Hoechst_33258_DataSheet_MedChemExpress
说明书
Hoechst 33258CAS#：23491-45-4化学名：2’-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5’-bi-1H-benzimidazole, trihydrochloride别名：Hoechst 33258，bisBenzimide H 33258，HOE 33258结构式：分子式：C25H24N6O · 3HCl分子量：533.88性质：1. 外观：黄色粉末2. 纯度：≥95%（HPLC）3. 产品描述：Hoechst 33258是一种可以穿透细胞膜的蓝色荧光染料，对细胞的毒性较低。
Hoechst 33258染色常用于细胞凋亡检测，染色后用荧光显微镜观察或流式细胞仪检测。
也常用于普通的细胞核染色，或常规的DNA染色。
Hoechst 33258的最大激发波长为346nm，最大发射波长为460nm。
Hoechst 33258和双链DNA结合后，最大激发波长为352nm，最大发射波长为461nm。
Hoechst 33258溶于水，溶解度可达10mg/mL。
4. 染色程序：（1）用PBS或合适的缓冲液制备10～50µM Hoechst33258染料。
（2）将1/10细胞培养基体积的Hoechst染料溶液加入细胞培养物中（可以用1/10浓度的Hoechst染料缓冲液代替培养基）。
（3）在37℃培养细胞10～20分钟。
（4）用PBS或合适的缓冲液洗细胞两次。
（5）用带有352nm激发波长，461nm发射波长的滤光片的荧光显微镜观察细胞。
储存条件：-20℃，避光保存注意事项：Hoechst 33258对人体有一定刺激性，请注意适当防护。
荧光染料都存在淬灭的问题，建议染色后尽量当天完成检测。
为减缓荧光淬灭可以使用抗荧光淬灭封片液。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
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hoechst33258染色原理
hoechst33258染色原理Hoechst 33258染色原理及其应用一、引言Hoechst 33258是一种广泛应用于细胞生物学和分子生物学研究中的DNA染色剂。
它能够与DNA结合形成荧光复合物，通过荧光显微镜观察，可以对细胞核进行定位和分析。
本文将介绍Hoechst 33258染色原理及其应用。
二、Hoechst 33258染色原理Hoechst 33258是一种荧光染料，其化学结构中含有两个吡啶环和一个三嗪环。
该染料可以通过静电作用与DNA结合，形成稳定的染色复合物。
Hoechst 33258与DNA的结合是通过静电相互作用和氢键形成的。
静电相互作用是指Hoechst 33258的阳离子部分与DNA 的阴离子部分之间的吸引力。
氢键是指Hoechst 33258与DNA之间氢键的形成，通过吡啶环与DNA中的腺嘌呤碱基之间的氢键相互作用。
三、Hoechst 33258染色的步骤Hoechst 33258染色一般包括以下几个步骤：1. 细胞固定：将待染色的细胞进行固定，常用的方法有甲醛固定、乙醛固定等。
2. 细胞透化：使用适当的透化剂，如Triton X-100等，使细胞膜通透。
3. Hoechst 33258染色：将Hoechst 33258溶液加入到细胞中，使其与DNA结合。
4. 荧光显微镜观察：使用荧光显微镜观察染色结果，Hoechst 33258与DNA结合后产生蓝色荧光。
四、Hoechst 33258染色的应用1. 染色体分析：Hoechst 33258可以用于染色体的分析，通过观察染色体形态和数量的变化，可以研究染色体的结构和功能。
2. 细胞核定位：Hoechst 33258与DNA结合后产生荧光信号，可以用于细胞核的定位。
通过观察荧光信号的位置和强度变化，可以判断细胞核的形态和位置。
3. 细胞凋亡检测：细胞凋亡是一种重要的细胞死亡方式，Hoechst 33258可以用于检测细胞凋亡。
Hoechst33258 荧光染色法
Hoechst33258 荧光染色法【试剂盒不同，固定染色时间不同。
】
①人肝癌细胞HepG2经常规传代培养至对数期，弃去旧培养液，用0.25%胰蛋白酶溶液消化后制成单细胞悬液，调整细胞密度为1× 106 /ml，接种于6孔培养板中。
置于37°C、5%CO2 恒温细胞培养箱中培养24h后，观察细胞贴壁情况。
②待贴壁细胞密度达到80%后，弃去培养液，用PBS小心冲洗细胞两遍，加入不同浓度的人参皂苷转化物溶液200μl，继续培养24h。
③24h后消化收集细胞，1000r/min离心5min，弃去上清液；用PBS重悬细胞，1000r/min离心洗涤2 次；
④第二次离心洗涤后留少许上清，用微量加样器吸取细胞在洁净载玻片上涂片，室温自然干燥；随即使用甲醇∶冰醋酸(3∶1)固定液固定15 min；
⑤晾干后于暗处用Hoechst 33258 染色工作液(10mg/l)避光染色10 min后用双蒸
水冲洗5min，抗淬灭封片液封片；
⑥置于激光共聚焦显微镜下，激发波长350nm，发射波长460nm，观察细胞凋亡情况并拍照。
①人肝癌细胞HepG2经常规传代培养至对数期，弃去旧培养液，用0.25%胰蛋白酶溶液消化后制成单细胞悬液，调整细胞密度为5×105/ml，接种于6孔培养板中。
置于37℃、5%CO2 恒温细胞培养箱中培养24h后，观察细胞贴壁情况。
②待贴壁细胞密度达到80%后，弃去培养液，用PBS小心冲洗细胞两遍，一孔加入含10%胎牛血清的完全培养液，其余各孔分别加入高、中、低3个浓度的人参皂苷转化物溶液与顺铂溶液200μl，继续培养48h。
