Oxytetracycline HCl MSDS盐酸土霉素英文安全技术说明书
化学品安全技术说明MSDS-6盐酸(中英文对照版本)
5.3.2 Hydrochloric acid1) Chemical Product and Company IdentificationMSDS Name: Hydrochloric Acid 37% SolutionCatalog Numbers: S71942, S71943, S74853, S74853SC, S80038, A142-212, A142P-20, A144-212, A144-500, A144-500LB, A144-612GAL, A144C-212, A144C-212EA, A144FP-500, A144P-20, A144P-500, A144S-212, A144S-212EA, A144S-500, A144SI-212, A466-1, A466-2, A466-250, A466-2LC, A466-500, A481-212, A481-212LC, A485-212, A485SAM1, A485SAM2, A485SAM3, A508-212, A508-212003, A508-212LC, A508-500, A5084, A508SK212, NC9532181, S71942SCMF, S71942SCND, S71943NDSynonyms: Muriatic acid; Chlorohydric acid; Hydrogen chloride; Spirits of saltRisk Phrases: 343) Hazards IdentificationEMERGENCY OVERVIEWAppearance: colorless to slight yellow. Danger! Corrosive. Causes eye and skin burns. May cause severe respiratory tract irritation with possible burns. May cause severe digestive tract irritation with possible burns. May cause fetal effects based upon animal studies. Possible sensitizer. May be harmful if swallowed. Hygroscopic. Target Organs: Teeth, circulatory system.Potential Health EffectsEye: May cause irreversible eye injury. Vapor or mist may cause irritation and severe burns. Contact with liquid is corrosive to the eyes and causes severe burns. May cause painful sensitization to light.Skin: May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Contact with liquid is corrosive and causes severe burns and ulceration. Ingestion: May cause circulatory system failure. Causes severe digestive tract burns with abdominal pain, vomiting, and possible death. May cause corrosion and permanent tissue destruction of the esophagus and digestive tract. May be harmful if swallowed.Inhalation: May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract. Exposure to the mist and vapor may erode exposed teeth. Causes corrosive action on the mucous membranes.Chronic: Prolonged or repeated skin contact may cause dermatitis. Repeated exposure may cause erosion of teeth. May cause fetal effects. Laboratory experiments have resulted in mutagenic effects. Prolonged exposure may cause conjunctivitis, photosensitization, and possible blindness.4) First Aid MeasuresEyes: Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes). SPEEDY ACTION IS CRITICAL!Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.Notes to Physician: Do NOT use sodium bicarbonate in an attempt to neutralize the acid.Antidote: Do NOT use oils or ointments in eye.5) Fire Fighting MeasuresGeneral Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Not flammable, but reacts with most metals to form flammable hydrogen gas. Use water spray to keep fire-exposed containers cool. