华中科技大学同济医学院博一英语考试参考样体
华中科技大学博士研究生入学考试《英语专业综合》考试大纲
华中科技大学博士研究生入学考试《英语专业综合》考试大纲
（科目代码： 3556 ）
一、考试性质
英语专业综合的评价标准是高等学校优秀硕士毕业生能够达到的水平，以保证被录取者具有较为扎实的英语语专业知识。
考试对象为参加全国博士研究生入学考试的准考考生。
二、考试形式与试卷结构
（一）答卷方式：闭卷，笔试，用英语答题。
（二）答题时间：180分钟
（三）题型：论述题
（四）内容比例
1、理论语言学 50%
备注：考察学理论语言学与应用语言学的基本理论、流派及其发展和分析方法。
要求考生熟练掌握语言学理论的基本概念和原理，以及语言学和其他学科的联系，并具备综合运用所学知识分析具体语言现象、解决实际问题的能力。
2、专业方向题 50%
备注：外语教育、翻译与跨文化交际这三个研究方向分别有两道论述题，考生根据报考方向选做2道。
华科2021博士入学英语试题_及参考答案
华科2021博士入学英语试题_及参考答案华科2021博士入学英语试题及参考答案Passage 1Recent years have brought minority-owned businesses in the United States unprecedented opportunities - as well as new and significant risks. Civilrights activists have long argued that one of the principal reasons why Blacks, Hispanics, and other minority groups have difficulty establishing themselvesin business is that they lack access to the sizable orders and subcontractsthat are generated by large companies. Now Congress, in apparent agreement,has required by law that businesses awarded federal contracts of more than $500,000 do their best to find minority subcontractors and record theirefforts to do so on forms filed with the government. Indeed, some federal and local agencies have gone so far as to set specific percentage goals for apportioning parts of public works contracts to minority enterprises.Corporate response appears to have been substantial. According to figures collected in 1977, the total of corporate contracts with minority businesses rose from $77 million in 1972 to $1.1 billion in 1977. The projected total of corporate contracts with minority businesses for the early 1980's is estimated to be over 53 billion per year with no letup anticipated in the next decade. Promising as it is for minority businesses, this increased patronage poses dangers for them, too. First, minority firms risk expanding too fast and overextending themselves financially, since most are small concerns and,unlike large businesses, they often need to make substantial investments innew plants, staff, equipment, and the like in order to perform work subcontracted to them. If, thereafter, their subcontracts are for some reason reduced, such firms can face potentially crippling fixed expenses. The worldof corporate purchasing can be frustrating for small entrepreneurs who get requests for elaborate formal estimates and bids. Both consume valuable time and resources, and a small company's efforts must soon result in orders, or both the morale and the financial health of the business will suffer.A second risk is that White-owned companies may seek to cash in on the increasing apportionments through formation of joint ventures with minority-owned concerns. Of course, in many instances there are legitimate reasons forjoint ventures; clearly, White and minority enterprises can team up to acquire business that neither could acquire alone. But civil rights groups andminority business owners have complained to Congress about minorities being set up as “fronts (a person, group, or thing used to mask the identity or true character or activity of the actual controlling agent)” with White backing, rather than being accepted as full partners in legitimate joint ventures.Third, a minority enterprise that secures the business of one large corporate customer often runs the danger of becoming-and remaining-dependent. Even in the best of circumstances, fierce competition from larger, more established companies makes it difficult for small concerns to broaden their customer bases: when such firms have nearly guaranteed orders from a single corporate benefactor, they may truly have to struggle against complacency arising from their current success.11. The primary purpose of the text is to[A] present a commonplace idea and its inaccuracies.[B] describe a situation and its potential drawbacks. [C] propose a temporary solution to a problem. [D] analyze a frequent source of disagreement.2. The text suggests that the failure of a large business to have its bids for subcontracts result quickly in orders might causes it to[A] experience frustration but not serious financial harm. [B] face potentially crippling fixed expenses.[C] have to record its efforts on forms filed with the government. [D] increase its spending with minority subcontractors.3.The author would most likely agree with which of the following statements about corporate response to working with minority subcontractors?[A] Annoyed by the proliferation of “front” organizations, corporations are likely to reduce their efforts to work with minority-owned subcontractors in the near future.[B] Although corporations showed considerable interest in working with minority businesses in the 1970’s, their aversion to government paperwork made them reluctant to pursue many government contracts.[C] The significant response of corporations in the 1970’s is likely to be sustained and conceivably be increased throughout the 1980’s.[D] Although corporations are eager to cooperate with minority-owned business es, a shortage of capital in the 1970’s made substantial response impossible4 According to the text, civil rights activists maintain that one disadvantage under which minority-owned businesses have traditionally had to labor is that they have[A] been especially vulnerable to government mismanagement of the economy.[B] been denied bank loans at rates comparable to those afforded larger competitors.[C] not had sufficient opportunity to secure business created by large corporations.[D] not been able to advertise in those media that reach large numbers of potential customers.5 The author implies that a minority-owned concern that does the greater part of its business with one large corporate customer should[A] avoid competition with larger, more established concerns by not expanding. 【B】 concentrating on securing even more business from that corporation. [C] use its influence with the corporation to promote subcontracting with other minority concerns.[D] try to expand its customer bases to avoid becoming dependent on the2corporation.Passage 2Years of research had educated me about how sugar, fat, and salt changethe brain. I understood some of the parallels between hyperpalatable foods and drugs of abuse, and about the links among sensory stimulation, cues, and memory. I'd met enough people like Claudia and Maria to understand how eventhe thought of food could cause them to lose control.But I wasn't fully prepared for the discoveries I made aboutirresistibility and whoosh, the Monster Thickburger and Baked! Cheetos Flamin' Hot, about indulgence and purple cows. Without necessarily understanding the underlying science, the food industry has discovered what sells.I was sitting at Chili's Grill & Bar in Chicago's O'Hare Airport waitingfor a late-night flight. At a nearby table a couple in their early forties was deep into a meal. The woman was overweight, with about 180 pounds on her five-foot-four-inch frame. The Southwestern Eggrolls she had ordered were listed as a starter course, but the enormous platter in front of her had been heapedwith food. The dish was described on the menu as \chicken, black beans, corn, jalape?o Jack cheese, red peppers, and spinach wrapped inside a crispy flour tortilla,\and it was served with a creamy avocado-ranch dipping sauce. Despite its name, the dish looked more like a burrito than an egg roll, an only-in-America fusion approach.I watched as the woman attacked her food with vigor and speed. She heldthe egg roll in one hand, dunked it into the sauce, and brought it to hermouth while using the fork in her other hand to scoop up more sauce. Occasionally she reached over and speared some of her companion's french fries. The woman ate steadily, working her way around the plate with scant pause for conversation or rest. When she finally paused, only a little lettuce was left.Had she known someone was watching her, I'm sure she would have eaten differently. Had she been asked to describe what she had just eaten, she probably would have substantially underestimated her consumption. And shewould probably have been surprised to learn what the ingredients in her meal really were.The woman might have been interested in how my industry source, who had called sugar, fat, and salt the three points of the compass, described her entree. Deep-frying the tortilla drives down its water content from 40 percentto about 5 percent and replaces the rest with fat. \is supposed to look, which is crispy and brown on the outside.\The food consultant read through other ingredients on the label, keeping up a running commentary as he did. \. People like smoky flavor ― it's the caveman in them.