p53讲演(英文修改)
英语演讲带翻译3-5分钟
英语演讲带翻译3-5分钟英语演讲是一个自信和表达能力的体现，无论在学校还是职场中，都扮演着重要的角色。
但是因为英语不是母语的原因，很多人会面临演讲时的困难。
今天，我要分享一些关于英语演讲和翻译的技巧，帮助您准备一个精彩的英语演讲。
步骤一：选择一个主题首先，选择一个您感兴趣和了解的主题非常重要。
主题应该是适合受众并能引起他们的兴趣。
不要选择过于宽泛的话题，也不要选择个人私人生活方面的话题。
尽可能选择一个独特且具有现实意义的主题。
例如，您可以选择一些当前的社会热点事件或技术领域的话题，这样会更容易获得听众的关注。
步骤二：准备演讲内容在准备演讲内容时，请确保您熟悉所选主题的所有方面。
你需要准备事先的稿件或说话稿。
在准备稿件时，应注意以下几点：•在标题中突出重点，简洁明了地表达讲话的主旨•宣布自己的立场，让听众知道你希望他们从听你的演讲中学到些什么•使用例子来展示你的观点，让观众更容易理解。
•给出结论，包括让听众采取行动的建议，并再次突出重点。
在文稿准备时，应该使用简单的英语语言，以确保观众能够理解。
最好不要使用复杂的单词或语句。
您应该尽可能使用短语和简单句子以加强记忆，并保持流畅的表达。
步骤三：练习演讲准备工作完成后，您需要花时间练习演讲。
为了更好的表现，建议您练习多次。
这样做会让您更加自信，表现更加出色。
在练习时，还需要注意以下几点：•通过使用录音设备或视频记录您的讲话，可以了解您的说话速度、语音和姿势是否自然。
•您可以找一些志同道合的朋友或同事，邀请他们听您的演讲，并请他们给出宝贵建议。
•您还可以观看一些杰出的公共演讲家的演讲，学习他们的演讲风格和技巧。
步骤四：翻译自己的演讲如果您不是英语母语者，则需要考虑将演讲翻译成其他语言以便演讲时向听众传递您的看法。
在翻译时需要注意以下几点：•在选择翻译者时，应该找一位具有相应专业背景的翻译者，他们的翻译能力和生活经验将为您提供有用的帮助。
•翻译时需要充分理解初始语言的含义，并且在翻译的过程中，你应该注重准确的词句翻译，特别是针对专业词汇或术语。
提高演讲水平的英语课三五分钟演讲小故事演讲稿技巧
提高演讲水平的英语课三五分钟演讲小故事演讲稿技巧As a student, it is important to have good communication skills and to be able to speak confidently and convincinglyin front of a crowd. However, not all of us are natural-born speakers, and even those who are may still need some tips and techniques to improve their public speaking abilities.In this speech, I would like to share with you some stories, techniques and tips for improving your public speaking skills, based on my personal experience and research.First, let me share a story with you. When I firststarted giving speeches, I was always nervous and stumbledover my words. I felt as though I didn't have the rightskills to be a good public speaker. However, one day I was asked to give a speech at a big conference, and I decided to take a different approach. Instead of trying to memorizeevery word, I simply spoke from the heart and allowed my passion for the topic to come through. This made a big difference! I felt more confident and my audience responded positively to my message.From this experience, I learned that the best speeches come from the heart and involve telling stories, sharing experiences and connecting with your audience. Here are some more techniques that can help you improve your public speaking skills:1. Practice, Practice, PracticeThe most important thing you can do to improve your public speaking skills is to practice. Try recording yourself speaking and watch it back, paying attention to your tone, pacing, and body language. Also, try speaking in front of friends, family members or peers to get feedback on your performance.2. Organize Your ThoughtsBefore giving a speech, make sure to organize your thoughts coherently, including a clear introduction, body, and conclusion. This not only makes it easier for your audience to follow, but it also helps you stay on track and avoid going off on tangents.3. Use Visual AidsVisual aids can help illustrate and emphasize your key points. PowerPoint presentations, videos, infographics orflip charts can all be effective ways of communicating your message. Just be sure not to overuse them or let them overshadow your content.4. Pay Attention to Your Body LanguageBody language is an important aspect of public speaking, because it can either strengthen or weaken your message. Make sure you maintain eye contact, use gestures and facial expressions to help convey your message, and stand upstraight to project confidence.5. Connect With Your AudienceConnecting with your audience is key to engaging them and keeping their attention. You can do this by using humor, telling stories, and addressing their needs or concerns. Make sure you take the time to research your audience beforegiving your speech, so you can tailor your message accordingly.In conclusion, improving your public speaking skills takes practice and perseverance. By using these techniques and following these tips, you can become a confident and effective communicator in no time. Remember, the most important thing is to be yourself, speak from the heart, and connect with your audience.。
五年级英语五分钟演讲稿