③倒置显微镜下观察各组细胞生长情况和形态变化。
Hoechst染色
Hoechst 染料Hoechst是一类DNA染料。
读音hoaxt(类似于‘赫克斯特’)最初由Hoechst AG公司发明。
这是一家德国公司，创建于1863年，后来经过数次合并，变成了Sanofi-Aventis（赛诺菲）集团的子公司。
它们所有的试剂都以数字编号命名，也就是说Hoechst 33342是该公司合成的的第33342种化合物。
类似的染料一共有三种：Hoechst 33258, Hoechst 33342, 和Hoechst 34580。
33342和33258最常用，激发/发射光谱也比较接近。
分子特性三种染料都可在350nm左右的紫外光激发。
都在461nm处发出蓝靛色荧光。
未被结合的染料最大发射光在510到540nm之间。
可被氙-氩灯或水银-氩灯或紫外激光激发。
激发光和发射光之间的斯托克斯位移巨大，故可用于多染料多颜色荧光染色。
Hoechst染料的荧光强度随着溶液pH升高而增强。
Hoechst染料溶于水和有机溶剂，如二甲基甲酰胺或二甲基亚砜。
浓度可高达10mg/mL.水溶液可在4 °C避光保存至少6个月。
长期储存于≤-20 °C Hoechst与DNA双链中的小沟（minor groove）结合，更倾向与于富含A/T（腺嘌呤/胸腺嘧啶）的DNA链。
虽然说它能与所有的核酸结合，但是富含AT的双链DNA使荧光强度显著增强。
Hoechst可穿过细胞膜，可结合于活细胞或固定过的细胞。
因此可用于活细胞标记Hoechst能与DNA结合，干扰DNA复制和细胞分裂，因此有致畸和致癌危险。
使用和废弃需谨慎。
常见细胞核荧光染料
细胞核荧光染料（PI DAPI Hoechst33342）Hoechest 33258 是膜透性的,因此在活细胞时候能轻松进入;DAPI是半透性的,有选择性的进入.因此Hoechest 33258 一般用来染活细胞,可以长驱直入;DAPI一般是染固定细胞.2、两者都可以用紫外看，参见以下的激发发射波长Hoechst 33258的最大激发波长为346nm，最大发射波长为460nm；Hoechst 33258和双链DNA结合后，最大激发波长为352nm，最大发射波长为461nm。
DAPI的最大激发波长为340nm，最大发射波长为488nm；DAPI和双链DNA结合后，最大激发波长为364nm，最大发射波长为454nm。
Hoechst 33342/PI双染色法1．悬浮生长的细胞在培养状态下加入Heochst 33342，终浓度为1μg/ml；帖壁生长的细胞用含有0.02％EDTA的0.25％胰蛋白酶消化成单细胞悬液，离心，弃上清，用1ml全培养液重悬细胞，加入Heochst 33342，终浓度为1μg/ml，37℃孵育7～10min。
2．4℃500～1000r/min离心弃去染液。
3．加入1.0ml PI染液，4℃避光染色15min。
??碘化丙啶染色???? 1．原理? 碘化丙啶(propidium iodide，PI)不能穿人完整的活细胞膜中，即正常细胞和凋亡细胞在不固定的情况下对PI拒染，而坏死细胞由于失去膜的完整性，PI可进入细胞内与DNA结合，根据此特点，使用PI染色可鉴别死细胞。
如果对活细胞染色必须在染色前进行固定，以增加细胞膜对染料的通透性。
???? 2．溶液配制? 使用0．01mol／LPBS(pH 7．4)配制终浓度为0．5mg／ml的PI工作液。
???? 3．染色程序??? (1)单层细胞培养标本经预冷70％乙醇固定1小时，4℃；??? (2)0．01mol／LPBS(pH 7．4)冲洗；??? (3)沥干后加入PI工作液，室温孵育15分钟；??? (4)冲洗后封片。
Hoechst33258染色液
Hoechst 33258染色液简介：Hoechst 33258也称bisBenzimide H 33258或HOE 33258，分子式为C 25H 24N 6O · 3HCl 。
Hoechst 33258是一种可以穿透细胞膜的蓝色荧光染料，对细胞的毒性较低，常用于细胞凋亡检测，染色后用荧光显微镜观察或流式细胞仪检测。
Hoechst 33258也用于普通的细胞核染色、DNA 染色。
Leagene Hoechst 33258染色液可直接用于固定细胞或组织的细胞核染色，也可直接用于活细胞或组织的细胞核染色。
组成：操作步骤(仅供参考)：(一)固定的组织细胞染色1、对于细胞或组织样品，固定后冲洗去除固定剂。
如果需要进行免疫荧光染色，则先进行免疫荧光染色，染色完毕后再按后续步骤进行Hoechst 33258染色，如果不需要进行其它染色，则直接进行后续的Hoechst 33258染色。
2、室温放置，轻轻吸除Hoechst 33258染色液。
4、用无菌的PBS 或生理盐水清洗2～3次。
5、直接在荧光显微镜下观察或封片后荧光显微镜下观察。
(二)活细胞染色1、取96、24、6孔板培养细胞至合适状态，按96孔板加入100μl 、24孔板加入500μl 、6孔板加入1ml 的比例，加入适当的Hoechst 33258染色液，染液必须充分覆盖细胞。
2、在适宜于细胞培养的条件下培养。
3、轻轻吸除Hoechst 33258染色液。
4、用无菌的PBS 或生理盐水清洗2～3次。
5、进行荧光检测。
注意事项：1、 Hoechst 33258染色液的浓度适用于大多数常规染色的需要。
2、 荧光染料都存在淬灭的问题，建议染色后尽快检测。
活细胞或组织染色后宜立即观察。
3、 为减缓荧光淬灭可以使用抗荧光淬灭封片液。
