A status report on research in transparent informed prefetching
英汉句子基本结构的逻辑关系的比较与翻译

湖南师范大学硕士学位论文英汉句子基本结构的逻辑关系的比姓名:***申请学位级别:硕士专业:英语语言文学指导教师:***20011001摘要f语言是人类认知现实,进行交流的工具。
我们每天使用语言,我们蛀活在一个语言文字的世界里,时时刻刻都有人在说话、写字或阅读。
语言对人类来说实在是不可缺的,我们的生活越来越有赖于正确而高效地运用语言。
这就是语言的共性(普遍性)。
但我们知道世界上有上千种语言,不同的民族使用的是不同的语言,这就是语言的个性(特殊性)。
语言的差异并没有给人类的交流带来障碍,在人类的成功交流的后面是什么在起作用?这就是撰写本文的目的。
、夕撰并极其语义表现的一致性来探索语言的普遍性及其人类的翻译活动的可译性和忠实性。
f人是有理性的,思维是每一个具有正常大脑的人都有的一种能力,、具有全人类的性质。
思维是理性的、抽象的,语言是思维的物质外壳,是思维的表现形式,是反映人类思维过程和客观实际的。
大量的研究事实证明:说不同语言的人地们对客观世界的认知,如果正确的话,是没有什么差异的。
无论何种肤色或何种民族的人,他们的逻辑思维必须反映事物的客观规律性,砝客卿疼姆的认识才会有统一性,不同民族的语言交流才能成功:j’’~属维的共性使得“普遍语法”存在于人脑中,表现了人类语言的实质,反映了人在掌握语言过莽起够具有的一个普遍共同的基础。
这就是语言共性论的基础。
吵/f,我们首先阐述了当代美国著名语言学家chomsky的观点,他根据普遍语法创立了转换生成语法(TG语法)。
按照转换生成语法理论来分析,句子的基本句型是由NP十VP(即:s—NP+vP)的基本结构构成。
每个句子有两种结构:即表层结构和深层结构。
一个句子从深层结构到表层结构的转换意味着从内容到形式的转换。
句子的形式是由句子的表层结构表达的,句子的意义是由其深层结构表达的。
表层结构反映语言的差异性,深层结构反映语言的相似性。
一个句子的语义表现(即:一个命题)是语义规则在深层结构的运过程)以及这个过程中参与者(施事和受事)、属性、环境之间的关系。
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《中西医结合护理》2022年8卷4期封面-目录页-封底

目次2022年4月第8卷第4期中西医结合老年慢病及管理专栏聚焦新时代老年慢病护理及管理——“中西医结合老年慢病及管理”专栏导读………………………………………………………………………邱丽艳(1)延续性护理对老年慢性病患者用药安全的影响………………………………………王华新,戴晖,唐玲,赵佳璐(2)PDCA 循环在提高老年介入治疗患者术后健康宣教知晓率中的作用………………………………………郭慧慧,邢英,金悦,方蕊(6)提高泌尿外科手术患者深静脉血栓形成预防措施落实率的品管圈实践………仇德媛,段俊芳,栗平,秦晓翠,王惠惠,张莹莹,陈孟涵(11)集束化护理预防脑出血手术患者下肢深静脉血栓形成的效果………………………………………………………………………时艳华(15)运用思维导图模式提升呼吸内科危重症患者护理交接班质量………………………………………………………………………王芳(18)有氧运动在2型糖尿病辅助治疗中的应用…………………………………………………许媛,冷梅,贾楠(22)中医护理技术在社区护理中的应用现状及思考……………………………张丽君,曹蕾,鄂海燕,唐玲,郑乃花(26)基于“互联网+”的医院-社区-家庭合作型护理服务模式的研究进展…………………………………………………冷梅,李齐,贾楠(31)呼吸训练在慢性阻塞性肺疾病稳定期患者中的应用进展………………………………………………………………………杨蕊(36)护理门诊人文关怀和护患沟通技巧浅谈………………………………………………………………………刘丹(41)论著老年脑卒中患者注意力水平现状及影响因素研究………………………李赛赛,李茹雪,周然,成杰,李安奕,梁亚静(44)基于格林模式的健康教育在肺癌患者围手术期功能锻炼中应用………………………………………………………………………蔡道玲(50)睡眠治疗仪辅助治疗老年睡眠障碍临床观察……………………………………………………吴念,凌慧芬,陈曦(56)中医特色护理皮内针联合耳穴压豆治疗复发性口腔溃疡的效果观察…………………………………………朱玉华,朱凤,李逗逗,孙贵凤(60)1例系统性红斑狼疮致动眼神经麻痹患者护理体会…………………………………李运翠,唐玲,胡海荣,彭丹,綦文婧(63)中医护理技术在膝关节置换术后疼痛干预中的应用进展……………………………………………………………柳菲,闫秋艳(67)ZHONGXIYI JIHEHULI主办单位中华中西医结合护理学会北京市中医护理能力提升工程办公室编辑《中西医结合护理》编辑部主编唐玲主任黄磊编辑尹佳杰吴银平编辑助理鄂海燕美术编辑王丽地址南京市龙蟠路155号联合立方广场3⁃203邮编210037电话************邮箱bjb@出版中西医结合护理杂志社社长叶振华电话************网刊http ://邮箱tg@学术推广上海乐护文化传播有限公司电话021-********本刊刊出所有文章不代表编委会以及编辑部的观点ZHONGXIYI JIHE HULI2022年4月第8卷第4期技术与方法空气闭锁肌肉注射法在新型冠状病毒灭活疫苗注射中的应用…………………………………………………………………………………………………郑雯,智慧(74)胃肠减压器在压力性损伤患者居家延续护理中的应用……………………………………………………………陈卓,刘娜,尤欣,孙红艳,李丹,赵春华(78)PCI术后合并室壁瘤和血栓的左心衰竭患者行左心室辅助装置植入的护理配合………………………………………………………………………………………付朝娟,夏叶松,邹秀芳(82)护理管理危重症专业小组在提升医院危重症护理水平中的作用探讨………………………………………………………………………………………彭金娥,王思懿,吴雪花(86)骨科外来器械及植入物精准配送的流程优化与效果评价………………………………………………………………………………………夏叶松,邹秀芳,付朝娟(90)低年资中医护理人员规范化培训现状与发展………………………………………………………………………………………李倩,周革霞,刘潇禹(94)案例分享基于医护患一体化模式护理盆底失弛缓综合征1例……………………………………………………………………汪佳婧,鄂海燕,魏永春,董玉霞,秦沙沙(99)1例肝肾联合移植术后并发卡氏肺孢子菌肺炎患者的护理体会………………………………………………………………………………………………居星星,于瑞(103)1例糖尿病合并阿尔兹海默症患者压疮护理体会…………………………………………………张艺璇,王春红,侯妮娜,徐卫红,赵欣,刘欢,唐玲(106)1例川崎病并发急性心肌梗死患者的护理体会………………………………………………………………………………………………罗芳,宋咪(110)综述体动记录仪与多导睡眠监测仪在睡眠监测应用中的一致性研究进展……………………………………………………………………………毛嘉欣,徐林燕,张艳萍,蒋梅艳(112)回顾护士在糖尿病足预防和护理中的作用…甘露,谢薇,刘青,江永红,袁铮,肖孟云,莫梅,袁丹,陈红伊,江青霞,徐腾飞,李秋林(117)行为阶段转变理论在护士标准防护中的应用研究进展…………………………………………………………………………………………………………尹红梅(121)系统性红斑狼疮患者焦虑抑郁的相关影响因素研究进展……………………………………………………………………………马海燕,王霞,张利娟,万青(126)Volume 8Number 4April 2022Focusing on the chronic disease management and nursing for the elderly in the new era ………………………………………………QIU Liyan (1)Effect of continuous nursing intervention on medication safety in elderly pa⁃tients with chronic diseases ……………WANG Huaxin ,DAI Hui ,TANG Ling ,ZHAO Jialu (2)Application of PDCA cycle in improving the awareness of postoperative health education among elderly patients with interventional therapy …………………GUO Huihui ,XING Ying ,JIN Yue ,FANG Rui (6)Application of quality control circle activities to improve the implementa⁃tion rate of prevention on deep venous thrombosis in patients undergo⁃ing urological surgery ………………QIU Deyuan ,DUAN Junfang ,LI Ping ,QIN Xiaocui ,WANG Huihui ,ZHANG Yingying ,CHEN Menghan (11)Effect of bundled care on prevention of lower extremity deep venous throm⁃bosis in patients undergoing surgery for cerebral hemorrhage ………………………………………………………SHI Yanhua (15)Application of the mind map mode in the quality improvement of nursing handovers for critically ill patients with respiratory diseases ………………………………………………………WANG Fang (18)The adjunctive effect of aerobic exercise in the treatment of type 2diabetes …………………………………XU Yuan ,LENG Mei ,JIA Nan (22)Application status and thinking of Traditional Chinese Medicine nursing technology in community -based nursing …………………………………ZHANG Lijun ,CAO Lei ,E haiyan ,TANG Ling ,ZHEN Naihua (26)Research progress on the Internet Plus -based hospital -community -family collaborative nursing service model ………………………………………LENG Mei ,LI Qi ,JIA Nan (31)Research progress of respiratory rehabilitation training in patients with sta⁃ble chronic obstructive pulmonary disease ……………YANG Rui (36)Humanistic care and nurse -patient communication in the nursing clinic …………………………………………………………LIU Dan (41)Analysis of current status and influencing factors of elderly stroke patients'attention ……………LI Saisai ,LI Ruxue ,ZHOU Ran ,CHENG Jie ,LI Anyi ,LIANG Yajing (44)Health education based on precede -proceed model in perioperative function⁃al exercise for patients with lung cancer ……………CAI Daoling (50)Clinical observation of sleep therapy instrument in the treatment of sleep dis⁃orders in the elderly …………WU Nian ,NING Huifen ,CHEN Xi (56)Effect of intradermal acupuncture combined with auricular acupoint pressingin the treatment of recurrent oral ulcers……………ZHU Yuhua ,ZHU Feng ,LI Doudou ,SUN Guifeng (60)Contents SponsorAssociationofIntegrativeNursingBeijing Traditional Chinese Med⁃icine Nursing Competence Im⁃provement Project OfficeEiditingEditorial Board of Chinese Jour⁃nal of Integrative Nursing Editor-in-ChiefTANG Ling DirectorHUANG Lei EditorsYIN Jiajie WU Yinping Editorial Assistant E Haiyan Art Editor WANG Li Address NO.155,LongpanRoad ,Nanjing ,China Post Code 210037Tel +86-25-85552880E⁃mail :bjb@PublisherIntegrative Nursing Press Founder and CEO YE Zhenhua Tel +86-25-85630967Online Publishinghttp ://E⁃mail :tg@Academic PromotionShanghai Lehu Media Co.,Ltd Tel +86-21-31262772Volume8Number4April2022Nursing management of a patient with oculomotor nerve paralysis caused by systemic lupus erythematosus ………………………………………LI Yuncui,TANG Ling,HU Hairong,PENG Dan,QI Wenjing(63)Application progress of Traditional Chinese Medicine nursing technology in pain control after total knee arthroplasty ……………………………………………………………………………………LIU Fei,YAN Qiuyan(67)Application of air-lock method in the deltoid intramuscular injection of COVID-19vaccine…………………………………………………………………………………ZHENG Wen,ZHI Hui(74)Application of the gastrointestinal decompression device in home-based continuing care of patients with pressure injury …………………………CHEN Zhuo,LIU Na,YOU Xin,SUN Hongyan,LI Dan,ZHAO Chunhua(78)Nursing cooperation in left ventricular assist device implantation for a patient with ventricular aneurysm and thrombus after percutaneous coronary intervention………FU Chaojuan,XIA Yesong,ZOU Xiufang(82)Role of the professional critical care team in improving the quality of critical care in the hospital …………………………………………………………………PENG Jine,WANG Siyi,WU Xuehua(86)Optimization and evaluation of precision distribution of loaned instruments and implants for orthopedic surgery ………………………………………………………………XIA Yesong,ZOU Xiufang,FU Chaojuan(90)The present situation and development of standardized training for the Traditional Chinese Medicine nursing staff with low seniority……………………………………………LI Qian,ZHOU Gexia,LIU Xiaoyu(94)Application of doctor-nurse-patient integration mode in nursing of a patient with anismus………………………………WANG Jiajing,E Haiyan,WEI Yongchun,DONG Yuxia,QIN Shasha(99)Nursing management of a patient with Pneumocystis carinii pneumonia after combined liver and kidney trans⁃plantation…………………………………………………………………………JU Xingxing,YU Rui(103)Nursing management of pressure ulcers in a patient with diabetes and Alzheimer’s disease……………………………………………ZHANG Yixuan,WANG Chunhong,HOU Nina,XU Weihong,ZHAO Xin,LIU Huan,TANG Ling(106)Nursing management of a patient with kawasaki disease complicated with acute myocardial infarction …………………………………………………………………………………LUO Fang,SONG Mi(110)Research progress of consistency between actigraphy and polysomnography in sleep monitoring …………………………………………MAO Jiaxin,XU Linyan,ZHANG Yanping,JIANG Meiyan(112)Role of nurses in prevention and nursing of diabetic foot disease…………………………GAN Lu,XIE Wei,LIU Qing,JIANG Yonghong,YUAN Zheng,XIAO Mengyun,MO Mei,YUAN Dan,CHEN Hongyi,JIANG Qingxia,XU Tengfei,LIU Qiulin(117)Research progress on application of the trans-theoretical model and stages of change in standard precautions among nurses……………………………………………………………………………YIN Hongmei(121)Research progress of anxiety and depression in patients with systemic lupus erythematosus…………………………………………………MA Haiyan,WANG Xia,ZHANG Lijuan,WAN Qin(126)。