五年级英语五分钟演讲稿As a fifth grade student, I have had the opportunity to learn English for five years. Today, I would like to share with you some of my thoughts on the importance of learning English.First of all, English is a global language. It is spoken by millions of people all over the world. When we learn English, we are able to communicate with people from different countries and cultures. This opens up a world of opportunities for us, both in our personal and professional lives.Secondly, learning English can help us access a wealth of knowledge and information. Many of the world's greatest works of literature, scientific research, and technological advancements are written in English. By mastering the language, we can read and understand these works, and stay informed about the latest developments in various fields.Furthermore, English is also the language of the internet. By being proficient in English, we can access a wide range of online resources, connect with people from around the world, and take advantage of the countless educational and entertainment opportunities that the internet has to offer.In addition, knowing English can also give us a competitive edge in the job market. Many companies require their employees to have a good command of English, and being fluent in the language can open up a wide range of career opportunities for us in the future.Moreover, learning English can also help us to become more open-minded and understanding of different cultures. By studying English literature and learning about the customs and traditions of English-speaking countries, we can gain a deeper appreciation for diversity and broaden our horizons.In conclusion, learning English is not just a subject we study in school, but a valuable skill that can enrich our lives in many ways. It is a tool that can open doors,connect us with the world, and empower us to pursue our dreams. I believe that by continuing to study English diligently, we can all become confident and proficient English speakers, and make the most of the opportunities that the language has to offer. Thank you.。
五分钟的演讲稿英语
五分钟的演讲稿英语good morning, ladies and gentlemen. i’d like to share my teaching dream with you. but before that, i want to say something about the beginning of this dream. in march this year, three teachers from australia came to our school. during the meeting, we exchanged a lot about education. i found that though we have almost the same teaching philosophy, we have different routines. what impressed me most was that their schools end at 3:00 in the afternoon and have no night classes. i can’t tell which kind of ro utine is better, but the sharp contrast made me think about a better education. the following is a dreamy school in my mind, in which there is no pressure but pleasure.in this school, the buildings are well designed, close to nature. in the morning, children can read while enjoying the beautiful sunrise. in the evening, they can exercise by the lake reflecting the amazing sunset. in the spring, they can go to the wild, lie on the lawn, and watch the kite flying in the blue sky. in the summer, they can go to the forest, live in a cabin, and listen to the rhythm of the rain. …students are free but polite and they respect each other. they can leave at 4:00 every afternoon, or perhaps earlier. they have the freedom to organize time. they can go to the library, go to the lab, the computer rooms or the playground. they’re self-motivated and have a strong thirst for knowledge. and there are no frequent exams and rankings. students won’t be forced to wear uniforms everyday, and there is no required hair style. everyday is so colorful that they are looking forward to the next day when going to bed at night,every teacher in this school can give a course as they like. there is no tedious rating, no scraps of quantitative management and no rigid standard. teachers can fully display their personality in class, and they feel very happy and content to teach. every morning, on thoughts of giving lessons, they are excited. after class, they are delighted , with smiles on their faces. some experts, scholars and masters are also visiting teachers in thisschool.yang zhenning can give physics classes for a day. yi zhongtian opens lectures on chinese culture for a week. speaking of music, we can ask wang lihong to give music lectures, just as he did in oxford