Department of Biological Sciences,
Bisection algorithm is used to find a solution to the above function g(a) on the interval [0.84, 0.85], where g(0.84) and g(0.85) have opposite signs. The final approximation function is: F(x) = 0.6833* e –0.8412(x-0.387)
transformed cells. It is possible that the structure is affected by binding with actin in the association of adhension sites [4]. The objective of this paper is to analyze the pattern in which PKC mediates dissolution of SFs by a mathematical model.
Nonlinear Modeling on Protein Kinase C(PKC)-Epsilon Inverse Regulation of Stress Fibers in Oncogenically Transformed Cells
Yingxin Li1,2, Carol A. Heckman1, Julie A. Barnes2 1 2 Department of Biological Sciences, Department of Computer Science, Bowling Green State University, OH 43403 Bowling Green State University, OH 43403 Email: {liyingx|heckman}@ jbarnes@cs.bgnet.bgsu
a( x x )
Min
a
¦(y
i 1
n
i
f 0 e a ( xi x0 ) ) 2
So, we need to find the first derivative of the above equal to 0. g(a)=
¦(y
i 1
n
i
f 0 e a ( xi x0 ) ) e a ( xi x0 ) ( xi x0 ) =0
Fig.2. Characteristic appearance of 1000W cells after siRNA transfection. A) The appearance of cell exposed to random sequence siRNA is similar to that of unexposed cells at the peak of SF formation. In cells exposed to specific siRNA against PKC-İ (see B-D), PMA induces extensive SF formation, and often causes formation of parallel arrays. B) Treatment with PMA for 2 h, C) Treatment with PMA for 5 h, D) Treatment with PMA for 10 h. Magnifications: x1,100.
2. Methods
2.1. Mathematical modeling
The PKC-H content in cells with PMA treatment and SF counts were published elsewhere [3]. Based on the assumption that the rate of PKC-H decay is proportional to the PKC-H level in the cell, we assumed a half-life of 24 hours in order to calculate PKC-H contents in 1000W cells treated with anti-PKCH oligodeoxynucleotide (antisense) reagent. Matlab5.2 (MATLAB The language of technical computing, Math Works Inc., 1998) and Fathom1.1 (Dynamic statistics software, KLP Technologies, 2001) software were used to do the linear approximation. In nonlinear approximation, two C++ programs were developed by Li (unpublished data) to find the solution by the application of bisection algorithm.
1. Introduction
PKC is a family of serine, threonine kinases consisting of isozymes, DEIEIIJGHK, P T, Oand ]With the exceptions of O(L)and ]PKCs conduct signaling downstream of both tyrosine kinase receptors and G-protein coupled receptors. Recent evidence [1] showed that PKCHwas overexpressed in androgen-independent lines of prostatic epithelial cells. Other evidence [2] showed PKCH was linked to integrin ȕ1 through interaction with RACK, and associated with F-actin via its actin-binding motif, thereby mediating increased adhesion and mobility. The evidence from the Heckman's group indicated PKC-H can decrease the SF formation in oncogenically
Proceedings of the 2004 IEEE Computational Systems Bioinformatics Conference (CSB 2004) 0-7695-2194-0/04 $20.00 © 2004 IEEE
3. Results
The original data of PKC-H and SF-forming cells seems to follow the curve of the following function:
i 0 F(x) = F0* e , where F is the percentage of SF-forming cells and x is the content of PKC-H. By using the linear approximation software from Matlab and Fathom, we got two functions respectively: F(x) = 0.3806* e –0.3051(x-0.387) and F(x) = 0.6833* e –0.727(x-0.387). Nonlinear approximation: Applying least-square method, we want to get
Abristate 13-acetate (PMA), a tumor promoter, provides effective means of reversibly converting tissue culture cells to a state which resembles that of transformed cells. PKC isozymes can be activated by PMA and cause reorganization of actin-containing structures. The purpose of the current research is to analyze the pattern in which PKC mediates dissolution of stress fibers (SFs) by a mathematical model. Several mathematical models were tried, including linear and nonlinear approximations, in order to establish the relationship between PKC-İ and SF accumulation in 1000W cells. Applying a non-linear approximation and using a bisection algorithm, an exponential function was derived to show how PKC-İ inversely controlled SFs. We use RNA interference (RNAi) technology to knock down the PKC-İ expression in order to validate this mathematical model. In the time course of SF formation following PMA exposure, a special feature of parallel arrays showed in cells with PKC-İ siRNA transfection.
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saudi journal of biological sciences投稿说明
saudi journal of biological sciences投稿说明
《沙特生物科学杂志》（Saudi Journal of Biological Sciences）
是一本开放获取的同行评审科学期刊，由沙特阿拉伯大学主办。
该杂志致力于发表原创的基础和应用生物学研究，涵盖了从生物化学和分子生物学到生态学和环境科学的各个方面。
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蛋白质相关实验技术操作指南
1、Western blotting:Western blotting using ECL reagentused by：Laboratory of P.J. Hansen,Dept. of Animal Sciences, University of FloridaKamps's Western Blotting Protocolused by：Sefton Lab, Salk InstituteDry Transfer 干法蛋白转膜used by：The Preuss Lab,The Division of Biological Sciences,The University of ChicagoWestern Blot of TBP from TBP-GST bacteriaused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFWestern Blot/Anti-P-CREBused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFWestern blotting protocol for 1C2, 3B5H10, and 4C8 Antibodiesused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFProtocol for anti-HA antibody Western Blottingused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFProbing and Stripping of Western Blotused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Western Blotting Protocolused by：Mirmira Laboratory at the University of VirginiaWestern Blotting and Immunostainingused by：Chazin Lab, Center for Structural Biology, Vanderbilt UniversityWestern Blotsused by：Lab of Dr. Mark Barton Frank, Oklahoma Medical Research FoundationWestern Blotting - Antibodiesused by：The Minion Lab, College of Veterinary Medicine at Iowa State UniversityWestern Blottingused by：Cepko/Tabin Lab, Harvard UniversityCarbonate Solution For Western Blotused by：Dr. DE Koshland, Carnegie Institution of WashingtonWestern Blot with BSAused by：Dr. DE Koshland, Carnegie Institution of WashingtonMETHOD for Western Blotsused by：Dr. DE Koshland, Carnegie Institution of WashingtonWestern