\\eating something healthy.\\off the chart.\3The hot peppers, he said, \He believed the chicken had been chopped and formed much like a meat loaf, with binders added, which makes those calories easy to swallow. Ingredients that hold moisture, including autolyzed yeast extract, sodium phosphate, and soy protein concentrate, further soften the food. I noticed that salt appeared eight times on the label and that sweeteners were there five times, in the form of corn-syrup solids, molasses, honey, brown sugar, and sugar.\\yes. All of this has been processed such that you can wolf it down fast...chopped up and made ultrapalatable.... Very appealing looking, very high pleasure in the food, very high caloric density. Rules out all that stuff you have to chew.\By eliminating the need to chew, modern food processing techniques allow us to eat faster. \it,\mouth.1. It can be inferred from the author's description of the woman eating in paragraph four that(A) The woman prefers to eat at Chili's vs. other restaurants. (B) The woman truly enjoys the foods that she chooses to eat.(C) The woman's efficiency at cleaning her plate adds to her dining experience. (D) The author is disgusted by the woman's consumption.(E) The author believes the woman should take a course in healthy eating.2. According to the passage, the main reason people overeat is(A) because salt and sweeteners, like corn-syrup solids and brown sugar, are added to the food.(B) because we don't have to chew our food very much (C) because people like smoky flavor(D) because sugar, fat and salt change the brain(E) because we are used to eating quickly in this modern society 3. The following are all ingredients in the egg rolls, EXCEPT(A) salt (B) binders (C) honey (D) spinach (E) dark meat chicken4. Which of the following statements best describes the main idea of the passage?(A) If you eat too much food too quickly, you'll gain weight and become unhealthy.(B) Because refined food is irresistible and easy to eat, it masks how unhealthy it is, leaving people unaware of the poor food choices they're making.(C) Chili's is one of the restaurants in the U.S. serving unhealthy food to consumers today. (D) Food consultants and authors are making Americans aware of their unhealthy eating habits, thus, creating healthier generations for years to come.(E) Refined foods, with salt, sugar, and fat hidden inside, are less nutritious and more damaging than whole foods.5. In the first sentence of paragraph four, the word \ (A) pleasure (B) flamboyance (C) lethargy (D) energy (E) craftiness4Passage 3No very satisfactory account of the mechanism that caused the formation of the ocean basins has yet been given.The traditional view supposes that the upper mantle of the earth behaves as a liquid when it is subjected to small forces for long periods and that differences in temperature under oceans and continents are sufficient to produce convection in the mantle of the earthwith rising convection currents under the mid-ocean ridges and sinkingcurrents under the continent. Theoretically， this convection would carry the continental plates along as though they were on a （conveyer belt） and would provide the forces needed to produce the split that occurs along the ridge.This view may be correct： it has the advantage that the currents are driven by temperature differences that themselves depend on the position ofthe continents.On the other hand， the theory is implausible because convection does not normally occur along lines， and it certainly does not occur long lines broken by frequent offsets or changes in direction， as the ridge is.It has the advantage that the currents are driven by temperature differences that themselves depend on the position of the continents.Such a backoupling， in which the position of the moving plate has an impact on the forces that move it， could produce complicated and varying motionsAlso it is difficult to see how the theory applies to the plate betweenthe Mid-Atlantic Ridge and the ridge in the Indian Ocean.This plate is growing on both sides， and since there is no intermediate trench， the two ridges must be moving apart. It would be odd if the rising convection currents kept exact pace with them.An alternative theory is that the sinking part of the plate， which is denser than the hotter surrounding mantle， pulls the rest of the plate after it. Again it is difficult to see how this applies to the ridge in the South Atlantic， where neither the African nor the American plate has a sinking part.Another possibility is that the sinking plate cools the neighboring mantle and produces convection currents that move the plates. This last theory is attractive because it gives some hope of explaining the enclosed seas， such as the Sea of apan. These seas have a typical oceanic floor， except that the floor is overlaid by several kilometers of sediment. Their floors have probably been sinking for long periods.These seas have a typical oceanic floor， except that the floor is overlaid by several kilometers of sediment. Their floors have probably been sinking for long periods. It seems possible that a sinking current of cooled mantle material on the upper side of the plate might be the cause of such deep basins.The enclosed seas are an important feature of the earth's surface and seriously require explanation because， in addition to the enclosed seas that are developing at present behind island arcs， there are a number of older ones of possibly similar origin， such as the Gulf of Mexico， the Black Sea，and perhaps the North5感谢您的阅读，祝您生活愉快。
华中科技大学英语口语考试素材模板
话题一What is your definition of success?What have you achieved in your life that makes you feel proud?In my submission, success is not to earn a great of money, nor is it to so some so great things. Not to be famous, not to be great, ordinary people also have their own way of success. I think, to make my families, and all the people I love have a happy life, is my own way to be success. Yes, the ancient people said, a man should take the world as his duty. But for me, the most important is to make these people I love happy!As I said, I want to make my love live a happy life. So it' always on the way to success! i want to make myself better and be able to make them feel happy. I remembered once a weekend, my parents are busy working so nobody have time to make a lunch, I tried to make it, but Ididn't learn how to cook before! My little brother and I made an awful lunch after an attempt. I still remember how unsavory it was but the happiness on my parents ' tace is visible. At that moment, the feeling of pride arises spontaneously. I feel I am the most success person in our world. So after that, I tried to learn some cooking skills and I can make some delicious food now.话题二Please describe what is the happiest/mostembarrassing/funniest/scariest thing that has everhappened to you.For me, there is a really scariest thing happened in my life. That was when I had just been in high school for no more than one month! After the military training, we have a long holiday at last. My brother and I went back home together. We are so tired because the intension of the training is so strong! We planned to have a good sleep once we came home. After an hour 's drive and thirty minutes' walk, we finally arrived at our destination. And we found that our parents going out. But, when I was opening the door, he suddenly falls in a faint. I am so scared that I almost fainted too. After realizing what happened, I responded quickly. I dialed a first aid phone and then, call my parents what happened. I put my brother on the sofa to prevent him from catching a cold. And I called his name and asked some questions to see if he was even sober. Just a while, the ambulance arrived. And my parents got back after it. My brother was send to hospital and my heart is still beating fast. I think it 'probably the most scaring thing I have ever experienced.话题三What d o you like about your d ormitory life? What do youdislike? What d o you think can be d one to make your d ormitory a more harmonious community?It has been half a year since we came to our college. And we have already been living in the dorm for several months. I think I like to living in the dorm because I can live with my classmatesand friends. We can study together and play together. But I really don't like the shabby facilities in my dorm. As you know, our dormitory always cut off the water supply, always have a power cut and cut off the internet. And there is no tile in the dorm, it' all cement floors. I can't stand it! We all need to upper bed, I really dislike it! I want to sleep like in my home! And living in the dorm means our parents are not at our side. That' really inconvenient.I think that we all should respect other' habit, seek common ground while reserving differences. We should all endeavor to be more considerate of others. Just like, don't speak loud in the dorm especially when they are having a sleep. And remember; do not unto others as you would not have them do unto you. Doing these means that there would be few conflicts between you and your roommates. If everyone can help each other, respect each one, you dormitory must be a harmonious one!