university. if necessary, we can also invite david beckham to speak something about the world cup …the principal of the school focuses on education rather than waste time in endless meetings and social activities. teachers’ wages are not high but enough to live comfortably. there are no other things to do except to teach. there are no paper requirements, no titles and no ranks because they don’t need to be judged by those things. almost every teacher is a well-known scholar and master in a particular field. a language teacher may be a writer at the same time. a math teacher may try to overcome a world-class guess. a physics teacher can win invention awards and a music teacher may return from an international music competition again.in short, in this school, the principal is satisfied, the teachers are happy and the students are joyful. that’s my dream.in the matter of courage we all have our limits. there never was a hero who did not have his bounds. i suppose it may be said of nelson and all the others whose courage has been advertised that there came times in their lives when their bravery knew it had come to its limit.i have found mine a good many times. sometimes this was expected--often it was unexpected. i know a man who is not afraid to sleep with a rattle-snake, but you could not get him to sleep with a safety-razor.i never had the courage to talk across a long, narrow room. i should be at the end of the room facing all the audience. if i attempt to talk across a room i find myself turning this way and that, and thus at alternate periods i have part of the audience behind me. you ought never to have any part of the audience behind you; you never can tell what they are going to do.i'll sit down.feeling of youthno young man believes he shall ever die. it was a saying of my brother's, and a fine one. there is a feeling of eternity in youth, which makes us amend for everything. to be young is to be as one of the immortal gods. one half of time indeed is flown-the other half remains in store for us with all its countletreasures; for there is no line drawn, and we see no limit to our hopes and wishes. we make the coming age our own-the vast, the unbounded prospect lies before us.death. old age. are words without a meaning. that paby us like the ideaair which we regard not. others may have undergone, or may still be liable tothem-we "bear a charmed life“, which laughs to scorn all such sickly fancies. as in setting out on delightful journey, we strain our eager gaze forward-bidding the lovely scenes at distance hail!and see no end to the landscape, new objects presenting themselves as we advance; so, in the commencement of life, we set no bounds to our inclinations. nor to the unrestricted opportunities of gratifying them. we have as yet found no obstacle, no disposition to flag; and it seems that we can go on so forever. we look round in a new world, full of life, and motion, and ceaseleprogress; and feel in ourselves all the vigor and spirit to keep pace with it, and donot foresee from any present symptoms how we shall be left behind in thenatural course of things, decline into old age, and drop into the grave. it is the simplicity, and as it were abstractedneof our feelings in youth, that soto speak identifies us with nature, and our experience being slight and our passions strong deludes us into a belief of being immortal like it. our short-lives connection with existence we fondly flatter ourselves, is anindissoluble and lasting union-a honeymoon that knows neither coldness, jar,nor separation. as infants smile and sleep, we are rocked in the cradle of our wayward fancies, and lulled into security by the roar of the universe aroundus0we quaff the cup of life with eager haste without draining it, instead of which it only overflows the more-objects prearound us, filling the mind with their magnitude and with the strong of desires that wait upon them, so that we have no room for the thoughts of death.感谢您的阅读，祝您生活愉快。
高中英语Unit 5 Discovering Useful Structure P53
This is the book on which I spent 10 yuan. This is the book for which I paid 10 yuan.
② 根据先行词的搭配习惯。
pay 与 for 搭配
I still remember the day on which I first came to this
is our monitor.
