肺癌课件英文
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肺癌-优秀医学PPT课件
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侵蚀肋骨
周围型肺癌伴胸椎转移：左肺下野见一较大肿块影，密度均匀，边缘 模糊，第四胸椎骨密度减低，椎弓根显示不清。
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痰细胞学检查
鳞癌 小细胞癌
细支气管肺泡癌是肺腺癌的另一类型。这里是肺实变多病灶变异的粗略外观大多数右上肺叶呈现黑-白色到灰色外观。
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支气管肺癌(肺泡细胞型腺癌)
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大细胞型Large cell carcinoma
甚少见 半数起源于大支气管，细胞大胞浆丰富胞核形态多样，细胞排列不规则，分化程度低。 预后很差。 常发生脑转移后才被发现。
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周围型肺癌：右肺下叶背段见一球形肿块影；呈分叶状
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左肺上叶周围型肺癌 ：上叶尖后段见一较大肿块影， 密度均匀，边缘不规则，可见小毛刺。
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周围型肺癌：
肿瘤中心部分液化坏死，呈厚壁偏心空洞，内壁凹凸不平。
右肺下叶周围型肺癌：下叶背段见一较大肿块， 内可见一偏心小空洞伴有液平。
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血行转移 Hematogenous metastasis
是肺癌的晚期表现，病人预后差。 腺癌，小细胞癌血行转移较鳞癌更为常见。 癌细胞—肺V—左心大循环—全身（肝、骨骼、脑、肾上腺多见）。
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五、临床表现 CLINICAL SITUATION
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肺癌症状取决于发生部位、大小、是否压迫临近器官及有无转移。早期可无症状，而在X线体检时发现。中央型出现症状早。周围型较晚。
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杵状指趾和肥大性骨关节病
前者：发生快、疼痛剧烈、甲床周围出现红晕为特点。 后者：以长骨疼痛、骨膜增生、新骨形成或关节疼痛常同时伴发，多见于鳞癌。手术切除肺癌后症状立即减轻或消失。肿瘤复发又可出现。
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侵蚀肋骨
周围型肺癌伴胸椎转移：左肺下野见一较大肿块影，密度均匀，边缘 模糊，第四胸椎骨密度减低，椎弓根显示不清。
*
痰细胞学检查
鳞癌 小细胞癌
细支气管肺泡癌是肺腺癌的另一类型。这里是肺实变多病灶变异的粗略外观大多数右上肺叶呈现黑-白色到灰色外观。
*
支气管肺癌(肺泡细胞型腺癌)
*
大细胞型Large cell carcinoma
甚少见 半数起源于大支气管，细胞大胞浆丰富胞核形态多样，细胞排列不规则，分化程度低。 预后很差。 常发生脑转移后才被发现。
*
周围型肺癌：右肺下叶背段见一球形肿块影；呈分叶状
*
左肺上叶周围型肺癌 ：上叶尖后段见一较大肿块影， 密度均匀，边缘不规则，可见小毛刺。
*
周围型肺癌：
肿瘤中心部分液化坏死，呈厚壁偏心空洞，内壁凹凸不平。
右肺下叶周围型肺癌：下叶背段见一较大肿块， 内可见一偏心小空洞伴有液平。
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*
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血行转移 Hematogenous metastasis
是肺癌的晚期表现，病人预后差。 腺癌，小细胞癌血行转移较鳞癌更为常见。 癌细胞—肺V—左心大循环—全身（肝、骨骼、脑、肾上腺多见）。
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五、临床表现 CLINICAL SITUATION
*
肺癌症状取决于发生部位、大小、是否压迫临近器官及有无转移。早期可无症状，而在X线体检时发现。中央型出现症状早。周围型较晚。
*
*
杵状指趾和肥大性骨关节病
前者：发生快、疼痛剧烈、甲床周围出现红晕为特点。 后者：以长骨疼痛、骨膜增生、新骨形成或关节疼痛常同时伴发，多见于鳞癌。手术切除肺癌后症状立即减轻或消失。肿瘤复发又可出现。
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肺癌英文PPT演示幻灯片
cell carcinoma).
7
Pathology And Classification
According to the different principles of management,it is divided into two types.
SCLC:small cell lung carcinoma. NSCLC:non small cell lung carcinoma.
