1 Utilizing Lamarckian Evolution and the Baldwin Effect in Hybrid Genetic Algorithms

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EvolutionUnit5Overview-MARRIC5概述-马立克进化单元

EvolutionUnit5Overview-MARRIC5概述-马立克进化单元

Evolution Unit 5 Overview - MARRIC5概述-马立克进化单元Name:____________________________________ Date:_____________Period:_____ Evolution Unit 5 – OverviewSchedule – February 11, 2009 through March 27, 2009; Unit Exam Tuesday 3/23/09Unit 5. Evolution Key Standards (2nd Semester)5a. The frequency of an allele in a gene pool of a populationdepends on many factors and may be stable or unstable over time.Students will apply how natural selection affects the characteristics of an organism and how mutations are maintained within a gene pool. (7a, 7b, 7c) Key Elements:1. Define the following concepts: natural selection, mutation, gene pool2. Describe the process of natural selection.3. Give an example of natural selection in nature.4. Explain how natural selection affects the characteristics of an organism.5. Explain how a mutation is formed.6. Discuss how a mutation is maintained within a gene pool.5b. The frequency of an allele in a gene pool of a populationdepends on many factors and may be stable or unstable over time. Evolution is the result of genetic changes that occur in constantlychanging environments. Students will describe how greater variationwithin a species may lead to greater survival of that species. (7d, 8b) Key Elements:1. Define variation, species.2. Explain how variation affects a species survival.3. Give a realistic example of how variation in a species has leadto its greater survival.5c. Evolution is the result of genetic changes that occur in constantly changing environments. Students will evaluate the effects of genetic drift and geographic isolation on a species. (8c, 8d) Key Elements:1. Define the following: genetic drift, gene pool, geographic isolation, and species2. Evaluate how genetic drift will affect a species, its gene pool, and its survival.3. Evaluate how geographic isolation will affect a species, its gene pool, and its survival. 5d. Evolution is the result of genetic changes that occur in constantly changing environments. Students will identify that analysis of fossil, DNA, and anatomical evidence supports evolution. (8e, 8f) Key Elements:1. Define the following: fossil, DNA, anatomical evidence, evolution, homologous structures, andanalogous structures.Evolution Unit Overview 12. Describe how fossil evidence supports evolution.3. Describe how DNA evidence supports evolution.4. Describe how anatomical evidence supports evolution.5. Give a realistic example of how all of the following support evolution: fossil evidence, DNA,and anatomical evidence.Note: The abbreviation CCS stands for California Content Standards referenced below.California Standards Evolution7. The frequency of an allele in a gene pool of a population depends on many factors and may be stable or unstable over time. As a basis for understanding this concept:a) Students know why natural selection acts on the phenotype rather than the genotype of anorganism.b) Students know why alleles that are lethal in a homozygous individual may be carried in aheterozygote and thus maintained in a gene pool.c) Students know new mutations are constantly being generated in a gene pool. d) Students know variation within a species increases the likelihood that at least some members ofa species will survive under changed environmental conditions.8. Evolution is the result of genetic changes that occur in constantly changing environments. As a basis for understanding this concept:a) Students know how natural selection determines the differential survival of groups oforganisms.b) Students know a great diversity of species increases the chance that at least some organismssurvive major changes in the environment.c) Students know the effects of genetic drift on the diversity of organisms in a population. d) Students know reproductive or geographic isolation affects speciation.e) Students know how to analyze fossil evidence with regard to biological diversity, episodicspeciation, and mass extinction.Textbook – Chapters 14 History of Life (pg 390 – 415) 15 Evolution (pg 416-449).Class Website – /teaching;Resources -, May 1998Tentative ScheduleWeek 1: 2/16 - 2/20 –President’s Day Holiday 2/16 Chapter 14 History of Life (due 2/23),Week 2: 2/23 - 2/27 –Unit 5 Quiz 1, Chapter 15 Evolutionary Processes (due on 3/5)Week 3: 3/2 - 3/6 – Unit 5 Quiz 2, Chapter 15 Evolution and Natural SelectionWeek 4: 3/9 - 3/13 – Unit 5 Quiz 3, Chapter 17 Classification and Review for ExamWeek 5: 3/16 - 3/20 – Breeding Bunnies and Molecular Clocks and Review for ExamWeek 6: 3/23 – 3/27 – Unit 5 Exam 3/24/00; Portfolio preparation Evolution Unit Overview 2"In the broadest sense, evolution is merelychange, and so is all-pervasive; galaxies,languages, and political systems all evolve.Biological evolution ... is change in theproperties of populations of organisms thattranscend the lifetime of a single individual. 1The ontogeny of an individual is notconsidered evolution; individual organisms donot evolve. The changes in populations thatare considered evolutionary are those thatare inheritable via the genetic material fromone generation to the next. Biologicalevolution may be slight or substantial; itembraces everything from slight changes inthe proportion of different alleles within apopulation (such as those determining bloodtypes) to the successive alterations that led 2from the earliest protoorganism to snails,bees, giraffes, and dandelions." Douglas J.Futuyma in Evolutionary BiologyWhat changes in evolution? Actually whatchanges is the frequency of an allele. Thefrequency of an allele in the gene pool of apopulation is how often an allele occurs inthe genotypes of individuals of the samespecies that are in the same area - thesame population. How often the alleleoccurs depends on lots of factors such as 1) what the allele codesfor - is it a critical trait for survival and 2) is the allele a dominant or a recessive allele. These factors determine whether the allele will be present for a long time or a short time. Naturalselection acts on population by changing the frequency of different alleles. If an allele is harmful, it will be eliminated from the population or reduced in its frequency because those individuals in the population exhibiting the trait will not survive. This leads to a fine difference between genotype and phenotype. Remember genotype is the kinds of genes an individual has and phenotype is its observable traits. It is the observable traits that are selected for or against resulting in increased allele frequency or reduced allele frequency, respectively. Since we are also considering genotypes, recall that the three ways that mutations happen most often are changes in the DNA (deoxyribonucleic acid) sequence due to insertions, deletions, or substitutions. It is very easy to get overly concerned about evolution if the focus is on human evolution. If instead the focus is on the mechanisms of how organisms change over time, a lot of emotional distress can be avoided. Being a Roman Catholic and believing that God created the Universe does not necessarily conflict with evolutionary theory. Evolution can be thought of as an accumulation of changes that occur within a population resulting from genetic and environmental changes. Within a population oforganisms of the same species there are differences between the individuals (variation). A species is a group of individuals that can interbreed and produce fertile offspring (offspring that can reproduce). The greater the variation between individuals the greater the likelihood that the species will survive if the environment changes.1 Ontogeny: the development of an individual from the moment the egg is fertilized up till adulthood.2 Protoorganisms: bacteria.Evolution Unit Overview 3Since the Earth was created, many environmental changes haveoccurred and some species have become extinct and others have apparently changed into different species. If an environment changes too much and there is not enough variation within the population, few if any individuals will survive the change, resulting in the species becoming extinct. But if there is sufficient variation so that some “weirdoes” can survive, then those will be the ones that can reproduce and their characteristic genes transmitted to the next generation. If there were a few before the change, then after the change they will be the majority apparently evolving into another species. Looking at fossils (mineralized remains of organisms) similarities can be observed. Paleontologists and evolutionary biologists have developed relationships between existing and extinct species by tracing anatomical and genetic similarities and differences.Besides mutations and large scale environmental changes, more minor changes can result in speciation. Speciation is the formation of a newspecies or group of organisms that can no longer interbreed with an original species population. These organisms no longer interbreed because their characteristics (either biological or behavioral) have become too different. This can happen randomly and by geographicisolation of a species. A random change in the kinds of genes in a population is called genetic drift. When populations of interbreeding individuals of the same species are large, the the allele frequency of each successive population is expected to vary little from the frequency of its parent population unless there are adaptive advantages associated with the alleles. But with a small breeding population (a group separated by geography), a change in even one individual can cause a disproportionately greater change in the population’s gene pool. Thereforesmall populations are more subject to genetic drift effects thanlarge populations. A situation exists when large populations are quickly reduced. This population reduction is called a population bottleneck. Like a bottleneck that is narrower than the bottle genetic variation is reduced. The reduced variation results in sudden changes in the allele frequency within the gene pool, and of the population’s characteristics. These type of changes are not gradual and called punctuated because sudden and drastic changes can occur. So evolutionary changes are not always slow (gradualism) or always rapid (punctuated equilibrium).Vocabulary1.Adaptation______________________________________________________________ ______________________________________________________________________ ____2. Analogousstructures________________________________________________________ ____________________________________________________________________ ____3. Anatomicalevidence_________________________________________________________4. ArtificialSelection__________________________________________________________ ____________________________________________________________________ ____5. DNA____________________________________________________________________6. Evolution_________________________________________________________________7.Embryology______________________________________________________________ _____________________________________________________________________ ____Evolution Unit Overview 48.Era_____________________________________________________________________ 