话题四In your eyes, what is the greatest invention of the21st century? Why?There are so many great inventions in this 21st century. The smart phone, artificial intelligence, the virtual reality technology and the augment reality! There is so many inventions in our century. But in my submission, the greatest invention of the 21st century is the nanotechnology. There are so many reasons for why I choose this one to be the greatest.First, the nanotechnology marks the further exploration of the microcosm by human beings. We all know, compared with the micro world; the exploration of the macro world is relatively easy. But the micro world is more representative of the nature of the world.Second,the application of nanotechnology is very extensive. Nanotechnology can be used in various fields, such as medicine, industry, agriculture and so on. In the future, there will be drugs based on nanotechnology to cure people's disease fundamentally. And there will be all kinds of nanobots involved in industrial and agricultural production. It will totally change ourlife!话题五What is your dream job? If you were offered a jobthat was not what you dreamed of but with a decentsalary, would you take it? Why or why not?When I was a little boy, I had so many dream jobs. But now, I am sure what I really want to be. My dream job is to be a chef! Yes, just a chef! No great, no extraordinary. I want to be a chef just because; I want to cook for my families. I always dream about one day, I can make very delicious food for my families and their happiness was on the face. I m sure that at that moment, the feeling of that pride arises spontaneously!But if there is a high salary job, I think I would take it. To be honest, living in our society, every one of us has to have a material well-being life. Just for survive! So I would take the high-salary job in order to make our material life easier. And not to be thechef doesn me a ns I can'cook. I can also learn how to cook delicious food by my studying! At that time, I can also cook for them, and struggle for their happy life!话题六In response to the climate change issue, what d o you think we common peopl e can do to help find out solutions?Yes, it' sure that our daily life has a close relation to the climate change. With the intensification of the greenhouse effect, global warming has seriously affected our daily life. The abrupt change of climate, species extinction, and many natural calamities, all of them is closely related to the greenhouse effect. So it is urgent to improve the greenhouse effect. As an ordinary people, we can do many things!We can start from the small things in life. We should turn the light off once there was no people use it; we ought to turn off the lap after using it. We can ride or work more and drive less, and go to the far place by bus rather than drive our own car. We are supposed to make the garbage classification and make efforts to cyclic utilization. We can do many things in our life to reduce carbon emissions.And we should do more publicity. We should call on our friends and relatives to contribute to reducing the greenhouse effect. Everyone takes part in, the environment will be better soon!话题七What changes do you think have taken place among thedifferent generations in China over the past few d ecad es? What are the reasons for those changes?I think the change is mainly in the ideas. Our generation has totally different ideas from the elder one. For example, our generation always want to be what we want, not limited to others, we always put ourselves in the important position. We will get the job we want, not others. But for the elder generation people, they always take the family in the first position. They work, only to earn for their family, whether you like it or not is the secondary one. And our generation people always look like the international people, while the elder people more like the traditional Chinese people!In my submission,these changes are all based on the rapid development of Chinese society. After the Chinese economic reform, China's economy has grown rapidly. The quality of people's life is increasing. The problem of food and clothing has almost been solved so our generation people care less about the family' finance. And with the integration of China and the international community, our new generation people have a more open vision. So these changes have come into being.话题八What d o you think of the id ol-worshiping behaviorof youngsters around the world? What benefits andnegative influences d o you think this social phenomenonmay bring about?Frankly speaking, I really don 'like this kind of behavior! In my submission, the harm of this kind of behavior is far greater than that of profit. I think as a teenager, the most important work is to study. But the idol-worshiping behavior has bad influence on our study and our health. It 'said that some girls paid her own life for her reasonless action. And this behavior will bring a great burden for the family. Some girls spend a lot of money for their idol, not only abandon her study, but also take some difficulties for their family. But on the other hand, this kind of action has some benefits. In a certain sense, it can promote the economic growth, and it is a way to have a rest.But as a teenager, we should always remember that study is our first duty. We should take study in the most important position. And we should take care of ourselves, don'do anything that is harmful to us. In this way, can we live a happy life!话题九 It is said that peopl e must always be prepared for changes. What is the most difficult change that you have ever had to make? Is there anything that you think you will never change aboutyourself?As we all know, the affairs of the world are inconstant. So we should always prepare for any change! The most difficult change happened in my life was in the high school. Before the high school, I don't take notes in the class; don 'have a preparation or a review after class. And I think I can also get a good grade with fewer efforts. But after the first exam, I am the worst in myclass. I think it is just a bad fortune. But the final exam of the first term, my grade is still slipped. My parents have a talk with me and they told me that I should take more efforts in my study, not just playing computer games. But I really like playing games! I have been thinking for a longtime, so I decided to study harder and play less game. Thanks to my efforts, I got the better and better grade.I think a person 'appearance can be changed, but his heart can t ! So, I believe in my life, I will experiences. A grateful heart makes a happy life. Many teachers teach us these words, but I really understand after I have experienced many things. When I was young, I have a close relationship with one of my classmates. Every time he bought some snacks, he would share some with me. But one day, he didn't! He shared it with the other student. I am really sad with angry! And even I want to break off our friendship! When I get home, I told to my mom. She just smiled to me, I couldn'tunderstand why. She said: You just take it for granted that he should share his snacks with you. But, s not his duty! He has the right to decide who he would share with. If he chose you, you are very happy. But if not, you should not be angry. To maintain a grateful heart, you will have abetter life! After thinking about it, I understand what the meaning is. People always take others kind for granted, but that 's not the case. We should maintain a grateful heart; look at the world with gratitude, the life will be better and better!always try to be a kind person, achanged forever. wise man. A grateful heart and kind mind would not be话题十 To maintaina grateful heart contributes to happiness. Give yourcomments on this statement and illustrate your idea withexamples from your personal。
同济大学考博英语模拟真题及其解析