Blotsused by：Michael Koelle's Lab,Department of Molecular Biophysics and BiochemistryYale University2、蛋白分离/提取/浓缩Lysis Buffersused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFYeast Protein Isolation "Yaffe-Schatz"used by：Amberg Lab ,Upstate Medical UniversityGuanidine Hydrochloride Purification of Proteins From SDS PAGEused by：Gottschling Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Yeast protein prep for SDS PAGE and western (rapid)used by：Gottschling Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Yeast protein prep for SDS PAGE and western (glass bead)used by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Purification of TFIIIC from yeastused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Purification of TFIIA from E. coliused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical InstituteTCA protein precipitationused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Purification of MLCK ( Myosin Light Chain Kinase )from Rabbit Skeletal Muscle肌球蛋白轻链激酶used by：Stull Lab,University of Texas, Southwestern Medical CenterPurification of Calmodulin from Bovine Brainused by：Stull Lab,University of Texas, Southwestern Medical CenterMyosin Light Chain Preparation from Skeletal and Cardiac Muscleused by：Stull Lab,University of Texas, Southwestern Medical CenterPurifying Protein from Inclusion Bodiesused by：Chazin Lab, Center for Structural Biology, Vanderbilt UniversityProtocol for Protein Extraction from Plantused by：The University of Nebraska-Lincoln Protein Core Facility (PCF)Taq Polymerase Purificationused by：Cepko/Tabin Lab, Harvard UniversityYeast Protein Prep (No Boil)used by：Dr. DE Koshland, Carnegie Institution of WashingtonYeast Protein Prep (Boil)used by：Dr. DE Koshland, Carnegie Institution of WashingtonGST Fusion Protein Prepused by：Vesicle Trafficking, Stanford University3、蛋白质检测分析：AMIDO BLACK STAINused by：Hancock Laboratory Methods,Department of Microbiology and Immunology,University of British Columbia, British Columbia, CanadaJames Hardwick's angiotensin assay protocolused by：Sefton Lab,Salk InstitutePhosphoamino acid analysis:Mark Kamps's methodused by：Sefton Lab,Salk InstituteULTIMATE HIS-UB ASSAY FORused by：the Tansey Lab at Cold Spring Harbor LaboratoryULTIMATE HIS-UB ASSAY FOR YEASTused by：the Tansey Lab at Cold Spring Harbor LaboratoryProtocol for Beta-Hexosaminidase RBL-2H3 Secretion Assayused by：meyer lab,Stanford UniversityMeasurement of Myosin Regulatory Light Chain (RLC) Phosphorylationused by：Stull Lab,University of Texas, Southwestern Medical CenterBicinchoninic Acid (BCA) Protein Assayused by：David R. Caprette, Rice UniversityBiuret Protein Assayused by：David R. Caprette, Rice UniversityBradford protein assayused by：David R. Caprette, Rice UniversityHartree-Lowry and Modified Lowry Protein Assaysused by：David R. Caprette, Rice UniversityColorimetric Assaysused by：David R. Caprette, Rice UniversityKd measurement, fitting, calculation, and simulationused by：Chazin Lab, Center for Structural Biology, Vanderbilt University4、蛋白标记修饰DSP Crosslinkingused by：Peter Novick Lab, Department of Cell Biology Yale University School of Medicine Labeling Gc-Globulin with Carboxyfluorescein Succinimidyl Esterused by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS)Labeling Tubulin with Tetramethylrhodamine Succinimidyl Esterused by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS)Labeling Gizzard Vinculin with Tetramethylrhodamine Iodoacetamideused by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS)Labeling Gizzard Alpha-actinin with Tetramethylrhodamine Iodoacetamideused by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS)Labeling Gizzard Myosin with Tetramethylrhodamine Iodoacetamide (primarily 17kD MLC) used by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS)Labeling Gizzard Myosin with Tetramethyorhodamine Iodoacetamide (MHC and 17kD MLC)used by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS) Labeling Muscle Actin with N-(1-pyrene) Iodoacetamideused by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS) Labeling Muscle Actin with Tetramethylrhodamine Iodoacetamideused by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS) Labeling Muscle Actin with Carboxyfluorescein Succinimidyle Esterused by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS) Labeling Muscle Actin with 5-Iodoacetamidofluoresceinused by：Yu-Li Wang Lab,University of massachusetts Medical School(UMASS) ultimate mammalian cell pulse-chaseused by：the Tansey Lab at Cold Spring Harbor Laboratoryultimate yeast pulse-chaseused by：the Tansey Lab at Cold Spring Harbor LaboratoryGluteraldehyde Conjugation of Oligopeptides to Proteinsused by：Lab of Dr. Mark Barton Frank, Oklahoma Medical Research Foundation Fluorescein labeling of proteinsused by：David Chambers,Salk instituteBiosynthetic labelingused by：Sefton Lab, Salk Institute , San Diego, California5、免疫沉淀(IP/CoIP/ChIP)Immunoprecipitation buffers and protocolsused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFCell Lysis/Western/IPused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSF Amplification and Labelling with Cy dyesused by：Yale Genome Analysis Center, Yale UniversityChromatin Immunoprecipitation from Mammalian Cell Extractsused by：Yale Genome Analysis Center, Yale UniversityChromatin Immunoprecipitation from Yeast Whole Cell Extractsused by：Yale Genome Analysis Center, Yale UniversityImmunoprecipitationused by：Hancock Laboratory Methods. Department of Microbiology and Immunology, University of British Columbia, British Columbia, CanadaUltimate yeast denaturing IPused by：the Tansey Lab at Cold Spring Harbor LaboratoryULTIMATE FREEZE-THAW LYSIS FORused by：the Tansey Lab at Cold Spring Harbor LaboratoryUltimate mammalian nondenaturing IPused by：the Tansey Lab at Cold Spring Harbor LaboratoryUltimate mammalian denaturing IPused by：the Tansey Lab at Cold Spring Harbor LaboratoryUltimate yeast ChIP assayused by：the Tansey Lab at Cold Spring Harbor Laborat oryChromatin Immunoprecipitation Assay and PCRused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Yeast Chromatin Immunoprecipitation (ChIP)used by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Mirmira Lab ChIP Protocolused by：Mirmira Laboratory at the University of VirginiaChIP Assay Protocolused by：Mirmira Laboratory at the