9.Extinct_________________________________________________________________ __ 10. Fitness_________________________________________________________________ ____________________________________________________________________ ____ 11. Fossil___________________________________________________________________ ____________________________________________________________________ ____ 12. Foundereffect_____________________________________________________________ ____________________________________________________________________ ____ 13. Gene Pool________________________________________________________________ 14. GeneticDrift______________________________________________________________ ____________________________________________________________________ ____ 15. GeographicIsolation_________________________________________________________ 16. Geologic TimeScale_________________________________________________________ 17.Gradualism______________________________________________________________ ______________________________________________________________________ ____ 18.Interbreeding___________________________________________________________ __ 19. Homologousstructures_______________________________________________________ ____________________________________________________________________ ____ 20. MassExtinction____________________________________________________________ 21.Mimicry_________________________________________________________________ _ 22.Mutation________________________________________________________________ _ 23. Natural selection___________________________________________________________ ____________________________________________________________________ ____ 24.Paleontology____________________________________________________________ ___ 25.Period__________________________________________________________________ _ 26. Phenotype________________________________________________________________ 27.Population______________________________________________________________ _______________________________________________________________________ ____ Evolution Unit Overview 528. Punctuatedequilibrium_______________________________________________________ ____________________________________________________________________ ____ 29. Radioactive (radiometric)dating____________________________________________________________________________________________________________________ ____ 30. Relativedating_____________________________________________________________ ____________________________________________________________________ ____ 31. Reproductiveisolation________________________________________________________ ____________________________________________________________________ ____ 32. Survival of thefitness_______________________________________________________ ____________________________________________________________________ ____ 33.Speciation______________________________________________________________ ______________________________________________________________________ ____ 34.Species_________________________________________________________________ _ 35.Theory__________________________________________________________________ _ 36. Vestigial Structure(organ)____________________________________________________ ____________________________________________________________________ ____ 37.Variation_______________________________________________________________ __ 38.Darwin__________________________________________________________________ _ 39.Diversity_______________________________________________________________ __ 40. Indexfossil_______________________________________________________________ ____________________________________________________________________ ____ 41.Niche___________________________________________________________________ _ 42.Pesticide_______________________________________________________________ __ 43.Resistant_______________________________________________________________ __ 44.Variation_______________________________________________________________ __ 45. GalapagosIslands___________________________________________________________ Steps of Natural SelectionEvolution Unit Overview 6Evolution Unit Study Guide1. Evolution can be defined as any change in the relative frequency of alleles in the gene pool of a_____________________2. Differences between the members of a population will most likely be passed onto futuregenerations if they are3. Mutations that are lethal in homozygous individuals can survivein a population by being carriedbyA population of land snails colonized a field of yellow grass. At first, thepopulation contained two types of snails, one with brown bands on their shellsand another with yellow bands on their shells, as shown in thefigure below.After 10 years, most of the snails had shells with yellow bands.4. What process most likely led to an increase in the number ofsnails with yellow bands?5. What is the most likely reason that there are more yellow-banded snails present in thegrassland?A field of crops was sprayed with pesticides to control a population of insects that was eating the crop. Only 1% of the insects survived. The same amount and type of pesticide was sprayed on the field each year for the next 4 years. The graph below shows the percentage of insects that survived each year after the pesticide was used.6. Why was the pesticide less effective each year in its ability to control the target population ofinsects?7. change over evolutionary time.Evolution Unit Overview 78. In a species of plant, the sudden appearance of one plant with a different leaf structure wouldmost likely be the result of9. What would cause a mutation?10. In carrier pigeons there is a rare inherited condition that causes the death of the chicksbefore hatching. In order for this disease to be passed from generation to generation theremust be parent birds that11. Describe natural selection.12. The idea that evolution takes place at a continuous but very slow rate is knows as ______13. The idea that evolution takes place at one point in time, followed by a long period withoutchange is14. A genetic change will be maintained in a population if the change15. According to Darwin’s theory of natural selection, individuals who survive are the ones bestadapted for their environment. Their survival is due to the____________________________________________________________________ _16. When mountain lions prey on a herd of deer, some deer are killed and some escape. Which partof Darwin’s concept of natural selection might be used to describe this situation?17. A change in a sequence of DNA is called a18. Natural selection acts directly on19. If a mutation introduces a new skin color in a lizard population, what factor might determinewhether the frequency of the new allele will increase?_____________________________________________________________________20. genetic diversity provides a species with a higher probabilityof survivingchanges to its environment.21. The difference in the fur color of the individual species in a population is described as___________________________22. Two animals of different species would not be able to23. Spraying DDT to kill mosquitoes became less effective each year the pesticide was used. Thisdecrease in the effectiveness was probably caused by the fact that ______24. When penicillin was first introduced it was very effective in destroying most of the bacteriathat cause gonorrhea. Today, certain varieties of this bacterium are resistant to penicillin.Explain the presence of these penicillin resistant bacteria.Evolution Unit Overview 825. Although similar in many respects, two species of organisms exhibit differences that makeeach well adapted to the environment in which it lives. The process of change that may accountfor these differences is26.27. A random change in gene frequency in a small population is called28. Genetic drift is most likely to effect29. Geographic and reproductive isolation can result in30. A species of finch (a type of bird) has been studied on one of the geographically isolatedGalapagos Islands for many years. Since the island is small, the lineage of every bird forseveral generations is known. This allows a family tree of each bird to be developed. Somefamily groups have survived and others have died out. The groupsthat survive probably have31. A single species of squirrel evolved over time into two species, each on opposite sides of theGrand Canyon. This change was most likely due to32. All the genes of all members of a particular population make up the population’s ___________.33. Describe a gene pool.34. In genetic drift, allele frequencies change because of35. Genetic drift tends to occur in populations thatEvolution Unit Overview 936. A small population of chimpanzees lives in a habitat that undergoes no change for a long period.How will genetic drift probably affect this population?________________37. The separation of populations by barriers such as rivers, mountains, or bodies of water is called38. The geographic isolation of two populations of a species tends to increase differences betweentheir gene pools because it39. What kind of animal would be best adapted to survive extreme change in temperature?Comparisons are made between two different organisms by finding the place where the two lines intersect. The number where the columns and rows intersect shows how many amino acids are different in the cytochrome c of both organisms. For example, the number of amino acids that are different when comparing a rabbit's cytochrome c with a tuna's cytochrome c is 17. The larger thenumber, the greater the difference in the structure of the cytochrome c molecules of the twoorganisms.40. According to the table, which pair of organisms is least closely related?41. According to the table, which pair of organisms is most closely related?42. In a certain area of undisturbed layers of rock, fossils of horseshoe crabs may be found in theupper layer, and a lower layer contains fossils of trilobites. Trilobites are extinct aquaticarthropods resembling modern horseshoe crabs. This information suggests thatEvolution Unit Overview 1043. In the early stages of development, the embryos of dogs, pigs, and humans resemble eachother. This observation suggests that these animals may have44. An example of a structure that would be homologous to a birdwing would be a45. Fossil trees are petrified when the wood is replaced with46. The long, slow process of change in species over time is47. In humans, the pelvis and femur, or thigh bone, are involved in walking. In whales, the pelvisand femur shown in the figure above are48. Modern sea star larvae resemble some primitive vertebrate larvae. This similarity may suggestthat primitive vertebrates49. The number and location of bones of many fossil vertebrates are similar to those in livingvertebrates. Most biologists would probably explain this fact on the basis of __________________________________________________________________________ ___50. Individuals within a population of rabbits have different colors of fur as shown in the diagrambelow. The difference in the fur color of the individual rabbits is described as_____________________.51. What are three types of mutation?Sunny says Hi and Good Luck on your studies. Bunny out.Evolution Unit Overview 11。