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Reaction with water may generate much heat which will increase the concentration of fumes in the air. Containers may explode when heated. Extinguishing Media: For large fires, use water spray, fog, or alcohol-resistant foam. Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. Do NOT get water inside containers. Do NOT use straight streams of water. Most foams will react with the material and release corrosive/toxic gases. Cool containers with flooding quantities of water until well after fire is out. For small fires, use carbon dioxide (except for cyanides), dry chemical, dry sand, and alcohol-resistant foam.6) Accidental Release MeasuresGeneral Information: Use proper personal protective equipment as indicated in Section 8.Spills/Leaks: Large spills may be neutralized with dilute alkaline solutions of soda ash, or lime. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Provide ventilation. Do not get water inside containers. A vapor suppressing foam may be used to reduce vapors. Cover with dry earth, dry sand, or other non-combustible material followed with plastic sheet to minimize spreading and contact with water.7) Handling and StorageHandling: Wash thoroughly after handling. Remove contaminated clothing and washbefore reuse. Use only in a well-ventilated area. Contents may develop pressure upon prolonged storage. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Discard contaminated shoes. Use caution when opening. Keep from contact with moist air and steam.Storage: Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal containers. Store protected from moisture. Do not store near flammable or oxidizing substances (especially nitric acid or chlorates).8) Exposure Controls, Personal ProtectionEngineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.Vacated PELs are listed for this chemical.Personal Protective EquipmentEyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.Skin: Wear neoprene or polyvinyl chloride gloves to prevent exposure.Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR §1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.9) Physical and Chemical PropertiesPhysical State: Clear liquidAppearance: colorless to slight yellowOdor: strong, pungentpH: 0.01Vapor Pressure: 5.7 mm Hg @ 0 deg CVapor Density: 1.26Evaporation Rate:> 1.00 (N-butyl acetate)Viscosity: Not available.Boiling Point: 81.5-110 deg C @ 760 mmHgFreezing/Melting Point:-74 deg CAutoignition Temperature: Not applicable.Flash Point: Not applicable.Decomposition Temperature: Not available.NFPA Rating: (estimated) Health: 3; Flammability: 0; Reactivity: 1Explosion Limits, Lower: Not available.Upper: Not available.Solubility: Miscible.Specific Gravity/Density:1.0-1.2Molecular Formula: HCl. H2OMolecular Weight: 36.4610) Stability and ReactivityChemical Stability: Stable under