2023年大学英语三级模拟真题

大学英语三级(B)真题2023年06月Part ⅠListening ComprehensionDirections.Thi.par.i.t.tes.you.listenin.ability.I.consist.o..sections.1.A.Let'.hav..break.. B.Thi.way.please..C.Don'.mentio.it. D.No.than.you.2.A.O.Monday... B.Joh.Smith... C.Tak.i.easy.....D.It'te.3.A.Ho.d.yo.do.... B.I.doesn'.matter. C.Yes.please... D.Min.you.step.4.A.I'.afrai.not......B.Neve.mind.. C.Hurr.up... D.Hav..goo.time.5.A.G.ahead.please... B.Yes..am. C.I'.lov.to..... D.He'.fro.China.6.A.Oh..see........B.Her.i.is. C.It'.ove.there....D.Yes.o.course.7.A.G.on.please....B.Tw.dollars... C.Sure..will.....D.Her.yo.are.Section B8.A.Abou.15.year.ago...........B.Abou.12.year.ago.. C.Abou.11.year.ago.......... D.Abou.10.year.ago.9.A.Boring................ B.Difficult.. C.Interesting...............D.Satisfactory.10.A.It.location.............. B.It.development...C.It.population.............D.It.history.11.A.I.i.modem............. B.I.i.crowded...C.I.i.small..............D.I.i.quiet.12.A.Sh.i.i.poo.health..........B.Sh.faile..test...C.Sh.hasn'.enoug.money........D.Sh.hasn'.go.an.offer.13.A.Sho.hi.I.card...........B.Fil.i..form...C.Writ..report............. D.Pa.som.money.14.A.Sh.ha.he.le.broken......... B.Sh.fel.fro..bicycle...C.Sh.feel..bac.pain..........D.Sh.ha.go..headache.Section C15.A.A.apartmen.wit..goo.view..... B.A.apartmen.o.two-bedrooms...C.A.apartmen.o.th.groun.floor.... D.A.apartmen.wit.centra.heating.16.A.Nea..subwa.station......... B.Nea..hotel...C.I.th.downtown............D.I.th.suburbs.17.A.T.hav.bette.opportunities.......B.T.improv.hi.skills...C.T.wor.fewe.hours..........D.T.ge..highe.salary.18.A.Fo.si.years..............B.Fo.fiv.years...C.Fo.thre.year.............D.Fo.tw.years.19.A..professor.............. B..manager...C.A.engineer..............D..designer.Section Dpany..woul.lik.t.sa."Than.yo.fo. 2..u.t.suc..wonderfu.p arty"..thin.th.musi.i. 2. .th.foo.an.win.ar.ver.nice.an.th.peopl.her.ar.al.ver.kind.Als.we'v.enjoye. meetin.an. fortabl.tim.together.W.hav.reall.enjoye.ourselves..hop.w.wil.b.a bl.t.maintai.th. 2..an.mak.nex.yea.anothe.grea.on.together.Than.yo.agai.fo.th.party.We'v.reall.h a. 2. .Part ⅡVocabulary and Structure25. It was not until yesterday ______ they decided to re-open the business talk...A.whe...... B.whic...... C.tha...... D.as26. We have to ______ the cost of setting up a new hospital in that area...A.wor.ou.....B.pu.o...... C.fil.u..... D.carr.on27、We need to ______ an eye on all the activities to make sure that people stay safe...A.catc...... B.kee.......C.tak...... D.bring28、The local government has always placed a strong emphasis ______ education and vocational training...A.wit.......B.fo........C.o.......D.to29、Don't take the wrong turn before you ______ the railway station...A.hav.......B.ru........C.kee...... D.reach30、The team doesn't mind ______ at weekends as long as they can finish the task...A.worke......B.workin......C.t.wor.....D.work31. We are a non-profit company ______ team members are from all over the country...A.whos......B.tha....... C.whic..... D.what32. The meeting room is so small that it can hold 20 people ______.s......B.a.firs...... C.a.mos.....D.a.once33. She gave us a detailed ______ of the local government's new health-care proposal...A.impressio.... B.explanatio.... catio.... munication34. Linda ______ her training in a joint company by the end of next month... A.finishe......B.ha.finishe.... C.ha.finishe... D.wil.hav.finished35. We were impressed by the (suggest) ______ you made at yesterday's meeting.36. The (long) ______ Charles has lived in this city, the more he likes it.37、If you want to learn some terms related to your field, you will find this book might be (help) ______.38、No one is allowed (smoke) ______ in public buildings according to the new regulation.39、The new president (ask) ______ some tough questions by the reporter in the interview yesterday.Part ⅢReading ComprehensionDirections.Thi.par.i.t.tes.you.readin.ability.Ther.ar..task.fo.yo.t.fulfill.Y o.shoul.rea.th.readin.material.carefull.an.d.th.task.a.yo.ar.instructed.Notice of Baggage Inspection (检查). T.protec.yo.an.you.fello.passengers.th.Transportatio.Securit.Administratio.(. t.inspec.al.checke.baggage.A.par.o.thi.process.som.bag.ar.opene.an.inspected.You.ba.wa.amon.t hos.selecte.fo.inspection.. Durin.th.inspection.you.ba.an.it.content.ma.hav.bee.searche.fo.prohibite.(违禁旳pleted.th.content.wer.returne.t.you.bag.. I.th.TS.securit.office.wa.unabl.t.ope.you.ba.fo.inspectio.becaus.i.wa.locked.th.office.ma.hav.b ee.force.t.brea.th.lock.o.you.bag.TS.sincerel.regret.havin.t.d.this.However.TS.i.no.responsibl.fo. damag.t.you.lock.resultin.fro.thi.necessar.securit.measures.For packing tips and suggestions on how to secure your baggage during your next trip, please visit: .gov.. ments.o.concerns.pleas.f ee.fre.t.contac.th.TS.Contac.Center.40、According to the passage, TSA is required to inspect your baggage ______...A.wit.you.writte.permissio... B.a.th.reques.o.police..C.b.airline.......... w41. According to the Notice, the purpose of the inspection is to ______...A.fin.al.overweigh.baggag...B.searc.fo.prohibite.items..C.charg.custom.dutie.....D.chec.damage.items42. After the inspection, the contents in your bag would ______...A.b.delivere.t.you.addres...B.b.give.t.yo.i.person..C.b.returne.t.you.ba.... D.b.kep.a.th.airport43. If your bag is locked, the TSA security officer may have to ______...A.brea.th.lock....... B.han.i.ove.t.police..C.giv.u.th.inspectio.... D.as.yo.t.ope.th.bag44. If the locks of your bag are damaged because of the inspection, TSA will ______... A.pa.fo.th.damag...... B.bu.yo..ne.lock.. C.no.b.responsibl.fo.i.... D.no.inspec.i.i.you.nex.tripTask 2Directions.Th.followin.i..poster.Afte.readin.it.yo.wil.fin..question.o.unfinishe.statements.number e.4.t.47.Fo.eac.questio.o.statement.ther.ar..choice.marke.A.B..an.D.Yo.shoul.mak.th.correc.choic .an.mar.th.correspondin.lette.o.th.Answe.Shee.wit..singl.lin.throug.th.center.Notes: docent (博物馆等场所旳)讲解员45. How long does the docent training program last?.. A.Fou.weeks...............B.Si.weeks... C.Eigh.weeks.............. D.Te.weeks.46. To apply for the program, you should ______... A.firs.downloa.a.applicatio.for.....B.b.goo.a.workin.wit.animals .. C.b.a.experience.publi.speake..... b47、To attend the program, you must be at least ______... A.1.year.ol....B.1.year.ol....C.1.year.ol...D.2.year.oldTask 3Directions.Th.followin.passag.i.abou..surve.conducte.b.Corvalli.Clinic.Afte.readin.it.yo.shoul.co rmatio.b.fillin.i.th.blank.marke.4.t.5.(i.n.mor.tha..words.i.th.tabl.below.Yo.shoul.wr it.you.answer.o.th.Answe.Shee.correspondingly.Than.yo.fo.selectin.th.Corvalli.Clini.(诊所.fo.you.recen.healthcar.needs.T.continu.deliverin.th.highes.possibl.leve.o.service.w.surve.ou.p ment.an.suggestion.yo.provid.abou.you.visi. wil.hel.u.evaluat.(评价.ou.service.an.improv.ou.care.. .an.t he.wil.b.kep.confidentia.