用英文写一篇关于体内连续进化的综述文章

用英文写一篇关于体内连续进化的综述文章

用英文写一篇关于体内连续进化的综述文章Title: Evolution within the Body: A Comprehensive ReviewIntroduction: Evolution is a fascinating process that has shaped the diversity of life on Earth over millions of years. While the traditional concept of evolution primarily focuses on the genetic changes occurring across generations of organisms, there is growing evidence for another type of evolution that takes place within an individual's body. This phenomenon, known as "within-body evolution" or "somatic evolution," involves genetic changes occurring within the cells of an organism during its lifetime. In this review, we will explore the concept of within-body evolution, its underlying mechanisms, its importance in various contexts, and its potential implications for our understanding of biology.Mechanisms of Within-Body Evolution: Unlike traditional evolution, which operates through natural selection and genetic variation across generations, within-body evolution arises due to mutation and selection within the cells of an individual's body. Various factors contribute to this process, including DNA replication errors, environmental influences, and selective pressures exerted by the surrounding tissue microenvironment. These mechanisms give rise to genetic mosaicism, where different cells within an organism possess distinct genotypes.Within-Body Evolution and Disease: Within-body evolution is closely associated with the development and progression of diseases such ascancer. Somatic mutations accumulated over an individual's lifetime can lead to the initiation of tumor formation and the emergence of genetically diverse cancer cell populations. This diversity enables tumors to adapt and evolve in response to selective pressures such as therapeutic interventions. Understanding within-body evolution in the context of diseases is crucial for developing improved diagnostics, treatment strategies, and personalized medicine approaches.Impact on Development and Aging: Within-body evolution also plays a critical role in development and aging. The accumulation of somatic mutations over time can contribute to tissue dysfunction, age-related diseases, and the aging process itself. Additionally, somatic evolution influences cellular plasticity, allowing for tissue regeneration and repair. Studying within-body evolution provides insights into the mechanisms governing tissue homeostasis, regeneration, and cellular reprogramming.Evolutionary Implications: The recognition of within-body evolution raises intriguing questions about the relationship between the individual and its evolving cell populations. How does within-body evolution affect the overall evolutionary trajectory of a species? Can these accumulated genetic changes be passed on to future generations? Exploring these questions may enhance our knowledge of the genetic contributions to evolution and the complexities of multicellular organisms.Technological Advances and Future Directions: Advancements in DNA sequencing technologies, single-cell genomics, and computational analysis have revolutionized our ability to study within-body evolution in unprecedented detail. By characterizing the genetic landscapes of individual cells, researchers can uncover the dynamics, origins, and consequences of within-body evolution. Integrating large-scale genomic datasets with experimental models and mathematical modeling will further elucidate the underlying processes and functional implications of within-body evolution.Conclusion: Within-body evolution represents a paradigm shift in our understanding of the evolutionary process, emphasizing the importance of genetic changes occurring within an individual's lifetime. The study of within-body evolution not only sheds light on diseases like cancer but also contributes to our understanding of development, aging, and tissue homeostasis. As technology advances, further exploration of within-body evolution will undoubtedly unravel new insights into the intricacies of evolution and the complexity of life.This comprehensive review aims to provide a broad overview of within-body evolution, highlighting its mechanisms, implications for health and aging, evolutionary implications, and future directions of research. Continued investigation in this field promises to provide valuable insights into the dynamic nature of life and open new avenuesfor scientific exploration.标题: 体内连续进化:综述性论文介绍: 进化是一个令人着迷的过程,它在地球上塑造了数百万年来的生命多样性。

分子进化

分子进化

Two Basic Theories
Neutural selection
Two Basic Theories
The rate of random fixation of neutral mutations in evolution is equal to the rate of occurrence of neutral mutations If most DNA species divergence were due to adaptive Natural selection is the editor, rather than evolution, then one should expect that the first two thenucleotide position of eachgenetic message. One composer, of the codon would change more rapidly than the third position. thing the editor does not do is to remove But if which it is unable to preceive. changesDNA divergence in evolution includes the random fixation of neutral mutations, then the third-position nucleotides should change more rapidly.
Two Basic Theories
Molecular Clock Hypothesis
The molecular clock hypothesis asserts that the rate of amino acid or nucleotide substitution is approximately constant over evolutionary time, although the actual number of substitutions is subject to stochastic errors.

