis Cholecystitis Angina pectoris
Pathogen and Pathogenesis
en
Varicella-Zoster virus (VZV) is characterized by neurotropism and dermatotropism.
Pathogenesis
VZV causes varicella in childhood , and establishes latency in sensory ganglia after the primary infection. VZV may replicate later in life, taking advantage of the decline in immune function, traveling down the sensory nerve into the skin , showing neuralgia and clustered vesicles.
Clinical manifestations
Prodrome:
headache and fever hyperaesthesia pain in the affected area.
Features of lesions
The eruption presents as papules and erythema in the dermatome.
>a month
Ophthalmic Zoster
Ocular involvement is most commonly in the form of uveitis and keratitis.
Ramsay Hunt syndrome
Results from involvement of the facial and auditory nerves by the VZV.