University of VirginiaImmunoprecipitation and Immune Complex kinase assayused by：Sefton Lab, Salk InstituteGeneral Principles of Immunoprecipitationused by：Sefton Lab, Salk Institute6、融合蛋白表达及纯化Use of B-PER lysis reagent to purify recombinant proteins tagged with His6 or maltose binding protein used by：Smith Lab,Division of Biological Sciences,University of MissouriBacterial Expression of Kinesin Motorsused by：Liz Greene and Steve HenikoffPurification of recombinant sBRF M166Lused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Protein Expression and Purification of RPA70-ABused by：Chazin Lab, Center for Structural Biology, Vanderbilt UniversityCo-Expression and purification of human DNA primase p49-p58 subunits引发酶p49-p58亚基共表达纯化方法used by：Chazin Lab, Center for Structural Biology, Vanderbilt UniversityProtein Expression and Purification of MBP-T antigen MBP-T抗原表达纯化used by：Chazin Lab, Center for Structural Biology, Vanderbilt UniversityPerspectives on Baculovirus Expression Systems表达used by：Lab of Dr. Mark Barton Frank, Oklahoma Medical Research FoundationExpression & Purification of His Tagged Proteins in E. coliused by：Cepko/Tabin Lab, Harvard University7、相互作用分析Amplifying a large phage-display library without losing diversityused by：Smith Lab,Division of Biological Sciences,University of MissouriProtein Interaction Analysis Using an IASYS Biosensorused by：Kitto Lab, The University of Texas at AustinYeast Two-Hybrid Screen with Library and Baitused by：Mirmira Laboratory at the University of Virginia8、蛋白电泳/双向电泳SDS-PAGEused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFGel Drying干胶used by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFNuPAGE Gel Electrophoresis 蛋白电泳used by：Kitto Lab, The University of Texas at AustinIsoelectric Focussing of Membrane Proteins by Slab Gel Methodused by：Hancock Laboratory Methods,Department of Microbiology and Immunology,University of British Columbia, British Columbia, CanadaSilver Staining SDS PAGE Gelsused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute E. coli total protein for SDS PAGEused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Comassie Blue Protein gel stainused by：Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute Coomassie & Silver Staining of Polyacrylamide Gelsused by：Lab of Dr. Mark Barton Frank, Oklahoma Medical Research Foundation2-D Polyacrylamide Gel Electrophoresisused by：Molecular Profiling Initiative, National Cancer Institute(NCI)Silver Staining of SDS-PAGE Gelsused by：The Minion Lab, College of Veterinary Medicine at Iowa State UniversitySDS-PAGE Gelsused by：The Minion Lab, College of Veterinary Medicine at Iowa State UniversityCuCl2 Staining of SDS-PAGE Gelsused by：Cepko/Tabin Lab, Harvard UniversityElectroelution of Proteins From SDS-PAGE Gelsused by：Drs. C Cepko and C Tabin, Harvard UniversitySilver Stain of Protein Gelsused by：Dr. DE Koshland, Carnegie Institution of WashingtonSDS-PAGE （BIO-RADused by：Dr. DE Koshland, Carnegie Institution of WashingtonSDS-PAGEused by：Michael Koelle's Lab,Department of Molecular Biophysics and Biochemistry Yale University9、质谱分析Polycrystalline thin films质谱样品准备used by：Prowl Lab,Rockefeller UniversitySeeded films (Vorm-Roepstorff)used by：Prowl Lab,Rockefeller UniversityDried dropletused by：Prowl Lab,Rockefeller UniversityIn-gel Tryptic Digest for Protein ID by Mass Spectrometryused by：Mitshison Lab, Department of Systems Biology, Harvard Medical School10、crystallizationPolycrystalline thin filmsused by：PROWL, Rockefeller UniversitySlow crystallizationused by：PROWL, Rockefeller UniversityCrystallization of Kinesin Family Motor Proteins驱动蛋白家族的结晶条件和晶体参数used by：Liz Greene and Steve HenikoffCrystallization Trialsused by：Liz Greene and Steve Henikoff11、in vitro protein synthesisProtein Syntheses in Cell Free Systemsused by：The Laboratory of William Heidcamp at Gustavus Adolphus University12、蛋白纯化/层析6xHis-tagged protein purification using Qiagen Ni-NTA Column under Native Conditionsused by：Sugden lab,McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School Purification of dnEBNA-1/Soft from E. coli BL21 LysSused by：Sugden lab,McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School Purification of GST fusion proteins in E.coli GST融合蛋白纯化（方法四）筛选表达株used by：Sugden lab,McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School Purification of GST fusion proteins in E.coli GST融合蛋白纯化，方法三，纯化小量蛋白used by：Sugden lab,McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School Purification of GST fusion proteins in E.coli GST融合蛋白纯化，方法二used by：Sugden lab,McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School Purification of GST fusion proteins in E.coli GST融合蛋白纯化，方法一used by：Sugden lab,McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School Purification of 6xHis epitope tagged proteins by Ni-NTA-Agarose His标签蛋白纯化used by：Sugden lab,McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School Fusion Protein Isolation 融合蛋白分离纯化used by：Peter Novick Lab, Department of Cell Biology Yale University School of MedicineAffinity Column Preparation 亲和层析柱制备used by：Peter Novick Lab, Department of Cell Biology Yale University School of MedicinePreparation of Affinity Column制备亲和层析柱used by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSFColumn Buffersused by：Steven Finkbeiner, Departments of Neurology and Physiology, UCSF13、蛋白定量Glutathione - a microassay for determining glutathione content in cells 检测细胞谷胱苷肽含量used by：Laboratory of P.J. Hansen,Dept. of Animal Sciences, University of FloridaBradford Protein Assay - a microassay for determining protein content in a 96-well microtiter plate format used by：Laboratory of P.J. Hansen,Dept. of Animal Sciences, University of FloridaLowry Protein Assayused by：Laboratory of P.J. Hansen,Dept. of Animal Sciences, University of FloridaBradford Assayused by：Kitto Lab, The University of Texas at Austin欢迎您的下载，资料仅供参考！致力为企业和个人提供合同协议，策划案计划书，学习资料等等打造全网一站式需求精品文档。
protein purification and characterization
Protein production may be from:- Extra cellular - Intra cellular Protein production by Recombinant DNA technology:- Homologous - Heterologous. * Plants * Animals (tissues)
Protein Purification and Characaman
Contact Information
Department of Biological Sciences S3 Level 04-08 Tel: 6874 1163 Fax: 6779 5671 E-mail: dbsjayar@.sg
Preliminary Purification/Conc.