同济大学考博英语模拟真题及其解析Technically,any substance other than food that alters our bodily or mental functioning is a drug.Many people mistakenly believe the term drug refers only to some sort of medicine or an illegal chemical taken by drug addicts.They don't realize that familiar substances such as alcohol and tobacco are also drugs.This is why the more neutral term substance is now used by many physicians and Geng duo yuan xiao wan zheng kao bo ying yu zhen ti ji qi jie xi qing lian xi quan guo mian fei zi xun dian hua:si ling ling liu liu ba liu jiu qi ba,huo jia zi xun qq:qi qi er liu qi ba wu san qi psychologists. The phrase substance abuse is often used instead of drug abuse to make clear that substances such as alcohol and tobacco can be just as harmfully misused as heroin and cocaine.We live in a society in which the medicinal and social use of substances(drugs)is pervasive:an aspirin to quiet a headache,some wine to be sociable,coffee to get going in the morning,a cigarette for the nerves.When do these socially acceptable and apparently constructive uses of a substance become misuses?First of all,most substances taken in excess will produce negative effects such as poisoning or intense perceptual distortions.Repeated use of a substance can also lead to physical addiction or substance dependence. Dependence is marked first by an increased tolerance,with more and more of the substance required to produce the desired effect,and then by the appearance of unpleasant withdrawal symptoms when the substance is discontinued.Drugs(substances)that affect the central nervous system and alter perception,mood,and behavior are known as psychoactive substances.Psychoactive substances are commonly grouped according to whether they are stimulants,depressants,or hallucinogens. Stimulants initially speed up or activate the central nervous system, whereas depressants slow it down.Hallucinogens have their primary effect on perception,distorting and altering it in a variety of ways including producing hallucinations.These are the substances often called psychedelic(from the Greek word meaning mind-manifestation) because they seemed to radically alter one‘s state of consciousness.59.Substances abuse(line5,paragraph1)is preferable to drug abuse in that________.(A)substances can alter our bodily or mental functioning if illegally used(B)drug abuse is only related to a limited number of drugtakers(C)alcohol and tobacco are as fatal as heroin and cocaine(D)many substances other than heroin or cocaine can also be poisonous60.The word pervasive(line1,paragraph2)might mean________.(A)widespread(B)overwhelming(C)piercing(D) fashionable61.Physical dependence on certain substances results from________.(A)uncontrolled consumption of them over long periods of time(B)exclusive use of them for social purposes(C)quantitative application of them to the treatment of diseases(D)careless employment of them for unpleasant symptoms62.From the last paragraph we can infer that________.(A)stimulants function positively on the mind(B)hallucinogens are in themselves harmful to health(C)depressants are the worst type of psychoactive substances(D)the three types of psychoactive substances are commonly used in groups答案及试题解析59.（D）意为：除海洛因或可卡因外，许多其他物质也是有害的。
华中科技大学考博英语历年试题题型题量综合分析
华中科技大学考博英语历年试题题型题量综合分析导言：考博英语真题的重要性全国各大院校在制定本校英语专业考试大纲时，对英语的考核基本上不指定参考书，考生在备考时往往感到漫无目的，无所适从，所以对各大院校的考博英语历年真题分析则显得尤为重要。
华慧考博英语教研中心在历时8年的教学研究的过程中，总结国内50多所重点院校的考博英语试题的出题特点与规律，认为考生精研各院校的历年试题对考出良好的成绩有非常大的帮助。
考博英语试题的独特性众所周知，英语类的考试，如高考、大学英语四六级、专业四八级考试、研究生入学考试等均由统一的命题组人员统一命制试题，命题组阵容强大，且耗费的人力、物力也不在少数，其题目基本是原创题目。
而考博英语却并非这样，因此，考博英语有其自身的独特性，考博英语的独特性主要表现在其命题方式与题目来源两方面。
首先，从命题方式来看，博士考试中，要求考生达到英语的最低分数线，这一要求就注定了各大考博院校的英语试题的命题方式，各大考博院校不会花费大量的人力、物力及时间原创一套考博英语试题。
并且各大院校为了保证其试题的准确性，一般会选择已经考过的各类相关难度的试题，这样就可以避免出现大量的因个人学术水平方面而引起的错误和争议。
其次，从题目来源看，各大院校的考博英语试题基本来自专四、专八、六级或其它考博院校的原题，极少出现原创题目。
因其题目来源的独特性，我们研究各大院校的考博英语试题就显得非常有必要且益处极大。
如果考生在考前了解了这一情况，且充分重视这个规律，那么获得考博英语高分不是什么难事。
所以考生考前精研考博英语真题是非常有必要的。
考博英语试题的作用考博英语试题的作用主要有三个，即指导、规划与调控作用。
指导作用。
通过研读历年的考博英语试题，考生可以了解该院校的题目类型、题目来源、题目难度等，指导考生在较短的时间内找到正确的复习方法，获得自己满意的成绩。
规划作用。
考生在宏观把握所报考院校的英语试题的出题规律后，结合自身的英语情况，对自己的英语备考做出一个正确且切合实际的复习规划。
华中科技大学同济医学院博士英语样题
Model TestName St. No. ScoreI. Read the following and answer the questions. (10%)2007 JCR Science Edition Journals from: subject categories MEDICINE, GENERAL & INTERNALSorted by:I m pact Fact orJournals 1 - 20 (of 100)[ 1 | 2 | 3 | 4 | 5 ] Page 1 of 5Ranking is based on your journal and sortselections.Rank Abbreviated JournalTitle(linked to journalinformation)ISSNTotalCitesImpactFactorImmediacyIndexArticlesCitedHalf-life1 NEW ENGL J MED0028-4793 186402 52.589 11.962 343 7.02 LANCET0140-6736 135949 28.638 8.636 305 7.73 JAMA-J AM MED ASSOC0098-7484 103620 25.547 7.965 229 6.84 ANN INTERN MED0003-4819 40783 15.516 4.056 162 8.65 ANNU REV MED0066-4219 3829 13.415 2.879 33 6.16 PLOS MED1549-1277 3725 12.601 2.705 166 1.97 BRIT MED J0959-8146 62151 9.723 6.210 210 8.28 ARCH INTERN MED0003-9926 30282 8.391 1.734 278 7.29 CAN MED ASSOC J0820-3946 8324 7.067 3.053 94 6.410 ANN MED0785-3890 3143 5.779 0.593 54 6.11.What is the option of this journal citation report?2.What is the subject category?3.How is the list sorted?4.What is the Impact Factor of New England Journal of Medicine?5.What is the full title of BRIT MED J?II. Read the following and answer the questions. (10%)Web of Science®ResultsSubject Heading=(LIFE SCIENCES BIOMEDICINE) AND Author=(WANG SY) AND Institution=(HUAZHONG UNIV SCI TECHNOL)Timespan=All Years. Databases=IC, SCI-EXPANDED, CCR-EXPANDED [back to 1840], SSCI.1. Zhang ZH, Wang SY, Li Q, et al.Capillary leak syndrome in children with C4A-deficiency undergoing cardiac surgery with cardiopulmonary bypass: a double-blind, randomised controlled studyLANCET 366 (9485): 556-562 AUG 13 2005Times Cited:02. Zhang SH, Wang SY, Yao SLEvidence for development of capillary leak syndrome associated withcardiopulmonary bypass in pediatric patients with the homozygous C4A nullphenotypeANESTHESIOLOGY 100 (6): 1387-1393 JUN 2004Times Cited:43. Zhang SH, Wang SY, Yao SLAntioxidative effect of propofol during cardiopulmonary bypass in adultsACTA PHARMACOLOGICA SINICA 25 (3): 334-340 MAR 2004Times Cited:46.What is the website you can use to find the SCI collection?7.What is the subject heading?8.Where is Wang SY from?9.How many articles of Wang SY are collected by SCI?10.How many times are his articles cited?III. Read the following and answer the questions. (20%)J. Biol. Chem., Vol. 278, Issue 18, 15541-15549, May 2, 2003Induction of Prothrombinase fgl2 by the Nucleocapsid Protein of Virulent Mouse Hepatitis Virus Is Dependent on Host Hepatic Nuclear Factor-4Qin Ning, Sophia Lakatoo, Mingfeng Liu, Weiming Y ang, Zhimo Wang, M. James Phillips, and Gary A. LevyFibrinogen-like protein 2/fibroleukin (Fgl2) plays a pivotal role in the pathogenesis of both experimental and human fulminant hepatic failure. We have reported recently that the nucleocapsid(N) protein from strains of murine hepatitis virus (MHV-3, MHV-A59),which cause massive hepatocellular necrosis but not from strains(MHV-JHM, MHV-2) which do not produce serious liver disease, induces transcription of fgl2. The purpose of the present study was to characterize both viral and host factor(s) necessary for viral induced transcription of fgl2. Mutation of residues Gly-12, Pro-38,Asn-40, Gln-41, and Asn-42 within domain 1 of the N protein of MHV-A59 to their corresponding residues found in MHV-2 abrogated fgl2 transcription, whereas mutation of other N protein domains,including a protein expressed from an internal reading frame (I protein), did not affect fgl2 gene transcription. We then examined the 372 to 306 sequence within the 1.3-kb fgl2promoter region upstream from the transcription start site that was previously identified as necessary for N protein-induced gene transcription.We demonstrated that the 331/325 HNF4 cis-element and its cognate transcription factor, HNF4, are necessary for virus-induced fgl2gene transcription. In uninfected macrophages and macrophages infected with MHV-2, an unidentified protein occupies the HNF4cis-element. Following stimulation with MHV-A59, it was shown by electrophoretic mobility shift assay that HNF4binds the HNF4 cis-element in the fgl2promoter. We further report the unprecedented presence of HNF4in peritoneal macrophages. Collectively, the results of this study define both viral and host factors necessary for induction of fgl2prothrombinase gene transcription in MHV infection and may provide an explanation for the hepatotrophic nature of MHV-induced fulminant hepatic failure.11.How many parts can you divide the abstract into? each part?13.Which sentence is the purpose of the study?14.Which sentence is the conclusion?IV. Read the following and answer the questions. (20%)15.How many parts can you divide the introduction into? each part?17.Which sentence is the purpose of the study?18.Which sentence is the conclusion?V. Read the following and answer the questions. (20%)References and Notes1. State Council AIDS Working Committee Office, U.N. Theme Group on HIV/AIDS in China, A Joint Assessment of HIV/AIDS Prevention, Treatment and Care in China (Beijing, 2004).2. J. Watts, Lancet362, 1983 (2003).3. Ministry of Health of China, UNAIDS, and WHO, 2005 Update on the HIV/AIDS Epidemic and Response in China[Chinese Center for Disease Control and Prevention (China CDC), Beijing, 2006].4. M. J. Rotheram-Borus, P. A. Newman, M. A. Etzel, J. Acquir. Immune Defic. Syndr.25 (suppl.2), S105 (2000).5. The Voluntary HIV-1 Counseling and Testing Efficacy Study Group, Lancet356, 103 (2000).6. S. Allen et al., AIDS17, 733 (2003).7. H. Amaro, A. C. Morrill, J. Dai, J. Health Psychol.10, 287(2005).8. M. E. Bentley et al., AIDS12, 1869 (1998).9. R. Fox, N. J. Odaka, R. Brookmeyer, B. R. Polk, AIDS1, 241 (1987).10. J. A. Inciardi, H. L. Surratt, S. P. Kurtz, J. C. Weaver, AIDS Care17 (suppl. 