5
Pathology And Classification
1. According to the position of tumor arising from ,it can be divided into two types .
Central type:Tumor arises from main bronchus, lobar and segmental bronchus . Peripheral type : Tumor arises beyond segmental bronchus .
11
Clinical Features
(4).Horner’s syndrome.It is caused by invading the cervical sympathetic ganglia on the involved side the pupil is small ptosis of the up eyelids,retraction of the eyeball and no sweat of the face.
(5)Cardiac effusion
12
Passive smoking is also a carcinogen factor.
7
Pathology And Classification
According to the different principles of management,it is divided into two types.
SCLC:small cell lung carcinoma. NSCLC:non small cell lung carcinoma.
5
Pathology And Classification
1. According to the position of tumor arising from ,it can be divided into two types .
Central type:Tumor arises from main bronchus, lobar and segmental bronchus . Peripheral type : Tumor arises beyond segmental bronchus .
11
Clinical Features
(4).Horner’s syndrome.It is caused by invading the cervical sympathetic ganglia on the involved side the pupil is small ptosis of the up eyelids,retraction of the eyeball and no sweat of the face.
(5)Cardiac effusion
12
Passive smoking is also a carcinogen factor.
肺癌PPT课件
显示Pancoast瘤与毗邻血管、臂丛神经的关 系，在矢状与冠状位扫描优于横轴位CT
• 痰细胞学检查
• 阳性率为60%左有，高者达80%以 上。其中，约2/3的病变位于中央， 在支气管镜能够观察到的范围内
• 胸水细胞学检查
• 与 痰一样，阴性结果并不重要，但 肯定的阳性发现却非常重要
• 常用三种方法 •灌注扫描 •检查肺癌的转移灶 •亲肿瘤扫描 •直接提示肺部肿瘤 •吸入扫描 •间接提示肺部肿瘤
FDG-PET在肺部肿瘤诊治中的应用：
确定肺内病变的存在及性质 对肺癌患者进行临床TNM分期。 发现常规检查未发现的亚临床转移病灶。 判断肿瘤对治疗的反应，指导治疗方案。 肿瘤局部复发的早期诊断。
纤维支气管镜检查
• 纤支镜检查除观察病灶外，主要目的在于钳 取组织进行病理检查以明确诊断 ;其对中央型 肺癌阳性率较高
• 胸内转移症状
• 胸水：血性胸水一般系肿瘤直接侵犯胸膜所致， 提示预后不佳
• 纵隔受累
• 压迫上腔静脉，引起上腔静脉综合征 • 压迫食管致吞咽困难 • 累及一侧喉返神经致声音嘶哑 • 肺尖部的肿瘤---Pancoast瘤，常常出现胸廓上口受累
的症状
*Pancoast瘤
支气管源癌，鳞癌为主，少数为小细胞癌。位 于肺尖部，常出现胸廓上口受累的症状，表现 为:1)胸腔上口软组织受累，合并邻近骨质破坏 和局部性疼痛;2)臂丛神经受累，引起患侧上肢、 手部疼痛，手部肌肉萎缩;3)支配头颈部同侧的 颈交感神经节受累，引起Horner综合征
某些金属和非金属物质 如铀、铬、镍、铍、氡、砷、锡、 石棉等有致癌作用。其中最重要的是石棉。石棉工人发生 肺癌的危险是普通人的6~10倍
大气污染 可使肺癌的发病率提高2~3倍:肺癌死亡率在城市 高于农村
• 痰细胞学检查
• 阳性率为60%左有，高者达80%以 上。其中，约2/3的病变位于中央， 在支气管镜能够观察到的范围内
• 胸水细胞学检查
• 与 痰一样，阴性结果并不重要，但 肯定的阳性发现却非常重要
• 常用三种方法 •灌注扫描 •检查肺癌的转移灶 •亲肿瘤扫描 •直接提示肺部肿瘤 •吸入扫描 •间接提示肺部肿瘤
FDG-PET在肺部肿瘤诊治中的应用：
确定肺内病变的存在及性质 对肺癌患者进行临床TNM分期。 发现常规检查未发现的亚临床转移病灶。 判断肿瘤对治疗的反应，指导治疗方案。 肿瘤局部复发的早期诊断。
纤维支气管镜检查
• 纤支镜检查除观察病灶外，主要目的在于钳 取组织进行病理检查以明确诊断 ;其对中央型 肺癌阳性率较高
• 胸内转移症状
• 胸水：血性胸水一般系肿瘤直接侵犯胸膜所致， 提示预后不佳
• 纵隔受累
• 压迫上腔静脉，引起上腔静脉综合征 • 压迫食管致吞咽困难 • 累及一侧喉返神经致声音嘶哑 • 肺尖部的肿瘤---Pancoast瘤，常常出现胸廓上口受累
的症状
*Pancoast瘤
支气管源癌，鳞癌为主，少数为小细胞癌。位 于肺尖部，常出现胸廓上口受累的症状，表现 为:1)胸腔上口软组织受累，合并邻近骨质破坏 和局部性疼痛;2)臂丛神经受累，引起患侧上肢、 手部疼痛，手部肌肉萎缩;3)支配头颈部同侧的 颈交感神经节受累，引起Horner综合征
某些金属和非金属物质 如铀、铬、镍、铍、氡、砷、锡、 石棉等有致癌作用。其中最重要的是石棉。石棉工人发生 肺癌的危险是普通人的6~10倍
大气污染 可使肺癌的发病率提高2~3倍:肺癌死亡率在城市 高于农村
2020年肺癌英文.ppt
Incidence and mortality
• Bronchogenic carcinoma has increased remarkable in
incidence and mortality during half of the century and has
become the most frequent visceral malignant diseases of men.The mortality of lung cancer hold the first place among all