Commonly used methods are :
Dialysis using cellulose tubing Concentration by precipitation (salt, solvent etc.), Gel filtration, Ion-exchange chromatography etc.. Ultra-filtration through membrane system e.g. Centriprep MWCO 3000 / 10000 Lyophilization
Organic Precipitation
Ordered water molecule structure around hydrophobic areas displaced by organic solvent molecules (higher solubility of these molecules) Aggregation and precipitation occur due to electrostatic and dipolar van der waals forces Similarly for organic polymers (like PEG)
生物专业英语作文
生物专业英语作文The field of biological sciences encompasses a vast and diverse array of disciplines, each exploring the intricate workings of living organisms and the natural world. From the microscopic processes within cells to the complex ecosystems that sustain life on our planet, the study of biology offers a profound understanding of the fundamental principles that govern the living world.One of the core branches of biological sciences is cell biology, which delves into the structure and function of the basic building blocks of life – the cell. Researchers in this field investigate the intricate machinery that powers cellular processes, such as metabolism, cell division, and signal transduction. By unraveling the mechanisms that govern cellular behavior, cell biologists pave the way for advancements in fields like medicine, biotechnology, and developmental biology.Another crucial aspect of biological sciences is molecular biology, which examines the molecular-level interactions that underpin the flow of genetic information and the expression of genes. Molecularbiologists study the structure and function of DNA, RNA, and proteins, shedding light on the fundamental principles of heredity, genetic variation, and the regulation of gene expression. This knowledge has far-reaching implications, from understanding the molecular basis of diseases to developing novel therapeutic strategies.Evolutionary biology is a captivating branch of the biological sciences that delves into the origins, diversification, and adaptation of living organisms over time. By analyzing the patterns of genetic and morphological changes, evolutionary biologists reconstruct the evolutionary history of species and elucidate the mechanisms driving the emergence of new traits and the emergence of new species. This field not only enhances our understanding of the natural world but also provides crucial insights into the origins of human life and the evolutionary processes that have shaped our own species.Ecology, another pivotal discipline within the biological sciences, examines the intricate relationships between living organisms and their environment. Ecologists study the flow of energy and the cycling of nutrients within ecosystems, as well as the complex interactions that occur between different species. This knowledge is essential for understanding the delicate balance of natural systems and developing strategies for sustainable resource management and environmental conservation.Neuroscience, a rapidly advancing field within the biological sciences, focuses on the structure and function of the nervous system, including the brain, spinal cord, and peripheral nerves. Neuroscientists explore the neural mechanisms underlying cognitive processes, sensory perception, motor control, and behavior, with the ultimate goal of unraveling the mysteries of the human mind and developing treatments for neurological disorders.In addition to these core disciplines, the biological sciences encompass a wide range of specialized fields, such as microbiology, which investigates the diverse world of microorganisms; immunology, which examines the intricate workings of the immune system; and developmental biology, which explores the processes by which multicellular organisms grow and differentiate from a single cell into complex, functional entities.The significance of the biological sciences cannot be overstated. The knowledge gained through research in these fields has transformed our understanding of the natural world and has led to countless advancements in fields such as medicine, agriculture, and environmental conservation. From the development of life-saving drugs to the implementation of sustainable farming practices, the contributions of biological scientists have had a profound impact on the well-being of humanity and the health of our planet.As we continue to explore the wonders of the living world, the biological sciences will undoubtedly play an increasingly crucial role in addressing the pressing challenges facing our global community. Whether it's finding solutions to emerging infectious diseases, developing renewable energy sources, or unraveling the complexities of the human brain, the insights and innovations generated by the biological sciences will be essential in shaping a better future for all.。
美国留学生物工程专业个人陈述范文
美国留学⽣物⼯程专业个⼈陈述范⽂ 申请美国留学的学⽣不少，那么美国留学⽣物⼯程专业的个⼈陈述范⽂是如何呢?这个很多留学⽣⽐较感兴趣的话题。
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美国留学⽣物⼯程专业个⼈陈述范⽂三篇 范⽂⼀ With the approach of new century, the developing China is requiring better trained and more highly educated men and women than ever before in history. In order to make more contributions to the society and, at the same time, satisfy my keen interest in science, I am looking forward to beginning my graduate study. I heard of Case Western Reserve University as early as when I was an undergraduate student. She is one of the most highly regarded universities in the world and is an ideal place for ambitious youth. I plan to study for Ph.D. in Biochemistry at Case Western Reserve University with special interests in metabolism, macromolecular synthesis, and protein crystal growth. I have had plentiful preparations. First, when being an undergraduate in the Department of Chemical Engineering at Tsinghua University, I got very extensive and intensive education. I took many courses on chemistry and the related subjects, and earned high scores for most of them. Second, my major, Polymer, can be put into good use in Biochemistry programs because Polymer is closely related with biological Macromolecule. Third, I have working experience that enriches my theory and laboratory skills. From 1990 to now, I have been engaged as an Assistant Engineer by the Research institute, Beijing Yanshan Petrochemical Corporation (RIBYPC). In the first year, I was in charge of a 5-litre reactor for polymerization of Carboxylated Butadiene-Styene Latex. Then I was transferred to another research group to synthesize PET/PHB copolymer, a kin of polyester, which has the property of Liquid Crystal. I am the assistant head of the group. We can prepare the novel polymer with high molecule weight and excellent property in a 2-litre stainless steel reactor. During this monomers, with purity of more than 99.99%; this made my leader very satisfied. More than four years of working experiences expand my capacity. I often make use of NMR, X-ray, DSC and other instrumental methods for research. Among them, I am most skilled in NMR reactors, I have experiences on solving problems of Engineering and Mechanics. What is more, I am familiar with computer operation and some application software. The above information about my specialty may be helpful for you to evaluate me. It is said that the 21st century will be the age of Life Science. I hope to enter the esteemed Case Western Reserve University to face this challenge. I am confident tat I shall be an excellent fellow. After completing my graduate study, I would like to return to my homeland and make use of my knowledge to serve the people. By the way, I would like to give thanks to my parents. Being their oldest son, I am offered the most formal education and the deepest love. I never forget the 18-year’s life with them. Twelve years in the countryside and six years in Shengli Oil Field bestowed me the character of diligence, resolution, and perseverance, as well as the deep love of nature and life. I am also indebted to my dear wife. Without her never-ended encouragement and support in these years, I could not become closer and closer to the gate of the eminent Case Western Reserve University. 