normal temperatures and pressures.Conditions to Avoid: Mechanical shock, incompatible materials, metals, excess heat, exposure to moist air or water, bases.Incompatibilities with Other Materials: Bases, acetic anhydride, alkali metals, aluminum, amines, copper, copper alloys, fluorine, iron, sodium hydroxide, steel, sulfuric acid, vinyl acetate, zinc, potassium permanganate, cesium acetylene carbide, rubidium acetylene carbide, rubidium carbide, sodium, chlorosulfonic acid, oleum, carbonates, perchloric acid, calcium phosphide, metal oxides, acetates, cesium carbide, beta-propiolactone, ethyleneimine, propylene oxide, lithium silicides, alcohols + hydrogen cyanide, 2-aminoethanol, ammonium hydroxide, calcium carbide, 1,1-difluoroethylene, ethylene diamine, magnesium boride, mercuric sulfate, silver perchlorate + carbon tetrachloride, uranium phosphide.Hazardous Decomposition Products:Hydrogen chloride, chlorine, carbon monoxide, carbon dioxide, hydrogen gas.Hazardous Polymerization: Will not occur.11) Toxicological InformationRTECS#:CAS# 7647-01-0: MW4025000CAS# 7732-18-5: ZC0110000LD50/LC50:CAS# 7647-01-0:Inhalation, mouse: LC50 = 1108 ppm/1H;Inhalation, rat: LC50 = 3124 ppm/1H;Oral, rabbit: LD50 = 900 mg/kg;CAS# 7732-18-5:Oral, rat: LD50 = >90 mL/kg;Carcinogenicity:CAS# 7647-01-0:IARC: Group 3 carcinogen CAS# 7732-18-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.Epidemiology: Experimental reproductive effects have been reported. Teratogenicity: Embryo or Fetus: Stunted fetus, Inhalation, rat TCL0=450 mg/m3/1H Specific Developmental Abnormalities: homeostatis, Inhalation, rat TCL0=450 mg/m3/1H (female 1 days pre-mating).Reproductive Effects: No information available.Neurotoxicity: No information available.Mutagenicity: Cytogenetic analysis: Hamster, lung = 30 mmol/L.; Cytogeneticanalysis: Hamster, ovary = 8 mmol/L.Other Studies: No data available.12) Ecological InformationEcotoxicity: Fish: Bluegill/Sunfish: 3.6 mg/L; 48Hr; Lethal (unspecified) Bluegill/Sunfish: LC50; 96 Hr; pH 3.0-3.5 No data available.Environmental: Rapidly hydrolyzes when exposed to water. Will exhibit extensive evaporation from soil surfaces. Upon transport through the soil, hydrochloric acid will dissolve some of the soil materials (especially those with carbonate bases) and the acid will neutralize to some degree.Physical: No information available.Other: No information available.13) Disposal ConsiderationsChemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.RCRA P-Series: None listed.RCRA U-Series: None listed.US FEDERALTSCACAS# 7647-01-0 is listed on the TSCA inventory.CAS# 7732-18-5 is listed on the TSCA inventory.Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List.Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule.Section 12bNone of the chemicals are listed under TSCA Section 12b.TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA.SARASection 302 (RQ)CAS# 7647-01-0: final RQ = 5000 pounds (2270 kg)Section 302 (TPQ)CAS# 7647-01-0: TPQ = 500 pounds; RQ = 5000 pounds (does not meet toxi city criteria but because of high production volume and recognized tox icity is considered a chemical of concern)SARA CodesCAS # 7647-01-0: acute.Section 313This material contains Hydrogen chloride (CAS# 7647-01-0, 36 38%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.Clean Air Act:CAS# 7647-01-0 is listed as a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.Clean Water Act:CAS# 7647-01-0 is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA.OSHA:CAS# 7647-01-0 is considered highly hazardous by OSHA.STATECAS# 7647-01-0 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts.CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:CRisk Phrases:R 34 Causes burns.Safety Phrases:S 26 In case of contact with eyes, rinse immediatelywith plenty of water and seek medical advice.S 45 In case of accident or if you feel unwell, seekmedical advice immediately (show the label wherepossible).WGK (Water Danger/Protection)CAS# 7647-01-0: 1CAS# 7732-18-5: No information available.CanadaCAS# 7647-01-0 is listed on Canada's DSL List. CAS# 7647-01-0 is listed on Canada's DSL List. CAS# 7732-18-5 is listed on Canada's DSL List. CAS# 7732-18-5 is listed on Canada's DSL List.This product has a WHMIS classification of D2A, E.CAS# 7647-01-0 is listed on Canada's Ingredient Disclosure List.CAS# 7732-18-5 is not listed on Canada's Ingredient Disclosure List.Exposure LimitsCAS# 7647-01-0: OEL-AUSTRALIA:TWA 5ppm (7mg/m3) OEL-AUSTRIA:TWA 5ppm (7mg/m3) OEL-BELGIUM:STEL 5ppm (7.7mg/m3) OEL-DENMARK:STEL 5ppm (7mg/m3) OEL-FINLAND:STEL 5ppm (7mg/m3);Skin OEL-FRANCE:STEL 5ppm (7.5mg/m3) OEL-GERMANY:TWA 5ppm (7mg/m3) OEL-HUNGARY:STEL 5 mg/m3 OEL-JAPAN:STEL 5ppm (7.5mg/m3) OEL-THE NETHERLANDS:TWA 5ppm (7mg/m3) OEL-THE PHILIPPINES:TWA 5ppm (7mg/m3) OEL-POLAND:TWA 5 mg/m3 OEL-RUSSIA:STEL 5ppm (5mg/m3) OEL-SWEDEN:STEL 5ppm (8mg/m3) OEL-SWITZERLAND:TWA 5ppm (7.5 mg/m3);STEL 10ppm (15mg/m3) OEL-THAILAND:TWA 5ppm (7mg/m3) OEL-TURKEY:TWA 5ppm (7mg/m3) OEL-UNITED KINGDOM:TWA 5ppm (7mg/m3);STEL 5ppm (7mg/m3) OEL IN BULGARIA,COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV16) Additional InformationMSDS Creation Date: 7/06/1999Revision #2 Date: 8/02/2000The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.5.3.2盐酸1）化学品名称化学品中文名称：盐酸化学品英文名称：hydrochloric acid中文名称2：氢氯酸英文名称2：chlorohydric acid分子式：HCl分子量：36.46健康危害：接触其蒸气或烟雾，可引起急性中毒，出现眼结膜炎，鼻及口腔粘膜有烧灼感，鼻衄、齿龈出血，气管炎等。
盐酸安全技术说明书(MSDS)(完整资料).doc
【最新整理，下载后即可编辑】盐酸安全技术说明书（MSDS）盐酸安全技术说明书一标识中文名：盐酸英文名：hydrochloric acid分子式：HCl相对分子质量：36.46CAS号：7647-01-0危险性类别：第8.1 类酸性腐蚀品化学类别：酸类二主要组成部分与性状主要成分：36%氯化氢外观与性状：无色无臭透明液体，由于纯度不同，颜色自无色、黄色棕色，有时呈浑浊状。
