最新有关细胞信号通路的参考文献清单

文献题名1Identification of Claudins by Western Blot and Immunofluorescence in Different Cell Lines and Tissues 2Understanding the Role of Stromal PTEN Regulated miR-101 and miR-130b in Tumor Microenvironment 3Regulation of DMD pathology by an ankyrin-encoded miRNA 4A cytokine mixture of GM-CSF and IL-3 that induces a neuroprotective phenotype of microglia leading to amelioration of (6-OHDA)-induced Parkinsonism of rats 5Exome sequencing identifies MVK mutations in disseminated superficial actinic porokeratosis 6Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity 7Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth 8NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain 9Zinc Fingers and Homeoboxes 2 Inhibits Hepatocellular Carcinoma Cell Proliferation and Represses Expression of Cyclins A and E 10p28GANK Prevents Degradation of Oct4 and Promotes Expansion of Tumor-Initiating Cells in Hepatocarcinogenesis 11Prostaglandin E Signaling and Bacterial Infection Recruit Tumor-Promoting Macrophages to Mouse Gastric Tumors 12RN181 suppressed tumor growth of hepatocellular carcinoma by inhibition of the ERK/MAPK pathway 13p28GANK Overexpression Accelerates Hepatocellular Carcinoma Invasiveness and Metastasis via Phosphoinositol 3-Kinase/AKT/Hypoxia-Inducible Factor-1a Pathways 14Brain-derived neurotrophic factor contributes to abdominal pain in irritable bowel syndrome 15Cholesterol sequestration by nystatin enhances the uptake and activity of endostatin in endothelium via regulating distinct endocytic pathways.16Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload 17D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasms 18The oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling 19Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells 20Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice 21NFIL3/E4BP4 controls type 2 T helper cell cytokine expression 22IKK-β mediates hydrogen peroxide induced cell death through p85 S6K123Urine proteome analysis reflects atherosclerotic disease in an ApoE-/- mouse model and allows the discovery of new biomarkers in mouse and human atherosclerosis 24Does insulin bolster antioxidant defenses via the ERK-Akt-Nrf2 pathway ? （0）25Osteogenesis and angiogenesis induced by porous β-CaSiO3/PDLGA compositescaffold via activation of AMPK/ERK1/2 and PI3K/Akt pathways26Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-kB pathways 27An epidermal stem cells niche microenvironment created by engineered human amniotic membrane 28The combined effects of continuous passive motion treatment and acellular PLGA implants on osteochondral regeneration in the rabbit 29PDK1 Regulates Vascular Remodeling and Promotes Epithelial-Mesenchymal Transition in Cardiac Development 30MicroRNA-214 downregulation contributes to tumor angiogenesis via inducing secretion of hepatoma-derived growth factor in human hepatoma 31New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis 32p53-insensitive PUMA down-regulation is essential in the early phase of liver regeneration after partial hepatectomy in mice 33Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis 34A novel XPF −357A>C polymorphism predicts risk and recurrence of bladder cancer （0）35Hippocampal Neuronal Nitric Oxide Synthase Mediates the Stress-Related Depressive Behaviors of Glucocorticoids by Downregulating Glucocorticoid Receptor 36MFG-E8 Mediates Primary Phagocytosis of Viable Neurons during Neuroinflammation 37IRX1 influences peritoneal spreading and metastasis via inhibiting BDKRB2-dependent neovascularization on gastric cancer 38Nanofiber scaffolds facilitate functional regeneration of peripheral nerve injury 39HOXB7 as a prognostic factor and mediator of colorectal cancer progression 40Age-related changes in rostral basal forebrain cholinergic and GABAergic projection neurons: relationship with spatial impairment 41Epigenetic Regulation of DACT2, A Key Component of the Wnt Signaling Pathway in Human Lung Cancer 42Endostatin inhibits tumour lymphangiogenesis and lymphatic metastasis via cell surface nucleolin on lymphangiogenic endothelial cells 43Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer 44Up-regulated miR-17 promotes cell proliferation, tumour growth and cell cycle progression by targeting the RND3 tumour suppressor gene in colorectal carcinoma (0)45Construction of a Portal Implantable Functional Tissue-Engineered Liver UsingPerfusion-Decellularized Matrix and Hepatocytes in Rats46Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction47Toll-like receptor 4 