这样写英文Email

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写英文邮件的范文(精选5篇)

写英文邮件的范文(精选5篇)

写英文邮件的范文(精选5篇)写英文邮件的范文篇1Dear my friend,I am here writing to your to express my gratitude to you for congratulation.You mentioned how to improve the translation ability. Now I would like to offer you some suggestions.The most important factor to be considered is that you must grasp a largebank of vocabulary, which is the foundation for translation. Secondly, you can try to practice translation everyday. After your translation, you can compare your translation with the given answer. Last but not the least, you must pay very close attention to the difference between the two languages. Differences between laguges must be considered when you are translating.I am looking forward to meeting you in the near future. Then, we can have a talk face to face. I sincerely hope that my suggestions can be constructive to you.Truly yours写英文邮件的范文篇2Directions:Suppose you won a translation contest and your friend, Jack, wrote an email to congratulate you and ask for advice on translation. Write him a reply to1) thank him, and2) give advice.You should write neatly on the ANSWER SHEET.Do notsign your own name at the end of the text. Use “Li Ming” instead.Do notwrite the address.(10 points)写英文邮件的范文篇3Dear Mary,Thanks for your last letter. I'm so glad that you have been able (at last! ) to arrange a holiday in Australia. As I fear I won't be able to meet you at the airport when you arrive, nor will I be able to be home until later in the afternoon, so here are some instructions and suggestions.There is a bus from the airport to the city. It is much cheaper than a cab. Take the bus to the city and ask to get off at Town Hall railway station.To get to my place in the eastern suburbs you have three options. You can either take a cab, a bus or the train. I suggest you take the train, since the airport bus will leave you right at the station. Get off at Cliff Station. From there you can either walk to my place (about ten minutes) or take a taxi. Probably you should take a taxi as you will have luggage.When you arrive at my flat, ring the intercom for Flat 2. My friend Lillian will be at home and she will open the front door for you and let you into my flat.Presumably you will be tired and want to sleep. But if you feel like some exercise after that long flight, you could stroll down to Cooper Park, which is only ten minutes away ? you can see it from the window.Cheers and looking forward to seeing you.Yours sincerely,Annie写英文邮件的范文篇4Dear Jack,I am writing to thank you for your congratulations on mysuccess in the translation contest. In your letter, you told me that you wanted to know how to do well in translation. Here are some pieces of advice.First, you need to grasp the basic grammar knowledge, which enables to you to understand the sentences correctly and translate the original language to the target language properly. Second, a wide range of extensive knowledge in different fields is preferred because the more you know, the easier it is for you to make clear what the passage is talking about.I hope these pieces of information are of great help for your future study and translation.Yours sincerely,Li Ming写英文邮件的范文篇5ear Mr. Seaton,Thank you very much for taking me with you on that splendid outing to London. It was the first time that I had seen the T ower or any of the other famous sights. If I'd gone alone, I couldn't have seen nearly as much, because I wouldn't have known my way about.The weather was splendid on that day, which I thought was rare. I still remember some people told me that in Britain there was weather and no climate. During the same day, it might snow in the morning, rain at noon, shine in the afternoon and be windy before the night falls. So I think I was lucky.I think the river trip was the best thing of all. London really came alive for me as we saw it from the Thames during that wonderful journey down to Greenwich. It was all tremendously exciting - a day that I shall never forget.Thank you for giving me such a great birthday treat.Yours sincerely, Linda Chen。

写英文邮件范文(精选十三篇)

写英文邮件范文(精选十三篇)

写英文邮件范文(精选十三篇)(经典版)编制人:__________________审核人:__________________审批人:__________________编制单位:__________________编制时间:____年____月____日序言下载提示:该文档是本店铺精心编制而成的,希望大家下载后,能够帮助大家解决实际问题。