先行词 关系词
Review of relative clauses
定语从句 先行词
• 修饰某一名词或代词的从句； • 一般跟在它所修饰的名词之后。
被定语从句所修饰的名词或代词。
关系词 引导定语
作用：1. 连接作用：连接主句与从句。 2. 成分作用：在定语从句中充当一个成分。 3. 替代作用：替代某一名词﹑代词或某一句话。
2. The English poem which / that the teacher mentioned in class was written by Byron. 先行词 关系词
3. The girl, whose poem won the first prize in the poetry contest,
主语
宾语
定语
指人
who/that
whom/who/that
whose
指物
which/that
which/that
whose
定语从句一般不用which作关系代词的几种情况：
1. 当先行词为all, little, much, few, every, everything, any, anything, no, nothing, none等不定代词或由它们修饰时，关 系代词多用that而which。
五分钟全英文演讲稿件
五分钟全英文演讲稿件Ladies and gentlemen, distinguished guests, and fellow students,Today, I stand before you to talk about a topic that is close to my heart –the power of education. Education is not just a means to acquire knowledge, but a tool that has the potential to transform individual lives and shape the future of nations.Firstly, let me emphasize the transformative power of education in the lives of individuals. Education offers us the opportunity to discover our true potential and pursue our dreams. It equips us with the necessary knowledge and skills to navigate the world and conquer challenges. Education is not limited to the classroom; it extends beyond textbooks and exams. It encourages critical thinking, nurtures creativity, and strengthens our ability to solve problems. Moreover, education instills values such as empathy, tolerance, and respect for diversity, creating responsible global citizens who contribute to the betterment of society.Furthermore, education has the power to break the chains of poverty and pave the way for social and economic development. It is crucial in reducing inequality, as it ensures equal opportunities for all, regardless of their background or circumstances. By providing education tounderprivileged communities, we empower them to becomeself-sufficient, break the cycle of poverty, and create a brighter future for themselves and their families. Education is not a privilege; it is a fundamental right of every individual and the cornerstone of a just and prosperous society.However, despite the undeniable importance of education, there are still millions of children around the world who do not have access to quality education. This is a tragedy that we must address together and strive to overcome. It is our responsibility as global citizens to advocate for equal access to education, to ensure that no child is left behind. We need to invest in educational infrastructure, train and motivate teachers, and support initiatives that promote inclusive and lifelong learning for all.In conclusion, education is a powerful force that can change lives and societies. It empowers individuals, eradicates poverty, and fosters peace and understanding. It is the key to unlocking our full potential and building a better world. Let us, therefore, ensure that education remains a top priority and strive to create a future where every child has the opportunity to learn and thrive.Thank you.。
英语5分钟演讲稿
英语5分钟演讲稿Good morning, everyone. Today I am going to talk about the importance of learning English.As we all know, English is one of the most widely spoken languages in the world. It is the official language of 53 countries and is spoken by around 1.5 billion people. In today's globalized world, English has become the lingua franca of business, science, technology, and international communication. Therefore, it is essential for us to learn English in order to thrive in this interconnected world.Firstly, learning English opens up a world of opportunities. Many multinational companies require their employees to be proficient in English, and being able to speak English can significantly increase one's job prospects and earning potential. In addition, English is the language of the internet, and being able to understand and communicate in English allows us to access a wealth of information and connect with people from all over the world.Secondly, learning English can broaden our horizons and enrich our lives. By learning English, we can access a vast amount of literature, films, music, and other forms of cultural expression that are not available in our native language. We can also travel to English-speaking countries and immerse ourselves in different cultures, which can be a truly eye-opening and enriching experience.Furthermore, learning English can improve our cognitive abilities and enhance our communication skills. Studies have shown that bilingual individuals have better problem-solving skills, multitasking abilities, and a greater capacity for learning new information. Additionally, being able to communicate in English allows us to connect with people from diverse backgrounds and build meaningful relationships.In conclusion, learning English is crucial in today's world. It opens up doors to new opportunities, enriches our lives, and enhances our cognitive abilities and communicationskills. Therefore, I urge everyone to take the time and effort to improve their English proficiency. Thank you.。