signaling promotes epithelial-mesenchymal transition in human hepatocellular carcinoma induced by lipopolysaccharide48UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation49Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/b-Catenin Signaling50T63, a New 4-Arylidene Curcumin Analogue induces cell cycle arrest and apoptosis through activation of Reactive Oxygen Species-FOXO3a pathway in lung cancer cells 51ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation.52PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf253TRAIL and doxorubicin combination enhances anti-glioblastoma effect based on passive tumor targeting of liposomes 54Expression of PDGFR-β in colorectal cancer stroma and the relationship to lymphangiogenesis 55Aldehyde Dehydrogenase-2 Deficiency Aggravates Cardiac Dysfunction Elicited by Endoplasmic Reticulum Stress Induction 56Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4,and Rab2557Shp2 Plays an Important Role in Acute Cigarette Smoke-Mediated Lung Inflammation 58Nuclear to Cytoplasmic Translocation of Heterogeneous Nuclear Ribonucleoprotein U Enhances TLR-Induced Proinflammatory Cytokine Production by Stabilizing mRNAs in Macrophages 59Identification of Resting and Type I IFN-Activated Human NK Cell miRNomes Reveals MicroRNA-378 and MicroRNA-30e as Negative Regulators of NK Cell Cytotoxicity 60The toxicity evaluation of nano-trititanate with bactericidal properties in vitro 61Quantitative proteomics using stable isotope labeling with amino acids in cell culture (SILAC) reveals protein and pathway regulation in porcine circovirus type 2 infected PK-15 cells 62miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes 63MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol 64MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF 65MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene 66Checkpoint kinase 1 is essential for meiotic cell cycle regulation in mouse oocytes 67The retinoblastoma protein selectively represses E2F1 targets via a TAAC DNA element during cellular senescence 68Roles of the KRAB-associated co-repressor KAP1 S473 phosphorylation in DNA damage response 69Slit2 Regulates the Dispersal of Oligodendrocyte Precursor Cells via Fyn/RhoA Signaling 70Disturbance of Ca2+ Homeostasis Converts Pro-Met into Non-canonical Tyrosine Kinase p190MetNC in Response to Endoplasmic Reticulum Stress in MHCC97 Cells 71Trio Is a Key Guanine Nucleotide Exchange Factor Coordinating Regulation of theMigration andMorphogenesis of Granule Cells in the Developing Cerebellum 72Heme Oxygenase-1/Carbon Monoxide Induces Vascular Endothelial Growth Factor Expression via p38 Kinase-dependent Activation of Sp173The protease allergen Pen c 13 induce allergic airway inflammation and changes in epithelial barrier integrity and function in a murine model 74Protein Kinase C Promotes NMDA Receptor Trafficking by Indirectly Triggering CaMKII Autophosphorylation 75Distinct kinetic and spatial patterns of PKC- and EGFR-dependent activation ofextracellular signal-regulated kinases 1 and 2 by humane nicotinic acid receptor GPR109A76AKT2 suppresses GAPDH mediated-apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocation 77MicroRNA-99a Inhibits Hepatocellular Carcinoma Growth and Correlates with Prognosis of Patients with Hepatocellular Carcinoma 78Aurora B Interaction of Centrosomal Nlp Regulates Cytokinesis （0）79SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2.Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors To Suppress Cell Migration 80Exogenous melatonin modulates apoptosis in the mouse brain induced by high-LET carbon ion irradiation （0）81Cellular Pharmacokinetic Mechanisms of Adriamycin Resistance and Its Modulation by 20(S)-Ginsenoside Rh2 in MCF-7/Adr Cells （0）82Inhibition of autophagy enhances anticancer effects of bevacizumab in hepatocarcinoma 83Functionalized single-walled carbon nanotubes cause reversible acute lung injury and induce fibrosis in mice 84Disruption of mindin exacerbates cardiac hypertrophy and fibrosis 85Comparative Proteomic Analysis of Differentially Expressed Proteins between Peripheral Sensory and Motor Nerves 86Slow skeletal muscle myosin binding protein-C (MyBPC1) mediates recruitment of muscle type creatine kinase (CK) to myosin.87Metallothioneins Protect Cytosolic Creatine kinases Against Stress Induced by Nitrogen-Based Oxidants 88Silencing of hHS6ST2 inhibits progression of pancreatic cancer through inhibition of Notch signaling 89Omega-3 docosahexaenoic acid and procyanidins inhibit cyclooxygenase activity and attenuate