(保密)..postage-pai.repl.envelop.i.enclose.fo.you.convenience.I.yo.hav.an.question.abou.thi.survey. pleas.cal.ou.Servic.Cente.a.541-754-1374.. Than.yo.fo.helpin.u.a.w.continuall.tr.ou.bes.t.improv.th.qualit.o.medica.care.Pleas.dro.you.co mplete.surve.i.th.mai.a.soo.a.possible.Patients' SurveySurvey conducted by: Corvallis ClinicAim of the survey: to deliver the highest possible level of serviceValues of patients comments and suggestions:1) helping to evaluate the clinic's 48 ;2) helping to improve the clinic's 49Promise by the clinic: comments and suggestions to be kept 50Enclosure: a 51 reply envelopeContact: to call Service Center at 52Task 4e.i.Safet.Management.Afte.readin.it.yo.ar.require.t.fin.th.it em.equivalen.t.thos.give.i.Chines.i.th.tabl.below.The.yo.shoul.mar.th.correspondin.letter.i.orde.o .th.numbere.blanks.5.throug.57.o.th.Answe.Sheet.A—Warning equipment B—Accident managementC—Protection measures D—Risk assessmentE—Administrative controls F—Detection techniqueG—Failure analysis H—Responsible personI—Harmful substances J—Protection devicesK—Accident statistics L—Safety standardsM—Accident prevention N—Monitoring systemO—Special operation P—Medical aidQ—Emergency rescue53. ______事故记录 ______检测技术54. ______报警设备 ______医疗救护55. ______有害物质 ______管理控制56. ______保护措施 ______负责人57、______特殊作业 ______失效分析Task 5plet.th.answer.tha.follo.th.q uestion.(No.5.t.No.62).Yo.shoul.writ.you.answer.(i.n.mor.tha..words.o.th.Answe.Shee.correspondingly.ITaP Instructional Lab Etiquette (守则). .i..stud.zone—municatio.device.shoul.b.turne.of.whil.insid b.. .Grou.studying—puters.* Log off from your computer—workstations left idle (空闲状态旳) for more than 10 minutes will be reset to the log-in screen.* Printouts are limited to 10-minute printing time—break large print jobs into smaller print jobs.* Customer's forms or paper are not permitted in ITaP printers—this can damage the printers,* Computers are available on a first-come-first-serve basis only during computer lab hours of operation and when no classes are scheduled in the room.58、What should you do with your cell phones while you are inside the lab?You should ______ your cell phones.59、When can you do your group studying in the lab?At ______ times.60、Why should you break large print jobs into smaller ones?Because printouts are limited to ______ printing time.61. Why are the customer's forms or paper not permitted in ITaP printers?They can ______.62. When can you use the computers in the lab?During the lab hours of ______ with no classes scheduled.Part ⅣTranslationDirections.Thi.part.numbere.6.t.67.i.t.tes.you.abilit.t.translat.Englis.int.Chinese.Eac.o.th.fou.sent ence.(No.6.t.No.66.i.followe.b.thre.choice.o.suggeste.translatio.marke.A.B.an.C.Mak.th.bes.choi c.an.writ.th.correspondin.lette.o.th.Answe.Shee.wit..singl.lin.throug.th.center.An.the.writ.you.tra nslatio.o.th.paragrap.(No.67.i.th.correspondin.spac.o.th.Translation/Compositio.Sheet.63. The healthcare and social assistant sector will account for almost a third of the job growth from 2023 to 2023.A.从2023年至2023年, 从事医疗保健工作旳员工将占社会救济业旳三分之一。
货物状态条件指南说明书

Cargo Status is the product of a cumulative process within the Integrated Cargo System that evaluates whether a consignment may be released from Customs and AQIS control.Cargo Status is determined by a set of conditions related to the cargo and associated documents. Cargo Status information is available via the Customs Interactive and is also transmitted in electronic messages to relevant stakeholders.***********************************************.auorphone1300558099This document endeavours to help users understand what needs to be done to clear their cargo when one or more of the conditions for clearance has not been met.Cargo Status is recalculated every time that an event occurs that impacts on any of the conditions including amendments to the Cargo Report and associated documents.A more comprehensive guide to Status can be found at the following link:.au/webdata/resources/files/Cargo _Status.pdfF INDING C ARGO S TATUSCargo Status is displayed on the Import Document Status Detail View screen or the Import Document Status Summary View screen. These hyperlinks are available from a number of screens depending on whether you reported the cargo or lodged an import declaration. All users can obtain access to the status screens through the:• Air Cargo Manifest List screen, • Sea Cargo Manifest List screen, or • Vessel Summary List screen.From the Import Document Status Summary View screen, click on the status condition (N or Y) next to Cargo ReportEvaluated. This takes you to the Import Document Status Detail View screen.C ARGO S TATUSAir and Sea Cargo can have a HELD status for a number of reasons. If any of the conditions relevant to the type of cargo are set to No , then the consignment will have a consolidated status of HELD.Status conditions will vary for sea cargo, depending on the type of consignment (FCX, FCL, LCL, B/B or BLK.)Supplementary Information is provided to include conditions associated with the CONDCLEAR Status.I MPORT D OCUMENT S TATUS S UMMARY V IEW S CREEN .Click on the NO next to Cargo Report Evaluated to view detailConsolidated Status is the cumulative result of Customs and Border Protection and AQIS conditions.The Import Document Status Detail View screen is displayed below. The screens for Sea and Air Cargo are slightly different as different Conditions may apply.The Consolidated status may be, HELD, CLEAR,WITHDRAWN, CONDCLEAR, TRANSIT, DCLALLOWED, SUBUBMOV, TRANSHIP, CLEARHRM, TRANSHPHRM, ACSSEIZED, AQISSEIZEDUnderbond ConditionsConditions may be applied to the Underbond Movement Request linked to the Cargo Report.Movement AllowedThe Cargo may be moved in accordance with Approved Underbond Request.NO Movement AllowedUnderbond Requests associated with this cargo have not been approved.Single Movement AllowedThe first leg in a chain of underbond movement requests has been approved. Subsequent moves are still subject to approval.H IGH L EVEL C ONDITIONS FOR ACS AND AQISCargo Report Evaluated (ACS and AQIS)This is the cumulative result of the sub conditions relating to the Cargo Report. NO indicates that one or more of any of the sub conditions have not been met.Import Declaration Evaluated (Customs and AQIS)This is the cumulative result of the sub conditions relating to the Import declaration. NO indicates that one or more of any of the sub conditions have not been met.Import Declaration PaidThe Import Declaration has not been paid.Cargo Report SACCargo Report Self Assessed Clearance. This condition indicates whether the SAC Indicator has been set to theaffirmative on the Cargo Report. If YES, an Import Declaration is not required.I MPORT D OCUMENT S TATUS D ETAILS V IEW S CREEN.The following screen is indicative only and will vary according to a number of factors, such as whether the cargo is moved by sea or air and cargo type.E XPLANATION OF ACS D ETAILED S TATUS C ONDITIONS .Evaluation CompleteIf set to NO, the Customs and Border Protection risk assessment process has not been completed.Look at the other status conditions and see which are set to NO. If this is NO, and all other conditions are YES, then the cargo is subject to border processing . This will always be NO when screening is not expired or no link is established to either an Impending Arrival Report or the Master/Ocean Bill.Impending Arrival Report ReceivedIf set to NO, the Cargo Report has not linked an Impending Arrival Report. Reasons may be, the key identifiers such as Vessel and Voyage for sea or Flight and Date for air may be incorrect on the Cargo report, the Ocean Bill/MAWB has not been reported, or the Impending Arrival Report has not been reported.Complete Underbond Series ApprovedIf this condition is set to NO, not all Underbond MovementRequests linked to the report have been approved. There must be complete series of Approved Underbond Requests from the place of Discharge to the place of Destination.Departure from Last Overseas PortIf set to NO and there is a linked Impending Arrival Report(denoted by a YES against that condition), the Vessel or Aircrafthas not departed from its last overseas port. (Departure from Last Overseas port information is obtained from the Impending Arrival Report)* It should be noted that Cargo Status will not be transmitted until the vessel or aircraft has departed its last overseas port.Screening Period ExpiredIf set to NO, the screening period is still current; Check the lodgement or amendment time of the cargo report.