A-317491 sodium salt hydrate__DataSheet_MedChemExpress
QIAGEN Endotoxin Removal Solution说明书

Endotoxin Removal Solution Catalog Number E4274Product DescriptionEndotoxins are lipopolysaccharides (LPS), a major component of the Gram-negative bacterial cell wall, and are commonly found as contaminants in plasmid DNA preparations from E. coli. Endotoxins are large, negatively charged molecules that co-purify with DNA on ion exchange and size exclusion columns and in CsCl banding. Endotoxins are extremely potent stimulators of the mammalian immune system and are toxic to primary cells and to animals. The endotoxin toxicity is an obstacle to in vitro and in vivo transfection experiments.Non-ionic detergents, traditionally used for separation of integral membrane proteins,1 can be utilized for removal of endotoxins from DNA solutions by phase separation.2The solubility behavior of a detergent in a dilute, aqueous solution at physiological salt and pH conditions is strongly dependent upon the temperature of the solution. At low temperatures, the detergent forms a clear, micellar solution, but above the cloud point temperature, the micelles form larger, turbid aggregates and ultimately fuse to form a separate phase. The lower phase is detergent-enriched and the detergent-depleted upper phase contains detergent at a concentration slightly above the critical micellar concentration (CMC). Amphiphilic and hydrophobic molecules associated with the micelles of the detergent will aggregate within the detergent-enriched phase, while the soluble, hydrophilic molecules will remain in the detergent-depleted upper phase.Extraction of endotoxin contaminated DNA solutions with the appropriate non-ionic detergent will separate the hydrophilic DNA from the amphiphilic endotoxin. The amphiphilic endotoxin will associate with the lower phase, while the DNA will remain in the upper, detergent-depleted phase.2Reagents and equipment required, but not provided • Water, Molecular Biology Reagent, Catalog Number W4502• E-TOXATE® Water, Catalog Number 2107, or Tris-EDTA (TE) buffer 100×, Catalog NumberT9285• DNA solution (0.5 ml), ~ 1 mg/ml in E-TOXATE®Water or TE buffer• 3 M sodium acetate solution, pH 7.5.• 2-Propanol, Catalog Number I9516, or Ethanol, 190 proof, Catalog Number E7148; 200 proof, CatalogNumber E7023• 70% Ethanol• E-TOXATE®reagents Kits, Catalog Numbers 210A1, 210B1 or 210C1• Ice bucket• Heat block or incubator at 37 °C• Microcentrifuge at room temperature• 1.5 or 2 ml sterile microcentrifuge tubes• Endotoxin-free pipet tips (40-200 µl, 200-1000 µl) Precautions and DisclaimerThis product is for R&D use only, not for drug, household, or other uses. Please consult the Material Safety Data Sheet for information regarding hazards and safe handling practices.StorageStore at room temperature.Note: Removal of endotoxins from DNA preparations can be performed either during the final stage of DNApreparation, or during an earlier stage.Procedures for Endotoxin RemovalDuring the final stage of DNA preparationNote: The procedure described below was performed on plasmid DNA produced in E. coli DH5α cells.• Losses of up to 50% of the DNA are expected. • Use of a DNA concentration above therecommended 1 mg/ml reduces the efficiency ofthe procedure.1. Pipette 500 µl of the DNA solution into a sterilemicrocentrifuge tube.2. Add 50 µl of the 3 M sodium acetate solution to theDNA sample.3. Incubate on ice for 5 minutes.4. Add 100 µl of cold Endotoxin Removal Solution.5. Mix thoroughly and incubate on ice for 10 minutes.The solution should be light blue and clear.6. Incubate the tube at 37 °C for 20 to 30 minutes oruntil the phases separate.7. Spin for 5 minutes at 3000 x g in themicrocentrifuge. The upper phase is colorless and clear, while the lower phase is blue.8. Carefully transfer the upper phase containing theDNA to a clean microcentrifuge tube.9. Repeat steps 4 through 8 twice.10. Add 0.6× volume of 2-propanol. Mix by inversion atroom temperature and centrifuge at 15,000 x g for30 minutes at 4 °C. Alternatively, add2.5× volumes of ethanol. Incubate overnight at –20°C or 20 minutes at –70 °C and centrifuge at15,000 x g for 30 minutes at 4 °C.11. Carefully remove the supernatant12. Wash the DNA pellet twice with cold 70% ethanol.Remove the supernatant.13. Air-dry the pellet.14. Suspend the DNA in 100 µl of endotoxin free wateror TE buffer.15. Determine DNA concentration and endotoxin levelsusing endotoxin assay reagents and compare tothe starting material. During an earlier stage of DNA preparationThis procedure is based on the alkaline lysis of E. coli DH5α cells.3 The endotoxins are removed immediately after alkaline cell lysis, neutralization, and a clarification step. The resulting high salt solution is suitable for the endotoxin removal step. It is performed under “endotoxin free” conditions. The plasticware used is either sterile and disposable, or NaOH-treated. The buffers are prepared with endotoxin free water.1. Add the Endotoxin Removal Solution (0.2× volume)to the cold, crude DNA solution.2. Incubate on ice and mix occasionally by inversionto obtain a homogenous, clear blue solution3. Incubate at 37 °C for 20 to 30 minutes until