研究生英语精读教程第三版下第三单元

研究生英语精读教程第三版下第三单元

Unit Three Evolution and Natural Selection[1]The idea of evolution* was known to some of the Greek philosophers. By the time of Aristotle①, speculation* had suggested that more perfect types had not only followed less perfect ones but actually had developed from them. But all this was guessing; no real evidence was forthcoming*. When, in modern times, the idea of evolution was revived*, it appeared in the writings of the philosophers – Bacon①, Descartes②, Leibniz③ and Kant④. Herbert Spencer① was preaching* a full evolutionary doctrine* in the years just before Darwin's② book was published, while most naturalists would have none of it. Nevertheless a few biologists ran counter to the prevailing* view, and pointed to such facts as the essential unity of structure in all warm-blooded animals.[2]The first complete theory was that of Lamarck①(1744~1829), who thought that modifications* due to environment, if constant and lasting, would be inherited and produce a new type. Though no evidence for such inheritance was available, the theory gave a working hypothesis* for naturalists to use, and many of the social and philanthropic* efforts of the nineteenth century were framed on the tacit* assumption that acquired improvements would be inherited.[3]But the man whose book gave both Darwin and Wallace the clue was the Reverend* Robert Malthus① (1766~1834),sometime curate* of Albury in Surrey. The English people were increasing rapidly, and Malthus argued that the human race tends to outrun its means of subsistence* unless the redundant* individuals are eliminated. This may not always be true, but Darwin writes:[4]In October 1838,I happened to read for amusement Malthus on Population, and being well prepared to appreciate the struggle for existence which everywhere goes on, from long continued observation of the habits of animals and plants, it at once struck* me that, under these circumstances, favorable variations* would tend to be preserved, and unfavorable ones to be destroyed. The result of this would be the formation of new species. Here then I had a theory by which to work.[5]Darwin spent twenty years collecting countless facts and making experiments on breeding* and variation in plants and animals. By 1844 he had convinced himself that species are not immutable*, but worked on to get further evidence. On 18 June 1858 he received from Alfred Russell Wallace a paper written in Ternate, in the space of three days after reading Malthus's book. Darwin saw at once that Wallace had hit upon the essence of his own theory. Lyell① and Hooker②arranged with the Linnaean③Society to read on July 1st 1858 Wallace's paper together with a letter from Darwin and an abstract* of his theory written in 1844.Then Darwin wrote out an account of his labors, and on 24th November 1859 published his great book The Origin of Species.[6]In any race of plants or animals, the individuals differ from each other in innate* qualities. Darwin offered no explanation of these variations, but merely accepted their existence. When the pressure of numbers or the competition for mates* is great, any variation in structure which is of use in the struggle has "survival value" and gives its possessor an improved chance of prolonging life and leaving offspring. That variation therefore tends to spread through the race by the elimination of those who do not possess it, and a new variety or even species may be established. As Huxley said, this idea was wholly unknown till 1858.Huxley① said the book was like a flash of lightning in the darkness. He wrote:It did the immense service of freeing us from the dilemma - Refuse to accept the Creation hypothesis, and what have you to propose that can be accepted by any cautious reasoner? In 1857 I had no answer ready, and I do not think anyone else hadA year later we reproached* ourselves with dullness for being perplexed* with such an enquiry. My reflection* when I first made myself master of the central idea of the Origin was " How extremely stupid not to have thought of that!"[7]The hypothesis of natural selection may not be a complete explanation, but it led to a greater thing than itself - an acceptance of the theory of organic* evolution, which the years have but confirmed. Yet at first some naturalists joined the opposition. To the many, who were unable to judge the biological evidence, the effect of the theory of evolution seemed incredible as well as devastating*, to run counter to common sense and to overwhelm* all philosophic and religious landmarks. Even educated man, choosing between the Book of Genesis and the Origin of Species, proclaimed* with Disraeli① that he was "on the side of the Angels".[8]Darwin himself took a modest view. While thinking that natural selection was the chief cause of evolution, he did not exclude Lamarck's idea that characters acquired by long use or disuse might be inherited, though no evidence seemed to be forthcoming. But about 1890 Weismann①drew a sharp distinction between the body (or soma) and the germ cells which it contains. Somatic cells can only reproduce cells like themselves, but germ* cells give rise not only to the germ cells of a new individual but to all the many types of cell in his body. Germ cellsdescend from germ cells in a pure line of germ plasm,but somatic cells trace their origin to germ cells. From this point of view, the body of each individual is an unimportant by-product of his parents’ ger m cells. The body dies, leaving no offspring, but the germ plasms show an unbroken continuity. The products of the germ cells are not likely to be affected by changes in the body. So Weismann's doctrine offered an explanation of the apparent noninheritance of acquired characters.[9]The supporters of pure Darwinism came to regard the minute variations as enough to explain natural selection and natural selection enough to explain evolution. But animal breeders and horticulturists* knew that sudden large mutations* occur, especially after crossing, and that new varieties might be established at once. Then in 1900 forgotten work by Mendel①was rediscovered and a new chapter opened.[10]In 1869 Darwin's cousin, Francis Galton①, applied these principles to mental qualities. By searching books of reference, Galton examined the inheritance of ability. For instance, he found that the chance of the son of a judge showing great ability was about 500 times as high as that of a man taken at random, and for the judge's father it was nearly as much. While no prediction can be made about individuals, on the average of large numbers, the inheritance of ability is certain.Ⅰ. ComprehensionAnswer the following questions or complete the following statements by choosing the best alternative A, B, C or D under each. You are allowed 2 minutes 30 seconds for this part.1. From para.[1],it may be inferred that _______.A.philosophers were more sensitive than naturalistsB.Darwin's idea was based on Spencer'sC.the essential unity of structure in animals may prompt speculations about evolutionD.the prevailing view refers to Darwin's evolution2. Which of the following is not true?marck was one of the first scientists to attempt an explanation for the causes ofevolution.B.According to Lamarck, athletes develop their muscles by constant exercise and themuscular athlete will produce offspring whose muscles are well developed.marck's theory seemed reasonable.marck's theory was fully accepted by naturalists.3. Malthus's population theory _______.A.was the origin of Darwin's idea of evolutionB.was established from observation of the habits of animals and plantsC.stimulated Darwin's idea of natural selectionD.convinced Darwin that evolution has occurred4. Para.[5]suggests all the following except ______.A.Darwin was a methodical manB.Wallace was as impulsive as Darwin was deliberateC.Wallace found Darwin's work after many yearsD.Darwin's painstaking effort to document his views would have been extendedconsiderably but for the work of Wallace.5. Para.[6]mainly explained ______.A.the source of variationB.the idea of natural selectionC.the difference between favorable plants and animals and unfavorable onesD. the competition of animals6. Huxley ______.A.was reluctant to accept the Creation hypothesis but couldn’t offer another satisfyinganswer to the problemB.fully accepted Darwin’s ideaC.thought Darwin’s natural selection was a very simple ideaD.all of the above7. Which of the following is most likely to be the main reason why the public opposed Darwin’s theory?A.They lacked knowledge of biology.B.They were disturbed by gaps in the theory.C.The idea that humans developed from some subhuman creature outraged them.D.They found the evidence for the theory not convincing.8. What is the main idea of the last three paragraphs?A.Darwin’s theory of evolution was out of date.B.The conflict between Darwinism and anti-Darwinism.C.Strong objections were expressed against Darwin’s concept of organic evolution.D.There were weaknesses in Darwin’s theory and new theories were forming.9. What was not explained by Darwin?A.Variation within a species is common.B.New species can develop, either in one generation or gradually over many generations.C.New species may arise from former ones.anisms that are best suited to adapt to environmental changes will survive.Ⅱ. VocabularyA. Identify one of the four choices A, B, C, or D which would keep the meaning of the underlined word or phrase.1. Henry Ⅵ was an overwhelming success, perhaps partially because Shakespeare drew characters from actual English history.A. greatB. AmazedC. unexpectedD. unbelievable2. The new communication system is by no means a minute invention.A. insignificantB. minusculeC. accidentalD. significant3. On the notice board there was a list of forthcoming events at school.A. excitingB. arisingC. warningD. approaching4. In the Pacific Northwest, as climate and topography vary, so do the species that prevail in the forests.A. coexistB. invadeC. dominateD. gather5. Behind him were the ruins of a city, shattered, devastated, crumbled piles of concrete and stone that glowed.A. burntB. ravagedC. isolatedD. conquered6. Revision of technical prose requires word by word review and elimination of whatever is redundant.A. talkativeB. profuseC. abundantD. wordy7. In the last chapter I proposed the hypothesis that a pure poetry-exists, employing the term "lyric“ to describe poems which "consist of poetry and nothing else".A. conjectureB. deductionC. inferenceD. supposition8. Tacit parental approval should be obtained before marriage.A. tactfulB. permissiveC. intactD. implicit9. Then he sat and thought in the concentrated, abstracted way he has almost forgetting my presence.A. preoccupiedB. observantC. intentD. careful10. An Alexandrian speculator finally thought of a way of turning cat mummies into money.A. spectatorB. observerC. businessmanD. magicianB. Choose the correct answer. Only one answer is correct.11. These demands _____ the agreements we have reached.A. run away fromB. go against toC. go counter toD. act counter from12. Mary’s _____ was whether to go to the party in her old dress or to stay at home.A. plightB. emergencyC. dilemmaD. jam13. In temperate regions the growth rings on turtles’ epidermal plates ____ seasonal variations in growth.A. stimulateB. reflectC. includeD. prevent14. When new math was introduced into schools, many parents were _____ by the approach it involved.A. interestedB. enjoyedC. perplexedD. informed15. Most of the great European thinkers of the eighteenth and early nineteenth centuries helped to _____ the conception Shaftesbury first formulated.A. developB. involveC. discoverD. grow16. It is unfair for the manager to ____ the typist for being late, because she has been ill for a week.A. adviseB. reproachC. reviveD. strike17. A vast cigar-shaped body of gas was raised and eventually _____ from the surface of the sun.A. descendedB. outrunC. abstractedD. reflected18. What a coincidence! It _____ me only this very morning that we hadn't seen each other for twenty years.A. hit onB. struckC. reproachedD. reflected on19. Many people mistake a familiar for a vulgar style, and suppose that to write without affectation is to write _____.A. overwhelminglyB. at randomC. in the abstractD. cautiously20. His opinions were _____ and easily influenced by anyone who had any powers of persuasion.A. reflectiveB. speculativeC. strikingD. startlingⅣ. TranslationA. Put the following into Chinese.If one considers the enormous variety of courses offered, it is not hard to see how difficult it is for a student to select the course most suited to his interests and abilities. If a student goes to university to acquire a broader perspective of life, to enlarge his ideas and to learn to think for himself, he will undoubtedly benefit. School often has too restricting atmosphere, with its timetable and disciplines, to allow him much time for independent assessment of the work he is asked to do. Most s tudents would, I believe, profit by a year or so’s exploration of different academic studies, especially those “all-rounders” with no particular interest.B. Put the following into English.1. 聪明的动物依情况或环境的需要而改变自己的行为,但人类能有意识地改变自己的行为。