*It should be noted that Cargo Status will not be transmitted until the screening period or the Cargo Report has elapsed. Screening Periods;Air - 2 hours (additional 15 minutes for amendments) Sea- 24 hours (additional 2 hours for amendments)Quoted Master/Ocean Bill ExistsIf set to NO, there is no linked Ocean or Master bill. The Ocean or Master may not have been reported or has been withdrawn. Check key identifiers of Cargo Report to ensure correctness. If correct, contact shipping company or airline to ascertain why no Master/Ocean exists.Impending Arrival Report ClearedIf set to NO, Customs and Border Protection has assessed that the nature and degree of risk for this vessel or aircraft requires the holding of all cargo on board. NO will also display if the discharge indicator is set to “NO” or if the Discharge Port is not included on an Impending Arrival Report line.LCL Underbond Satisfied (This will only be displayed if the cargo type is LCL)If set to NO, there is no Underbond Request linked to the Cargo Report. Check unique identifiers on Cargo Report or check with client responsible for moving the cargo and arrange for an Underbond Request to be lodged. An underbond may be lodged but is not approved (i.e. ‘chained’)Lowest Level BillIf set to NO, another bill exists that quotes this bill as its parent, or this bill has been reported with the Freight ForwarderIndicator set as ‘Yes’. Check the Diagnostic facility to match the details. If set to NO this indicates that a lower level bill exists and that this line of cargo will never have a CLEAR status. The status for this line of cargo will only ever be SUBUBMOV or HELD. A CLEAR status can only ever be generated at the lowest level bill.AUSTRALIAN CUSTOMS SERVICE***********************************************.auorphone1300558099-2-Deconsolidated Underbond SatisfiedIf set to NO, the cargo is a part of a consolidation, and an underbond with a DCL (deconsolidation) movement reason code has not been lodged or approved. All air house waybills and sea LCL cargo require an approved DCL underbond before clearance can be given.Any parent/Sub master bills should be lodged, and their numbers quoted correctly on all lower bills.Cargo Not a ConsolidationIf set to NO, the Freight Forwarder Indicator is checked and there is a lower level bill that nominates this report as a parent.Release premises in Destination PortIf set to NO, the cargo needs to be moved to its destination port before being cleared into home consumption. In short, the Discharge and Destination Ports in Australia are different. Either there is no underbond to move this consignment to its destination port, OR the destination establishment on the underbond is not in the same state as the destination port quoted on the cargo report.Related FCX Lines Cleared.This condition is only displayed if the cargo type is FCX. (Not shown on the screen shot above)If set to NO, there is another cargo report quoting the same FCX container that is not clear.The condition will remain NO against all related reports until they are free of impediment and have a paid import declaration.I MPORT D ECLARATION E VALUATED(High Level Condition)This is the cumulative result of the sub conditions listed below. NO indicates that one or more of any of the conditions have not been met.Evaluation CompleteIf set to NO, the Customs and Border Protection risk assessment process has not been completed. Check if documents are required to be submitted.Declaration MatchedIf set to NO, there has been a Self Assessed Clearance declaration and an import declaration lodged for the same consignment. While more than one import declaration can exist for a consignment there cannot be more than one Self Assessed Clearance declaration or a mix of the two.Import Declaration PaidIf this is set to NO, the import declaration has been lodged but has not been paid or there is another unpaid import declaration for this consignment. Cargo Report SACThis condition indicates whether the SAC Indicator has been set to the affirmative on the Cargo Report. If YES, an Import Declaration is not required.AQIS S TATUS C ONDITIONSThe following AQIS status conditions relate to air cargo and sea cargo.Cargo Report Evaluated (High Level Condition)This is the cumulative result of the sub conditions list below. NO indicates that one or more of any of the conditions have not been met.Evaluation CompleteIf set to NO, the AQIS risk assessment process has not been completed.Look at the other status conditions and see which are set to NO. This will always be NO when screening is not expired or no link is established to either an Impending Arrival Report or the Master/Ocean Bill.Impending Arrival Report ClearedIf set to NO, AQIS has assessed that the nature and degree of risk for this vessel or aircraft requires the holding of all cargo on board. This can occur under the AQIS conditions with Giant African Snail (GAS) affected vessels.Import Declaration Evaluated (High Level Condition)This is the cumulative result of the sub conditions list below. NO indicates that one or more of any of the conditions have not been met.Evaluation CompleteIf set to NO, the AQIS risk assessment process has not been completed.***********************************************.auorphone1300558099。
科研情况汇报英文

科研情况汇报英文As a research scientist, I am pleased to present a comprehensive report on the current status of our research activities. This report will cover the progress we have made, the challenges we have encountered, and the future direction of our research.First and foremost, I would like to highlight the significant progress we have made in the past year. Our research team has been actively involved in several groundbreaking projects that have the potential to make a significant impact in the field of science. We have successfully published several papers in top-tier journals, presenting our innovative findings and contributing to the advancement of scientific knowledge. In addition, we have secured funding for several new research projects, which will allow us to further explore exciting research avenues.However, it is important to acknowledge the challenges we have faced along the way. Conducting cutting-edge research is not without its difficulties, and our team has encountered various obstacles that have tested our resolve. From technical challenges to resource constraints, we have had to navigate through numerous hurdles to keep our research on track. Nevertheless, our team's resilience and determination have allowed us to overcome these challenges and continue to make significant strides in our research endeavors.Looking ahead, we are excited about the future prospects of our research. We have several ongoing projects that show great promise, and we are confident that they will yield impactful results in the near future. Furthermore, we are actively exploring new collaborations and partnerships that will enable us to expand the scope of our research and leverage complementary expertise. By staying at the forefront of scientific innovation and embracing new opportunities, we are committed to making meaningful contributions to the advancement of knowledge and the betterment of society.In conclusion, I am proud to report that our research activities are thriving, despite the challenges we have faced. We are making significant progress, overcoming obstacles, and looking forward to a future filled with exciting opportunities. I am confident that ourresearch will continue to make a positive impact, and I am excited to see what the future holds for our team. Thank you for your attention, and I look forward to sharing more updates on our research in the near future.。
Endoscopicnasobi...