1), S88 (2005).11. R. R. Robles, T. D. Matos, H. M. Colon, C. A. Marrero, J. C. Reyes, Drugs Soc. (New York) 9,173 (1996).12. A. Erikson et al., Correspondent15, 24 (2006).13.T. Frieden et al., N. Engl. J. Med.353, 2397-2402 (2005).14. R. Bayer, N. Engl. J. Med.334, 1540 (1996).15. L. B. Leveton, H. C. Sox, M. A. Stoto, Eds. HIV and the Blood Supply: An Analysis of CrisisDecision-Making (Institute of Medicine, National Academies Press, Washington, DC, 1995).16. Chinese Ministry of Health, U.N. Theme Group on HIV/AIDS in China, The ThirdConference on HIV/AIDS International Cooperation Projects in China, Kunming, 3 to 4 September 2005.17. UNAIDS-WHO, "Policy statement on HIV testing"(www.who.int/entity/rpc/research_ethics/hivtestingpolicy_en_pdf.pdf).18. Ministry of Health Expert Consultation Committee, "Report on HIV screening among keypopulations in Henan province" (Ministry of Health, Beijing, 2005).19. Ministry of Health Expert Consultation Committee, "Report on HIV screening among keypopulations in Yunnan Province" (Ministry of Health, Beijing, 2005).20. HIV-positive mothers are given the options of abortion or ART perinatally, cesarean delivery(where available), and free formula milk for 12 months.21. State Council Regulations on AIDS Prevention and Treatment, Articles 3, 10, 39, 41, 55, 56.22. The Infectious Diseases Control Act of the People's Republic of China, Articles 12, 16, 68, 69.We thank S. Korenman, Associate Dean for Ethics at the UCLA School of Medicine, for reviewing this manuscript, W. W. Cao for review of relevant publications, and W. Aft for editorial assistance.19.What kind of the reference source does the first reference belong to?20.What kind of the reference source does the second reference belong to?21.What kind of the reference source does Reference 15 belong to?22.What kind of the reference source does Item 20 belong to?VI. Read the following and answer the questions. (10%)SCI Impact Factor 1.677Acta Pharmacologica Sinica Information For Authors GENERAL1 Acta Pharmacologica Sinica, published monthly in English, is the official journal of the Chinese Pharmacological Society and Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences. Acta Pharmacologica Sinica is listed in Biological Abstracts, Chemical Abstracts, CSA Medical Biotechnology, CSA Bioengineering, CSA Neuroscience, Current Contents/Life Sciences, Excerpta Medica, FSTA, Global Health, IndexCopernicus, Index Medicus, Kagaku Gijutsu Bunken Sokuho, MEDLINE, Рефератнвныйжурнап, Research Alert, Science Citation Index, SciSearch, Scopus, Tropical Diseases Bulletin, and many other abstracting and indexing services.Acta Pharmacologica Sinica welcomes current Original articles on all aspects of the life sciences and related areas, both experimental and clinical, from any part of the world. Reviews based primarily on authors?own research of internationally important topics are also welcome. Manuscripts should be prepared in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writing and Editing for Biomedical Publication" as presented at /.2 Prior or duplicate publications are not accepted. All manuscripts, especially data, must not be published or submitted for publication elsewhere. English translations of published articles are not acceptable. The authors should make a full statement on submission about all submissions and previous reports that might be regarded as redundant or duplicate publications of the same or very similar work.The source of financial grants and other funding must be acknowledged, including a frank declaration of the authors' industrial links and affiliations. The contribution of colleagues or institutions should also be acknowledged.…23.What is the SCI Impact Factor of Acta Pharmacological Sinica?24.What kinds of original article are welcomed by Acta Pharmacological Sinica?25.What is the website presenting the "Uniform Requirements for Manuscripts Submitted toBiomedical Journals: Writing and Editing for Biomedical Publication"?26.Does Acta Pharmacological Sinica accept English translations of published articles?27.What must be acknowledged if an article is accepted to be published in Acta PharmacologicalSinica?。
同济大学博士研究生入学英语考试样题
同济大学博士研究生入学英语考试样题I V ocabulary （10%）For each of the following sentences there are four choices. Choose the best one to complete the sentence.1. The directions were so ____ that it was impossible to complete the assignment.A) ingenious B) ambitious C) notorious D) ambiguous2. Our ________ host always enjoys having friends to share his Lucullan suppers.A) cursive B)martial C) fractious D) convivial3. Recently a number of cases have been reported of young children ____a violent act previously seen on television.A) modifying B) stimulating C) accelerating D) duplicating4. This kind of material can _____heat and moisture.A) delete B) compel C) repel D) constrain5. The damage to his car was ____; therefore, he could repair it himself.A) considerable B) appreciable C) negligible D) invisible6. The ____of a cultural phenomenon is usually a logical consequence of some physical aspect in the life style of the people.A) implementation B) expedition C) demonstration D) manifestation7. One of the responsibilities of the Coast guard is to make sure that all ships _______ follow traffic rules in busy harbors.A) cautiously B) dutifully C) faithfully D) skillfully8. The Eskimo is perhaps one of the most trusting and considerate of all Indians but seems to be _______ the welfare of his animals.A) critical about B) indignant at C) indifferent to D) subject to9. The chairman of the board _______ on me the unpleasant job of dismissing good workers the firm can no longer afford to employ.A) compelled B) posed C) pressed D) tempted10. Using extremely different decorating schemes in adjoining rooms may result in _______ and lack of unity in style.A) conflict B) confrontation C) disturbance D) disharmony11. Corrupt politicians who condone the activities of the gamblers are equally _______.A) cryptic B)esoteric C)culpable D)occult12. I don’t know the details for I just gave your manuscript only a(n) _______ gl ance.A) cursory B)cumbrous C)onerous D)obscure13.the Red Cross society helped _________ families to survive the war in the Persian Gulf.A) demure B)destitute C)assiduous D)sedate14. the man felt ________ when the girl turned down his proposal of marriage.A) despondent B) fabulous C)dilapidated D)fortuitous15. the boy gave a ______ look at his classmate’s test paper when the teacher turned.A) frivolous B)furtive C)frenetic D)frigid16. Rubber boots are ___________ to water.A) imperious B)impetuous C)impervious D)impeccable17. Missiles were mounted at various points to _______ the enemy aircrafts.A) integrate B)jeopardize C)intercept D)interrogate18. Being careless, she had her arm _____ by the barbed wire.A) lacerated B)lamented C)juggled D)bemoaned19. The wrestler’s _______ maneuvers made it difficult for his opponent to obtain a hold.A) hermetic B)protean C)titanic D)procrustean20. Psychoanalysis can help a patient recall long-forgotten experiences lost in the ______ recess of his mind.A) labyrinthine B)chimerical C)iridescent D)mercurialII Reading Comprehension (50%)Passage 1There is widespread belief that the emergence of giant industries has been accomplished by an equivalent surge in industrial research. A recent study of important inventions made since the turn of the century reveals that more than half were the product of individual