文档下载后可定制修改,请根据实际需要进行调整和使用,谢谢!并且,本店铺为大家提供各种类型的经典范文,如工作总结、工作计划、合同协议、条据文书、策划方案、句子大全、作文大全、诗词歌赋、教案资料、其他范文等等,想了解不同范文格式和写法,敬请关注!Download tips: This document is carefully compiled by this editor. I hope that after you download it, it can help you solve practical problems. The document can be customized and modified after downloading, please adjust and use it according to actual needs, thank you!Moreover, our store provides various types of classic sample essays for everyone, such as work summaries, work plans, contract agreements, doctrinal documents, planning plans, complete sentences, complete compositions, poems, songs, teaching materials, and other sample essays. If you want to learn about different sample formats and writing methods, please stay tuned!写英文邮件范文(精选十三篇)写英文邮件范文(篇一)Dear Sir,I noticed an ad.In the paper today you said you were looking for people to join your e_pedition team.It sounded as if it might be fun so Im writing to say Id like to come along.About myself: I left school at 16 because I wanted to earn a bit of money.After that I got a few part-time jobs as a waiter,etc.But I didnt stick to any of them for long.Recently Ive been doing a bit of hitch-hiking round Europe so Ive had some e_perience of traveling the hard way which should come in handy on the e_pedition youre planning.By the way,Im a great guitarist so I can keep you all amused round the campfire at night.Let me know when I can call in for a chat about dates and other details, etc.Yours,David Smith写英文邮件范文(篇二)dear sir or madam:thank you for your inquiry dated 25 march.we are always pleased to hear from a valued company.i regret to say that we cannot agree to your request for technical information regarding our products.the fact is that moat of our competitors also keep such information private and confidential.i sincerely hope that this does not inconvenience you in any way.if there is any other way in which we can help you,do not hesitate to contact us again.truly yours,写英文邮件范文(篇三)dear sir or madam,it is a pleasure to know of your continued interest in our products.the samples you have requested are now available and will be sent free of charge.we have sent the package via fedeX,with airway bill number 8180-XXXX-XXXX.we hope you find these samples your would like to reiterate that we accept customization of products to suit your requirements.plesse do not hesitate to contact us for any further look forward to doing business with you.with best withes,hillary写英文邮件范文(篇四)Dear ___,Congratulations on your good news of ....My fellow managers and I are delighted that your work in the marketing field has been recognized this way and we join in sending you our very best wishes for the future.Through the five years of working together with you, many of us well aware of how much youve contributed to the association beeen our o corporations.We are all looking forward toyour trip to China ne_t month when we will celebrate your advancement in a more formal way.Again, congratulations to you, Mr.Haskel - good luck and good wishes on your new position as Director of Marketing Department.Cordially yours(Signature)Lin DamingMarketing DirectorBeijing New Metals写英文邮件范文(篇五)dear sir or madam,it is a pleasure to know of your continued interest in ourproducts.the samples you have requested are now available and will be sent free of charge.we have sent the package via fedeX,with airway bill number 8180-8713-0983.we hope you find these samples your would like to reiterate that we accept customization of products to suit your requirements.plesse do not hesitate to contact us for any further look forward to doing business with you.with best withes,hillary写英文邮件范文(篇六)dear sir or madam,it is a pleasure to know of your continued interest in our samples you have requested are now are free of charge,but according to our company’ policy,the costomer must pay the shipping cost.samples will be sent immediately as soon as the standard us$70 shipping payment is transferred to our account no.9-2432 at hong kong &shanghai banking corporation(hsbc)or when you provide us with your dhl , ups or fedeX account number.sorry for the onconvenience, i hope this little formslity will not stand in the way of our future relationship.we hope you can understand our position and look forward to our future cooperation.with best ragards,XX写英文邮件范文(篇七)Dear Tom,Im just writing to let you know that were all well, and I hope you are, too.Unfortunately, Ive got some rather bad news for you: Im afraid I made a bit of a mess of Johns car.Anyway,heres what happened.We were on our way to Carols after a long party, and I suppose it must have been about eleven o’clock.Well, the last few miles back home were really dark and deserted.I now realize I was probably going a bit too fast for a country lane because,although the road was fairly straight, I drove up onto the curb and went into a tree.Of course,John was absolutely furious and started shouting at me and cursing.After we d argued for a few moments,we decided to look at the damage, and he calmed down a bit.Well,we found we could move the car, but the wing was caught on the wheel, so we couldnt drive it.I tried to pull the wing clear,but I didnt succeed.Anyway, John went off to phone for a breakdown lorry, but while he was away, I had another go at the wing and this time succeeded in pulling it right off.I threw it onto the back seat,and by that time John got back and we were ready to go?so we didnt need the breakdown lorry at all.John has more or less forgiven me now, but he was very angry with me for a few days.I suppose I was a bit careless.Well, thats all for now.Ne_t time I write I hope Ill have better news for you.Yours sincerely,Linda Chen写英文邮件范文(篇八)Dear Tom,You asked me my idea about traveling。