SUMMARYBenign recurrent intrahepatic cholestasis (BRIC) is characterised by recurrent episodes of jaundice, severe pruritus and low or normal serum γ-glutamyltransferase activity lasting from several weeks to months. BRIC is an autosomal recessive disorder caused by the mutation in either of the two hepatic transporter genes—ATP8B1 or ABCB11 gene. The disease is very well known for episodic flare of jaundice with cholestatic symptoms that are spontaneous or perpetuated by acute insults, followed by self-recovery. There is no proven medical therapy and rarely does it progress to progressivefamilial intrahepatic cholestasis (PFIC) or biliary cirrhosis. BRIC may be associated with nephrolithiasis, diabetes or pancreatitis. Here, we report a case of BRIC with spontaneous flare and further complicated by drug-induced liver injury with disabling cholestastic symptoms, who underwent endoscopic nasobiliary drainage and was completely relieved of the distressing symptoms.BACKGROUNDBenign recurrent intrahepatic cholestasis (BRIC) is a rare disease with frequent exacerbations whichcause distressing symptoms. Endoscopic nasobiliary drainage (ENBD) is a novel therapy which can lead to permanent resolution of the symptoms and can be the treatment of choice.CASE PRESENTATIONA 23-year-old male with no family history of jaun-dice presented with complains of intermittent jaun-dice associated with severe pruritus and clay colouredstools since 2 years. He also complained of steator-rhoea and night blindness during the episodes. The symptoms would exacerbate during periods of stress or minor illness. His symptoms would last for 4–5 months and then would be asymptomatic for 2–3 months before recurrence. He visited multiple hospi-tals and was treated with ursodeoxycholic acid, chole-styramine, high dose of hydroxyzine, rifampicin, naltrexone, but all failed to improve his symptoms. He then received complementary alternative medi-cine for 15 days leading to aggravation of the above symptoms and presented to our hospital.On examination, there were excoriation marks all over the body but predominantly distributed over palms and lower limbs. There were no signs of liver cell failure and there was no organo-megaly.INVESTIGATIONSInvestigations revealed serum bilirubin of 11.9 mg/dL with a predominant direct fraction of 6.7 mg/dL. Aspartate amiotransferase (AST) and alanine aminotransferase (ALT) were mildly elevated with AST being 77 IU/L (normal ~5–40 IU/L) and ALT of 58 IU/L (normal ~10–40 IU/L). High alkaline phosphatase of 213 IU/L (normal ~32–92 IU/L) and normal γ-glutamyltransferase (γ-GT) of 57 (normal ~7–64 IU/L) were seen. Hypoalbu-minaemia (2.8 g/L(normal ~3.5–5.5 g/L)) and prolonged INR (2.03) secondary to anorexia and steatorrhoea were seen (figure 1).Autoimmune markers, typical (HAV , HBV , HCV , HEV) and atypical hepatotropic (EBV , HSV and CMV) viral markers were negative. Serum copper and ceruloplasmin were normal. Ultrasonography revealed a normal liver echo texture and non-di-lated biliary system. Magnetic resonance cholan-giopancreatography confirmed the normal intrahe-patic and extrahepatic bile ducts (figure 2). Liver biopsy showed centrilobular cholestasis with mild inflammation and mild periportal fibrosis (figure 3).DIAGNOSISAfter ruling out all the causes of cholestatic jaun-dice and based on history of recurring jaundice andhistopathology showing intrahepatic cholestasis with preserved architecture, he was suspected tohave BRIC based on T ygstrup et al 1criteria.TREATMENTIn view of protracted course and failure of medical therapy and on the basis of limited literature, we undertook a trial of ENBD to hasten the bile drainage (figure 2). He was supplemented with vitamin K for raised INR and vitamin A orally for the symptoms.OUTCOME AND FOLLOW-UPPatient showed improvement in jaundice, itching and night blindness. Nasobiliary drainage was removed after 7 days. Patient has been asymptom-atic for five consecutive months.DISCUSSIONBRIC and progressive familial intrahepatic cholestasis (PFIC) form a part of spectrum of familial intrahepatic cholestatic disorders. The prevalence of BRIC is largely unknown but is saidCASE REPORTEndoscopic nasobiliary drainage: an effective treatment option for benign recurrent intrahepatic cholestasis (BRIC)Ashok Choudhury,1 Anand V Kulkarni,1 Bishnupriya Sahoo,2 Chhagan Bihari 31Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India 2Pediatrics, Shree Guru Gobind Singh Tricentenary University Faculty of Medicine and Health Sciences, Gurgaon, India 3Institute of Liver and Biliary Sciences, New Delhi, India Correspondence to Dr Anand V Kulkarni, a nandvk90@g mail.c om Accepted 19 April 2017to be rarer than PFIC which occurs in 1/50 000–1/100 000births.2BRIC is a rare autosomal recessive disorder characterised by repeated self-limiting episodes of severe pruritus and jaundice lasting from several weeks to months. The disease may begin in childhood or adulthood.2 It usually begins with malaise, choles-tatic jaundice with mild transaminitis and hence can be misdi-agnosed as acute viral hepatitis. The episodes can be preceded by influenza-like illness or viral gastroenteritis or drugs which act as precipitants.2 It is a benign disease as it does not lead to progressive liver dysfunction or cirrhosis but is the cause for high morbidity. The patients can be severely jaundiced and can have pruritus, steatorrhoea and weight loss. Even in the presenceof cholestasis the serum γ-glutamyltransferase activity is not elevated. The diagnostic criteria suggested by T ygstrup was the presence of episodes of pruritus and jaundice with biochemical and histological evidence of cholestasis, symptom-free intervals lasting months to years, absence of known cause of cholestasis and normal bile ducts on cholangiography, all of which were seen in our patient.1Minuk and Shaffer 3 showed that BRIC is not mediated by a circulating cholestatic agent, but rather is secondary to an intrinsic abnormality in hepatocyte bile salt secretion. BRIC can be caused by the mutation in either of the two hepatic trans-porter genes: the ATP8B1 gene, coding for familial intrahe-patic cholestasis-1 (FIC1; BRIC type 1), or the ABCB11 gene, coding for the bile salt export pump (BSEP; BRIC type 2).2 3 ATP8B1 acts as an aminophospholipid flippase. Thus, the defect in ATP8B1 reduces transport of bile acids in the liver and the gut, which results in cholestasis and watery diarrhoea. Missense mutations in ATP8B1 leads to BRIC and non-sense frameshift mutations lead to PFIC-1. BSEP is a P-glycoprotein, defect of which leads to impaired bile salt secretion, accumulation of bile salts in hepatocytes and subsequent hepatocellular injury, apop-tosis or necrosis.Histopathology in BRIC-2 shows intrahepatic cholestasis with mild inflammation but otherwise preserved normal liver architecture and no ductular reaction. In contrast, PFIC shows intracanalicular cholestasis, giant cell transformation and varying degree of fibrosis and frank cirrhosis in advanced disease. On immunohistochemistry, loss of BSEP staining is noted. However, there is substantial polymorphism in BSEP noted and hence it is not pathognomonic hallmark feature of BRIC-2 or PFIC-2.2There is no proven treatment for this disease. Various medical approaches have been tried which include ursode-oxycholic acid, corticosteroids and bile acid-binding resins but without much success.4 Rifampicin and colestimide havebeen reported to be successful in few cases. Refractory casesFigure 1 The laboratory parameters and clinical features in relation to endoscopic nasobiliary drainage (ENBD) placement. (A ) T otal serum bilirubin (mg/dL). (B ) Serum alkaline phosphatase (SAP-32-92 IU/L), gamma glutamyl transferase (GGT-7-64 IU/L). (C ) Prothrombin time-International normalised ratio (PT-INR). (D ) ENBD placement, improvement in itching, night blindness and stool colour. Dotted lineindicates—ENBD removed.Figure 2 Imaging in benign recurrent intrahepatic cholestasis. (A, B ) Magnetic resonance cholangiopancreatography imaging of the abdomen showing normal intrahepatic and extrahepatic ducts. (C )Fluoroscopic image showing nasobiliary drain.Figure 3 H&E stained section of core biopsy specimen obtained from the liver lesion. Liver biopsy showing (A and B ) portal areas with mild inflammatory infiltrate and liver parenchyma showing cholestatic features. ×200. (C ) Mild portal fibrosis highlighted by Masson's trichrome, 200.of jaundice with pruritus (for BRIC exacerbation) have been treated with albumin dialysis.5 6Surgical approach to this disabling disease includes partial biliary diversion similar to PFIC. It is effective in improving the jaundice and pruritus, but may be associated with a high inci-dence of stoma-related complications. Minimally invasive lapa-roscopic external biliary diversion is an innovative method and showed good long-term benefit without complication in paedi-atric patients as case report.7Endoscopic nasobiliary drainage is a type of transpapillaryexternal drainage wherein the distal end of the long tube is left in the bile duct and the proximal end emerges out through the nose. It is a well-established way of biliary decompression which is most often used in acute cholangitis.8 The main advantage of ENBD is the real-time monitoring of drainage status. Report of ENBD as an effective therapy has been shown in few case series and is encouraging. Some series even showed the effects to be long lasting without any further attack of jaundice even though the nasobilliary drainage is one time and usually for 1 week, for which the exact mechanism is unknown. Stapelbroek et al9 demonstrated a reduction in the total bile acid levels (100–200 μmol/L pretreatment) that get normalised by day 3 along with resolution of pruritus. The postulated mechanism behind effec-tiveness of ENBD for BRIC includes forced bile drainage, block in the enterohepatic circulation and subsequent reduction in the hydrophobic bile acid pool. But the same thing could be achieved by placing a stent as well; advantage of ENBD over a stent is not known. Plausible explanation is that the stent-medi-ated biliary drainage is internal where there can be reabsoprtion of bile acids while ENBD is external leading to rapid decline in bile acid pool. This is supported by the fact that increased levels of phospholipids other than phosphatidylcholine, particularly sphingomyelin, in the bile drained by ENBD and disruption of the phospholipid gradient.9Our patient did not undergo any genetic testing; however the long-standing history, recurrent cholestatic jaundice episode, no imaging or histological abnormality is in favour of BRIC. He had acute worsening probably due to drug-induced liver injury. He was diagnosed based on classical clinical features, liver function tests and histology. ENBD improved the symptoms as well as the quality of life. There are hardly few cases of BRIC reported from South-East Asia to achieve a successful cure of this highly morbid disease with ENBD.Contributors AC did the ENBD procedure. Framework and idea by AVK and AC. Manuscript by AVK with inputs from BS. CB provided the histopathology images. All the authors have read the manuscript and approved the final manuscript. Competing interests None declared.Patient consent Obtained.Provenance and peer review Not commissioned; externally peer reviewed.© BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.REFERENCES1 Tygstrup N, Jensen B. Intermittent intrahepatic cholestasis of unknown etiology infive young males from the Faroe Islands. Acta Med Scand 1969;185:523–30.2 Luketic VA, Shiffman ML. Benign recurrent intrahepatic cholestasis. Clin Liver Dis2004;8:133–49.3 Minuk GY, Shaffer EA. Benign recurrent intrahepatic cholestasis. evidence for anintrinsic abnormality in hepatocyte secretion. Gastroenterology 1987;93:1187–93.4 Folvik G, Hilde O, Helge GO. Benign recurrent intrahepatic cholestasis: review andlong-term follow-up of five cases. Scand J Gastroenterol 2012;47:482–8.5 Ołdakowska-Jedynak U, Jankowska I, Hartleb M, et al. Treatment of pruritus withPrometheus dialysis and absorption system in a patient with benign recurrentintrahepatic cholestasis. Hepatol Res 2014;44:E304–E308.6 Huster D, Schubert C, Achenbach H, et al. Successful clinical application ofextracorporal albumin dialysis in a patient with benign recurrent intrahepaticcholestasis (BRIC). Z Gastroenterol 2001;39(Suppl 2):13–14.7 Metzelder ML, Petersen C, Melter M, et al. Modified laparoscopic external biliarydiversion for benign recurrent intrahepatic cholestasis in obese adolescents. Pediatr Surg Int 2006;22:551–3.8 Leung JW, Chung SC, Sung JJ, et al. Urgent endoscopic drainage for acutesuppurative cholangitis. Lancet 1989;1:1307–9.9 Stapelbroek JM, van Erpecum KJ, Klomp LW, et al. Nasobiliary drainage induceslong-lasting remission in benign recurrent intrahepatic cholestasis. Hepatology2006;43:51–3.►Benign recurrent intrahepatic cholestasis, though referred as benign can lead to distraught for the patient and needs earlyclinical suspicion.►Medical management may not be successful in all.►Endoscopic nasobiliary drainage can be the treatment of choice for patients with refractory symptomsCopyright 2017 BMJ Publishing Group. All rights reserved. For permission to reuse any of this content visit /group/rights-licensing/permissions.BMJ Case Report Fellows may re-use this article for personal use and teaching without any further permission. Become a Fellow of BMJ Case Reports today and you can:►Submit as many cases as you like►Enjoy fast sympathetic peer review and rapid publication of accepted articles►Access all the published articles►Re-use any of the published material for personal use and teaching without further permission**************************************************************************Visit for more articles like this and to become a Fellow。
Web of Science

Notes: Web of Science============================================================ FN ISI Export FormatVR 1.0PT JAU Glenn, SSchofield, OKohut, JMcDonnell, JLudescher, RSeidel, DAragon, DHaskins, THandel, EHaldeman, CHeifetz, IKerfoot, JLemus, ELictenwalner, SOjanen, LRoarty, HAF Glenn, ScottSchofield, OscarKohut, JoshMcDonnell, JaniceLudescher, RichardSeidel, DenaAragon, DavidHaskins, TinaHandel, EthanHaldeman, ClintonHeifetz, IgorKerfoot, JohnLemus, ErickLictenwalner, SageOjanen, LisaRoarty, HughTI The Trans-Atlantic Slocum Glider Expeditions: A Catalyst forUndergraduate Participation in Ocean Science and TechnologySO MARINE TECHNOLOGY SOCIETY JOURNALLA EnglishDT ArticleAB Results of Office of Naval Research (ONR)- and National ScienceFoundation (NSF)-sponsored collaborative coastal science experiments using underwater gliders were reported at the E.U./U.S. Baltic Sea conference in 2006. The National Oceanic and Atmospheric Administration(NOAA) recognized the parallel educational potential and issued a trans-Atlantic challenge-modify one of the coastal gliders and fly it across the Atlantic, entraining and inspiring students along the way. Leveraging the experience of the NSF Centers for Ocean SciencesEducation Excellence, a needs assessment process guided the developmentof a new undergraduate research program based on the cognitiveapprenticeship model. The generalized model was applied to the specificopportunities provided by the trans-Atlantic challenge, involving students in every aspect of the missions. Students participated in the modifications and testing required to increase glider endurance and inthe development of the mission planning tools. Scientist and student teams conducted three long-duration missions: (1) RU15's flight from New Jersey to Nova Scotia to test the lithium batteries and ruggedized fin technology in storms, (2) RU17's first attempt at the Atlantic crossing that provided the lessons learned, and (3) RU27's successful trans-Atlantic flight a year later. Post-flight activities included development of new intuitive glider data visualization software that enabled students to analyze the glider data and compare it with ocean forecast models, enabling students to create their own new knowledge. Lessons learned include the significant gains achieved by engaging students early, encouraging them to work as teams, giving them the tools to make their own discoveries, and developing a near-peermentoring community for increasing retention and diversity. The successhas inspired an even broader vision for international glider missions, that of a gliderenabled global classroom to repeat the track of the HMSChallenger and its first scientific circumnavigation of the globe. C1 [Glenn, Scott] Rutgers State Univ, Sch Biol & Environm Sci, Inst Marine & Coastal Sci, Coastal Ocean Observat Lab, New Brunswick, NJ 08901 USA. RP Glenn, S, Rutgers State Univ, Sch Biol & Environm Sci, Inst Marine & Coastal Sci, Coastal Ocean Observat Lab, 71 Dudley Rd, New Brunswick, NJ 08901 USA.EM glenn@FU Office of Naval Research ; Rutgers alumni ; Teledyne Webb Research ; NOAA ; U.S. IOOS ; National Science Foundation ; Department of Homeland SecurityFX Slocum gliders were developed through the vision and support of the Office of Naval Research, transitioning from an engineeringdemonstration on its first deployment at sea, to a research tool used by many federal agencies, to an operational Naval asset in less than adecade. NOAA provided the challenge for the first trans-Atlantic missions. Rutgers alumni, Teledyne Webb Research, NOAA, and U.S. IOOS provided support for the build and the launch. Educational support was provided by the National Science Foundation and the Department of Homeland Security. Our partners in Spain at Puertos del Estado and Universidad de Las Palmas de Gran Canaria provided support for the recovery. These and future missions would not be possible without the direct participation and continuing interest of the Atlantic Crossing students and their international collaborators.NR 17TC 0PU MARINE TECHNOLOGY SOC INCPI COLUMBIAPA 5565 STERRETT PLACE, STE 108, COLUMBIA, MD 21044 USASN 0025-3324J9 MAR TECHNOL SOC JJI Mar. Technol. Soc. J.PD JAN-FEBPY 2011VL 45IS 1BP 52EP 67PG 16SC Engineering, Ocean; Oceanography GA 732NNUT ISI:000288192300008EREF。
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Appears in ACM Operating Systems Review, V 27(2), April, 1993, pp.21-34.A Status Report on Research in Transparent InformedPrefetchingR. Hugo Patterson†, Garth A. Gibson*, M. Satyanarayanan*†Department of Electrical and Computer Engineering*School of Computer ScienceCarnegie Mellon University, Pittsburgh P A 15213email: rhp@AbstractThis paper focuses on extending the power of caching and prefetching to reduce file readlatencies by exploiting application level hints about future I/O accesses. W e argue that systemsthat disclose high-level knowledge can transfer optimization information across moduleboundaries in a manner consistent with sound software engineering principles. Such T ranspar-ent Informed Prefetching (TIP) systems provide a technique for converting the high through-put of new technologies such as disk arrays and log-structured file systems into low latency forapplications. Our preliminary experiments show that even without a high-throughput I/O sub-system TIP yields reduced execution time of up to 30% for applications obtaining data from aremote file server and up to 13% for applications obtaining data from a single local disk. Theseexperiments indicate that greater performance benefits will be available when TIP is integratedwith low level resource management policies and highly parallel I/O subsystems such as diskarrays.1 IntroductionToday, file read latency is the most significant bottleneck for high performance input and output. Other aspects of I/O performance benefit from recent advances in disk bandwidth and throughput resulting from disk arrays [Kim86, Salem86, Livny87, Patterson88, Reddy89], and in write performance derived from buffered write-behind and the Log-structured File System [Rosenblum91]. The development of dis-tributed file systems operating over networks with diverse bandwidth [Spector89, Satyanarayanan85, Nel-son88] only exacerbates the problem. In this paper, we argue that prefetching based on application level information is a feasible and effective strategy for reducing file access read latency in both local and net-work file systems.This material is based (in part) upon work supported by the National Science Foundation under grant num-ber ECD-8907068, the Avionics Laboratory, Wright Research and Development Center, Aeronautical Sys-tems Division (AFSC), U.S. Air Force, Wright-Patterson AFB, Ohio 45433-6543 under Contract F33615-90-C-1465, ARPA Order No. 7597, an IBM Corporation Research Initiation Grant, and a Digital Equipment Corporation External Research Project Grant. The views and conclusions contained in this document arethose of the authors and should not be interpreted as representing the official policies, either expressed orimplied, of the funding agencies. The government has certain rights in this material.1This paper presents Transparent Informed Prefetching (TIP)as a powerful and flexible mecha-nism promising to reduce application execution time in two ways.1.By exposing concurrency in the I/O workload, TIP cana)service multiple I/O requests concurrently and convert the high throughput ofdisk arrays and other new peripheral technologies into low read latency,b)overlap I/O with computation or user think time, andc)optimize I/O accesses over the larger number of outstanding requests.2.With knowledge of future I/O requests, TIP can make informed cache management deci-sions that lower cache miss rates.TIP derives its power from hints given by application levels of the system that disclose future access patterns rather than advise lower-level policies or actions. Such disclosures should be made early, as soon as knowledge becomes available. Lower levels of the system use the hints to transparently prefetch data and improve resource management, but are free to ignore or defer acting upon any hint.In addition to a discussion of TIP, this paper reports the results of preliminary experiments intended to demonstrate potential benefits and obstacles of TIP. These experiments show a 13% reduction in the execution time of the make of an X windows application with ideal hints accessing a single disk, and a 20% reduction in the same program’s