主要用途：工业原料制作，工业金属冶炼等。
三健康危害侵入途径：吸入、食入。
健康危害：对皮肤、粘膜等组织烈的刺激和腐蚀作用。
蒸汽或雾可引起结膜水肿、角膜混浊，以致失明，引起呼吸道刺激，重者发生呼吸困难和肺水肿；高浓度引起喉痉挛或声门水肿而窒息死亡。
口服后引起消化道烧伤以致溃疡形成；严重者可能有胃穿孔、腹膜炎、肾损害、休克等。
皮肤灼伤轻者出现红斑，重者形成溃疡；溅入眼内可造成灼伤，甚至角膜穿孔、全眼失明。
四急救措施皮肤接触：脱去被污染的衣着，用流动的清水彻底冲洗皮肤。
眼睛接触：提起眼睑，用大量流动清水或生理盐水冲洗至少15分钟。
就医吸入：迅速脱离现场至空气新鲜处。
呼吸困难时给输氧。
如呼吸停止，立即进行人工呼吸。
就医。
食入：饮足量温开水，催吐，就医。
五燃爆特性与消防燃烧性：不易燃危险特性：能与一些活性金属粉末发生反应, 放出氢气。
遇氰化物能产生剧毒的氰化氢气体。
与碱发生中合反应，并放出大量的热。
具有较强的腐蚀性。
灭火方法：用碱性物质如碳酸氢钠、碳酸钠、消石灰等中和。
也可用大量水扑救。
六泄漏应急处理迅速撤离泄漏污染区人员至安全区，并进行隔离，严格限制出入。
建议应急处理人员戴自给正压式呼吸器，穿防酸碱工作服。
不要直接接触泄漏物。
尽可能切断泄漏源。
小量泄漏：用砂土、干燥石灰或苏打灰混合。
也可以用大量水冲洗，洗水稀释后放入废水系统。
大量泄漏：构筑围堤或挖坑收容。
用泵转移至槽车或专用收集器内，回收或运至废物处理场所处置。
七储运注意事项储存于阴凉、通风的库房。
盐酸安全技术说明书
【眼睛防护】：呼吸系统防护中已作防护。
【身体防护】：穿橡胶耐酸碱服。
【手防护】：戴橡胶耐酸碱手套。
【其他防护】：工作现场禁止吸烟、进食和饮水。工作完毕，淋浴更衣。单独存放被毒物污染的衣服，洗后备用。保持良好的卫生习惯。
【储运注意事项】：储存于阴凉、通风的库房。库温不超过30℃，相对湿度不超过85％。保持容器密封。应与碱类、胺类、碱金属、易（可）燃物分开存放，切忌混储。储区应备有泄漏应急处理设备和合适的收容材料。
【中国MAC】：15
【前苏联MAC】：未制定标准
【检测方法】：硫氰酸汞比色法
【工程控制】：密闭操作，注意通风。尽可能机械化、自动化。提供安全淋浴和洗眼设备。
【危险特性】：能与一些活性金属粉末发生反应, 放出氢气。遇氰化物能产生剧毒的氰化氢气体。与碱发生中合反应，并放出大量的热。具有较强的腐蚀性。
【灭火方法】：用碱性物质如碳酸氢钠、碳酸钠、消石灰等中和。也可用大量水扑救。
【泄漏应急处理】：迅速撤离泄漏污染区人员至安全区，并进行隔离，严格限制出入。建议应急处理人员戴自给正压式呼吸器，穿防酸碱工作服。不要直接接触泄漏物。尽可能切断泄漏源。小量泄漏：用砂土、干燥石灰或苏打灰混合。也可以用大量水冲洗，洗水稀释后放入废水系统。大量泄漏：构筑围堤或挖坑收容。用泵转移至槽车或专用收集器内，回收或运至废物处理场所处置。
【禁忌物】：碱类、胺类、碱金属、易燃或可燃物。
【燃烧分解产物】：
【急性毒性】：LD50：无资料，LC50：无资料
【刺激性】：
【亚急性和慢性毒性】：
【生殖毒性】：
【致癌性】：
盐酸土霉素简介
盐酸土霉素简介目录•1拼音•2英文参考•3盐酸土霉素药典标准o 3.1品名▪ 3.1.1中文名▪ 3.1.2汉语拼音▪ 3.1.3英文名o 3.2结构式o 3.3分子式与分子量o 3.4来源（名称）、含量（效价）o 3.5性状▪ 3.5.1比旋度o 3.6鉴别o 3.7检查▪ 3.7.1酸度▪ 3.7.2有关物质▪ 3.7.3杂质吸光度▪ 3.7.4水分o 3.8含量测定▪ 3.8.1色谱条件与系统适用性试验▪ 3.8.2测定法o 3.9类别o 3.10贮藏o 3.11制剂o 3.12版本•4盐酸土霉素说明书o 4.1盐酸土霉素的别名o 4.2外文名o 4.3盐酸土霉素的成分o 4.4性状o 4.5盐酸土霉素的药理作用o 4.6盐酸土霉素的适应症o 4.7盐酸土霉素的用量用法o 4.8注意事项o 4.9规格•附：o*盐酸土霉素相关药品说明书其它版本1拼音yán suān tǔ méi sù2英文参考oxytetracycline hydrochloride,terramycin hydrochloride[朗道汉英字典]3盐酸土霉素药典标准3.1品名3.1.1中文名盐酸土霉素3.1.2汉语拼音Yansuan Tumeisu3.1.3英文名Oxytetracycline Hydrochloride3.2结构式3.3分子式与分子量C22H24N2O9·HCl 496.903.4来源（名称）、含量（效价）本品为6甲基4（二甲氨基）3,5,6,10,12,12a六羟基1,11二氧代1,4,4a,5,5a,6,11,12a八氢2并四苯甲酰胺盐酸盐。
按无水物计算，含土霉素（C22H24N2O9）不得少于88.0%。
本品为黄色结晶性粉末；无臭，有引湿性；在日光下颜色变暗，在堿溶液中易破坏失效。
本品在水中易溶，在甲醇或乙醇中略溶，在三氯甲烷或乙醚中不溶。
3.5.1比旋度取本品，精密称定，加盐酸溶液（9→1000）溶解并定量稀释制成每1ml中约含10mg的溶液，避光放置1小时，依法测定（2010年版药典二部附录Ⅵ E），比旋度为188°至200°。
盐酸安全技术说明书
盐酸安全技术说明书（MSDS）第一部分标识中文名：盐酸英文名：hydrochloric acid分子式：HCl相对分子质量：36.46CAS号：7647-01-0危险性类别：第8.1 类酸性腐蚀品化学类别：酸类第二部分主要组成部分与性状主要成分：36%氯化氢外观与性状：无色无臭透明液体，由于纯度不同，颜色自无色、黄色棕色，有时呈浑浊状。
主要用途：工业原料制作，工业金属冶炼等。
第三部分健康危害侵入途径：吸入、食入。
健康危害：对皮肤、粘膜等组织烈的刺激和腐蚀作用。
蒸汽或雾可引起结膜水肿、角膜混浊，以致失明，引起呼吸道刺激，重者发生呼吸困难和肺水肿；高浓度引起喉痉挛或声门水肿而窒息死亡。
口服后引起消化道烧伤以致溃疡形成；严重者可能有胃穿孔、腹膜炎、肾损害、休克等。
皮肤灼伤轻者出现红斑，重者形成溃疡；溅入眼内可造成灼伤，甚至角膜穿孔、全眼失明。
第四部分急救措施皮肤接触：脱去被污染的衣着，用流动的清水彻底冲洗皮肤。
眼睛接触：提起眼睑，用大量流动清水或生理盐水冲洗至少15分钟。
就医吸入：迅速脱离现场至空气新鲜处。
呼吸困难时给输氧。
如呼吸停止，立即进行人工呼吸。
就医。
食入：饮足量温开水，催吐，就医。