英语邮件的格式及范文

英语邮件的格式及范文

英语邮件的格式及范文相信大家在写英文邮件的时候会在文本格式方面有所苦恼,而好的邮件格式可以说是会面前或一种给人第一印象的最初评判标准,所以了解好邮件的正确或规范的格式是非常有必要的。

以下是店铺为大家带来英语邮件写作格式及范文,以供大家参阅!英文邮件写作格式一、主题主题(Subject)框的内容应简明地概括信的内容,短的可以是一个单词,如greetings;长的可以是一个名词性短语,也可以是完整句,但长度一般不超过35个字母。

YES:Supplier trainingNO:professional trainees from sister company should abide by rule of local company(太长)主题框的内容切忌含糊不清。

NO:像News about the meeting 这样的表达,YES:应改为T omorrow's meeting canceled。

一般来说,只要将位于句首的单词和专有名词的首字母大写即可。

另外一种较为正规的格式可将除了少于5个字母的介词、连接词或冠词之外的每一个单词的首字母大写。

YES:New E-mail Address Notification;Detailed calculationNO:detailed calculation视信的内容是否重要,还可以开头加上URGENT或者FYI(For Your Information,供参考),如:URGENT:Submit your report today!二、称呼1、E-mail一般使用非正式的文体,因此正文(Body)前的称呼(Salutation)通常无须使用诸如Dear Mr. John之类的表达。

在同辈的亲朋好友或同事间可以直呼其名,但对长辈或上级最好使用头衔加上姓。

YES:Tommy,或者Mr. Smith。

2、称呼和正文之间,段落之间,正文和信尾客套话之间一般空一行,开头无须空格。

Email英语电子邮件写作

Email英语电子邮件写作

A 英文邮件如何写a.内容1.从问候开始用问候语开始邮件内容非常重要,例如"Dear Lillian,"。

根据你与收件人的关系亲近与否,你可能选择使用他们的姓氏来称呼他们而不是直呼其名,例如"Dear Mrs. Price,"。

如果关系比较亲密的话,你就可以说,"Hi Kelly,"如果你和公司联系,而不是个人,你就可以写"To Whom It May Concern:"感谢收件人如果你在回复客户的询问,你应该以感谢开头。

例如,如果有客户想了解你的公司,你就可以说,"Thank you for contacting ABC Company."如果此人已经回复过你的一封邮件了,那就一定要说,"Thank you for your prompt reply."或是"Thanks for getting back to me."如果你可以找到任何机会那一定要谢谢收信人。

这样对方就会感到比较舒服,而且显得更礼貌。

2.表明你的意图然后,如果是你主动写电子邮件给别人的话,那就不可能再写什么感谢的字句了。

那就以你写此邮件的目的开头。

例如,"I am writing to enquire about…"或是"I am writing in reference to …"在电子邮件开头澄清你的来意非常重要,这样才能更好的引出邮件的主要内容。

记得要注意语法,拼写和标点符号,保持句子简短明了并句意前后一致。

3.结束语在你结束邮件之前,再次感谢收信人并加上些礼貌语结尾。

你可以"Thank you for your patience and cooperation."或"Thank you for your consideration."开始接着写, "If you have any questions or concerns, don't hesitate to let me know."及"I look forward to hearing from you."结束最后是写上合适的结尾并附上你的名字。

写英文邮件范文

写英文邮件范文

写英文邮件范文在现代社会中,英文邮件已经成为了商务沟通的重要方式。

无论是与国外客户合作,还是与国外同事交流,都需要用到英文邮件。

因此,如何写一封得体的英文邮件成为了许多人需要掌握的技能。

下面就来分享一些英文邮件的范文和技巧。

首先,写英文邮件时要注意礼貌用语。

比如在开头可以用“Dear”来称呼收件人,结尾可以用“Sincerely”或“Best regards”等来表示诚挚的问候。

在邮件的正文部分,也要使用礼貌用语,比如“please”、“thank you”等。

下面是一个范文:Dear Mr./Ms. [收件人姓名],I hope this email finds you well. I am writing to inquire about [询问的事情].Could you please provide me with more information on [详细内容]? I would greatly appreciate your assistance in this matter.Thank you for your attention to this matter. I look forward to your prompt response.Sincerely,[你的姓名]其次,写英文邮件时要注意语法和用词。