编号 名称 DA0010 Storage Hoechst 33258 Staining Solution 10ml -20℃ 避光 使用说明书1份4、避免反复冻融，否则容易失效。
hoechst33258染色原理
hoechst33258染色原理Hoechst 33258染色原理Hoechst 33258是一种广泛应用于细胞染色的荧光染料，其染色原理基于其特殊的荧光性质。
本文将介绍Hoechst 33258染色的原理以及其在生物学研究中的应用。
Hoechst 33258是一种DNA染料，可以通过与DNA的特异性结合来染色细胞核。
其结构中含有多个芳香环，并且具有两个亲水性基团。
这些特征使得Hoechst 33258能够与DNA的碱基发生作用，并形成稳定的染色复合物。
Hoechst 33258的染色原理可以分为两个步骤：细胞透过性和DNA结合。
Hoechst 33258可以通过细胞膜透过性进入细胞内。
细胞膜是由脂质双层组成的，具有一定的透过性，特别是对于小分子量的化合物。
Hoechst 33258具有较小的分子量和亲水性基团，因此可以通过细胞膜进入细胞。
Hoechst 33258与DNA的碱基发生作用，形成稳定的染色复合物。
DNA是由脱氧核苷酸组成的双链分子，在细胞核中起着储存和传递遗传信息的作用。
Hoechst 33258中的芳香环能够与DNA的碱基发生π-π堆积作用，特别是与腺嘌呤（A）和胸腺嘧啶（T）发生较强的结合。
这种结合使得Hoechst 33258能够选择性地染色细胞核，而不影响其他细胞结构。
Hoechst 33258的染色特点使其成为生物学研究中广泛应用的染料之一。
通过Hoechst 33258染色，可以直观地观察细胞核的形态和数量变化，进而研究细胞增殖、凋亡和分化等生物学过程。
此外，Hoechst 33258还可以用于检测DNA的含量和DNA损伤，以及细胞周期的研究。
在实验中，Hoechst 33258的使用方法相对简单。
首先，将Hoechst 33258溶解在适当的溶液中，再将其加入含有待染细胞的培养基中。
随后，将细胞与Hoechst 33258溶液共孵育一段时间，使其充分染色。
最后，使用荧光显微镜观察细胞，并通过荧光信号的强度和分布来分析细胞核的状态。
Hoechst_33258_analog_SDS_MedChemExpress
Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:May-24-2017Print Date:May-24-20171. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :Hoechst 33258 analogCatalog No. :HY-15623CAS No. :258843-62-81.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureNot a hazardous substance or mixture.2.2 GHS Label elements, including precautionary statementsNot a hazardous substance or mixture.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:NoneFormula:C29H30N6O3Molecular Weight:510.59CAS No. :258843-62-84. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Powder-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance Light yellow to yellow (Solid)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2017 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。
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Inhibitors, Agonists, Screening Libraries
Data Sheet
BIOLOGICAL ACTIVITY:
Hoechst 33258 is a fluorescent dyes, which can be used as a cell dye for DNA.
IC50 & Target: IC50: 51.31±4.56 μM (HeLa cell), 32.43±3.27 μM (HL60 cell), 15.42 ± 2.16 μM (U937 cell)[1]
In Vitro: Hoechst 33258, a fluorescent compound with a head–to–tail bis–benzimidazole structure, is initially found to be cytotoxic against L1210 murine leukemia. Hoechst 33258 is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), Human promyelocytic leukemia cell (HL60) and U937 cell Line. The IC 50 determined in the case of HeLa,HL60 and U937 is 51.31±4.56, 