范⽂⼆ Knowing where is heading during navigation brings assured happiness. As a student majoring in Biochemistry, I began my odyssey five years ago, when our class had a new biology teacher, who was young and energetic. He taught us in an entertaining way and communicated with us quite well. I liked him very much and was impressed by the knowledge of Biological Sciences. He opened new doors to the realm of Biology in my life. And with time being, I feel more and more sure about my destination. Although the trail of navigation has not always been definitely straight, I believe it leads me to my dream. Because of my excellent performance in the National Olympic Mathematics Contest of High School Students in 1994 and my outstanding academic record in senior high school, I had the opportunity to be admitted to Peking University or Tsinghua University, two most selective universities in China, waived of the Admission Examination. But if I took the chance, I couldn’t select biological sciences as my major. So I gave up the precious chance and took the Admission Examination. I succeeded and was admitted by the Department of Biochemistry and Molecular Biology in Peking University, which ranks first in biological science education and research in China and has raised many scholars including members of Chinese Academy of Sciences. In the first three years in university, my curriculum has a broad range, covering both natural and humanity sciences, as well as putting emphasis not only on biological sciences but also on closely related courses. I have dedicated my energy to my study and have received a complete, profound and strict training in biological sciences with the combined strength of individual and professors' help. Playing basketball is also a solid part of my campus life. I am an activemember in the basketball team of the College of Life Sciences in Peking University. As a point guard, the organizer of the team's attack, I have learned to make the five players to be a strong group in a game. Last year, we ranked the third in Peking University Cup among the thirty-six teams. This experience endows me a strong sense of responsibility, confidence and team-working spirit. To be a successful scientific researcher requires not only academic potential but also independent research ability. A student will develop capability for independent research by working closely with a scholar. For this reason, I entered the National Laboratory of Protein Engineering and Plant Genetic Engineering and participated the Group of Protein Structure and Function. Now I cooperate with two graduate students, one of whom will go to the Harvard Medical School to continue his research work. Our ultimate goal is to develop a new thrombolysis drug, which is supported by the National 863 Hi-Tech Planning. (Please check Research Experience for detail.) By the three months here, I have been able to do many experiments independently and have obtained serious attitude and cooperation in scientific work. I have a sublime dream to be one equipped with exceptional experiment skills in addition to advanced scientific and technological knowledge. In my mind Pennsylvania State University is an ideal place to purse the graduate study, which is intellectually exhilarating and challenging. I respect your rigorous scientific approach, original idea and outstanding achievements. I am eager to join a group in which I can make the best use of my capabilities and combine my personal intelligence with group cooperation to full-fill the group’s benefit as well as to make my dream come true. The Department of Pharmacology is definitely this type. With the fast development in the field of life sciences, human is getting more and more interested in probing into the nature of life itself and every great achievement in the study of life is sure to put light to our understanding of ourselves and to benefit our people and society as a whole. The field of Pharmacology has particular importance to serve man’s purpose above. A scientist of Pharmacology is not only a researcher, but also the creator of the future world. I think the challenging Pharmacology is the most suitable field for me to begin my graduate study, which is more than a continuation of undergraduate study and is of not only a matter of greater knowledge. The aim of it is to prepare students to enter a profession in which the knowledge is put into daily use. I am interested in the field of signal pathway in tumor formation. Several professors' research impressed me, including Dr. Mulder and some other professors. After obtaining my Ph.D., I plan to do research work in an institution either domestically or overseas. I believe that such a position provides the largest room in which I can make the most enthusiastic dedication to the world of sciences. I believe the advanced courses, distinguished faculty and the best-equipped laboratories of your group will help me make the desired achievements. With the conviction that I can sustain me through the intense graduate study, I have made the decision to apply for Pennsylvania State University and hope your serious consideration.。
香江学者计划
3) Most Cited Paper Award (2005-2008) by “Bioorganic & Medicinal Chemistry”
Major Research Interests:
1) Natural Products Chemistry;2) Bioorganic Chemistry; 3) Metabolomics
Academic Discipline:(Please tick one)
Basic Research (基礎研究)Pleasespecify your discipline (e.g. Physics, Maths)________________________
Information Technology (信息技術)
Name: (English)JIANG, Zhi-Hong
(Chinese)姜志宏
Academic Rank:Professor
Administrative Post (if any):
Associate Director
Department:School of Chinese Medicine
Institution:Hong Kong Baptist University
Are you a member of the Society of Hong Kong Scholars?
Good morning everyone
Good morning everyone .I’m 文星，易，a freshman from Department of Biological Sciences .It’s my honor to stand here to give a speech .My topic is”Our dreams and the dream of china”.Our president Xi came up with the dream of the Chinese nation’s rejuvenation on December 29,2012.How can we understand the dream that emerges in it?First ,we must know China is an ancient country with more than five thousand years of history .Our country exists in the world for such a long time that she not only possesses many great splendors,but also goes through many hardships.When we put our eyes on Chinese modern history ,almost every Chinese will feel sad and humiliated .Although now we live well ,we can’t make up for past humiliation.In other word,We have solved the problem of food and clothing ,and we need tofind the lack of culture ,to develop the technology of our own ,to retrieve the spirits which were forgotten,to learn the real wonderful thing .....Just do as our ancestors in many years ago .Then ,we create,and architect our nation’s soul.This is the dream of the Chinese nation’s rejuvenation.The word “Dream” always be connected to something poetic andinspiring.Around my life ,many people dream to get achievement in academy,some want to be successful in business , and some are busy with meeting morepeople ......I have ever wanted to be a pilot ,a painter,a writer ......something like these .Now I also has my dream,and I never stop dreaming .Life will become brighter because of dream ,and you will become passionate because of dream.When people be involved in accomplishing their dream,the all kinds of dream will converge ,impact each other ,and burst out wonderful thing.Those dreams eventually consist of the dream of the Chinese nation’s rejuvenation .That’s all .Thanks!。
国家自然科学基金申请代码（App...
国家自然科学基金申请代码（Application code for National Natural Science Foundation of China）A. Department of Mathematical SciencesA01MathematicsA0101number theoryA010101Analytic theory of numbersA010102Algebraic number theoryA010103Number theory applicationA0102AlgebraA010201Group and its representationA010202Li Qun and Lie algebraA010203Algebraic groups and quantum groups A010204Homology and K theoryA010205Ring and algebraA010206Coding and CryptographyA010207Algebraic geometryA0103geometryA010301Global differential geometryA010302Complex geometry and algebraic geometryA010303Geometric analysisA0104topologyA010401Algebraic topology and differential topology A010402Topology on low dimensional manifoldsA010403General topologyA0105Function theoryA010501Function theory of many complex variablesA010502Complex dynamical systemA010503Theory of functions of simple complex variable A010504Harmonic analysis and wavelet analysisA010505Function approximation theoryA0106functional analysisA010601Nonlinear functional analysisA010602Operator theory and operator algebraA010603Space theoryA0107Ordinary differential equations and dynamical systems A010701Functional differential equationsA010702Qualitative theory and stability theoryA010703Bifurcation theory and chaosA010704Differential dynamical systems and Hamiltonian Systems A010705Topological dynamical systems and ergodic theoryA0108partial differential equationA010801Partial differential equations in geometry, physics, and mechanicsA010802Nonlinear elliptic and Nonlinear Parabolic EquationsA010803Mixed and degenerate partial differential equationsA010804Nonlinear evolution equations and infinite dimensional dynamical systemsA0109mathematical physicsA010901Gauge