高中英语世界著名科学家单选题50题

高中英语世界著名科学家单选题50题

高中英语世界著名科学家单选题50题1. Albert Einstein was born in ____.A. the United StatesB. GermanyC. FranceD. England答案:B。

解析:Albert Einstein(阿尔伯特·爱因斯坦)出生于德国。

本题主要考查对著名科学家爱因斯坦国籍相关的词汇知识。

在这几个选项中,the United States是美国,France是法国,England是英国,而爱因斯坦出生于德国,所以选B。

2. Isaac Newton is famous for his discovery of ____.A. electricityB. gravityC. radioactivityD. relativity答案:B。

解析:Isaac Newton 艾萨克·牛顿)以发现万有引力gravity)而闻名。

electricity是电,radioactivity是放射性,relativity 是相对论,这些都不是牛顿的主要发现,所以根据对牛顿主要成就的了解,选择B。

3. Marie Curie was the first woman to win ____ Nobel Prizes.A. oneB. twoC. threeD. four答案:B。

解析:Marie Curie 居里夫人)是第一位获得两项诺贝尔奖的女性。

这题主要考查数字相关的词汇以及对居里夫人成就的了解,她在放射性研究等方面的贡献使她两次获得诺贝尔奖,所以选B。

4. Thomas Edison is well - known for his invention of ____.A. the telephoneB. the light bulbC. the steam engineD. the computer答案:B。

解析:Thomas Edison( 托马斯·爱迪生)以发明电灯(the light bulb)而闻名。

初二科学与人类未来英语阅读理解20题

初二科学与人类未来英语阅读理解20题

初二科学与人类未来英语阅读理解20题1<背景文章>Artificial intelligence (AI) is playing an increasingly important role in the field of healthcare. AI has the potential to revolutionize the way we diagnose and treat diseases.One of the main applications of AI in healthcare is in medical imaging. AI algorithms can analyze medical images such as X-rays, CT scans, and MRIs to detect diseases and abnormalities. This can help doctors make more accurate diagnoses and provide better treatment plans.Another application of AI in healthcare is in drug discovery. AI can analyze large amounts of data to identify potential drug candidates and predict their efficacy and safety. This can speed up the drug discovery process and lead to the development of new treatments for diseases.AI also has the potential to improve patient care. For example, AI-powered chatbots can answer patient questions and provide support, while AI-powered wearable devices can monitor a patient's health and alert doctors if there are any problems.However, there are also some potential risks associated with the use of AI in healthcare. One concern is that AI algorithms may not be accurate or reliable. If an AI algorithm makes a mistake, it could lead to incorrectdiagnoses or treatment plans. Another concern is that AI could lead to job losses in the healthcare industry. As AI becomes more advanced, it may be able to perform tasks that are currently done by humans, such as diagnosing diseases and prescribing medications.Despite these potential risks, the benefits of AI in healthcare are significant. As technology continues to advance, we can expect to see even more applications of AI in healthcare in the future.1. What is one of the main applications of AI in healthcare?A. Medical research.B. Medical imaging.C. Patient care.D. Drug development.答案:B。

小学下册第十四次英语第3单元期末试卷

小学下册第十四次英语第3单元期末试卷

小学下册英语第3单元期末试卷英语试题一、综合题(本题有100小题,每小题1分,共100分.每小题不选、错误,均不给分)1.I always brush my ______ before bed.2.Plants can be ______ (修剪) for shape and health.3.I enjoy ___ (building) with blocks.4.The fish swims in the ______ (water).5.I have a toy ________ that can soar through the air.6.Water freezes at ______ degrees Celsius.7.历史上,________ (pharaohs) 是古埃及的统治者。