execution time when accessing data remotely in the Coda distrib-uted file system [Satyanarayanan90]. A second example, the grep text search for a simple pattern in 58 files stored remotely in Coda, achieves a 30% reduction in its execution time when the shell issues the command arguments as a hint in parallel with initiating the search. These results were obtained on systems with only a single disk. Greater benefits are expected on systems with the higher throughput of a disk array.Our argument in favor of TIP begins with a review of the increasingly important I/O bottleneck and existing mechanisms for combatting it. Then we introduce the TIP approach, describe its benefits and discuss its dependence on hints that disclose instead of advise. After describing our experiments and results, we give an overview of our research plans and opportunities for further study of transparent informed prefetching and finish with a discussion of related work.2 Technology Trends2.1 The I/O BottleneckIn recent years, systems researchers have begun to highlight the need for improved I/O perfor-mance. The speed of computations using only primary memory is increasing five to ten times faster than the speed with which blocks on magnetic disk can be accessed [Patterson88, Ousterhout89]. In addition, some new technologies further increase the gap between processor and I/O performance. Distributed and wide area [Cate92] file systems slow I/O with substantial network transmission and server delays. Portable computers, which frequently spin down their disks and are only weakly connected to networks, suffer addi-tional latencies [Kistler92]. Applications that depend on the massive storage of optical disk jukeboxes or robotic tape libraries must wait while the desired media is fetched and mounted. Amdahl’s Law [Amdahl67] tells us that unless I/O subsystem performance keeps pace with improvements in the rest of the system, I/O will increasingly constrain the performance of the system as a whole.234mance. As I/O latencies grow in terms of processor cycles, prefetches must begin ever farther in advance if they are to complete in time. Unfortunately, current prefetching techniques are unable to confidently infer accesses far into the future.Caching and prefetching are important and valuable techniques for reducing read latency. But, they are insufficient today, and they will not scale with processor performance. Thus, read latency remains an important problem, and it is the focus of this work.3 Transparent Informed Prefetching (TIP)To be most successful, prefetching should be based on knowledge of future I/O accesses, not infer-ences. We claim that such knowledge is often available at high levels of the system. For example, the file access patterns of many programs are determined by simple, single-flow control structures well understood by their programmers. These programmers could give hints about their programs’ accesses to the file sys-tem. Thus informed, the file system could transparently prefetch needed data and optimize resource utiliza-tion. We call this Transparent Informed Prefetching (TIP).3.1 Application ExamplesHere are a few examples of applications that could give hints to a TIP system.An example from the Unix domain is the shell expansion of ‘*’ to a list of files. For example, the command ‘grep foobar *’ says to search (grep) for all occurrences of the string ‘foobar’ in the files in the current directory. Either grep or the shell could give a hint about all of the files that grep will access.The make program orchestrates the compilation of program modules and their linking with stan-dard libraries.Make determines its actions according to a ‘makefile’ of instructions. After parsing a ‘make-file’ and checking the status of all modules to be built,make constructs a sequence of commands that it passes to a shell for execution.Make could give hints about the whole process to a TIP system.Hints for more complex, non-sequential access patterns are also possible. An example from the supercomputer domain is stride access to large matrices [Miller91]. Data base applications often can pre-dict their accesses to satisfy a query [Chou85, Stonebraker81, Selinger79].Interactive applications, too, could provide hints. For example, when a bank customer inserts their card in an automatic teller machine, a hint about the customer’s identity could be given, and the customer’s account records retrieved while the customer enters their Personal Identification Number.An important part of our research will be to expose hints in important, I/O-dependent applications. Initially, programmers will explicitly give hints. Eventually, we expect that compilers will be able to gen-erate hints automatically for a wide range of applications.3.2 The Benefits of TIPUser hints provide a TIP system with two new levers to apply to the I/O bottleneck: exposure of I/O concurrency and knowledge of future resource demands. TIP can exploit the I/O concurrency to con-vert the high throughput of new I/O technologies to the lower access latencies these new technologies can-not provide. TIP systems can exploit knowledge of future resource demands to better manage resources such as file cache buffers.In the simplest exploitation of I/O concurrency, a system can start slow I/O accesses early and overlap their latency with ongoing computation to achieve a concurrency of two. Where data is accessed over a network, it is possible to overlap disk accesses, network transmission and computation to achieve a5concurrency of three. Such concurrencies are both the goal and the limit of current prefetching techniques. As processors get faster, the computation time available to overlap with I/O shrinks, making it harder to achieve even these modest concurrencies. TIP can ease the problem by providing more reliable informa-tion about what to prefetch farther in advance, giving the system more time to prefetch. Interactive applica-tions may even be able to give hints based on user actions that allow TIP to overlap I/O with a large amount (by computer standards) of user think time.The greatest benefit of TIP comes when there is not much time to prefetch. Where applications dribble requests one at a time into the I/O subsystem, hints can inform the system of access patterns for whole files or even multiple files. Thus, hints can expose the concurrency of many I/O requests. On sys-tems with disk arrays, TIP can service these requests with a concurrency bounded only by the number of disks in the array, potentially tens or hundreds instead of two or three. All of the files for the grep example could be retrieved concurrently. The application may not be spared the latency of the first access, but the latency of all subsequent requests will be masked behind that first access. The challenge becomes one of delivering data to the file cache as fast as the application consumes it. Thus, TIP uses the I/O concurrency that hints expose to convert the read latency problem into a read throughput problem in a manner analo-gous to the way write buffers work. TIP systems can use RAID throughput to provide low read latency. Conversely, for workloads characterized by small, serial I/O accesses that are otherwise unable to take advantage of disk arrays, TIP can use the lever of I/O concurrency to fully exploit the high throughput of RAIDs.As a side effect of concurrent prefetching, TIP fills normally short I/O queues with prefetch requests. This creates new opportunities for storage subsystem optimizations. Deep queues of prefetch requests will not encumber demand requests with queuing delays if demand requests have higher priority. For disks, deeper queues allow better arm and rotation scheduling [Seltzer90]. For network I/O, multiple prefetch requests can be batched together, reducing network and protocol processing overhead. In both cases, deeper queues increase throughput that TIP uses to reduce read latency and application execution time.Finally, TIP uses its knowledge of future I/O requests to improve cache management and reduce cache miss ratios. It is often possible to outperform an LRU page replacement algorithm, even without prefetching [Chou85, Korner90]. Unneeded blocks can be released early and needed blocks can be held longer. For example, knowing that a large file will be read sequentially twice, a TIP cache manager could hold onto the first few blocks of the file for use at the start of the second access while immediately flushing others and reusing the buffers for further prefetching. This strategy would minimize the amount of other data that is flushed from the cache.3.3 Hints for TIPAs the previous section shows, TIP is much more than simple prefetching; it is a strategy for opti-mizing I/O. Powerful optimizations such as these require TIP to be applied where detailed knowledge of the system’s static and dynamic state is available. The special advantage of TIP, however, comes from the additional power provided by high-level knowledge of future I/O activity. Therefore, application hints to TIP should disclose knowledge of high-level behavior rather than give advice about low-level resource policy decisions.67demonstrating the potential benefits and obstacles of informed prefetching. Our goals with these experi-ments were to validate TIP as a tool for reducing read latency, to determine if more than a simple, user-level mechanism is needed, to uncover implementation problems, and to develop experience incorporating hints into applications.Our experiments evaluated TIP for accesses both to a local disk and over a network to the Coda distributed file system [Satyanarayanan90]. In both cases, there was only a single request server, either a local disk or a remote file server. This fact limited the potential benefits we could expect to achieve because there was little or no opportunity for concurrency in the I/O subsystem. In addition, since the prefetching was carried out at the user level, there was no opportunity for cache management gains and lit-tle opportunity for I/O subsystem optimizations. Our results are thus conservative with respect to what could be realized by a full-fledged TIP system. In the experiments we describe below, virtually all benefits came from overlapping computation and I/O. The maximum benefit from such prefetching is a 50% reduc-tion in execution time, and this is only possible when, without prefetching, an application spends exactly 50% of its time computing without overlapping any I/O, and with prefetching, it completely overlaps I/O and computation. Thus, while we expect to see significant reductions in execution time, the rarity of ide-ally balanced applications limits these reductions to well under 50%.4.1 Test DescriptionWe used two hardware platforms for our tests. The local disk tests were conducted on a Sun Sparc-station 2 running Mach/BSD Unix 4.3. The remote tests were run on two Decstation 5000/200 also running Mach, one of them the client, and the other the server for the Coda File System. Coda is a descendent of the Andrew File System [Satyanarayanan85], but with enhancements for availability and mobility. In this sys-tem, whole files are transferred to requesting client