要尽量避免使用生僻词汇和复杂句式,尽量用简洁清晰的语言表达自己的意思。

同时,要注意检查邮件中的拼写和语法错误,以确保邮件的准确性和流畅性。

下面是一个范文:Dear [收件人姓名],I am writing to follow up on our previous discussion regarding the [具体事项]. I would like to confirm the details and ensure that we are on the same page.Could you please provide me with the updated information at your earliest convenience?I appreciate your attention to this matter and look forward to your prompt response.Best regards,[你的姓名]最后,写英文邮件时要注意邮件的格式和结构。

英文Email应该怎么写

英文Email应该怎么写

英文Email应该怎么写需要写的英文邮件多了,就觉得很吃力,尤其是当需要经常写给同一个人时。

希望邮件的开头、结尾、一些客套的话能有不同的表达。

接下来,小编给大家准备了英文Email应该怎么写,欢迎大家参考与借鉴。

英文Email应该怎么写邮件的开头:感谢读者是邮件开场白的好办法。

感谢您的读者能让对方感到高兴,特别是之后你有事相求的情况下会很有帮助。

Thank you for contacting us.如果有人写信来询问公司的服务,就可以使用这句句子开头。

向他们对公司的兴趣表示感谢。

Thank you for your prompt reply.当一个客户或是同事很快就回复了你的邮件,一定记得要感谢他们。

如果回复并不及时,只要将“prompt”除去即可,你还可以说,“Thank you for getting back to me.”Thank you for providing the requested information.如果你询问某人一些信息,他们花了点时间才发送给你,那就用这句句子表示你仍然对他们的付出表示感激。

Thank you for all your assistance.如果有人给了你特别的帮助,那一定要感谢他们!如果你想对他们表示特别的感激,就用这个句子,“I truly appreciate … your help in resolving the problem.”Thank you raising your concerns.就算某个客户或是经理写邮件给你对你的工作提出了一定的质疑,你还是要感谢他们。

这样你能表现出你对他们的认真态度表示尊重及感激。

同时,你也可以使用,“Thank you for your feedback.”在邮件的结尾:在邮件开头表示感谢一般是表示对对方过去付出的感谢,而在邮件结尾处表示感谢是对将来的帮助表示感谢。

事先表示感谢,能让对方在行动时更主动更乐意。

英语电子邮件的范文7篇

英语电子邮件的范文7篇

英语电子邮件的范文7篇English E-mail model英语电子邮件的范文7篇小泰温馨提示:写作是运用语言文字符号以记述的方式反映事物、表达思想感情、传递知识信息、实现交流沟通的创造性脑力劳动过程。

本文档根据写作活动要求展开说明,具有实践指导意义,便于学习和使用,本文下载后内容可随意修改调整修改及打印。

本文简要目录如下:【下载该文档后使用Word打开,按住键盘Ctrl键且鼠标单击目录内容即可跳转到对应篇章】1、篇章1:英语电子邮件的范文2、篇章2:英语电子邮件的范文3、篇章3:英语电子邮件的范文4、篇章4:英语作文电子邮件范文5、篇章5:英语作文电子邮件范文6、篇章6:英语作文电子邮件范文7、篇章7:电子邮件email的邮件格式文档国际商务英语的出现既是社会发展的必然结果,也是英语语言学自身发展的必然趋势。