invent-ors working alone, independent of organized industrial research. While industrial laboratories contributed such important products as nylon and transistors, independent inventors developed air conditioning, the automatic transmission, the jet engine, the helicopterminsulin, and streptomycin. Still other inventions, such as stainless steel, television, silicons, and plexiglass were developed through the combined efforts of individuals and laboratory teams.Despite these findings, we are urged to support monopoly power on the grounds that such power creates an environment supportive of innovation. We are told that the independent inventor, along with the small firm, cannot afford to undertake the important research needed to improve our standard of living while protecting our diminishing resources; that only the prodigious assets of the giant corporation or conglomerate can afford the kind of expenditures that can produce the technological advances vital to economic progress. But when we examine expenditures for research, we find that of the more than $ 35 billion spent each year in this country, almost two-thirds is spent by the federal government. More than half of this government expenditure is funneled into military research and product development, accounting for the enormous increase in spending in such industries as nuclear energy, aircraft, missiles, and electronics. There are those who consider it questionable that these defense-linked research projects will account for an improvement in the standard of living or, alternately, do much to protect our diminishing resources. Recent history has demonstrated that we may have to alter our longstanding conception of the process actuated by competition. The price variable, once perceived as the dominant aspect of the competitive process is now subordinate to the competition of the new product, the new business structure, and the new technology. While it can be assumed that in a highly competitive industry not dominated by a single corporation, investment in innovation--a risky and expensive budget item--might meet resistance from management and stockholders who might be more concerned with cost-cutting, efficient organization, and large advertising budgets, it would be an egregious error to assume that the monopolistic producer should be equated with bountiful expenditures for research. Large-scale enterprises tend to operate more comfortably in stable and secure circumstances, and their managerial bureaucracies tend to promote the status quo and resist the threat implicit in change. Furthermore, the firm with a small share of the market will aggressively pursue new techniques and different products, since with little vested interest in capital equipment or plant it is not deterred from in-vestment in innovation. In some cases, where inter-industrycompetition is reduced or even entirely eliminated, the industrial giants may seek to avoid capital loss resulting from obsolescence by deliberately obstructing technological progress.The conglomerates are not, however, completely exempt from strong competitive pressures; there are instances in which they, too, must compete, as against another industrial Goliath, and then their weapons may include large expenditures for innovation.16. According to the passage, important inventions of the twentieth century ________.A. are not necessarily produced as a result of governmental support for military weapons research and development.B. came primarily from the huge laboratories of monopoly industries.C. were produced at least as frequently by independent inventors as by research teams.D. have greater impact on smaller firms than on conglomerates.17. It is the author"s belief, as expressed or implied in the passage, that________.A. monopoly power creates an environment supportive of innovation.B. governmental protection for military research will do much to protect our dwindling resources.C. industrial giants, with their managerial bureaucracies, respond more quickly to technological change.D. firms with a small share of the market will aggressively pursue innovations because they are not locked into old capital equipment.18. Management and stockholders might be deeply concerned with cost cutting rather than innovation if _______.A. their company is faced with strong competition in a field not dominated by one of the industrial giants.B. they are very stable and secure and hold a monopoly position in their industry.C. they are part of the military-industrial complex and are the recipients of federal funds for product development.D. they have produced some of the important inventions of this century.19. Which of the following statements is neither expressed nor implied in the passage?A. Important inventions have been produced, in the past, by individuals as well as by corporate teams.B. The federal government"s research funds are funneled into pure research as well as military research.C. The development of the automatic transmission is not credited to organized industrial research.D. Industrial giants may deliberately suppress innovations to avoid capital loss resulting from obsolescence.20. The author"s purpose in this passage is to____.A. advocate an increase in governmental support of organized industrial research.B. point out a common misconception about the relationship between the extent of industrial research and the growth of monopolistic power in industry.C. describe the inadequacies of small firms in dealing with the important matter of research and innovation.D. show that America"s strength depends upon individual ingenuity and resourcefulness.III Translation from English into Chinese (20%)Three passions, simple but overwhelmingly strong, have governed my life: the longing for love, the search for knowledge, and unbearable pity for the suffering of mankind. These passions, like great winds, have blown me hither and thither, in a wayward course, over a deep ocean of anguish, reaching to the verge of despair.I have sought love, first, because it brings ecstasy---ecstasy so great that I would often have sacrificed all the rest of life for a few hours of this joy. I have sought it, next, because it relieves loneliness that terrible loneliness in which one shivering consciousness looks over the rim of the world into the cold unfathomable lifeless abyss. I have sought it, finally, because in the union of love I have seen, in a mystic miniature, the prefiguring vision of the heaven that saints and poets have imagined. This is what I sought, and though it might seem too good for human life, this is what at last I have found.With equal passion I have sought knowledge. I have wished to understand the hearts of men. I have wished to know why the stars shine. A little of this, but not much, I have achieved.Love and knowledge, so far as they were possible, led upward reward the heavens（这句话似乎不完整）. But always pity brought me back to earth. Echoes of cries of pain reverberated in my heart. Children in famine, victims tortured by oppressors, helpless old people a haled burden to their sons, and the whole world of loneliness, poverty, and pain make a mockery of what human life should be. I long to alleviate the evil, but I cannot, and I too suffer.This has been my life. I have found it worth living, and I would gladly live it again if the chance were offered to me.有三种简单却强烈的情感支配着我的生活，它们分别是：对爱的渴望，对知识的探求，以及对人类的苦难不可抑制的怜悯。
全国医学博士英语考试 作文模板