8.What do we call a collection of books?A. LibraryB. BibliographyC. AnthologyD. Archive答案:A Library9.How many sides does a square have?A. ThreeB. FourC. FiveD. Six10.The __________ (环境科学) informs conservation efforts.11.I have a ________ for my birthday.12.I have a favorite ________ that helps me create.13.The __________ (历史的教诲) is invaluable.14.We have a ______ (愉快的) gathering for school events.15.What is the term for a human's outer covering?A. SkinB. MuscleC. BoneD. Fat答案:A16.The color of an object is determined by the wavelengths of light it ______.17.Many flowers bloom in __________ (春天).18.The parade was very ___ (exciting).19.My friend has a pet ______ (兔子) that is very fluffy.20.What is the process of plants making their own food called?A. DigestionB. PhotosynthesisC. RespirationD. Fermentation答案:B Photosynthesis21.为下列对话选择相符的图片。

evolution running 阅读理解

evolution running 阅读理解

Evolution Running: Improving Your Running Technique Running is a popular form of exercise due to its simplicity and numerous health benefits. However, many runners struggle to maintain proper form and efficiency, which can lead to discomfort, injuries, and suboptimal performance. Evolution Running is a technique aimed at improving running efficiency and reducing the risk of injuries. In this article, we will delve into the principles and benefits of Evolution Running.What is Evolution Running?Evolution Running is a methodology developed by Ken Mierke, a running coach and physical therapist. It is based on the idea that humans are naturally designed to run efficiently, and by adhering to certain principles, we can tap into our primal running instincts. The technique emphasizes posture, body alignment, and a midfoot strike as the key elements of efficient running.Posture and AlignmentA vital aspect of Evolution Running is maintaining proper posture and alignment during the run. Proper posture involves keeping the head, shoulders, hips, and feet in alignment, allowing for efficient movement and improved balance. By leaning slightly forward from the ankles, the body’s center of gravity aligns with the foot strike, reducing the stress on joints and muscles.Midfoot StrikeEvolution Running advocates for a midfoot strike, which means landing on the middle part of the foot, between the heel and toes. This technique helps to attenuate the impact of each stride and engages the body’s natural shock-absorbing mechanisms, such as the arches of the feet and the Achilles tendon. Moving away from a heel strike reduces the risk of injuries such as shin splints and stress fractures.CadenceAnother key aspect of Evolution Running is maintaining an optimal cadence, which is the number of steps taken per minute. It is recommended to aim for a cadence of around 180 steps per minute, as a higher cadence can lead to more efficient running. A high cadence helps to reduce overstriding, promotes a faster turnover of legs, and minimizes the braking forces acting on the body with each stride.Benefits of Evolution Running1.Improved Running Efficiency: By focusing on posture, alignment, anda midfoot strike, Evolution Running helps to maximize the body’s energytransfer and reduce wastage of movement. This increased efficiency allows fora faster and more effortless running experience.2.Reduced Risk of Injuries: The technique promotes proper foot strikeand alignment, which can minimize the stress on joints and muscles, reducing the likelihood of common running injuries. Evolution Running also discourages overstriding, a common mistake that can lead to various issues.3.Increased Speed: The emphasis on proper form and optimal cadencecan lead to improved running speed. With increased efficiency and reducedwasted energy, runners may find themselves completing their runs in shorter times.4.Enhanced Endurance: Evolution Running aims to conserve energy andreduce fatigue by focusing on efficient running mechanics. This can lead toimproved endurance levels, allowing runners to go the distance without feeling as tired or depleted.ConclusionEvolution Running offers a comprehensive approach to improving running technique and efficiency. By emphasizing posture, alignment, midfoot strike, and cadence, runners can reduce the risk of injuries, increase speed, and enhance endurance. Whether you are a seasoned runner or just getting started, integrating Evolution Running principles into your training can help you reach your full running potential.。