在21 世纪初知识经济初见端倪的时代,国际商务英语作为英语的重要功能变体之一,正日益显示出其强大的生命力:其应用性和普及性是显而易见的。

下面是小泰为你带来的英语电子邮件的范文,欢迎参阅。

篇章1:英语电子邮件的范文24th November 20##Foshan Sweethome Installations Ltd.2 Xiyue StreetFoshan, GuangdongDear sirs,In reply to your letter of 21st Novermber, We have pleasure in enclosing a detailed quotation for bathroom showers.Besides those advertised in the Builers Joural, our illustrated catalogue also encolsed shows various types of bathroom fittings and the sizes available. Most types can be supplied from stock. 45-60 days should be allowed for delivery of those marked with an asterisk.Building contractors in Hong Kong and Taiwan have found our equipment easy to install and attractive in apperance. Naturally all parts are replacable. and ourquotation includes prices of spare parts. We can allow a 2% discount on all orders of US$6,000 in value and overf, and a 3%on orders exceeding US$20,000.Any orders you place with us will be processed promptly.yours faithfully.Francesco MaraniSales ManagerVia S.Lorenzo, 24/aCastellon SpainTel:(964) 560001 Fax (964) 560002篇章2:英语电子邮件的范文【按住Ctrl键点此返回目录】Koppermann GmbHSchubert strasse 16, K-2618, Hamburg, GermanyTelefon: 1 41 61 00 00 Telefax: 0 41 61 00 012 April 200#Ms Ni Minzhi3W Co. Ltd.3B Guihua RoadShanghai 20xx33Dear Ms Ni,Order No. 9953Thank you for your order which has been completed and is being sent to your today.As agreed we have forwarded our bill, No, 2782 for DM1720.00 with the documents to your bank ,Industrial & Commercial Bank of China, Caohejing Branch, Shanghai. The Draft has been made out for payment 30 days after sight, and the documents will be handed to you on acceptance.Yours sincerelyH. KoppermannManaging Director篇章3:英语电子邮件的范文【按住Ctrl键点此返回目录】Kiddie Korner,Inc. March 2nd,20xx Datex Trading Co. Ltd. Lianfang building 666 Huayuan Avenue Dalian,Liaoning ChinaDear Sir or Madam,We were impressed by the selection of sweaters that were displayed on your stand at the Menswear Exhibition that was held in Chicago last month.We are a large chain of retailers and looking for a manufacturer who could supplyus with a wide range of sweaters for the teenage market.As we usually place very large orders,we would expect a quantity discount in addition to a 20% trade discount off net list prices,and our terms of payment are normally 30 days bill of exchange,documents against payment.If these conditions interest you,and you can meet orders of over 1000 garments at one time,pleasesend us your current catalogue and price-list.We hope to hear from you soon.Yours faithfully,Fred JohnsChina Trade Manager篇章4:英语作文电子邮件范文【按住Ctrl键点此返回目录】Dear David,I’m glad you’ll come to Beijing to learn Chinese. Chinese is very useful, and many foreigners are learning it now. It’s difficult for you because it’s quite different from English. You have to remember as many Chinese words as possible. It’s also important to do some reading and writing. You can watch TV and listen to the radio to practice your listening. Do your best to talk with people in Chinese. You can learn Chinese not only from books but alsofrom people around you. If you have any questions, please ask me. I’m sure you’ll learn Chinese well.Hope to see you soon in Beijing篇章5:英语作文电子邮件范文【按住Ctrl键点此返回目录】Dear Allen,I've got your E-mail. Thank you for your rapid reply! You know what that was my first time to write an E-mail, and it was so fun! I even wrote the wrong address at the first time .How silly I am! About the E-mail you sent me, the flash game is so interesting,and I forward it to my classmate. Everybody says it's the best game they ever played. It's so nice of you to send me the game. Where did you find the game? By the way, would you like to see a movie with me this Saturday? I hear that there is a cool movie and I have two tickets. Please give me the answer before Friday, so that I can make the plan.PS: Can you tell me how to beat the game or give me the work through? Thanks.Best regards,篇章6:英语作文电子邮件范文【按住Ctrl键点此返回目录】15 huaihai streetshanghai, chinafeb 6th, XXpeter brown22、blachpool road(可以省略)sydney 2140dearpeter,i am very glad to hear fromyou._______________________________________________________________________ ____________________________________________________ ___i must stop writing now, as i have a lot of work to do.best wishes to you!sincerely yours, wang xiaolan篇章7:电子邮件email的邮件格式文档【按住Ctrl键点此返回目录】英文书信是一种最常用的应用文体,对于普通的私人信件通常由五部分组成:1.信头:指发信人的地址和日期。

如何优雅地写英文邮件

如何优雅地写英文邮件

如何优雅地写英文邮件本文分为四个部分来展开:基本的邮件格式、常见的邮件委婉/礼貌用语、礼貌用语简短总结、邮件示例基本的邮件格式1.Begin with a greeting一般来说,英文邮件的开头会用Dear xxx;如果你们的关系更加随意、更加熟悉,可以用Hello / Hi xxx;如果你和收件人的关系比较正式,比如是上下级关系,可以用Dear Prof. xxx / Mr. xxx (surname);如果你不知道对方的名字,可以用To whom it may concern or Dear Sir / Madam。