Etiology
• 2.Atmospheric pollution.It was found that carcinogenic factor is benzpyrene .
• 3.Occupational factors. • 4Radioactivity in the atmosphere . • 5.Diets and Nutrition. • 6.Chronic irritation. • 7.Genetic factors.
Clinical features
• There are no symptoms of early lung cancer in some patients. • Symptoms caused by lung cancer are non-specific:perhaps an
audible wheeze or a slight cough,symptoms of infection (fever ,purulent sputum) , of obstruction (wheezing,dyspnea), or ulceration of bronchial mucosa (hemoptysis).
讲课肺癌英文演示文稿
• Due to local extension: chest pain,hoarseness,superior vena cava syndrome, horner’s syndrome, dysphagia, pericardial effusion,pleural effusion, diaphragm paralysis
讲课肺癌英文演示 文稿
What is Lung Cancer?
• Begins when cells in the lung grow out of control and form a tumor
Etiology and pathogenesis
• Cigarette smoking • Other factors include air
• According to histologic classification: Small cell lung cancer(SCLC) and Non-small cell
lung cancer(NSCLC). NSCLC includes Squamous cell carcinoma,
• it causes symptoms early in
• areas of scarring is associated with the occurrence of adenocarcinoma.
• Peripheral adenocarcinomas are usually wellcircumscribed, grey-white masses that rarely cavitate.
• Intercellular bridges and cellular pleomorphism
• squamous cell carcinoma usually occurs near the bronchi, the tumor can cause cough (sometimes a cough that is tinged with blood), shortness of breath, wheezing, and pneumonia in the area between the tumor and the edge of the lung
讲课肺癌英文演示 文稿
What is Lung Cancer?
• Begins when cells in the lung grow out of control and form a tumor
Etiology and pathogenesis
• Cigarette smoking • Other factors include air
• According to histologic classification: Small cell lung cancer(SCLC) and Non-small cell
lung cancer(NSCLC). NSCLC includes Squamous cell carcinoma,
• it causes symptoms early in
• areas of scarring is associated with the occurrence of adenocarcinoma.
• Peripheral adenocarcinomas are usually wellcircumscribed, grey-white masses that rarely cavitate.
• Intercellular bridges and cellular pleomorphism
• squamous cell carcinoma usually occurs near the bronchi, the tumor can cause cough (sometimes a cough that is tinged with blood), shortness of breath, wheezing, and pneumonia in the area between the tumor and the edge of the lung
肺癌英文(课堂PPT)
5
Pathology And Classification
1. According to the position of tumor arising from ,it can be divided into two types .
Central type:Tumor arises from main bronchus, lobar and segmental bronchus . Peripheral type : Tumor arises beyond segmental breatures
(4).Horner’s syndrome.It is caused by invading the cervical sympathetic ganglia on the involved side the pupil is small ptosis of the up eyelids,retraction of the eyeball and no sweat of the face.
9
Clinical features
1.Respiratory symptoms.
(1).Cough: (2).Hemoptysis: (3).Dyspnea.: (4).Wheeze or stridor: (5).Chest pain : (6).Fever:
10
Clinical features
cell carcinoma).