英语演讲稿改变自己
英语演讲稿改变自己As we all know, public speaking is an essential skill in today's society. Whether it's for a school presentation, a job interview, or a public event, the ability to deliver a compelling speech can truly change your life. In this document, we will explore how improving your English public speaking skills can have a profound impact on your personal and professional development.First and foremost, mastering the art of English public speaking can significantly boost your confidence. When you are able to articulate your thoughts and ideas in a clear and coherent manner, you will naturally feel more self-assured. This newfound confidence will not only benefit you in public speaking situations, but also in various other aspects of your life. You will find yourself more assertive in social interactions, more proactive in pursuing opportunities, and more resilient in facing challenges.Furthermore, improving your English public speaking skills can open up a world of opportunities for you. In today's globalized world, English is the lingua franca of business, education, and international communication. By honing your English public speaking abilities, you will be better equipped to connect with people from diverse backgrounds, participate in global forums and conferences, and access a wealth of knowledge and resources available in the English language.Moreover, becoming a proficient English public speaker can enhance your leadership potential. A great leader is not only knowledgeable and charismatic, but also an effective communicator. By mastering the art of English public speaking, you will be able to inspire and influence others, rally support for your ideas and initiatives, and ultimately, lead your team or organization to success.In addition, improving your English public speaking skills can boost your credibility and professional reputation. When you can express yourself eloquently and persuasively in English, you will be perceived as more competent and trustworthy. This can lead to greater career opportunities, increased visibility in your field, and a stronger personal brand.Last but not least, mastering English public speaking can enrich your personal growth and fulfillment. The process of crafting and delivering speeches in English will sharpen your critical thinking, creativity, and emotional intelligence. It will also provide you with a platform to share your thoughts and experiences, connect with others on a deeper level, and make a positive impact on the world around you.In conclusion, improving your English public speaking skills can truly change your life. It can boost your confidence, open up opportunities, enhance your leadership potential, boost your credibility, and enrich your personal growth. So, let's embrace the challenge of becoming better English public speakers, and unleash our full potential to change ourselves and the world.。
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the p53 protein binding to DNA
p53蛋白在避免癌症发生中扮演着重要的角色，例 蛋白在避免癌症发生中扮演着重要的角色， 蛋白在避免癌症发生中扮演着重要的角色 如，细胞凋亡 (apoptosis) 、基因组稳定性 (genetic stability) 、抑制血管新生 (angiogenesis) 。 受损时， 蛋白能活化 蛋白能活化DNA修复蛋白 当DNA受损时，p53蛋白能活化 受损时 修复蛋白 (DNA repair proteins)。 。 p53蛋白能抑制细胞生长周期 蛋白能抑制细胞生长周期(Inhibition of cell cycle) 蛋白能抑制细胞生长周期 停留于G1/S的节律点上，以达成 的节律点上， 损坏辨识。 若能 停留于 的节律点上 以达成DNA损坏辨识。 (若能 损坏辨识 将细胞于此节律点上停留够久， 将细胞于此节律点上停留够久，DNA修护蛋白将有更 修护蛋白将有更 充裕的时间修复DNA损坏部位，并继续细胞生长周 损坏部位， 充裕的时间修复 损坏部位 期。) 若细胞的DNA受损且不能修复，p53蛋白将起 受损且不能修复， 蛋白将起 若细胞的 受损且不能修复 动细胞凋亡程序， 动细胞凋亡程序，避免使不正常的细胞继续分裂生 活化的p53蛋白能接合 蛋白能接合DNA，促使多个基因表 长。活化的 蛋白能接合 ， 包括基因WAF1/CIP1，其为 蛋白之编码基 达，包括基因 ，其为p21蛋白之编码基 因。当p21蛋白 (WAF1) 与CDK2形成复合体时，细 蛋白 形成复合体时， 形成复合体时 胞将无法进入到细胞分裂阶段。 而突变后的p53蛋 胞将无法进入到细胞分裂阶段。 而突变后的 蛋 白将可能丧失与DNA形成有效结合的能力，导致 形成有效结合的能力， 白将可能丧失与 形成有效结合的能力 p21蛋白无法形成，不能发出停止细胞分裂的信号， 蛋白无法形成， 蛋白无法形成 不能发出停止细胞分裂的信号， 致使受损细胞不受控制的进行细胞分裂，最终形成 致使受损细胞不受控制的进行细胞分裂， 肿瘤。 肿瘤。
The p53 Signaling Pathway
The tumor-suppressor protein p53 exhibits sequence-specific DNAbinding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic stresses, e.g, UV irradiation or DNA damage, p53 is expressed and undergoes post-translational modification that results in its accumulation in the nucleus. The p53-dependent pathways help to maintain genomic stability by eliminating damaged cells either by arresting them permanently or through apoptosis. For example, g-irradiation activates p53 to turn on the transcription of p21CIP1, which, in turn, binds to and inhibits cyclin-dependent kinases, causing hypophosphorylation of retinoblastoma (Rb), thus preventing the release of E2F and blocking the G1-S transition. Some of the cellular effects of p53 can be blocked by the deregulated expression of c-Myc, Bcl-2, or E2F. p53 activity is controlled through an autoregulatory loop involving Mdm2. The binding of Mdm2 to p53 targets p53 for degradation and inhibits p53-induced cell-cycle arrest and apoptosis.