machines which then cache them on local disks. Reads and writes are applied through the client’s buffer cache to its local disks’ copy. Writes are transferred back to the server when the file is closed.Our experiments concentrate on two applications, a make program doing a program build, and the Unix shell expanding ‘*’ to a list of files. Figure 1 shows the control flow in these experiments. In both experiments, a separate user-level process prefetched files while the program under test ran unmodified in its own process.Figure 1a, on the left, illustrates the shell experiments. A wrapper program, called hcsh for hint-csh, handles the prefetching. The experimenter invokes hsch sending it a command to execute. The shell does any file name expansion before hsch executes. Hcsh spawns a prefetching process, passing it the arguments to the command. This process assumes that all arguments without a leading ‘-’ are names of files that the command will read and starts to prefetch them serially and sequentially into the buffer cache. Meanwhile, the parent hcsh process invokes the command whose reads hopefully hit the prefetched data in the buffer cache. The command and the prefetch process then run concurrently.Figure 1b shows the flow of events for make experiments. The make program was modified slightly so that the first thing it does is fork off a prefetching process. The parent process then simply con-tinues on, executing the standard make code. The files to prefetch were determined in advance using a file system tracing facility [Mummert92] and hard-wired into the prefetcher. Thus, the prefetching was based on accurate knowledge of the accesses to be performed.The prefetch mechanism differs in the local and remote cases. In the local case, the prefetch pro-cess sequentially reads files in 64K chunks using standard system calls. This had the effect of loading them into the buffer cache where they were available to the application. For files on the Coda server, the prefetch8910allowed the prefetch process to flood the I/O subsystem with prefetch requests. This led to its own unique problem, thread starvation. Because Coda used a fixed number of worker threads to handle user requests, the prefetch process monopolized these threads and starved the user’s demand reads. Clearly, prefetches must operate at lower priority than demand fetches. We fixed the problem in Coda by limiting the number of threads that could be devoted to prefetching before making the measurements in Table 4.We anticipate a similar problem at the local disk once we fill disk queues with prefetch requests. A large, efficient, prefetch request could stall a demand request behind it. New functionality in disk control-lers that could suspend a low priority request to service a demand request immediately could help resolve this problem. A less attractive alternative is to keep prefetch requests small so that they never take long to complete.The voracious Coda prefetcher created another problem. Sometimes it got so far ahead of the user process that it flushed unused prefetched data out of the cache. This can have dramatic consequences. One job initially experienced a 17% slowdown with prefetching because it had to go to disk to retrieve data that the prefetcher had flushed out of the cache. The local disk prefetcher occasionally had the same problem. For these preliminary tests, we avoided this problem by using a buffer cache big enough to hold all of the data. The long-term solution is to track user reads of prefetched data and throttle prefetching accordingly.Actually, this cache overrun problem had an additional, ironic twist. The cache held on to already used and no longer needed data even as it was ejecting prefetched data that had yet to be used. The used data had been more recently accessed and so was higher in the LRU list. This phenomena highlights the importance of combining prefetching with buffer management.5 Work in Progress and Future WorkThe experimental results support our contention that TIP offers a powerful mechanism for over-coming the looming I/O crisis. They also demonstrate the need to integrate TIP with low-level resource management. To this end we are implementing TIP in our Mach/Unix research environment and instru-menting important applications, including the ones already tested, to provide hints. Since we feel that the greatest gains of TIP occur with high levels of concurrency in the I/O subsystem, we are also building a disk array on which our implementation of TIP can flex its muscles. In the rest of this section, we describe a few possibilities for future work on even more powerful TIP mechanisms.Although we feel that often programers can easily give good hints, automatic hint generation would be even easier and would provide a much broader base of applications providing hints. Given a hint interface, why not extend optimizing compiler techniques to use it? While file names and access patterns could be concealed in complex data structures, we believe that many programs access files simply; file names come as arguments, access calls are made from outer loops, and offsets are computed simply from previous offsets or loop indices. With such straightforward programming styles, we expect that precise hints can be extracted automatically.In some cases, even programmers may not fully understand the file accesses their programs make. An access pattern profiler could be built on top of an efficient file system tracing facility [Mummert92]. The profiler could help programmers improve the quality of their hints, or it could be used directly to gen-erate hints for future runs.A variation on giving hints for other programs is giving hints for library routines such as a fast-fourier transform (FFT) procedure in a math library. Since the programmer may not be familiar with the implementation of FFT, they may be unable to give good hints. The math library could export the routine11fft.hint to facilitate hints. A user program could call fft.hint and let it give the appropriate hint to the file system. Effectively, the application gives a hint to the library which repackages it and sends it to the file system. This is an example of how hints can be used to pass information through multiple layers of soft-ware.6 Related WorkThe idea of giving hints is not new. For example, Trivedi suggested using programmer or compiler generated hints for prepaging [Trivedi79]. Hints are now widely enough understood that they appear in various existing implementations. For example, Sun Microsystems’ operating system provides two “advise” system calls that instruct the virtual memory system’s policy decisions [SunOS-vadvise].Database systems researchers have long recognized the opportunity to accurately prefetch based on application level knowledge [Stonebraker81]. They have also extensively examined the opportunity to apply this knowledge through advice to buffer management algorithms [Sacco82, Chou85, Cornell89,Ng91] and for I/O optimizations [Selinger79]. We hope to extend these techniques to prefetching. Also, our work emphasizes a more solid partitioning of function between application and operating system.Many researchers have looked into prefetching based on access patterns inferred from the stream of user I/O requests [Kotz91, Tait91, Palmer91, Korner90]. Our view of the problem is perhaps most simi-lar to Korner’s who recognized the value of high-level hints as a means of bridging levels of abstraction from files to disk blocks. Her characterizations of access patterns, like ours, are at a high level of abstrac-tion. But, we carry this approach further and ask for hints from applications themselves to bridge the gap between applications and the operating system.Recently, researchers have proposed an object-oriented file system layered on top of the Unix file system called ELFS [Grimshaw91]. ELFS has knowledge of file structure and high-level file operations that allow it to help prefetch and caching operations. However, ELFS emphasizes user control over file activity. It would be possible instead for users to give hints to ELFS which would translate them into hints for the low-level file system. Thus, hints could be used to bridge layers of the system at the application level. In such a context, ELFS and TIP would complement each other well.Our work differs from all previous prefetching work in one important respect. We do not view the overlapping of I/O with computation as the major benefit of prefetching. The success of such overlapping is extremely sensitive to the ratio of time spent on I/O relative to computation and that ratio changes con-stantly as processor performance increases. Instead, we believe that the greatest benefit of prefetching will come from the exposure of I/O concurrency that can take advantage of new high-throughput technologies. Thus, we believe that the high I/O concurrency provided by early, accurate user-supplied hints is critical to the ultimate success of prefetching.7 ConclusionTransparent Informed Prefetching, TIP, extends the power of caching and prefetching to reduce file read latency by exploiting application-level knowledge of future access patterns. These access patterns are expressed to TIP in the form of hints that disclose rather than advise and serve to expose concurrency in the I/O workload. TIP systems can then cooperate with resource management policies to increase the utilization and efficiency of high-throughput network and storage systems. This effectively converts the high throughput of new peripheral technologies into low read latency for application programs.12In this paper, we have introduced informed prefetching as the key to reducing read latencies for application programs whose files do not cache well because of their large size, non-sequential access pat-terns, or inherently read-once nature. The key to informed prefetching is knowledge of future application file references conveyed by hints expressed in terms of operations on files, not resource management pol-icy options. However, TIP should not operate independent of resource management because it can squan-der resources if not properly checked.To demonstrate our ideas and develop experience instrumenting programs with hints and incorpo-rating prefetching into caching access patterns, we have conducted a few preliminary experiments. The results of these experiments are quite promising. Applications obtaining data from a remote file server may be able to reduce their execution time by up to 30% and applications obtaining data from a single local disk may see 13% reductions in their execution time.8 AcknowledgmentWe would like to thank Lily Mummert for her important contributions to this paper. In addition to many helpful discussions, she constructed the original file tracing facility, later adapted it to our special needs, and modified the Coda File System to support low-priority prefetch requests.We also thank Mark Holland for his constructive comments about an early draft of this paper.9 References[Amdahl67]Amdahl, G.M., “Validity of the single processor approach to achieving large scale computing capabilities,”Proc. 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