全国医学博士英语考试作文模板IntroductionThe National Medical Doctoral English Exam is an important assessment for medical professionals aiming to become doctors in China. This exam tests candidates' English proficiency, as well as their understanding of medical terminology and practices. In this article, we will discuss a sample essay template that can be used to prepare for the writing section of the exam.Essay StructureIntroduction: Introduce the topic and provide a brief overview of the main points that will be discussed in the essay.Body Paragraph 1: Discuss the first main point in detail, providing examples and explanations to support your argument.Body Paragraph 2: Discuss the second main point in detail, again providing examples and explanations to support your argument.Body Paragraph 3: Discuss the third main point in detail, providing examples and explanations to support your argument.Conclusion: Summarize the main points discussed in the essay and provide a final thought or recommendation.Sample Essay TemplateIntroductionMedical professionals play a crucial role in society by providing healthcare services to those in need. In order to excel in this field, it is important for doctors to have a strong command of the English language. The National Medical Doctoral English Exam is designed to assess candidates' English proficiency, as well as their knowledge of medical terminology and practices.Body Paragraph 1One of the main reasons why English proficiency is important for medical professionals is that it allows them to communicate effectively with patients from diverse backgrounds. In a multicultural society like China, doctors must be able to speak English fluently in order to provide the best possible care to their patients. For example, a doctor who can communicate with a foreign patient in their native language is more likely to establish trust and build a rapport with them.Body Paragraph 2Additionally, English proficiency is essential for medical professionals who wish to pursue further studies or research opportunities abroad. Many prestigious universities and researchinstitutions require candidates to demonstrate a high level of English proficiency in order to be considered for admission. By excelling in the National Medical Doctoral English Exam, candidates can improve their chances of being accepted into these programs and further their career in the medical field.Body Paragraph 3Lastly, English proficiency is important for medical professionals who wish to stay updated on the latest developments in the field. Many medical journals and research papers are published in English, and doctors who can read and understand these publications will be better equipped to provide evidence-based care to their patients. By improving their English proficiency, medical professionals can enhance their knowledge and skills, ultimately improving the quality of care they provide.ConclusionIn conclusion, the National Medical Doctoral English Exam is an important assessment for medical professionals aiming to become doctors in China. By excelling in this exam, candidates can improve their English proficiency, as well as their understanding of medical terminology and practices. This will not only benefit their career in the medical field but also improve the quality of care they provide to their patients.。
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I：根据JCR分类的期刊的影响因子、全称相关的问题，练习使用JCR和作者查询；5%--5道题II：根据Web of Science搜索作者+单位+领域得到的文章及被引次数的问题；5%--5道题III：一篇Title+Abstract的划分几部分，每部分分别到哪里相关的问题；P20810%--5道题Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. AbstractWithout an approved vaccine or treatments,Ebola outbreak management has been limited to palliative care and barrier methods to prevent transmission.These approaches,however,have yet to end the2014outbreak of Ebola after its prolonged presence in West Africa.／Here we show that a combination of monoclonal antibodies(ZMapp),optimized from two previous antibody cocktails,is able to rescue 100%of rhesus macaques when treatment is initiated up to5days post-challenge.／High fever,viraemia and abnormalities in blood count and blood chemistry were evident in many animals before ZMapp intervention.Advanced disease,as indicated by elevated liver enzymes,mucosal haemorrhages and generalized petechia could be reversed,leading to full recovery.ELISA and neutralizing antibody assays indicate that ZMapp is cross-reactive with the Guinean variant of Ebola.／ZMapp exceeds the efficacy of any other therapeutics described so far,and results warrant further development of this cocktail for clinical use.Questions：11.Among the eight types of titles,which type does this title belong to?A:noun phrase and prepositional phrase.12.How many parts can you divide the abstract into Name each part?A:Four parts.1.Background,2.objective,3.Methods and Reults,4.Conclusion.13.What is the objective of the study?A:Here we show that…up to5days post-challenge.14.What are the results?A:Advanced disease…with the Guinean variant of Ebola.15.In the sentence,”Advanced disease,as indicated by elevated liver enzymes,mucosal haemorrhages and generalized petechia could be reversed,leading to full recovery.”Please translate the term“generalized petechia”into Chinese?A:全身瘀斑IV：最后一次课，无PPT一篇Introduction+Reference Title：P21720%--10道题IntroductionEbola virus(EBOV)infections cause severe illness in humans,and after an incubation period of3to21days,patients initially present with general flu-like symptoms beforea rapid progression to advanced disease characterized by hemorrhage,multi-organ failure and a shock-like syndrome1.In the spring of2014,a new EBOV variant emerged in the West African country of Guinea2,an area in which EBOV has not been previously reported.Despite a sustained international response from local and international authorities including the Ministry of Health(MOH),World Health Organization(WHO)and Médecins Sans Frontières(MSF)since March2014,the outbreak has yet to be brought to an end after five months.As of15th August2014, there are2127total cases and1145deaths spanning Guinea,Sierra Leone,Liberia and Nigeria3.So far,this outbreak has set the record for the largest number of cases and fatalities,in addition to geographical spread4.Controlling an EBOV outbreak of this magnitude has proven to be a challenge and the outbreak is predicted to last for at least several more months5.In the absence of licensed vaccines and therapeutics against EBOV,there is little that can be done for infected patients outside of supportive care,which includes fluid replenishment,administration of antivirals,and management of secondary symptoms6,7.With overburdened personnel,and strained local and international resources,experimental treatment options cannot be considered for compassionate use in an orderly fashion at the moment.However,moving promising strategies forward through the regulatory process of clinical development has never been more urgent.Over the past decade,several experimental strategies have shown promise in treating EBOV-challenged nonhuman primates(NHPs)after infection.These include recombinant human activated protein C(rhAPC)8,recombinant nematode anticoagulant protein c2(rNAPc2)9,small interfering RNA(siRNA)10,positively-charged phosphorodiamidate morpholino oligomers(PMO plus)11,the vesicular stomatitis virus vaccine(VSVΔG-EBOVGP)12,as well as the monoclonal antibody(mAb)cocktails MB-003(consisting of human or human-mouse chimeric mAbs c13C6,h13F6and c6D8)13and ZMAb(consisting of murine mAbs m1H3,m2G4and m4G7)14.Of these,only the antibody-based candidates have demonstrated substantial benefits in NHPs when administered greater than24hours past EBOV exposure.Follow-up studies have shown that MB-003is partially efficacious when administered therapeutically after the detection of two disease“triggers”15,and ZMAb combined with an adenovirus-based adjuvant provides full protection in rhesus macaques when given up to72hours after infection16.The current objective is to develop a therapeutic superior to both MB-003and ZMAb, which could be utilized for outbreak patients,primary health-care providers,as well as high-containment laboratory workers in the future.This study aims to first identify an optimized antibody combination derived from MB-003and ZMAb components, before determining the therapeutic limit of this mAb cocktail in a subsequent experiment.In order to extend the antibody half-life in humans and to facilitate clinical acceptance,the individual murine antibodies in ZMAb were first chimerized with human constant regions(cZMAb).The cZMAb components were then producedin Nicotiana benthamiana17,using the large-scale,cGMP-compatible Rapid Antibody Manufacturing Platform(RAMP)and magnICON vectors that currently also manufactures the individual components of cocktail MB-003,before efficacy testing in animals.References1.Bausch DG,Sprecher AG,Jeffs B,Boumandouki P.Treatment of Marburg and Ebola hemorrhagic fevers:a strategy for testing new drugs and vaccines under outbreak conditions.Antiviral Res.2008;78:150–161.doi:10.1016/j.antiviral.2008.01.152.[PubMed][Cross Ref]2.Baize S,et al.Emergence of Zaire Ebola Virus Disease in Guinea-Preliminary Report.N Engl J Med.2014doi:10.1056/NEJMoa1404505.[PubMed][Cross Ref]3.WHO.int.WHO-Ebola virus disease(EVD)2014<http://www.who.int/csr/don/archive/disease/ebola/en/>..Chronology of Ebola Hemorrhagic FeverOutbreaks.2014</vhf/ebola/resources/outbreak-table.html>.5.Reliefweb.int.W.African Ebola epidemic‘likely to last months’:UN.2014<http://reliefweb.int/report/guinea/w-african-ebola-epidemic-likely-last-mo nths-un>.6.Clark DV,Jahrling PB,Lawler JV.Clinical management of filovirus-infected patients.Viruses.2012;4:1668–1686.doi:10.3390/v4091668.