NF-κB activation through a p105/p50 regulatory mechanism in macrophage inflammation 90Up regulated miR 17 promotes cell proliferation, tumor growth and cell cycle progression by targeting RND3 tumor suppressor gene in colorectal carcinoma 91The preparation of functionalized graphene oxide for targeted intracellular delivery of siRNA 92Human urinary kallidinogenase suppresses cerebral inflammation in experimental stroke and downregulates nuclear factor-κB 93Riccardin D-26, a synthesized macrocyclic bisbibenzyl compound, inhibits human oral squamous carcinoma cells KB and KB/VCR: In vitro and in vivo studies 94ERK-MAPK Signaling Opposes Rho-Kinase to Reduce Cardiomyocyte Apoptosis in Heart Ischemic Preconditioning 95Defects in cytokine-mediated neuroprotective glial responses to excitotoxic hippocampal injury in senescence-accelerated mouse 96Targeted mutation of Fas ligand gene attenuates brain inflammation in experimental stroke 97Comparing the effects of nano-sized sugarcane fiber with cellulose and psyllium on hepatic cellular signaling in mice 98Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy 99Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells 100Up-regulating ribonuclease inhibitor inhibited epithelial-to-mesenchymal transitionand metastasis in murine melanoma cells101Small interfering RNA targeting integrin-linked kinase inhibited the growth and induced apoptosis in human bladder cancer cells102H1, a derivative of Tetrandrine, exerts anti-MDR activity by initiating intrinsic apoptosis pathway and inhibiting the activation of Erk1/2 and Akt1/2103MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer104Opsin3 sensitizes hepatocellular carcinoma cells to 5-fluorouracil treatment by regulating the apoptotic pathway105SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial–mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway106Inhibition of activated Stat3 reverses drug resistance to chemotherapeutic agents in gastric cancer cells107Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo108LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells109Identification of urinary Gc-globulin as a novel biomarker for bladder cancer by two-dimensional fluorescent differential gel electrophoresis (2D-DIGE)110HnRNPL as a key factor in spermatogenesis: Lesson from functional proteomic studies of azoospermia patients with sertoli cell only syndrome （0）111Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF)112ERβ-Mediated Estradiol Enhances Epithelial Mesenchymal Transition of Lung Adenocarcinoma through Increasing Transcription of Midkine113LYG-202 Augments Tumor Necrosis Factor-α-induced Apoptosis Via Attenuating CK2-dependent Nuclear Factor-κB Pathway in HepG2 Cells114The use of layer-by-layer self assembled coatings of hyaluronic acid and cationized gelatin to improve the biocompatibility of poly (ethylene terephthalate) artificial ligaments for the reconstruction of anterior cruciate ligament115Negative regulation-resistant p53 variant enhances oncolytic adenoviral gene therapy116The proteomic study on cellular responses of the testes of zebrash (Danio rerio) exposed to microcystin-RR117Synchronized Activity of Organic Cation Transporter 3 (Oct3/Slc22a3) and Multidrug and Toxin Extrusion 1 (Mate1/Slc47a1) Transporter in Transplacental Passage of MPP+ in Rat118Loss of A1 Adenosine Receptor Attenuates Alpha-naphthylisothiocyanate-induced Cholestatic Liver Injury in Mice119Mitochondrial Prohibitins and Septin 9 Are Implicated in the Onset of Rat Hepatocarcinogenesis120miR-106a–mediated Malignant Transformation of Cells Induced by Anti-benzo [a] pyrene-trans-7, 8-diol-9, 10-epoxide.121Increase of Anteroventral Periventricular Kisspeptin Neurons and Generation of E2-Induced LH-Surge System in Male Rats Exposed Perinatally to Environmental Dose of Bisphenol-A.122Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population123Human Umbilical Cord Stem Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Regulating Immunoinflammation and Remyelination124Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis1255-Azacytidine Induces Cardiac Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells by Activating Extracellular Regulated Kinase （0）126Smad4 disruption accelerates keratinocyte reepithelialization in murine cutaneous wound repair 127miR-200b regulates cell migration via Zeb family during mouse palate development 128Insulin-like growth factor 1 enhances the proliferation and osteogenic differentiation of human periodontal ligament stem cells via ERK and JNK MAPK