神经病学绪论PPT精品课程课件讲义

Nobel Prize
1991 ERWIN NEHER and BERT SAKMANN for their discoveries concerning the function of single ion channels in cells. They discovered a way to record and observe the ion channels or tunnel-like passageways from the inside to the outside of a cell. Their technique can be used in the study of such diseases as neuromuscular disorders, epilepsy and anxiety, and tailor-making a drug in order to achieve an optimal effect .
每年造成直接经济损失超过100亿元.
研究手段及方法日新月异 相关基础科学发展迅猛
神经科学
neuroscience
神经病学
neurology
神经眼科学 神经耳科学 神经心理学 神经内分泌学 神经肿瘤学 神经影像学
神经科学
neuroscience Anatomy 解剖学 Developmental biology 发育生物学 Biophysics 生物物理学 Pharmacology 药理学 Cell biology 细胞生物学 Molecular biology 分子生物学 Computer science 计算机科学 Psychology 心理学
nervous systБайду номын сангаасm, PNS) 及 骨 骼 肌 疾 病
(muscular diseases)的病因、发病机制、临
床表现、诊断、治疗及预防的一门临床医学
学科。
神经病学:最具发展前景的学科
解剖复杂、生理功能疑问众多
神经系统疾病发病率、 死亡率、致残率高
仅脑血管病发病率、 死亡率、致残率以及住院费用 居各项疾病前列,我国城市脑血管病居死亡原因首位,
美国把20世纪九十年代定为“脑的十 年”。 1997 年 19 个国家参与的“人类脑 计划”在美国正式启动。2001年9月，中 国正式成为参与“人类脑计划”的第 20 个国家。 诺贝尔奖多次授予神经科学家。
Nobel Prize
2000 ARVID CARLSSON, PAUL GREENGARD and ERIC KANDEL for their discoveries concerning signal transduction in the nervous system. He discovered that dopamine is a transmitter in the brain and that it has great importance for our ability to control movements and contributed to the development of L-dopa as a treatment for Parkinson‘s disease, to the understanding of the action of drugs for schizophrenia(精神分裂症), and the development of selective serotonin reuptake inhibitors ( 选 择 性 5-羟色胺再摄取 抑 制 剂 ) as antidepressants(抗抑郁剂).
神经系统疾病诊断
全面的相关知识 逻辑的思维方式 规范的检查手段 严谨的工作态度 全面的病史询问 系统的体格检查 准确的辅助诊断
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神经病学绪论
主讲：XX XX
凡大医治病，必当安神
定志，无欲无求，先发大慈恻 隐之心，誓愿普救含灵之苦。
- - 孙思邈
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神经病学 Neurology
是研究中枢神经系统 (central nervous system, CNS)、 周 围 神 经 系 统 ( peripheral
Nobel Prize
1994 ALFRED G. GILMAN and MARTIN RODBELL for their discovery of G-proteins and the role of these proteins in signal transduction in cells. They studied the complex relay(中继) of cell communication. G proteins, lying inside the cell, can respond to signals from outside the cell - light, smell, neurotransmitters and hormones - and translate them into a frenzy of cellular action inside.
Nobel Prize
1997 STANLEY B. PRUSINER for his discovery of Prions - a new biological principle of infection small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids and are responsible for Creutzfeldt-Jacob Disease，Kuru and certain other degenerative diseases of the nervous system. 朊蛋白：阻止修饰核酸的程序失活的蛋白质 性质的感染颗粒，是克－雅氏病、库鲁病及 其它某些神经系统变性病的病原体。