安捷伦6410液质联用资料 New Era in LC-MS Quantitative Analysis(Agilent MassHunter Workstation )
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Resp. Factor 1546 RSD 2.0%
1 pg
Resp. Factor 1542 RSD 0.9% 10 pg
MRM Parameters: 3 transitions 100msec dwell/transition 315msec cycle time 239.8-238.9 (precursor ion) 239.8-132.0 (quantifier ion) 239.8-196.8 (qualifier ion)
+
=
New Era in LC/MS Quantitative Analysis
Page 2
New Era in LC/MS QuantAnalysis May 31, 2006
Program
Agilent 6410 QQQ Hardware – 10 min.
• Performance, Reliability, Ease-of-Use, Cost of Ownership
Agilent MassHunter Workstation Software – 30 min.
• Fast Learning Curve, Ease-of-Use, Productivity, Reporting • Acquisition Software • Quantitative Analysis Software Features - Life Demos
+
=
New Era in LC/MS Quantitative Analysis
Page 3
New Era in LC/MS QuantAnalysis May 31, 2006
Design Objectives for the 6410 Triple Quad LC/MS
What are the biggest issues which customers face in QQQ LC/MS/MS Quantitation HARDWARE
Page 4
Leabharlann Baidu
New Era in LC/MS QuantAnalysis May 31, 2006
Performance – Bentazon Herbicide 100 fg LOQ
Femtogram sensitivity with excellent reproducibility
Resp. Factor 1512 RSD 14.0% 100 fg
?
• High analytical performance
• Reliability • Ease of use • Low cost of ownership
For food safety, environmental, chemical, forensics, pharmaceutical and metabolomics markets
Future
• 21CFRPart 11 Compliance • Automated MRM Acquisition Method Development • Support of all Agilent MS instrumentation (LC/MS, GC/MS, ICP/MS)
Questions
• Batch-At-A Glance User Interface and Navigation • Quant Method Editor • Outlier Flagging and Filtering on over 20 Parameters • Parameter-less MSMS Integrator w/ built-in peak validation • Curve Fit Assistant and other Productivity Tools • Powerful reporting based on Excel 2003 Pro and XML - Life Demo
• Batch-At-A Glance User Interface and Navigation • Quant Method Editor • Outlier Flagging and Filtering on over 20 Parameters • Parameter-less MSMS Integrator w/ built-in peak validation • Curve Fit Assistant and other Productivity Tools • Powerful reporting based on Excel 2003 Pro and XML - Life Demo
Future
• 21CFRPart 11 Compliance • Automated MRM Acquisition Method Development • Support of all Agilent MS instrumentation (LC/MS, GC/MS, ICP/MS)
Questions
Resp. Factor 1526 RSD 0.8% 100 pg
Resp. Factor 1009 RSD 1.1% 1 ng
Agilent MassHunter Workstation Software – 30 min.
• Fast Learning Curve, Ease-of-Use, Productivity, Reporting • Acquisition Software • Quantitative Analysis Software Features - Life Demos
安捷伦6410液质联用资料 New Era in LC-MS Quantitative
Analysis(Agilent MassHunter Workstation )
Program
Agilent 6410 QQQ Hardware – 10 min.
• Performance, Reliability, Ease-of-Use, Cost of Ownership
1 pg
Resp. Factor 1542 RSD 0.9% 10 pg
MRM Parameters: 3 transitions 100msec dwell/transition 315msec cycle time 239.8-238.9 (precursor ion) 239.8-132.0 (quantifier ion) 239.8-196.8 (qualifier ion)
+
=
New Era in LC/MS Quantitative Analysis
Page 2
New Era in LC/MS QuantAnalysis May 31, 2006
Program
Agilent 6410 QQQ Hardware – 10 min.
• Performance, Reliability, Ease-of-Use, Cost of Ownership
Agilent MassHunter Workstation Software – 30 min.
• Fast Learning Curve, Ease-of-Use, Productivity, Reporting • Acquisition Software • Quantitative Analysis Software Features - Life Demos
+
=
New Era in LC/MS Quantitative Analysis
Page 3
New Era in LC/MS QuantAnalysis May 31, 2006
Design Objectives for the 6410 Triple Quad LC/MS
What are the biggest issues which customers face in QQQ LC/MS/MS Quantitation HARDWARE
Page 4
Leabharlann Baidu
New Era in LC/MS QuantAnalysis May 31, 2006
Performance – Bentazon Herbicide 100 fg LOQ
Femtogram sensitivity with excellent reproducibility
Resp. Factor 1512 RSD 14.0% 100 fg
?
• High analytical performance
• Reliability • Ease of use • Low cost of ownership
For food safety, environmental, chemical, forensics, pharmaceutical and metabolomics markets
Future
• 21CFRPart 11 Compliance • Automated MRM Acquisition Method Development • Support of all Agilent MS instrumentation (LC/MS, GC/MS, ICP/MS)
Questions
• Batch-At-A Glance User Interface and Navigation • Quant Method Editor • Outlier Flagging and Filtering on over 20 Parameters • Parameter-less MSMS Integrator w/ built-in peak validation • Curve Fit Assistant and other Productivity Tools • Powerful reporting based on Excel 2003 Pro and XML - Life Demo
• Batch-At-A Glance User Interface and Navigation • Quant Method Editor • Outlier Flagging and Filtering on over 20 Parameters • Parameter-less MSMS Integrator w/ built-in peak validation • Curve Fit Assistant and other Productivity Tools • Powerful reporting based on Excel 2003 Pro and XML - Life Demo
Future
• 21CFRPart 11 Compliance • Automated MRM Acquisition Method Development • Support of all Agilent MS instrumentation (LC/MS, GC/MS, ICP/MS)
Questions
Resp. Factor 1526 RSD 0.8% 100 pg
Resp. Factor 1009 RSD 1.1% 1 ng
Agilent MassHunter Workstation Software – 30 min.
• Fast Learning Curve, Ease-of-Use, Productivity, Reporting • Acquisition Software • Quantitative Analysis Software Features - Life Demos
安捷伦6410液质联用资料 New Era in LC-MS Quantitative
Analysis(Agilent MassHunter Workstation )
Program
Agilent 6410 QQQ Hardware – 10 min.
• Performance, Reliability, Ease-of-Use, Cost of Ownership