2. Thank the recipientI hope this email finds you well. (use when you are starting the email munication)Thank you for contacting ABC Company. (回复客户咨询)Thank you for your prompt reply. / Thanks for getting back to me. (收到收件人的回复后再发邮件)Thanks much for letting me know! (用于回复邮件,对他人在上封邮件中提供的信息表示感激)Hope you have had a wonderful winter break!That will be great! (用于肯定上封邮件)I will take care of it. // 我会处理好的3. State your purpose / introductory sentenceI am writing to enquire about … 我写电子邮件是想问一下 ...I am writing in reference to ... 我写信是关于I am writing with regard to ...I am writing in connection with ...if you're writing an email to send information, you can start with one of the following sentences:I am writing to let you know ...I am delighted to tell you … (if you're municating good news)I regret to inform you that … (if you're municating bad news)4. Add your closing remarks 添加你的结束语You might start with Thank you for your patience and cooperation or Thank you for your consideration and then follow up with, if you have any questions or concerns, don't hesitate to let me know and I look forward to hearing from you.其他的再比如:Thank you in advancePlease accept our apologies.Please find attached a copy of my resume. I look forward to hearing from you.5. End with a closingThe last step is to include an appropriate closing with your name. Best regards, Sincerely , and Thank you are all professional. Avoid closings such as “Best wishes” or “Cheers” unless you are good friends with the reader.常见的邮件委婉/礼貌用语(to be indirect and polite)1.Simple requests (the reader has an obligation toply with your request)Asking an employee or coworker to do something thathe/she normally handles礼貌程度:Would you mind ... > Could you ... please> Can you ... pleasee.g. Would you mind taking a look at this?2. Favors and Big Requests (the reader does not have an obligation to ply with your request)Getting help with something that you normally handle yourself / Special requestsI was hoping you could…I was wondering if you could…Do you think you might be able to…?Favors and big requests require "softer" language. One way to make language softer is by using past tenses.Another way we make language softer is by using modals 情态动词 (might, could).3. Permission 这种情况与上面 Favors and Big Requests 类似Vacation requests / Time off requests / Borrowing somethingI was hoping I could…I was wondering if I could…Would it be okay if I…?Do you think I might be able to…?4. SuggestionsOffering your point of view / Suggesting a better way of doing somethingWhat about if…?Maybe we could…?I thought it might be a good idea to…5. Rejecting/Refusing/DecliningRejecting offers, suggestions, proposals/ideasI’m not sure that…I don't know if…6. Pointing out a MistakeBilling mistakesIt looks like…It seems…7. Checking on the Status of Something-Finding out if something is finished-Gently reminding someone that you need somethinghe/she is working onHave you had a chance to finish/work on…?礼貌用语简短总结1.Modalsmight, can, could, would2. Distancing phrases (not using the present tense)I was hoping…, I was wondering…, I wanted to…3. Tentative languageMaybe…, Perhaps…, I’m not sure if…, I don’t know if…, might4. Introductory phrasesIt looks like…, It seems like…, Actually…,To be honest…Well…, I see what you’re saying (but…),5. Positive language (avoiding negative expressions like “bad,” “won’t work,”“ineffective,” etc.)It might not be the best approach.邮件示例e.g. 1Thanks much for letting me know!It is a great opportunity for me to learn more about most related xxx knowledge. I will attend the meeting for sure.Ref:。