[PMC freearticle][PubMed][Cross Ref]7.Guimard Y,et anization of patient care during the Ebola hemorrhagic fever epidemic in Kikwit,Democratic Republic of the Congo,1995.J InfectDis.1999;179(Suppl1):S268–273.doi:10.1086/514315.[PubMed][Cross Ref]8.Hensley LE,et al.Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever.J Infect Dis.2007;196(Suppl2):S390–399.doi: 10.1086/520598.[PubMed][Cross Ref]9.Geisbert TW,et al.Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor:a study in rhesus ncet.2003;362:1953–1958. doi:10.1016/S0140-6736(03)15012-X.[PubMed][Cross Ref]10.Geisbert TW,et al.Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference:a proof-of-conceptncet.2010;375:1896–1905.doi:10.1016/S0140-6736(10)60357-1.[PubMed][Cross Ref]Questions:16.What is the difference between abstract and introduction?A:There are no references in the abstract and no results in introduction.17.How many parts can you divide the introduction into?Name each part?A:Four Parts.Background,Conclusion,Objective,Method18.What problem is posed on this article?A:The current objective is to develop a therapeutic superior to both MB-003and ZMAb,which could be utilized for outbreak patients,primary health-care providers, as well as high-containment laboratory workers in the future.19.In the first paragragh,what does“supportive care”refer to?A:It includes fluid replenishment,administration of antivirals,and management of secondary symptoms20.What style of referencing system does it belong to?A:Citation order system.21.How many authors are listed in item1?A:Four.22.Where is the article published in Item2?A:New England Journal of Medicine.23.What kind of the reference source does item3belong to?24.What type does the title belong to in item10?A:Title and subtitle25.Please translate the Chinese title“肝素疗法的前瞻性随机研究：into English by using the same method as Item10.A:Heparin therapy:Prospective randomized studyVI：Journal Instruction for authors：10%--11道题General InformationJAMA Internal Medicine is an international peer-reviewed journal providing innovative and clinically relevant research for practitioners in general internal medicine and internal medicine subspecialities. The Editor of JAMA Internal Medicine is Rita F.Redberg,MD,MSc,University of California San Francisco School of Medicine,San Francisco,California.The journal is published online every Monday and in print each month.Authorship Criteria and Conditions and Authorship FormEach author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content.One or more of the authors should take responsibility for the integrity of the work as a whole,from inception to published article.1,2According to the guidelines of the International Committee of Medical Journal Editors(ICMJE),as revised in2013,2authorship credit should be based on the following4criteria:(1)substantial contributions to conception or design of the work,or the acquisition,analysis,or interpretation of data for the work;and(2)drafting of the work or revising it critically for important intellectual content;and(3)final approval of the version to be published;and(4)agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Each author should be accountable for the parts of the work he or she has done.In addition,each author should be able to identify which coauthors are responsible for specific other parts of the work and should have confidence in the integrity of the contributions of any coauthors.Changes in AuthorshipAuthors should determine the order of authorship among themselves and should settle any disagreements among themselves before submitting their manuscripts.Changes in authorship(ie,order,addition,and deletion of authors)should be discussed and approved by all authors.Any requests for such changes in authorship after initial manuscript submission and before publication should be explained in writing to the editor in a letter or email from all authors.1(pp134-135)Manuscript SubmissionManuscripts should be submitted online via the online manuscript submission and review system.At the time of submission,complete contact information(affiliation,postal/mail address,e-mail address, telephone and fax numbers)for the corresponding author is required.First and last names,e-mail addresses,and institutional affiliations of all coauthors are also required.Manuscripts submitted through the online system should not also be submitted by mail or e-mail.After the manuscript is submitted,the corresponding author will receive an acknowledgment confirming receipt and a manuscript number.Authors will be able to track the status of their manuscripts via the online system. After manuscript submission,all authors of Letters to the Editor and Invited Commentaries will be sent an Authorship Form to complete and submit(see sample Authorship Form).All authors of all other manuscripts will receive an Authorship Form at the time of request for/receipt of a revision to their manuscript.See Manuscript Checklist,Manuscript Preparation and Submission Requirements,1,2and other details in these instructions for additional requirements.Manuscript StyleManuscripts should be prepared in accordance with the AMA Manual of Style,10th edition,1and/or the ICMJE Recommendations for the Conduct,Reporting,Editing,and Publication of Scholarly Work in Medical Journals.TitleTitles should be concise,specific,and informative and should contain the key points of the work.1(p8) Please limit the length of titles to150characters for reports of research and other major articles and 100characters for Editorials,Viewpoints,Commentaries,and Letters.For scientific manuscripts, overly general titles are not desirable and questions and declarative sentences should be avoided.For reports of clinical trials,meta-analyses,and systematic reviews,include the type of study as a subtitle (eg,A Randomized Clinical Trial,A Meta-analysis,A Systematic Review).For reports of other types of research,do not include study type or design in the title or subtitleReferencesAuthors are responsible for the accuracy and completeness of the references and for their correct text citation.Cite all references in the text or tables.Number references in the order they appear in the text;do not alphabetize.In text,tables,and legends,identify references with superscript arabic numerals.When listing references,follow AMA style1(pp39-79)and abbreviate names of journals according to the journals list in PubMed.List all authors and/or editors up to6;if more than6,list the first3followed by“et al.”Note:Journal references should include the issue number in parentheses after the volume number.Examples of reference style:1.Garbutt JM,Banister C,Spitznagel E,Piccirillo JF.Amoxicillin for acute rhinosinusitis:a randomized controlled trial.JAMA.2012;307(7):685-692.2.Centers for Medicare&Medicaid Services.CMS proposals to implement certain disclosure provisions of the Affordable Care Act./apps/media/press/factsheet.asp?Counter=4221.Accessed January30,2012.3.McPhee SJ,Winker MA,Rabow MW,Pantilat SZ,Markowitz AJ,eds.Care at the Close of Life: Evidence and Experience.New York,NY:McGraw Hill Medical;2011.Questions:25.What kinds of articles does JAMA provide?A:They provide innovative and clinically relevant research for practitioners in general internal medicine and internal medicine subspecialities.26.How many criteria are the authorship credit based on?A:There are4criteria.27.What is required if there are changes in authorship?A:Any requests for such changes in authorship after initial manuscript submission and before publication should be explained in writing to the editor in a letter or email from all authors28.Can authors submit their articles via mail or e-mail?A:No29.How do authors know the status of their manuscript?A:Authors will be able to track the status of their manuscripts via the online system30.What is the requirement for the title of reports of research and other major articles?A:Please limit the length of titles to150characters for reports of research and other major articles 31.Structured abstract can be further divided into two kinds.What are they?A:The first kind is divided into five parts:Background,Objective,Methods,Results and Conclusion and the other one is divided into four parts:Objective,Methods,Results and Conclusion.32.In test,tables,and legends,how are the references identified?A:In text,tables,and legends,identify references with superscript arabic numerals.33.If the authors are more than six,how to list the authors’name?A:if more than6,list the first3followed by“et al.”34.In reference Item3,what is“Care at the Close of Life:Evidence and Experience”?A:The name of the cited book.35.In reference Item3,NY:McGraw Hill Medical is publisher.。