7
Pathology And Classification
According to the different principles of management,it is divided into two types.
SCLC:small cell lung carcinoma. NSCLC:non small cell lung carcinoma.
Pathology And Classification
1. According to the position of tumor arising from ,it can be divided into two types .
Central type:Tumor arises from main bronchus, lobar and segmental bronchus . Peripheral type : Tumor arises beyond segmental breatures
(4).Horner’s syndrome.It is caused by invading the cervical sympathetic ganglia on the involved side the pupil is small ptosis of the up eyelids,retraction of the eyeball and no sweat of the face.
9
Clinical features
1.Respiratory symptoms.
(1).Cough: (2).Hemoptysis: (3).Dyspnea.: (4).Wheeze or stridor: (5).Chest pain : (6).Fever:
10
Clinical features
cell carcinoma).
7
Pathology And Classification
According to the different principles of management,it is divided into two types.
SCLC:small cell lung carcinoma. NSCLC:non small cell lung carcinoma.
肺癌研究报告Lung cancer(英文)ppt课件
PPT学习交流
8
Environmental Risk Factors Alcohol
Diet and Body Mass
Non-modifiable Risk Factors Age \Race \Sex
PPT学习交流
9
Types
squamous cell carcinoma,squamous epithelium of the lungs or bronchi
An individual then has a better idea of
the value of different fors that are taken into
account include the person's general
health, medical problems that may affect
Small cell lung carcinoma (SCLC) accounts for approximately 20% of all primary lung cancers
The histologic distinction between nonsmall cell lung cancer and small cell lung cancer is extremely important. There are substantial differences between the two groups in both treatment and prognosis.
PPT学习交流
14
Other symptoms that are
associated with lung
cancer include:
讲课肺癌英文 PPT
• Due to local extension: chest pain,hoarseness,superior vena cava syndrome, horner’s syndrome, dysphagia, pericardial effusion,pleural effusion, diaphragm paralysis
lung cancer(NSCLC). NSCLC includes Squamous cell carcinoma,
large cell carcinoma, adenocarcinoma, adenosquamous carcinoma.
Small cell lung cancer(SCLC)
• It arises from the submucosal glands,located in peripheral airways and alveoli
• Female
large cell carcinoma
• large nuclei,prominent nucleoli,abundant cytoplsma
neuroendocrine cells that are responsible for the production and secretion of specific peptide product.they may related to paraneoplastic syndrome.
• Cells are oval or vaguely spindleshaped ,have scant cytoplasm
大家学习辛苦了，还是要坚持
继续保持安静
Squamous cell carcinoma
• the most frequent form of the tumor(30-50 percent of all cases
lung cancer(NSCLC). NSCLC includes Squamous cell carcinoma,
large cell carcinoma, adenocarcinoma, adenosquamous carcinoma.
Small cell lung cancer(SCLC)
• It arises from the submucosal glands,located in peripheral airways and alveoli
• Female
large cell carcinoma
• large nuclei,prominent nucleoli,abundant cytoplsma
neuroendocrine cells that are responsible for the production and secretion of specific peptide product.they may related to paraneoplastic syndrome.
• Cells are oval or vaguely spindleshaped ,have scant cytoplasm
大家学习辛苦了，还是要坚持
继续保持安静
Squamous cell carcinoma
• the most frequent form of the tumor(30-50 percent of all cases
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★Benzopyrene is the main carcinogen ★The relationship between smoking
and lung cancer risk was related to the type of tobacco, the age at which smoking began, the number of years of smoking, and the amount of smoking
Each cigarette
shortens a
•
smoker's life
by seven
minutes
Etiology
• The association between smoking and squamous cell carcinoma was significantly higher than that of adenocarcinoma
Etiology
4、Ionizing radiation：Large doses of ionizing radiation can cause lung cancer, different radiation effects are different
5、Diet and nutrition： Chronic food deficiencies of vitamin A and β carotene and trace elements (zinc(Zn), selenium(Se)) are prone to lung cancer.
Because vitamin A is an antioxidant.
Etiology
6、Others：
• The risk of lung cancer was significantly correlated with chronic bronchitis and tuberculosis.
Passive smoking for 15 minutes equals active smoking
Etiology
2、Occupational carcinogen:
• Confirmed carcinogens：Chromium, nickel, arsenic, beryllium, asbestos, soot, coal tar, mustard gas, isopropyl oil, dichloromethyl ether and ionizing radiation.