field theory and string theoryA010902Integrable systems and their applicationsA0110Probability theory and stochastic analysis A011001Markov process and ergodic theoryA011002Stochastic analysis and stochastic process A011003stochastic differential equationA011004Limit theoryA0111mathematical statisticsA011101Sampling survey and experimental designA011102Time series and multivariate analysisA011103Data analysis and statistical calculation A0112Operations researchA011201Linear and nonlinear programmingA011202Combinatorial optimizationA011203Stochastic optimizationA011204reliability theoryA0113Mathematical methods in cyberneticsA011301Control theory of distributed parameter systems A011302Control theory of stochastic systemsA0114Applied mathematical methodA011401information theoryA011402Economic Mathematics and financial mathematics A011403Biological mathematicsA011404Mathematical theory of uncertaintyA011405Fractal and Its ApplicationsA0115Mathematical logic and computer related mathematics A011501mathematical logicA011502Axiomatic set theoryA011503Computational complexity and symbolic computation A011504Machine proofA0116CombinatoricsA011601Combinatorial designA011602graph theoryA011603Algebraic combination and combinatorial matrix theoryA0117Computational mathematics and scientific engineering computingA011701Numerical calculation of partial differential equationsA011702Numerical calculation in fluid mechanicsA011703Computation of general inverse problemsA011704Numerical calculation of ordinary differential equationsA011705Numerical algebraA011706Numerical approximation and computational geometry A011707Spectral method and high precision numerical method A011708Finite element method and boundary element method A011709Multigrid technique and domain decompositionA011710Adaptive methodA011711parallel algorithmA02DynamicsA0201Basic problems and methods in mechanicsA020101Mathematical methods in rational mechanics and mechanics A020102physical mechanicsA020103Inverse problems in mechanicsA0202Dynamics and controlA020201Analytical mechanicsA020202Bifurcations and chaos in dynamical systemsA020203Motion stability and its controlA020204Nonlinear vibration and its controlA020205Multibody system dynamicsA020206Rotor dynamicsA020207Ballistic mechanics and flight mechanicsA020208Dynamics of vehicle and its controlA020209Multi field coupling and dynamics of intelligent structures A0203solid mechanicsA020301Elasticity and plasticityA020302Damage and fracture mechanicsA020303Fatigue and reliabilityA020304Constitutive relationA020305Mechanics of composite materialsA020306Intelligent materials and structural mechanicsA020307Mechanical behavior of materials and structures in supernormal environmentsA020308NanoA020309Mechanics of contact, friction and wearA020310Surface, interface and thin film mechanicsA020311Rock mechanics and soil mechanicsA020312Structural mechanics and structural optimization A020313Vibration, noise and control of structuresA020314Fluid structure interaction mechanicsA020315Manufacturing process mechanicsA020316Experimental solid mechanicsA020317Computational Solid MechanicsA0204fluid mechanicsA020401Turbulence and flow stabilityA020402HydrodynamicsA020403AerodynamicsA020404Nonequilibrium flow and rarefied gas flow A020405Multiphase flow and seepage flowA020406Non Newtonian flow and rheologyA020407Flow noise and aerodynamic acousticsA020408Flow control and optimizationA020409Environmental fluid mechanicsA020410Industrial fluid mechanicsA020411microgravity fluid mechanicsA020412Traffic flow and particle flowA020413Electromagnetic and multi field coupled fluid mechanics A020414Experimental fluid mechanicsA020415Computational fluid dynamicsA0205biomechanicsA020501Tissue and organ system mechanicsA020502Cellular, subcellular, and biological macromolecular mechanicsA020503Bionics, biomaterials and Sports BiomechanicsA0206Explosion and shock dynamicsA020601Mechanics of explosionA020602Impact dynamicsA03AstronomyA0301cosmologyA030101The cosmological model and parameters, the early universeA030102The formation and evolution of the structure of the universe and observational cosmologyA030103The cosmic dark matter and dark energyA0302Galaxies and quasarsA030201The Milky Way DepartmentA030202The formation, structure and evolution of galaxiesA030203Galaxy interaction and coalescence; active galactic nucleiA0303The stars and interstellar materialA030301The structure and evolution of the stars and stellar atmosphereA030302Star and cataclysmic variables, binary and multiple starsA030303Star formation and early evolution of the interstellar medium, and interstellar moleculesA030304Advanced evolution and compact objects and related energetic processesA030305Extrasolar planetsA0304The sun and the solar system.A030401The solar magnetic field and solar generatorA030402Solar flares, coronal mass ejections, prominence and other activitiesA030403Helioseismology and the internal structure of the sun; sunspots and solar cycle variations in the sunA030404The planets and satellites in the solar system and the origin and evolution of the solar system and other small objectsA030405The impact of weather and solar activities on spaceA0305Theory and experiment of basic physical processes in celestial bodiesA030501The basic theoretical and experimental physics and astronomy in the astronomical radiation processA030502Laboratory astrophysicsA0306Astrometrical and astrogeodynamicsA030601Astronomical reference system and catalogA030602Relativistic AstrometryA030603Application of astrogeodynamics and astrometry.A030604Time and frequencyA0307Celestial mechanics and satellite dynamicsA030701The dynamics of man-made objects, small bodies in the solar system, the planets and solar systems systemA030702N body problem, nonlinear and relativistic celestial mechanicsA0308Astronomical techniques and methodsA030801Optical, ultraviolet and infrared astronomy technology and methodA030802Radio, millimeter wave and sub millimeter wave astronomy technology and methodA030803High energy astrophysics techniques and space astronomytechniques and methodsA030804Astronomical techniques and methods of massive data processing and numerical simulationA0309In the west, the history of astronomyA0310Cross with other disciplines of astronomyA04Physics IA0401Condensed matter of 1: structure, mechanical and thermal propertiesA040101Solid structure and Artificial MicrostructureA040102The structure and properties of soft material and liquidA040103Condensed state of materials mechanics, thermal properties, phase transition and lattice dynamicsA040104Condensed matter (non electronic) transport propertiesA040105The formation of thin films and nanostructuresA040106Characterization and analysis of surfaces, thin films and nanostructuresA040107Non electronic properties of surface and interface, system, mesoscopic nano systemA0402Condensed matter II: electronic structure, electrical, magnetic and optical propertiesA040201The electronic states of bulk materialsA040202Strongly correlated electron systemA040203Electron transport processes: conductance, photoconductivity, and magnetic conductivityA040204Electronic structures and electrical properties of surfaces, interfaces, and low dimensional systemsA040205Electronic structures, optical and electrical properties of mesoscopic systems and Artificial MicrostructuresA040206SuperconductivityA040207Magnetic ordered systemA040208Magnetic properties of low dimensional, mesoscopic and Artificial MicrostructuresA040209Dielectric, piezoelectric, thermoelectric, and ferroelectric propertiesA040210The interaction of radiation and condensed matter spectroscopy, and optical material and particlesA040211Condensed matter physics under extreme conditionsA040212Condensed matter physics in quantum computationA040213The electronic structure and physics of soft, organic and biological materialsA040214Condensed matter physics in the phenomenon of lifeA040215New effects and other problems in condensed matter physicsA0403Atomic and molecular physicsA040301Atomic and molecular structure theoryA040302Atomic, molecular and photon interactions and spectraA040303Processes and interactions of atomic and molecular collisionsA040304Properties of macromolecules, clusters and special atomic moleculesA040305Atomic and Molecular Physics under extreme conditionsA040306Properties and manipulation of atoms and molecules in anexternal fieldA040307The problems of atomic and molecular physics in quantum informationA040308Other physical problems associated with atoms and moleculesA0404opticsA040401Propagation and imaging of lightA040402Physical problems in Information OpticsA040403Physical problems in light sources, optical devices, and optical systemsA040404Physical