pathways 129Adenoviral-mediated RNA interference targeting URG11 inhibits growth of human hepatocellular carcinoma 130miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines 131Lymphatic endothelial cell-secreted CXCL1 stimulates lymphangiogenesis and metastasis of gastric cancer 132 A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1（0）133Chronic noise exposure causes persistence of tau hyperphosphorylation and formation of NFT tau in the rat hippocampus and prefrontal cortex 134Microcystin-LR Induces Ceramide to Regulate PP2A and Destabilize Cytoskeleton in HEK293 Cells 135Hypoxia-inducible factor 1-mediated human GATA1 induction promotes erythroid differentiation under hypoxic conditions 136p53 suppresses lung resistance-related protein expression through Y-box binding protein 1 in the MCF-7 breast tumor cell line 137Positive and negative regulation of insulin action by genistein in the endothelium 138Maternal low-protein diet causes epigenetic deregulation of HMGCR and CYP7α1 in the liver of weaning piglets 139mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo 140Investigation of elemene-induced reversal of tamoxifen resistance in MCF-7 cells through oestrogen receptor α (ERα) re-expression 141Inhibition of herpes simplex virus infection by oligomeric stilbenoids through ROS generation 142MEK1–ERKs signal cascade is required for the replication of Enterovirus 71 (EV71)143Local hyperthermia could induce antiviral activity by endogenous interferon-dependent pathway in condyloma acuminata 144Houttuynia cordata blocks HSV infection through inhibition of NF-kB activation 145Cardioprotective Effect of Paeonol and Danshensu Combination on Isoproterenol-Induced Myocardial Injury in Rats 146Evaluation of Dermal Substitute in a Novel Co-Transplantation Model with Autologous Epidermal Sheet 147RhoC Regulates the Proliferation of Gastric Cancer Cells through Interaction with IQGAP1148Luteolin Induces Carcinoma Cell Apoptosis through Binding Hsp90 to Suppress Constitutive Activation of STAT3149L-Carnitine Is an Endogenous HDAC Inhibitor Selectively Inhibiting Cancer Cell Growth In Vivo and In Vitro 150Angiotensin-(1–7) in Paraventricular Nucleus Modulates Sympathetic Activity and Cardiac Sympathetic Afferent Reflex in Renovascular Hypertensive Rats 151Silencing Prion Protein in MDA-MB-435 Breast Cancer Cells Leads to PleiotropicCellular Responses to Cytotoxic Stimuli152miR-511 and miR-1297 Inhibit Human Lung Adenocarcinoma Cell Proliferation by Targeting Oncogene TRIB2153Proteomic Analysis of Adrenocorticotropic Hormone Treatment of an Infantile Spasm Model Induced by NMethyl-D-Aspartic Acid and Prenatal Stress154MicroRNA-145 Protects Cardiomyocytes against Hydrogen Peroxide (H2O2)-Induced Apoptosis through Targeting the Mitochondria Apoptotic Pathway155Berberine Reduces Fibronectin Expression by Suppressing the S1P-S1P2 Receptor Pathway in Experimental Diabetic Nephropathy Models156Transcriptional Regulation of PES1 Expression by c-Jun in Colon Cancer157Orphan Nuclear Receptor Nur77 Regulates Androgen Receptor Gene Expression in Mouse Ovary158Inhibition of Soluble Epoxide Hydrolase Attenuates High-Fat-Diet–Induced Hepatic Steatosis by Reduced Systemic Inflammatory Status in Mice159l-Tetrahydropalmatine, an Active Component of Corydalis yanhusuo W.T. Wang, Protects against Myocardial Ischaemia-Reperfusion Injury in Rats160Retigeric Acid B Exhibits Antitumor Activity through Suppression of Nuclear Factor-kB Signaling in Prostate Cancer Cells in Vitro and in Vivo161Dvl2-Dependent Activation of Daam1 and RhoA Regulates Wnt5a-Induced Breast Cancer Cell Migration162Temporal Dissection of K-rasG12D Mutant In Vitro and In Vivo Using a Regulatable K-rasG12D Mouse Allele163Interplay between Cell Migration and Neurite Outgrowth Determines SH2B1b-Enhanced Neurite Regeneration of Differentiated PC12 Cells164JWA Deficiency Suppresses Dimethylbenz[a]Anthracene-Phorbol Ester Induced Skin Papillomas via Inactivation ofMAPK Pathway in Mice165MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1166Gu-4 Suppresses Affinity and Avidity Modulation of CD11b and Improves the Outcome of Mice with Endotoxemia and Sepsis167CD36 Participates in PrP106–126-Induced Activation of Microglia168HGF-Induced PKCf Activation Increases Functional CXCR4 Expression in Human Breast Cancer Cells169MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R170LRP16 Integrates into NF-kB Transcriptional Complex and Is Required for Its Functional Activation17117b-Estradiol Enhances the Response of Plasmacytoid Dendritic Cell to