Overview
overview
• Bronchial cancer: lung cancer refers to the cancer originating in the bronchial mucosa or glands
• bronchial glands or alveolar epithelium, lung cancer is actually bronchogenic cancer
• The American cancer society lists tuberculosis as a risk factor for lung cancer.
Etiology
• Recent molecular biology studies have shown that the occurrence of lung cancer is closely related to the of some oncogenes and the of tumor suppressor genes.
Hale Waihona Puke Etiology★Passive smokers have a 50% increased risk of lung cancer
Definition: people who live and work around smokers unconsciously inhaling smoke particles and toxic substances.
Bronchogenic Carcinoma
Learning goals
➢Overview ➢Etiology ➢Classification ➢Clinical Features ➢Examination ➢Diagnosis and differential diagnosis ➢Staging of lung cancer ➢Treatment
• Smoking cessation for 10 years can reduce the incidence of lung cancer by 80 %
• The incidence of lung cancer 15 years after quitting was similar to that of nonsmokers
Globle Incidence of Cance
Etiology
Etiology
1、Smoking
★Smoking is the leading risk factor for lung cancer
other reasons
cigarethes 90%
Etiology
★Smokers are 10 to 13 times more likely to develop lung cancer than nonsmokers
overview
• Both morbidity and mortality rates are increasing significantly
• The incidence and death rate of male lung cancer ranks the first in the world.
Etiology
3、The air pollution：
• Outdoor environmental pollution：Industrial waste gas, highway asphalt, motor vehicle exhaust gas
Eiology
• Indoor environmental pollution：Such as kitchen small environment coal tar, soot,tobacco
and lung cancer risk was related to the type of tobacco, the age at which smoking began, the number of years of smoking, and the amount of smoking
Each cigarette
shortens a
•
smoker's life
by seven
minutes
Etiology
• The association between smoking and squamous cell carcinoma was significantly higher than that of adenocarcinoma
Etiology
4、Ionizing radiation：Large doses of ionizing radiation can cause lung cancer, different radiation effects are different
5、Diet and nutrition： Chronic food deficiencies of vitamin A and β carotene and trace elements (zinc(Zn), selenium(Se)) are prone to lung cancer.
Because vitamin A is an antioxidant.
Etiology
6、Others：
• The risk of lung cancer was significantly correlated with chronic bronchitis and tuberculosis.
Passive smoking for 15 minutes equals active smoking
Etiology
2、Occupational carcinogen:
• Confirmed carcinogens：Chromium, nickel, arsenic, beryllium, asbestos, soot, coal tar, mustard gas, isopropyl oil, dichloromethyl ether and ionizing radiation.
Overview
overview
• Bronchial cancer: lung cancer refers to the cancer originating in the bronchial mucosa or glands
• bronchial glands or alveolar epithelium, lung cancer is actually bronchogenic cancer
• The American cancer society lists tuberculosis as a risk factor for lung cancer.
Etiology
• Recent molecular biology studies have shown that the occurrence of lung cancer is closely related to the of some oncogenes and the of tumor suppressor genes.
Hale Waihona Puke Etiology★Passive smokers have a 50% increased risk of lung cancer
Definition: people who live and work around smokers unconsciously inhaling smoke particles and toxic substances.
Bronchogenic Carcinoma
Learning goals
➢Overview ➢Etiology ➢Classification ➢Clinical Features ➢Examination ➢Diagnosis and differential diagnosis ➢Staging of lung cancer ➢Treatment
• Smoking cessation for 10 years can reduce the incidence of lung cancer by 80 %
• The incidence of lung cancer 15 years after quitting was similar to that of nonsmokers
Globle Incidence of Cance
Etiology
Etiology
1、Smoking
★Smoking is the leading risk factor for lung cancer
other reasons
cigarethes 90%
Etiology
★Smokers are 10 to 13 times more likely to develop lung cancer than nonsmokers
overview
• Both morbidity and mortality rates are increasing significantly
• The incidence and death rate of male lung cancer ranks the first in the world.
Etiology
3、The air pollution：
• Outdoor environmental pollution：Industrial waste gas, highway asphalt, motor vehicle exhaust gas
Eiology
• Indoor environmental pollution：Such as kitchen small environment coal tar, soot,tobacco