problems in fiber optics and integrated opticsA040405Interaction of light and matterA040406Ultrafast and ultrafast light physicsA040407Micro nano optics and PhotonicsA040408Quantum optics and quantum informationA040409nonlinear opticsA040410Physical problems and solid luminescence in optical materialsA040411Laser spectroscopy and high resolution and high sensitive spectroscopic methodsA040412X ray, infrared and THz physicsA040413The application of optics in life scienceA040414Other physics problems and cross disciplines related to opticsA0405acousticsA040501Linear and nonlinear acousticsA040502Underwater acoustics and marine acoustics and aerodynamics acousticsA040503Ultrasonics, quantum acoustics, and acoustic effectsA040504Noise and noise effects and their controlA040505Physiological, psychological, acoustic, and biological acousticsA040506Speech acoustics, sound and acoustic signal processingA040507Acoustic transducers, acoustic measurement methods, and acoustic materialsA040508Acoustical problems in Information ScienceA040509A040510Architectural acoustics and electroacousticsOther physics and interdisciplinary subjects related to acousticsA05Physics IIA0501Basic physicsA050101Mathematical problems and computational methods in Physics A050102Classical physics and its phenomenological studyA050103Quantum physics and Its ApplicationsA050104Quantum information scienceA050105Statistical physics and complex systemsA050106Relativity, gravitation and CosmologyA0502Particle physics and field theoryA050201General theory and methods of fields and particlesA050202QCD, strong interaction and hadronic physicsA050203Electro weak interaction and its phenomenologicalA050204Nonstandard models and their phenomenological studiesA050205The spatial dimensions of string theory, and hidden film A050206Non accelerator particle physicsA050207Particle Astrophysics and CosmologyA0503nuclear physicsA050301Study on the structure and characteristics of nucleiA050302Highly excited states, high spin states and super deformations of nucleiA050303Nuclear fission, nuclear fusion, nuclear decayA050304Heavy ion nuclear physicsA050305Synthesis and reaction mechanism of radioactive nuclear beam physics, superheavy elementsA050306Intermediate and high energy nuclear physicsA050307nuclear astrophysicsA0504Nuclear technology and Its ApplicationsA050401Interaction of ion beam with matter and radiation damage A050402Ion beam nuclear analysis techniqueA050403Nuclear effect analysis techniqueA050404Neutron technology and Its ApplicationsA050405accelerator mass spectrometryA050406Ion implantation and modification of ion beam materials A050407Applications of nuclear technology in Environmental Science, geology and ArchaeologyA050408Application of nuclear technology in industry, agriculture and medicineA050409New concepts, principles, methodsA0505Particle physics and nuclear physics experimental methods and techniquesA050501Beam physics and accelerator technologyA050502Charged particle source, target station and pre acceleration deviceA050503Beam transmission and measurement technologyA050504Reactor physics and technologyA050505Related technologies of spallation neutron sourceA050506Detection technology and spectrometerA050507Radiation dosimetry and radiation protectionA050508Acquisition and processing of experimental dataA050509New principle, new method, new technology and new application A0506Plasma physicsA050601Basic processes and characteristics in plasmasA050602Plasma generation, heating, and confinement A050603Waves and instabilities in plasmasA050604Nonlinear phenomena in plasmasA050605Plasma interaction with matterA050606Plasma diagnosisA050607Strong particle beam and radiation source A050608Magnetically confined plasmaA050609Inertial confinement plasmaA050610Low temperature plasma and its applicationA050611Space and celestial bodies, plasmas, and special plasmasA0507Synchrotron radiation technology and Its ApplicationsA050701Principle and technology of synchrotron radiation light source A050702Principles and techniques of free electron lasersA050703Beam optics and experimental methods。
出国留学休学申请书7篇
出国留学休学申请书7篇出国留学休学申请书【篇1】Dear Professor __due to the comprehensiveness of china’s “reform and open” policies, economics plays an increasingly important role in the development of its global position. though more and more companies built, management of companies cannot catch up with the development of the companies. management is a burgeoning field in china, so i hope i can acquire more modern knowledge on management in england.the roots of my strong interest in business can be traced back to my childhood. my father was among the first of china’s new breed of modern entrepreneurs. as a young girl, it was inspirational hearing about his business ventures, and meeting the varied and interesting circle of entrepreneurs. my mother was also involved in business as an accountant, helping him with simple calculations. and so it was early in my life that i hoped i, also, would someday be able to enter the realm of business. with the time of growing up, i preferred reading books to satisfy my curiosity. i never ceased to contemplate over the questions i encountered. subjects on business and management became a special fascination to me and my knowledge of psychology as well as interest in this field was increasing rapidly.as a high school student in china, i had to concentrate on the college entrance examination (cee), even so, books not related to the exams were never excluded from my life. unfortunately when sitting in the exam in june, __, i was so nervous that i didn’t score well in the cee exam. i enrolled in the department of computer science in zhejiang college oftraditional chinese medicine. any attempt to persuade myself to focus on my major turned out to be a failure at the beginning of my college life. after several terms, i realized that i would never be interested in being a programmer or an engineer. at that moment, i lost my direction and objectives.my persistence in reading saved me from the dark situation. as a matter of fact, i enjoyed reading the books included encyclopedia american, and some books about management by peter f.drucker. i began to notice something interesting: why some companies can produce more than others? why some company can sell more than others? why some companies can build up but others cannot when facing the same difficulties?with the questions in my mind, i started to read many relevant books.i was lucky to read the book “jack: straight from the gut”by jack welch, in which john a. byrne makes a clear illustration that the management is important for a company. when i was a junior, i ran a bookshop by myself near my school. i should manage not only the finance in the shop but also the employees in my shop even made some strategies to enlarge the business in my shop to hold on the run the shop. from this, my interpersonal skills and the capacity in business has been greatly developed, definitely i was increasingly interested in what i was doing. by december, __, i had finally determined to take business management as my career instead of it. to accumulate more relevant knowledge, i strived to gain more practical work experience in some big companies.fortunately, as a senior, i began by conducting an internship in the architecture company in zhejiang province. over six months, i worked as an assistant of the manager to harmonize the relationship between the different departments in this company and to draft some management system, which broadened my perspective of management conditions and businessperformance in different industries. the experience showed me that management is much more important than that of i thought in big companies. after graduation, i continued my work in this company. in may, __, the company offered me an opportunity to participate in an training program held by a famous management school. through in-depth discussions with teachers and students in the classes, they all encouraged me to pursue my future career in management field because of my intellectual ability and the brand new ideas i mentioned.during the short period of training, i realized that pursuing a higher degree in management is a wise choice for me now. lancaster, with its excellence in management, represents the perfect fit for my needs. in your challenging environment, i can build the required foundation of knowledge related to management to achieve my goals. i am firmly convinced that your admission will be my first step of success. with this in mind, i hereby submit my application, and await your favorable reply.as a child i often accompanied my father to his small coin shop and spent hours watching him work. when i was older, i sometimes set up displays, waited on customers, and even balanced the books. this experience instilled in me the desire to own and manage my own business someday, yet i understand that the business world today is more complex. this complexity requires more education, and with that in mind, i am applying to the master’s of business administration program at indiana university bloomington (iub).