P53-----tumor suppressor gene
Introduction of p53
p53 ：the first 30 years The definition of p53 The genetic structure and expression of p53 The function of p53 protein The signaling pathways of p53
这种功能对于受化疗药物（chemotherapy drugs ） 这种功能对于受化疗药物 作用而受伤的癌细胞，则起到修复作用。 作用而受伤的癌细胞，则起到修复作用。 p53基因与人类一半以上的恶性肿瘤有关， 基因与人类一半以上的恶性肿瘤有关， 基因与人类一半以上的恶性肿瘤有关 如肝癌、乳腺癌、膀胱癌、胃癌、结肠癌、 如肝癌、乳腺癌、膀胱癌、胃癌、结肠癌、前 列腺癌、软组织肉瘤、卵巢癌、脑瘤、 列腺癌、软组织肉瘤、卵巢癌、脑瘤、淋巴细 胞肿瘤、食道癌、肺癌、成骨肉瘤等， 胞肿瘤、食道癌、肺癌、成骨肉瘤等，在这些 恶性肿瘤中都可观察到P53抑癌基因相关生化路 恶性肿瘤中都可观察到 抑癌基因相关生化路 径的失活。 径的失活。
P53介导的细胞信号转导途径 P53介导的细胞信号转导途径(cell signal transduction pathway) pathway) 在调节细胞正常生命活动中起重要作用, 在调节细胞正常生命活动中起重要作用,它与细胞内其它信号 转导通路间的联系十分复杂，其中P53参与调控的基因已超过 转导通路间的联系十分复杂，其中P53参与调控的基因已超过 160种，总体而言，其生物学功能(biological functions )可概括为： 160种 总体而言， 可概括为：
genetic therapy of p53
/nrc/focus/p53/index.html
p53是人体抑癌基因 tumor suppressor 是人体抑癌基因（ 是人体抑癌基因 gene），它因编码一种分子质量为 它因编码一种分子质量为53kDa的蛋 它因编码一种分子质量为 的蛋 白质而得名。 白质而得名。其表达产物为基因调节蛋白 蛋白）， 受到损伤时， （P53蛋白），当DNA受到损伤时，其表达产 蛋白），当 受到损伤时 物急剧增加，从而阻滞细胞周期。 物急剧增加，从而阻滞细胞周期。 p53不但可 不但可 以使癌细胞自杀，防止癌变； 以使癌细胞自杀，防止癌变；还具有帮助细胞 基因修复缺陷的功能， 基因修复缺陷的功能，
P53基因治疗 基因治疗
p53基因是研究最透彻，功能最强大的一种抑癌基因。 基因是研究最透彻，功能最强大的一种抑癌基因。 基因是研究最透彻 野生型p53对细胞周期 起关键性作用， 野生型 对细胞周期(cell cycle )和凋亡(apoptosis)起关键性作用， 尤其对经照射、 等刺击的癌细胞， 尤其对经照射、细胞毒制剂(cytotoxic agents)等刺击的癌细胞， 杀伤作用更为显著。 杀伤作用更为显著。2003年10月16日，国家食品药品监督管理 年 月 日 批准了重组人p53腺病 局(State Food and Drug Administration,SFDA)批准了重组人 腺病 毒注射液新药证书， 毒注射液新药证书，意味着世界上第一个癌症基因治疗药物 在中国诞生.重组人 腺病毒( 重组人p53腺病毒 在中国诞生 重组人 腺病毒 recombinant human p53 adenovirus) 是一种经基因工程改造过的活病毒，结构上分为两部分： 是一种经基因工程改造过的活病毒，结构上分为两部分：一 是抑癌基因p53，二是载体。 是抑癌基因 ，二是载体。载体是改造过的无复制能力的腺 病毒。这种携带p53的腺病毒特异感染肿瘤细胞 的腺病毒特异感染肿瘤细胞， 病毒。这种携带 的腺病毒特异感染肿瘤细胞，它能有效将 p53基因转入肿瘤细胞内，而对正常细胞无害。 基因转入肿瘤细胞内， 基因转入肿瘤细胞内 而对正常ll cycle ) 促进细胞调亡 (Promoting apoptosis) apoptosis) 维持基因组稳定(Maintaining genetic stability) 抑制肿瘤血管生成( 抑制肿瘤血管生成(Inhibition of tumor angiogenesis )