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Utilizing Lamarckian Evolution and the Baldwin Effect inHybrid Genetic AlgorithmsChristopher R. Houck - chouck@Jeffery A. Joines - jjoine@Michael G. Kay1 - kay@Box 7906Dept. of Industrial EngineeringNorth Carolina State UniversityRaleigh N.C. 27695-7906(919) 515-2008(919) 515-1543 FAXAbstract — Genetic algorithms(GA) are very efficient at exploring the entire search space; how-ever, they are relatively poor at finding the precise local optimal solution in the region at which the algorithm converges. Hybrid genetic algorithms are the combination of improvement proce-dures, usually working as evaluation functions, and genetic algorithms. There are two basic strat-egies in using hybrid GAs, Lamarckian and Baldwinian learning. Traditional schema theory does not support Lamarckian learning, i.e., forcing the genetic representation to match the solution found by the improvement procedure. However, Lamarckian learning does alleviate the problem of multiple genotypes mapping to the same phenotype. Baldwinian learning uses improvement procedures to change the fitness landscape, but the solution that is found is not encoded back into the genetic string. This paper empirically examines the issues of using Lamarckian and Baldwin-ian learning in hybrid GAs. In the empirical investigation conducted, a general trend was observed where increasing use of Lamarckian learning led to the quicker convergence of the genetic algorithm to the best known solution for a series of test problems.Keywords - Lamarckian Evolution, Baldwin Effect, Local Improvement Procedures, Hybrid GAs1 - Corresponding authorI.I NTRODUCTIONGenetic algorithms (GAs) are a powerful set of global search techniques that have been shown to produce very good results on a wide class of problems. Genetic algorithms search the solution space of a function through the use of simulated “Darwinian” evolution, i.e., the survival of the fittest strategy. In general, the fittest individuals of any population tend to reproduce and survive to the next generation, thus improving successive generations. However, inferior individuals can, by chance, survive and also reproduce. Genetic algorithms have been shown to solve linear and nonlinear problems by exploring all regions of the state space and exponentially exploiting prom-ising areas through mutation, crossover, and selection operations applied to individuals in the population. Whereas traditional search techniques use characteristics of the problem (objective function) to determine the next sampling point (e.g., gradients, Hessians, linearity and continuity), GAs make no such assumptions. Instead, the next sampled points are determined based on sto-chastic sampling/decision rules, rather than a set of deterministic decision rules. Therefore, evalu-ation functions of many forms can be used, subject to the minimal requirement that the function can map the population into a partially ordered set. A more complete discussion of genetic algo-rithms, including extensions and related topics, can be found in the books by Davis[6], Goldberg[7], and Michalewicz[18].This paper examines the use of genetic algorithms utilizing local improvement procedures (LIPs) to solve a wide class of problems. Section II describes how GAs can be hybridized by incorporat-ing local improvement procedures into the algorithm. Incorporating local improvement proce-dures gives rise to the concepts of Larmarckian evolution and the Baldwin Effect which are explained in Section II. Also, the concept of a one-to-one genotype to phenotype mapping is introduced, where genotype refers to the space the GA searches while the phenotype refers to the space of the actual problem. The concepts of Section II are tested in Section III on three different classes of problems: multi-modal continuous function optimization, the location-allocation prob-lem, and the manufacturing cell formation problem. The hybrid-GA is shown to be a very effi-cient and effective optimization method, especially when a one-to-one mapping is enforced (i.e., Larmarckian evolution is employed).II.H YBRIDIZING GA S WITH L OCAL I MPROVEMENT P ROCEDURESMany researchers [1,3,6,12,14,18] have shown that GAs perform well for global searchingbecause they are capable of quickly finding and exploiting promising regions of the search space, but they take a relatively long time to converge to a local optimum. Local improvement proce-dures, e.g., two-opt switching for combinatorial problems and gradient descent for unconstrained nonlinear problems, quickly find the local optimum of a small region of the search space, but are typically poor global searchers. Local improvement procedures have been incorporated into GAs in order to improve the algorithm’s performance through what could be termed “learning.” Such hybrid GAs have been used successfully to solve a wide variety of problems [1,6,12,14].There are two basic models of evolution that can be used to incorporate learning into a GA: the Baldwin Effect and Lamarckian evolution. The Baldwin Effect allows an individual’s fitness (phenotype) to be determined based on learning, i.e., the application of local improvement. Like natural evolution, the result of the improvement does not change the genetic structure (genotype) of the individual. Lamarckian evolution, in addition to using learning to determine an individuals fitness, changes the genetic structure of an individual to reflect the result of the learning. Both “Baldwinian learning” and “Lamarckian learning” have been investigated in conjunction with hybrid GAs.A. Baldwin EffectBaldwinian learning utilizes a LIP to determine the fitness of an individual; however, the genetic structure of the individual is not changed to reflect the application of the LIP. The Baldwin Effect, as utilized in genetic algorithms, was first investigated by Hinton and Nolan [9] using a flat land-scape with a single well representing the optimal solution. Individuals were allowed to improve by random search, which in effect transformed the landscape to include a funnel around the well. Hinton and Nolan showed that without learning the genetic algorithm fails; however, with the ran-dom search the GA is capable of finding the optimal.Whitley et al. [22] demonstrate that “exploiting the Baldwin Effect need not require a needle in a haystack and improvements need not be probabilistic.” They show how using a LIP can in effect change the landscape of the fitness function into flat landscapes around the local basins. This transformation increases the likelihood of allocating more individuals to certain basins or local optima. In a comparison of Baldwinian and Lamarckian learning, Whitley et al.[22] show that utilizing either form of learning is more effective than the standard GA approach without the local improvement procedure (a bitwise steepest ascent algorithm performed on a binary representa-tion). Whitley et al. [22] argue that, while Lamarckian learning is faster, it may be suspectable to premature convergence to a local optimum as compared to Baldwinian learning. Three numerical optimization problems were used to test this conjecture; however, the results were inconclusive.They believe that these test functions were too easy and that harder problems may in fact show that a Baldwinian search strategy is preferred.B. Lamarckian EvolutionLamarckian learning forces the genotype to reflect the result of some form of improvement. This results in the inheritance of acquired or learned characteristics that are well adapted to the envi-ronment. The improved individual is placed back into the population and allowed to compete for reproductive opportunities. However, Lamarckian learning inhibits the schema processing capa-bilities of genetic algorithms [8,21,22]. Changing the genetic information in the chromosomes results in a loss of inherited schema, altering the statistical information about hyperplane parti-tions implicitly contained in the population.While Lamarckian learning may disrupt the schema processing of a genetic algorithm, Baldwin-ian learning certainly aggravates the problem of multiple genotype to phenotype mappings. A genetic algorithm works on both genotypes and phenotypes. A genotype refers to the composition of the values in the chromosome or individual in the population. Whereas a phenotype refers to the solution that is constructed from a chromosome. In a direct mapping, there is no distinction between genotypes and phenotypes. For example, to optimize the function , a typical representation for the chromosome would be a vector of real numbers (x 1, x 2), which pro-vides a direct mapping to the phenotype. However, in some problem instances, a direct mapping is not possible or desired [19]. The most common example of this is the TSP problem with an ordinal representation. Here, the genotype is represented by an ordered list of n cities to visit, e.g.,(c [1]c [2]...c [n ]). However, the phenotype of the TSP is a tour, and any rotation of the chromosome yields the same tour; thus, any rotation of a genotype results in the same phenotype. For example,the two tours (1,2,3,4) and (3,4,1,2) have different genotypes since their gene strings are different,but both strings represent the same tour and thus have the same phenotype.It has been noted that having multiple genotypes map to the same phenotype may confound the GA [10,19]. This problem also occurs when a LIP is used in conjunction with a GA. Consider the example of optimizing . Suppose a simple gradient based LIP is used to determine the fitness5x cos 12sin x 2–x sinof a chromosome. Then any genotype between [-π/2, 3π/2] will have the same phenotype value of 1 atπ/2.III.E XPERIMENTATIONTo investigate the trade-off of disrupted schema processing in Lamarckian learning and of multi-ple genotype mapping to the same phenotype in Baldwinian learning, a series of experiments using LIPs as evaluation functions were run on several different test problems. For each test prob-lem the GA was run with a varying levels of chromosome “forcing” after the evaluation. The GA was run with no forcing (i.e., a pure Baldwinian search strategy), denoted 0% update, as well as 100% forcing (i.e., a pure Lamarckian search strategy). Combinations of both strategies were used to determine if there was a trend between the two extremes, or if combinations of Baldwin-ian learning and Lamarckian learning were beneficial. In these experiments, individuals were “forced” with a probability of 5%, 15%, 25%, and 50% to match the resulting solution. Each run of the GA was replicated 10 times, with common random seeds. The genetic algorithm used in these experiments (described in [12]) runs in the Matlab computing environment, and was run using default parameters.A. Test ProblemsSeven different problems were used to ensure that (1) any effect observed held across different classes of problems as well as different instances of the problem and (2) was not due to some unknown structure of the specific class of problem selected, specific instance chosen, or the par-ticular LIP