五燃爆特性与消防燃烧性：不易燃危险特性：能与一些活性金属粉末发生反应, 放出氢气。
遇氰化物能产生剧毒的氰化氢气体。
与碱发生中合反应，并放出大量的热。
具有较强的腐蚀性。
灭火方法：用碱性物质如碳酸氢钠、碳酸钠、消石灰等中和。
也可用大量水扑救。
第六部分泄漏应急处理迅速撤离泄漏污染区人员至安全区，并进行隔离，严格限制出入。
建议应急处理人员戴自给正压式呼吸器，穿防酸碱工作服。
不要直接接触泄漏物。
尽可能切断泄漏源。
小量泄漏：用砂土、干燥石灰或苏打灰混合。
也可以用大量水冲洗，洗水稀释后放入废水系统。
大量泄漏：构筑围堤或挖坑收容。
用泵转移至槽车或专用收集器内，回收或运至废物处理场所处置。
第七部分储运注意事项储存于阴凉、通风的库房。
10%盐酸土霉素可溶性粉
盐酸土霉素可溶性粉说明书
兽用非处方药
【兽药名称】通用名称：盐酸土霉素可溶性粉
商品名称：无
英文名称：Oxytetracycline Hydrochloride Soluble Powder
汉语拼音：Yansuan Tumeisu Kerongxingfen
【主要成分】盐酸土霉素。
【性状】本品为淡黄色粉末。
【药理作用】四环素类抗生素。
土霉素通过可逆性地与细菌核糖体30S亚基上的受体结合，干扰tRNA与mRNA形成核糖体复合物，阻止肽链延长而抑制蛋白质合成，从而使细菌的生长繁殖迅速被抑制。
土霉素对革兰氏阳性菌和阴性菌均有抑制作用。
细菌对土霉素和多西环素存在交叉耐药性。
【适应证】用于治疗猪、鸡敏感大肠杆菌、沙门氏菌、巴氏杆菌及支原体引起的感染性疾病。
【用法与用量】以土霉素计。
混饮：每1L水，猪100～200mg，鸡150～250mg。
连用3～5日。
【不良反应】长期应用可引起二重感染和肝脏损害。
【注意事项】1、本品不宜与青霉素类药物和含钙盐、铁盐及多价金属离子的药物或饲料合用。
2、与强利尿药同用可使肾功能损害加重。
3、不宜与含氯量多的自来水和碱性溶液混合。
4、肝功能严重受损的患畜禁用。
【休药期】猪7日；鸡5日，弃蛋期2日。
【规格】10%
【包装】500g
【贮藏】遮光，密闭，干燥处保存。
【有效期】2年
【生产日期】见喷码
【生产批号】见喷码
【有效期至】见喷码。
盐酸安全技术说明书(msds)
81013
UN编号：
1789
IMDG规则页码：
无资料
包装标志：
无资料
包装类别：
O52
包装方法：
无资料
运输注意事项：
本品铁路运输时限使用有像胶衬里钢制罐车或特制塑料企业自备罐车装运，装运前需报有关部门批准。铁路运输时应严格按照铁道部《危险货物运输规则》中的危险货物配装表进行配装。起运时包装要完整，装载应稳妥。运输过程中要确保容器不泄漏、不倒塌、不坠落、不损坏。严禁与碱类、胺类、碱金属、易燃物或可燃物、食用化学品等混装混运。运输时运输车辆应配备泄漏应急处理设备。运输途中应防曝晒、雨淋，防高温。公路运输时要按规定路线行驶，勿在居民区和人口稠密区停留。
无资料
有害燃烧产物：
氯化氢。
灭火方法：
用碱性物质如碳酸氢钠、碳酸钠、消石灰等中和。也可用大量水扑救。
第六部分：泄漏应急处理
应急处理：
用碱性物质如碳酸氢钠、碳酸钠、消石灰等中和。也可用大量水扑救。
第七部分：操作处置与储存
操作注意事项：
密闭操作，注意通风。操作尽可能机械化、自动化。操作人员必须经过专门培训，严格遵守操作规程。建议操作人员佩戴自吸过滤式防毒面具（全面罩），穿橡胶耐酸碱服，戴橡胶耐酸碱手套。远离易燃、可燃物。防止蒸气泄漏到工作场所空气中。避免与碱类、胺类、碱金属接触。搬运时要轻装轻卸，防止包装及容器损坏。配备泄漏应急处理设备。倒空的容器可能残留有害物。
OSHA 5ppm,7.5[上限值]
TLVWN：
ACGIH 5ppm,7.5mg/m3
接触限值：
无资料
监测方法：
硫氰酸汞比色法
工程控制：
密闭操作，注意通风。尽可能机械化、自动化。提供安全淋浴和洗眼设备。
盐酸土霉素胶囊使用说明书
盐酸土霉素胶囊使用说明书请仔细阅读说明书并在医师指导下使用盐酸土霉素胶囊使用说明书【药品名称】通用名称：盐酸土霉素胶囊英文名称：Oxytetracycline Hydrochloride Capsules汉语拼音：YansuanTumeisuJiaonang【成份】本品含盐酸土霉素按土霉素计算，应为标示量的90.0%～110.0%。
【性状】本品为胶囊剂，内容物显黄色。
【适应症】1.本品可作为下列疾病的选取用药物：(1)立克次体病，包括流行性斑疹伤寒、地方性斑疹伤寒、洛矶山热、恙虫病和Q热；(2)支原体属感染；(3)衣原体属感染，包括鹦鹉热、性病、淋巴肉牙肿、非特异性尿道炎、输卵管炎、宫颈炎及沙眼；(4)回归热；(5)布鲁菌；(6)霍乱；(7)兔热病；(8)鼠疫；(9)软下疳。
治疗布鲁菌病和鼠疫时需与氨基糖苷类联合应用。
2．由于目前常见致病菌对本品耐药现象严重，仅在病原菌对本品敏感时，可作为选用药物：对本品敏感的大肠埃希菌、产气肠杆菌、洛菲不动杆菌、志贺菌属、流感嗜血杆菌（仅限于呼吸道感染）和克雷伯菌属（限于呼吸道和泌尿道感染）等革兰阴性杆菌感染。
本品不宜用于任何类型的葡萄球菌或溶血性链球菌感染。
3．本品可用于对青霉素类过敏的破伤风、气性坏疽、雅司、梅毒、淋病和钩端螺旋体病以及放线菌属、李斯特菌感染的患者。
4．可用于急性肠道阿米巴病和中、重度痤疮患者作为辅助治疗。
【规格】每粒重 0.25g 。
【不良反应】1、消化系统：胃肠道症状如恶心、呕吐、上腹不适、腹胀、腹泻，偶有胰腺炎、食管炎和食管溃疡的报道，多发生于服药后立即卧床的患者。
2、肝毒性：通常为脂肪肝变性，妊娠期妇女、原有肾功能损害的患者易发生肝毒性，但肝毒性亦可发生于并无上述情况的患者。
3、过敏反应：多为斑丘疹和红斑，此外可见荨麻疹、血管神经性水肿、过敏性紫癜、心包炎以及系统性红斑狼疮加重，表皮剥脱性皮炎并不常见。
偶有过敏性休克和哮喘发生。
某些用四环素的患者日晒时有光敏现象。
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Material Safety Data Sheet
Identification of the Substance
Chemical name:
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a
hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide HCL
Product name: Oxytetracycline HCL