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这样写英文Email,对方会感觉你很有礼貌,很有风度一、投稿信1. Dear Dr. Defendi ML:I am sending a manuscript entitled “” by – which I should like to submit for possible publication in the journal of - .Yours sincerely2. Dear Dr. A:Enclosed is a manuscript entitled “” by sb, whi ch we are submitting for publication in the journal of - . We have chosen this journal because it deals with - . We believe that sth would be of interest to the journal’s readers.3. Dear Dr. A:Please find enclosed for your review an original research art icle, “” by sb. All authors have read and approve this version of the article, and due care has been taken to ensure the integrity of the work. No part of this paper has published or submitted elsewhere. No conflict of interest exits in the submission of this manuscript, and we have attached to this letter the signed letter granting us permission to use Figure 1 from another source.We appreciate your consideration of our manuscript, and we look forward to receiving comments from the reviewers.二、询问有无收到稿件Dear Editors,We dispatched our manuscript to your journal on 3 August 2006 but have not, as yet, receive acknowledgement of their safe arrival. We fear that may have been lost and should be grateful if you would let us know whether or not you have received them. If not, we will send our manuscript again. Thank you in advance for your help.三、询问论文审查回音Dear Editors,It is more than 12 weeks since I submitted our manuscript (No: ) for possible publication in your journal. I have not yet received a reply and am wondering whether you have reached a decision. I should appreciated your letting me know what you have decided as soon as possible.四、关于论文的总体审查意见1. This is a carefully done study and the findings are of considerable interest. A few minor revision are list below.2. This is a well-written paper containing interesting results which merit publication. For the benefit of the reader, however, a number of points need clarifying and certain statements require further justification. There are given below.3. Although these observation are interesting, they are rather limited and do not advance our knowledge of the subject sufficiently to warrant publication in PNAS. We suggest that the authors try submitting their findings to specialist journal such as –4. Although this paper is good, it would be ever better if some extra data were added.5. This manuscript is not suitable for publication in the journal of – because the main observation it describe was reported 3 years ago in a reputable journal of - .6. Please ask someone familiar with English language to help you rewrite this paper. As you will see, I have made some correction at the beginning of the paper where some syntax is not satisfactory.7. We feel that this potentially interesting study has been marred by an inability to communicate the finding correctly in English and should like to suggest that the authors seek the advice of someone with a good knowledge of English, preferable native speaker.8. The wording and style of some section, particularly those concerning HPLC, need careful editing. Attention should be paid to the wording of those parts of the Discussion of and Summary which have been underlined.9. Preliminary experiments only have been done and with exception of that summarized in Table 2, none has been repeated. This is clearly unsatisfactory, particularly when there is so much variation between assays.10. The condition of incubation are poorly defined. What is the temperature? Were antibody used?五、给编辑的回信1. In reply to the referee’s main criticism of paper, it is possible to say that –One minor point raised by the referee concerns of the extra composition of the reaction mixture in Figure 1. This has now been corrected. Further minor changes had been made on page 3, paragraph 1 (line 3-8) and 2 (line 6-11). These do not affect our interpretation of the result.2. I have read the referee’s comments very carefully and conclude that the paper has been rejected on the sole grounds that it lake toxicity data. I admit that I did not include a toxicity table in my article although perhaps I should have done. This was for the sake of brevity rather than an error or omission.3. Thank you for your letter of –and for the referee’s comments concerning our manuscript entitled “”. We have studied their comments carefully and have made correction which we hope meet with their approval.4. I enclosed a revised manuscript which includes a report of additional experiments done at the referee’s suggestion. You will see that our original findings are confirmed.5. We are sending the revised manuscript according to the comments of the reviewers. Revised portion are underlined in red.6. We found the referee’s comments most helpful and have revised the manuscript7. We are pleased to note the favorable comments of reviewers in their opening sentence.8. Thank you for your letter. I am very pleased to learn that our manuscript is acceptable for publication in Cancer Research with minor revision.9. We have therefore completed a further series of experiments, the result of which are summarized in Table 5. From this we conclude that intrinsic factor is not account.10. We deleted the relevant passage since they are not essential to the contents of the paper.11. I feel that the reviewer’s comments concerning Figures 1 and 2 result from a misinterpretation of the data.12. We would have include a non-protein inhibitor in our system, as a control, if one had been available.13. We prefer to retain the use of Table 4 for reasons that it should be clear from the new paragraph inserted at the end of the Results section.14. Although reviewer does not consider it is important to measure the temperature of the cells, we consider it essential.15. The running title has been changed to “”.16. The Materials and Methods section now includes details for measuring uptake of isotope and assaying hexokinase.17. The concentration of HAT media (page12 paragraph 2) was incorrectly stated in the original manuscript. This has been rectified. The authors are grateful to the referees for pointing out their error.18. As suggested by both referees, a discussion of the possibility of laser action on chromosome has been included (page16, paragraph 2).19. We included a new set of photographs with better definition than those originally submitted and to which a scale has been added.20. Following the suggestion of the referees, we have redraw Figure 3 and 4.21. Two further papers, published since our original submission, have been added to the text and Reference section. These are:22. We should like to thank the referees for their helpful comments and hope that we have now produced a more balance and better account of our work. We trust that the revised manuscript is acceptable for publication.23. I greatly appreciate both your help and that of the referees concerning improvement to this paper. I hope that the revised manuscript is now suitable for publication.24. I should like to express my appreciation to you and the referees for suggesting how to improve our paper.25. I apologize for the delay in revising the manuscript. This was due to our doing an additional experiment, as suggested by referees.邮件的开头感谢读者是邮件开场白的好办法。

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