used.Corona Problems: The first problem set consists of three instances from a family of continuous, nonlinear, multi-modal functions developed by Corona et al. [5] to test the efficiency and effec-tiveness of simulated annealing as compared to stochastic hill-climbing and Nelder-Mead optimi-zation methods. This parametrized family of test functions is easy to compute and contains a large number of local minima. The function can be best described as an n-dimensional parabola with rectangular pockets removed with the global optima always occurring at the origin. These func-tions are parameterized with the number of dimensions (n), the number of local optima, and the width and height of the rectangular pockets. The same three problems (Cor2, Cor4, and Cor10) used in Corona et al. [5] and Houck et al. [12] were chosen for these experiments. A sequentialquadratic programming (SQP) optimization method was used as the LIP which is available in the Matlab environment.Location-Allocation Problem:The continuous location-allocation problem, a nonlinear, integer program as described in [11], will be used as the second problem set. The location-allocation problem (LA) is a type of multifacility location problem in which both the location of n new facil-ities and the allocation of the flow requirements of m exiting facilities to the new facilities are determined so that the total transportation costs are minimized. The location-allocation problem is a difficult optimization problem because its objective function is neither convex nor concave resulting in multiple local minima. Optimal solution techniques are limited to small problem instances (less than 25 existing facilities for general l p distances [16] and up to 35 for rectilinear distances [17]).The alternate location-allocation method developed by Cooper [4] will be used as the LIP for this problem. This method quickly finds a local minimum solution given a set of starting locations for the new facilities. This procedure works by starting with a set of new facility locations, it then determines an optimal set of allocations based on those locations. The optimal new facility loca-tions for these new allocations are then determined by solving n single facility location problems. This method continues until no further allocation changes are made. The individuals in the GA are a vector of real values representing the starting locations for the new facilities. T wo represen-tative problems (a 200 EFS by 20 new NFS and a 250 EFs by 25 new NFs) taken from [11] will be used in this experiment.Cell Formation Problem: The final problem set consists of two manufacturing cell-formation problems, non-linear integer programming problems described by [13]. The cell formation prob-lem is concerned with assigning a group of machines to a set of cells and a series of parts needing processing by these machines into families. The goal is to create a set of autonomous manufactur-ing units that eliminate inter-cell movements (i.e., a part needing processing by a machine outside its assigned cell). Consider an m machine and n part cell formation problem with k maximum cells, the problem is to assign each machine and part to one and only one cell or family, respec-tively. Joines et al. [13] developed an integer programming model with the following set variabledeclarations that eliminates the classical binary assignment variables and constraints.This representation has been shown to outperform other cell formation methods utilizing the same objective [13]. A greedy one-opt switching method as described in 14 will be used as the LIP Given an initial assignment of machines and parts to cells and families, respectively, the heuristic uses a set of improvement rules developed by Ng [20] to determine the improvement in the objec-tive function if machine i was switched from its current cell to any of the remaining k-1cells. The procedure repeats this step for each of the m machines as well for the parts and families. Two instances of the problem (King [15] and Chandrasekharan [2]) will be used as representative problems. The King data set is a 16x43 problem while the Chandrasekharan (Chan.) data set is a 100x40 problem.IV .R ESULTSThe results of these experiments were examined for effects in solution quality as well as computational efficiency. The results, in terms of solution quality, are provided in Table I. For comparison on the importance of using LIP with GAs, the table also shows the results when no local improvement (NLI) is used. For each problem instance, the first row provides the mean functional value found by the GA, the second row the mean of the number of generations it took the GA to find the best solution (not necessarily the optimal), and the third row is how many of the replications found the best known solution.Table I: Solution Qualityx i l ,=machine i is assigned to cell l y j l ,=part j is assigned to family lTable I: Solution QualityAs Table I shows, the use of a local improvement procedure improves the quality of the final solution found by the genetic algorithm. Also, the use of the Baldwin learning, 0%, does not perform as well as using some amount of Lamarckian learning. When some form of Lamarckian learning is employed, the genetic algorithm converges to the best known solution, except for 1 trial of both the 50% and 100% location-allocation problems.The results of these experiments with regard to computational efficiency are shown in Fig-ures 1-3. Each figure shows a box and whiskers plot of the generation the GA found the best solu-tion (not necessarily the optimal) for each problem instance. The boxes have lines at the lower quartile, median, and upper quartile values, and the whiskers show the range of the rest of the data. As can be seen, the genetic algorithm converges to the optimal solution much quicker when the genotypes are forced to match the phenotype through chromosome updating. In Figure 3(b), the logarithm of the number of generations until convergence is shown rather than the raw num-ber of generations until convergence. Without any forcing, this test problem takes a disproportion-ately larger number of generations to converge to the optimal. Each of these figures shows aFig. 1. Convergence on the Corana FunctionFig. 2. Convergence on the Location-Allocation ProblemFig. 3. Convergence for Cell Formation Problemscommon trend, with increasing levels of Lamarckian learning, the genetic algorithm convergesquicker, and as seen in Table I, the GA is converging to the best known solution.V.C ONCLUSIONSLocal improvement procedures were shown to enhance the performance of the genetic algorithm. Even though Lamarckian learning disrupts the schema processing of the genetic algorithm, it reduces the problem of a one-to-one genotype to phenotype mapping. Whereas, Baldwinian learn-ing does not affect the schema processing capabilities of the genetic algorithm, but results in a large number of genotypes mapping to the same phenotype.In the empirical investigation conducted, a general trend was observed where increasing use of Lamarckian learning led to the quicker convergence of the genetic algorithm to the best known solution for a series of test problems. By forcing the genotype to reflect the phenotype, the GA converges more quickly and to better solutions than by leaving the chromosome unchanged after evaluating it. This may seem counterintuitive since forcing the genotype to be equal to the pheno-type might have forced the GA to converge prematurely to one of these local optima. However, for this class of problems and procedures, Lamarckian learning outperformed Baldwinian learn-ing.R EFERENCES[1]H.Bersini and B.Renders. Hybridizing genetic algorithms with hill-climbing meth-ods for global optimization: Two possible ways. In1994 IEEE International Sympo-sium Evolutionary Computation, pages 312–317, Orlando, Fl, 1994.[2]M.Chandrasekharan and R.Rajagopalan. Zodiac-an algorithm for concurrent for-mation of part families and mac hine cells.International Journal of Production Re-search, 25(6):835–850, 1987.[3]P.Chu and J.Beasley. A genetic algorithm for the generalised assignment problem.Technical report, The Management School Imperial College London, 1995.[4]L.Cooper. The transportation-location problems.Operations Research, 20:94–108,1972.[5] A.Corana, M.Marchesi, C.Martini, and S.Ridella. Minimizing multimodal func-tions of continuous variables with the "simulated annealing" algorithm.ACM Trans-actions on Mathematical Software, 13(3):262–280, 1987.[6]L.Davis.Handbook of Genetic Algorithms. Van Nostrand Reinhold, New York,1991.[7] D.Goldberg.Genetic Algorithms in Search, Optimization & Machine Learning. Ad-11dison Wesley, Reading, MA, 1989.[8] F.Gruau and D.Whitley. Adding learning to the cellular development of neural net-works.Evolutionary Computation, 1:213–233, 1993.[9]G.Hinton and S.Nolan. How learning can guide plex Systems,1:495–502, 1987.[10] A.Homaifar, S.Guan, and G.E. Liepins. A new approach on the traveling salesmanproblem by genetic algorithms. In Proceedings of the 5th ICGA, pages 460–466,Champaign, IL, 1993.[11] C.R. Houck, J.A. Joines, and M.G. Kay. Comparison of genetic algorithms, ran-dom restart, and two-opt switching for solving large location-allocation problems.Computers and Operations Research, To Appear, 1996.[12] C.R. Houck, J.A. Joines, and M.G. Kay. A genetic algorithm for function optimi-zation: A Matlab implementation.ACM Transactions on Mathmatical Software,Submitted, 1996.[13]J.Joines, C.Culbreth, and R.King. Manufacturing cell design: An integer program-ming model employing genetic.IIE Transactions, 28(1), 1996.[14]J.Joines, R.King, and C.Culbreth. The use of a local improvement heuristic with agenetic algorithm for manufacturing cell design. Technical Report NCSU-IE Tech-nical Report 95-06, North Carolina State University, 1995.[15]J.King. Machine-component grouping formation in group technology.InternationalJournal of Management Science, 8(2):193–199, 1980.[16]R.Love and H.Juel. Properties and solution methods for large location-allocationproblems with rectangular distances.Journal Operations Research Society, 33:443–452, 1982.[17]R.Love and J.Morris. A computational procdure for the exact solution of location-allocation problems with rectangular distances.Naval Research Logistics Quartly,22:441–453, 1975.[18]Z.Michalewicz.Genetic Algorithms + Data Structures = Evolutionary Programs.Springer-Verlang, New York, 2nd edition, 1994.[19]R.Nakano. Conventional genetic algorithm for job shop problems. In Proc. of the 4thICGA, pages 474–479, San Mateo, CA, 1991.[20]S.Ng. Worst-case analysis of an algorithm for cellular manufacturing.EuropeanJournal of Operational Research, 69(3):384–398, 1993.[21] D.Whitley. A genetic algorithm tutorial.Statics and Computing, 4:65–85, 1994.[22] D.Whitley, S.Gordon, and K.Mathias. Larmarckian evolution, the Baldwin effectand function opimization. In Y.Davidor, H.Schwefel, and R.Manner, editors,Par-allel Problem Solving from Nature-PPSN III, pages 6–15. Springer-Verlag, 1994.。

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