Chemical formula: C22H24N2O9·HCL
Company indentification: Shandong Jinyang Biological Pharmaceutical Co.,Ltd.
Add: No.45, Yumin Road, High & New Tech Development Zone of Zibo, Shandong, China
Possible hazards
Critical hazards to man and the environment: NL
First aid measures
General advice: Remove from exposure and contaminated clothing, obtain
immediately medical attention in case of hypersensitivity reactions.
On skin and/or eye contact : wash thoroughly with plenty of water.
On ingestion : if breathing is difficult ,give oxygen.
Fire fighting measures
Suitable extinguishing media : water or dry ice
Unsuitable extinguishing media: the material has no
Explosive character
Accidental release measures
Personal precautions: wash with plenty of water.
Handling and storage
Storage: Storage in tightly closed container at a temperature not exceeding 40℃,adold contact with eyes and skin
Exposure controls and personal protection additional information on the lay-out of technical plant
Personal protective equipment
Respiratory protection : wear approved respirator
Hand protection : use chemically compatible gloves
Eyes protection : protect eyes with approved goggles
Body protection : use approved protective clothes
General safety and hygiene measures : follow the general safety and hygiene
measures for chemicals which are used as
drugs.
Physical and chemical properties
Form :crystalline powder
Color :yellow
Odor :almost odorless
Change in physical state
Melting point / Melting range :184.5℃-185.5℃
Boiling point/Boiling range : N.A. (DIN)
Flash point : N.A. (DIN)
Combustibility : N.A. (DIN)
Ignition temperature : Deg.C (DIN)
Self-ignition temperature : Deg.C (DIN)
Fire promoting properties :Nil
Density : (Deg.C)
Bulk Density : 1.634/20℃
Solubility in water :(Deg.C) Slightly soluble
Solubility in other solvents : Methanol : Soluble
Ethanol : Soluble
0.1N Hcl : Soluble
PH Value : 8.5-9.0
Octanol / water partition coefficient (LOG.POW)
Viscosity : Deg.C
Stability and reactivity
Conditions to avoid : Not to expose to high temperature
(above 50℃)
Substances to avoid : Not to allow to come in contact with
Any other chemical substances .
Hazardous reactions : Oxidative combustion
Hazardous decomposition :The material will be Decomposed when
exposed in sunlight or fumes.
Toxicological information
Acute toxicity
Ld50 / oral / mouse : N.A.
Ld50 / inhal /rat : Mg /1/H
Other information : Not established and as such is a very
safe material
Disposal Considerations : In accordance with state and local law
On product oxytetracycline
Other information
The information contained herein is based on the present state of our knowledge and does not therefore guarantee certain properties. recipients of our product must take responsibility for observing existing laws and regulations.。