出国留学休学申请书【篇2】Dear x,With the approach of new century, the developing China is requiring bettertrained and more highly educated men and women than ever before in history. Inorder to make more contributions to the society and, at thesame time, satisfymy keen interest in science, I am looking forward to beginning my graduatestudy. I heard of Case Western Reserve University as early as when I was anundergraduate student. She is one of the most highly regarded universities inthe world and is an ideal place for ambitious youth.I plan to study for Ph.D. in Biochemistry at Case Western ReserveUniversity with special interests in metabolism, macromolecular synthesis, andprotein crystal growth. I have had plentiful preparations. First, when being anundergraduate in the Department of Chemical Engineering at Tsinghua University,I got very extensive and intensive education. I took many courses on chemistryand the related subjects, and earned high scores for most of them. Second, mymajor, Polymer, can be put into good use in Biochemistry programs becausePolymer is closely related with biological Macromolecule. Third, I have workingexperience that enriches my theory and laboratory skills.From 1990 to now, I have been engaged as an Assistant Engineer by theResearch institute, Beijing Yanshan Petrochemical Corporation (RIBYPC). In thefirst year, I was in charge of a 5-litre reactor for polymerization ofCarboxylated Butadiene-Styene Latex. Then I was transferred to another researchgroup to synthesize PETPHB copolymer, a kin of polyester, which has theproperty of Liquid Crystal. I am the assistant head of the group. We can preparethe novel polymer with high molecule weight and excellent property in a 2-litrestainless steel reactor. During this monomers, with purity of more than 99.99%;this made my leader very satisfied.More than four years of working experiences expand my capacity. I oftenmake use of NMR, X-ray, DSC and other instrumental methods for research. Amongthem, I am most skilled in NMR reactors, I have experienceson solving problemsof Engineering and Mechanics. What is more, I am familiar with computeroperation and some application software. The above information about myspecialty may be helpful for you to evaluate me. It is said that the 21st century will be the age of Life Science. I hope toenter the esteemed Case Western Reserve University to face this challenge. I amconfident tat I shall be an excellent fellow. After completing my graduatestudy, I would like to return to my homeland and make use of my knowledge toserve the people.By the way, I would like to give thanks to my parents. Being their oldestson, I am offered the most formal education and the deepest love.I never forgetthe 18-year’s life with them. Twelve years in the countryside and six years inShengli Oil Field bestowed me the character of diligence, resolution, andperseverance, as well as the deep love of nature and life. I am also indebted tomy dear wife. Without her never-ended encouragement and support in these years,I could not become closer and closer to the gate of the eminent Case WesternReserve University.Knowing where is heading during navigation brings assured happiness. As astudent majoring in Biochemistry, I began my odyssey five years ago, when ourclass had a new biology teacher, who was young and energetic. He taught us in anentertaining way and communicated with us quite well. I liked him very much andwas impressed by the knowledge of Biological Sciences. He opened new doors tothe realm of Biology in my life. And with time being, I feel more and more sureabout my destination. Although the trail of navigation has not always beendefinitely straight, I believe it leads me to my dream.Because of my excellent performance in the National Olympic MathematicsContest of High School Students in 1994 and my outstanding academic record insenior high school, I had the opportunity to be admittedto Peking University orTsinghua University, two most selective universities in China, waived of theAdmission Examination. But if I took the chance, I couldn’t select biologicalsciences as my major. So I gave up the precious chance and took the AdmissionExamination. I succeeded and was admitted by the Department of Biochemistry andMolecular Biology in Peking University, which ranks first in biological scienceeducation and research in China and has raised many scholars including membersof Chinese Academy of Sciences. In the first three years in university, mycurriculum has a broad range, covering both natural and humanity sciences, aswell as putting emphasis not only on biological sciences but also on closelyrelated courses. I have dedicated my energy to my study and have received acomplete, profound and strict training in biological sciences with the combinedstrength of individual and professors help. Playing basketball is also a solidpart of my campus life. I am an active member in the basketball team of theCollege of Life Sciences in Peking University. As a point guard, the organizerof the teams attack, I have learned to make the five players to be a stronggroup in a game. Last year, we ranked the third in Peking University Cup amongthe thirty-six teams. This experience endows me a strong sense ofresponsibility, confidence and team-working spirit.To be a successful scientific researcher requires not only academicpotential but also independent research ability. A student will developcapability for independent research by working closely with a scholar. For thisreason, I entered the National Laboratory of Protein Engineering and PlantGenetic Engineering and participated the Group of Protein Structure andFunction. Now I cooperate with two graduate students, one of whom will go to theHarvard Medical School to continue his research work. Our ultimate goal is todevelop a new thrombolysis drug, which issupported by the National 863 Hi-TechPlanning. (Please check Research Experience for detail.) By the three monthshere, I have been able to do many experiments independently and have obtainedserious attitude and cooperation in scientific work.I have a sublime dream to be one equipped with exceptional experimentskills in addition to advanced scientific and technological knowledge. In mymind Pennsylvania State University is an ideal place to purse the graduatestudy, which is intellectually exhilarating and challenging. I respect yourrigorous scientific approach, original idea and outstanding achievements. I ameager to join a group in which I can make the best use of my capabilities andcombine my personal intelligence with group cooperation to full-fill the group’sbenefit as well as to make my dream come true. The Department of Pharmacology isdefinitely this type. With the fast development in the field of life sciences,human is getting more and more interested in probing into the nature of lifeitself and every great achievement in the study of life is sure to put light toour understanding of ourselves and to benefit our people and society as a whole.The field of Pharmacology has particular importance to serve man’s purposeabove. A scientist of Pharmacology is not only a researcher, but also thecreator of the future world. I think the challenging Pharmacology is the mostsuitable field for me to begin my graduate study, which is more than acontinuation of undergraduate study and is of not only a matter of greaterknowledge. The aim of it is to prepare students to enter a profession in whichthe knowledge is put into daily use. I am interested in the field of signalpathway in tumor formation. Several professors research impressed me, includingDr. Mulder and some other professors. After obtaining my Ph.D., I plan to doresearch work in an institution either domestically or overseas. I believe thatsuch a position providesthe largest room in which I can make the mostenthusiastic dedication to the world of sciences.I believe the advanced courses, distinguished faculty and thebest-equippedlaboratories of your group will help me make the desired achievements. With theconviction that I can sustain me through the intense graduate study, I have madethe decision to apply for Pennsylvania State University and hope your seriousconsideration.Yours sincerely出国留学休学申请书【篇3】澳洲留学文书写作要点一、围绕中心突出重点无论申请者选择怎样的事例，表达怎样的观点，首先都应考虑清楚，这些素材是否值得描述，与自己的申请目标、学术目标、职业目标甚至人生目标是否相关。