32.43±3.27 and 15.42±2.16 μM for Hoechst 33258, respectively [1]. The cytotoxic property of Hoechst 33258 is investigated on a panel of seven tumour cell lines of different histological origin and Madine–Darby canine kidney (MDCK)normal cells. All cell lines, except MCF–7, exposed to Hoechst 33258 exhibit GI 50 from 84×10–6 to 191.5×10–6 mol dm –3. Under the same experimental conditions, Hoechst 33258, used as a binder reference compound, stops the cell cycle in S phase and G0/G1[2]. PROTOCOL (Extracted from published papers and Only for reference)
Cell Assay:[2]Hoechst 33258 is prepared as stock solutions in highly pure water. Working solutions in a concentration range of 10–3–10–6 mol dm –3 are prepared prior to testing. Cytotoxic effects of Hoechst 33258 on tested cell lines are determined by the MTT assay. Cells are seeded in 96 micro well flat bottom plates at a concentration of 2×104 cells/mL and left overnight in the CO 2incubator allowing them to attach to the plate surface. Growing medium is replaced with compound supplemented or control
medium and incubated for 72 h. Fresh medium with 5 mg/mL of MTT is added onto cells and incubated for 4 h at 37°C. Upon media removal, water insoluble MTT–formazan crystals formed inside the living cells are dissolved in DMSO and the absorbance at 570 nm proportional to the number of living cells is measured on an Elisa Microplate Reader. All experiments are performed at least three times in triplicates.The GI 50 value, defined as the compound concentration (μM) leading to cellular growth inhibition by 50%, is calculated and used as a parameter to compare cytotoxicity among the compounds [2].
References:
[1]. Wang XJ, et al. Newly synthesized bis–benzimidazole derivatives exerting anti–tumor activity through inductionof apoptosis and autophagy. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6297–300.
[2]. Stoli? I, et al. Synthesis, DNA/RNA affinity and antitumour activity of new aromatic diamidines linked by 3,4–ethylenedioxythiophene. Eur J Med Chem.2011 Feb;46(2):743–55.
Product Name:
Hoechst 33258Cat. No.:
HY-15558CAS No.:
23491-44-3Molecular Formula:
C 25H 24N 6O Molecular Weight:
424.50Target:
Others Pathway:
Others Solubility:
DMSO: ≥ 44 mg/mL
Caution: Product has not been fully validated for medical applications. For research use only.
Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@
Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。