CpG172Anticancer Activity of 2α, 3α, 19β, 23β-Tetrahydroxyurs-12-en-28-oic Acid (THA), a Novel Triterpenoid Isolated from Sinojackia sarcocarpa173SHP-2 Promotes the Maturation of Oligodendrocyte Precursor Cells Through Akt and ERK1/2 Signaling In Vitro174Generation of Germline-Competent Rat Induced Pluripotent Stem Cells175Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Cytotoxicity and Inflammation in HaCaT Cells through Inhibition of ROS/NF-kB/COX-2 Pathway176Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Injury by Inhibiting ROS-Activated ERK1/2 and p38MAPK Signaling Pathways in PC12 Cells177Probiotic-Derived Polyphosphate Enhances the Epithelial Barrier Function and Maintains Intestinal Homeostasis through Integrin–p38 MAPK Pathway178STAT3 Knockdown Reduces Pancreatic Cancer Cell Invasiveness and Matrix Metalloproteinase-7 Expression in Nude Mice179GSK3 Inhibitor-BIO Regulates Proliferation of Immortalized Pancreatic Mesenchymal Stem Cells (iPMSCs)180SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress 181Hyperdopaminergic Modulation of Inhibitory Transmission Is Dependent on GSK-3βSignaling-Mediated Trafficking of GABAA Receptors 182 A natural coumarin derivative esculetin offers neuroprotection on cerebral ischemia/reperfusion injury in mice 183Administration of embryonic stem cells generates eVective antitumor immunity in mice with minor and heavy tumor load 184Curcumin inhibits tumor proliferation induced by neutrophil elastase through the upregulation of α1-antitrypsin in lung cancer 185ROCK1 induces ERK nuclear translocation in PDGF-BB-stimulated migration of rat vascular smooth muscle cells 186NPA Motifs Play a Key Role in Plasma Membrane Targeting of Aquaporin-4187PI3K/Akt-dependent phosphorylation of GSK3β and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration 188Beclin 1-mediated autophagy in hepatocellular carcinoma cells: Implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling 189Raft coalescence and FcγRIIA activation upon sphingomyelin clustering induced by lysenin 190Inhibition of Aβ25–35-induced cell apoptosis by Low-power-laser-irradiation (LPLI)through promoting Akt-dependent YAP cytoplasmic translocation 191Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells 192BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats （0）193High Expression of Proline-Rich Tyrosine Kinase2 is Associated with Poor Survival of Hepatocellular Carcinoma via Regulating Phosphatidylinositol 3-Kinase/AKT Pathway 194Effects of DEHP on endometrial receptivity and embryo implantation in pregnant mice 195Inhibition of FAK prevents blister formation in the neonatal mouse model of pemphigus vulgaris 196Mechanisms involved in extraterritorial facial pain following cervical spinal nerve injury in rats 197Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways 198XJP-1, a novel ACEI, with anti-inflammatory properties in HUVECs 199Tsukushi controls the hair cycle by regulating TGF-β1 signaling 200Synchronous detection of miRNAs, their targets and downstream proteins in transferred FFPE sections: applications in clinical and basic research 201Hypoxia-inducible Factor Activation in Myeloid Cells Contributes to the Development of Liver Fibrosis in Cholestatic Mice 202proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells.203Monoclonal antibody to six transmembrane epithelial antigen of prostate-4 influences insulin sensitivity by attenuating phosphorylation of P13K (P85) and Akt: Possiblemitochondrial mechanism204YAP accelerates Aβ25–35-induced apoptosis through upregulation of Bax expression by interaction with p73205JWA enhances As2O3-induced tubulin polymerization and apoptosis via p38 in HeLa and MCF-7 cells2062,5-Hexanedione induces human ovarian granulosa cell apoptosis through BCL-2, BAX, and CASPASE-3 signaling pathways207Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains.（0）208The differential regulation of Gap43 gene in the neuronal differentiation of P19 cells209Intracavernous transplantation of bone marrow-derived mesenchymal stem cells restores erectile function of streptozocin-induced diabetic rats（0）210Leukotriene D4 induces cognitive impairment through enhancement of CysLT1R-mediated amyloid-β generation in mice211DHEA prevents A 25e35-impaired survival of newborn neurons in the dentate gyrus through a modulation of PI3K-Akt-mTOR signaling212Glucose oxidase induces insulin resistance via influencing multiple targets in vitro and in vivo: The central role of oxidative stress213Puerarin attenuates endothelial insulin resistance through inhibition of inflammatory response in an IKKβ/IRS-1-dependent manner214Luteolin inhibits inflammatory response and improves insulin sensitivity in the endothelium215Resveratrolmodulatesadipokineexpressionandimprovesinsulinsensitivity in adipocytes: Relative to inhibition of inflammatory responses216Aquaporin-4 mediates astrocyte response to β-amyloid217A Novel Therapeutic Vaccine of Mouse GM-CSF Surface Modified MB49 Cells Against Metastatic Bladder Cancer （0）218miR-21 as an Independent Biochemical Recurrence Predictor and Potential Therapeutic Target for Prostate Cancer （0）219Maternal-restraint stress increases oocyte aneuploidy by impairing metaphase I spindle assembly and reducing spindle assembly checkpoint proteins in Mice220Aberrant expression of chemokine receptor CCR4 in human gastric cancer contributes to tumor-induced immunosuppression (0)221Prophylactic lithium alleviates postoperative cognition impairment by phosphorylating hippocampal glycogen synthase kinase-3β (Ser9) in aged rats222Cytochrome P450 dysregulations in thioacetamide induced liver cirrhosis in rats and the counteracting effects of hepatoprotective agents223Upregulation of Nestin in Proximal Tubules may Participate in Cell Migration during Renal Repair224Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney.（0）225Probing the difference between BH3 groove of Mcl-1 and Bcl-2 protein: Implications for dual inhibitors design22620(S)-Ginsenoside Rh2 Noncompetitively Inhibits P-Glycoprotein In Vitro and In Vivo: A Case for Herb-Drug Interactions227Thioacetamide Intoxication Triggers Transcriptional Upregulation but Enzyme Inactivation of UDP-glucuronosyltransferases（0）228Baicalein, a natural product, selectively activating AMPKα2 and ameliorates metabolic disorder in diet-induced mice229Gankyrin gene deletion followed by proteomic analysis: insight into the roles of Gankyrin in Tumorigenesis and Metastasis 230Angiotensin II increases CTGF expression via MAPKs/TGF-β1/TRAF6 pathway in atrial fibroblasts 231Microvillous cells expressing IP3 receptor type 3 in the olfactory epithelium of mice 232Plasma Membrane H+-ATPase and 14-3-3 Isoforms of Arabidopsis Leaves:Evidence for Isoform Specificity in the 14-3-3/H+ -ATPase Interaction 233 A mechanism for abnormal angiogenesis in human radiation proctitis: analysis of expression profile for angiogenic factors 234Induction and Mechanism of Apoptosis by Hydroxycamptothecin in Human Tenon's Capsule Fibroblasts 235Adiponectin inhibits KISS1 gene transcription through AMPK and specificity protein-1 in the hypothalamic GT1-7 neurons 236Taurine attenuates lipopolysaccharide-induced disfunction in mouse mammary epithelial cells 237Phycocyanin may suppress d-galactose-induced human lens epithelial cell apoptosis through mitochondrial and unfolded protein response pathways 238Activation of the unfolded protein response contributed to the selective cytotoxicity of oroxylin A in human hepatocellular carcinoma HepG2 cells 239The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cells in vitro 240 E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells 241Oroxylin A inhibits matrix metalloproteinase-2/9 expression and activation by up-regulating tissue inhibitor of metalloproteinase-2 and suppressing the ERK1/2signaling pathway 242Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myocardial infarction: Role of TGF-β1-TAK1243The hormesis effect of BDE-47 in HepG2 cells and the potential molecular mechanism 244Involvement of p120 in LPS-induced NF- B activation and IL-8 production in human bronchial epithelial cells 245Involvement of JNK and P53 Activation in G2/M Cell Cycle Arrest and Apoptosis induced by Titanium Dioxide Nanoparticles in neuron cells 246The role of miR-506 in transformed 16HBE cells induced by anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide 247Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells 248Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-kB activation 249Hypoxic preconditioning induces neuroprotection against transient global ischemia in adult rats via preserving the activity of Na+/K+-ATPase 250(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death 251Cdk1 interplays with Oct4 to repress differentiation of embryonic stem cells into trophectoderm 252MicroRNA-133b Inhibits the Growth of Non-small Cell Lung Cancer by Targeting the Epidermal Growth Factor Receptor 253MicroRNA-145 suppresses mouse granulosa cell proliferation by targeting activin receptor IB 254Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer bytargeting ILK。