thephase separation is obvious.4. Spin for 5 minutes at low speed (3000 x g) at roomtemperature.5. Transfer the upper aqueous phase to an endotoxinfree container.6. Proceed with the DNA purification by any method.Use endotoxin-free buffers and containers. References1. Bordier, C., J. Biol. Chem., 256, 1604-1607, (1981).2. Cotten, M. et al., Gene Therapy, 1, 239-246,(1994).3. Sambrook et al., Molecular Cloning, a LaboratoryManual, 2nd Ed. p. 1.38RK,PHC 09/05-1Sigma brand products are sold through Sigma-Aldrich, Inc.Sigma-Aldrich, Inc. warrants that its products conform to the information contained in this and other Sigma-Aldrich publications. Purchaser must determine the suitability of the product(s) for their particular use. Additional terms and conditions may apply. Please see reverse side ofthe invoice or packing slip.。
HANKS' BALANCED SALTS [HBSS] 产品说明书
![HANKS' BALANCED SALTS [HBSS] 产品说明书](https://img.taocdn.com/s3/m/181984b63086bceb19e8b8f67c1cfad6185fe96d.png)
HANKS' BALANCED SALTS [HBSS]Without calcium chloride, magnesium sulfate and sodium bicarbonate Product Number H2387Product DescriptionAlthough there have been many modifications to the original formulas in efforts to produce fully defined media, salt solutions still play an important role in tissue culture. A salt solution's basic function, to maintain the pH and osmotic balance in the medium and to provide the cells with water and essentialinorganic ions, is as valuable today as when it was first developed a century ago.Componentsg/L Potassium Chloride0.4Potassium Phosphate Monobasic 0.06(anhydrous)Sodium Chloride8.0Sodium Phosphate Dibasic(anhydrous)0.04788D -Glucose1.0Phenol Red•Na0.011Precautions and Disclaimer REAGENTFor R&D use only. Not for drug, household or other uses.Preparation InstructionsPowdered salts are hygroscopic and should beprotected from moisture. The entire contents of each package should be used immediately after opening. Preparing a concentrated salt solution is notrecommended as precipitates may form. Supplements can be added prior to filtration or introduced aseptically to sterile salt solution.1.Measure out 90% of final required volume ofwater. Water temperature should be 15-20 ˚C.2.While gently stirring the water, add the powderedmedium. Stir until dissolved. Do NOT heat. 3.Rinse original package with a small amount ofwater to remove all traces of powder. Add to solution in step 2.4.To the solution in step 3, add 0.35 g sodiumbicarbonate or 4.7 ml of sodium bicarbonatesolution [7.5%w/v] for each liter of final volume of medium being prepared. Stir until dissolved.5.While stirring, adjust the pH of the medium to 0.1-0.3 pH units below the desired pH since it may rise during filtration. The use of 1N HCl or 1N NaOH is recommended.6.Add additional water to bring the solution to finalvolume.7.Sterilize immediately by filtration using amembrane with a porosity of 0.22 microns.8.Aseptically dispense medium into sterile container. Storage and StabilityStore the dry powdered salts at 2-8 °C under dry conditions and liquid medium at 2-8 °C in the dark. Deterioration of the powdered medium may be recognized by any or all of the following: [1] color change, [2] granulation/clumping, [3] insolubility.Deterioration of the liquid medium may be recognized by any or all of the following: [1] pH change, [2] precipitate or particulates, [3] cloudy appearance [4] color change. The nature of supplements added may affect storage conditions and shelf life of the medium. Product label bears expiration date.ProcedureMaterials Required but Not Provided:Water for tissue culture [W3500]Sodium Bicarbonate [S5761] orSodium Bicarbonate Solution, 7.5% [S8761]1N Hydrochloric Acid [H9892]1N Sodium Hydroxide [S2770]Medium additives as requiredReference1.Hanks, J. (1976) Hanks' Balanced SaltSolution and pH Control. Tissue Culture Association Manual. 3, 3.Revised: March 2007Sigma-Aldrich, I nc. warrants that its products conform to the information contained in this and other Sigma-Aldrich publications. Purchaser must determine the suitability of the product(s) for their particular use. Additional terms and conditions may apply. Please see reverse side of the invoice or packing slip.。
Inosine-5'-monophosphate (sodium salt hydrate)_IMP脱氢酶(IMPDH)的底物_20813-76-7_Apexbio

Inosine-5'-monophosphate is a substrate of IMP dehydrogenase. Inosine-5'-monophosphate dehydrogenase (IMPDH) is an enzyme responsible to the biosynthesis of guanine nucleotides. IMPDH inhibitors have been approved for prevention of organ transplant rejection.
Soluble in DMSO
Store at -20°C
For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.
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产品仅用于研究,
不针对患者销售,望谅解。
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产品说明书
化学性质
产品名: Inosine-5'-monophosphate (sodium salt hydrate).: 分子量: 分子式: 别名: 化学名: SMILES:
溶解性: 储存条件: 一般建议:
洋甘菊提取液MSDS英文版

1. IDENTIFICATION OF THE SUBSTANCE/TREPARATION AND THE COMPANY/UNDERTAKING3.HAZARDS IDENTIFICATION4. FIRST AID MEASURESMATERIAL SAFETY DATA SHEETProduct name:Supplier:Tel:EMERGENCY OVERVIEW: May cause skin irritation and/or dermatitisPrinciple routes of exposure: Inhalation: Ingestion: Skin contact: Eye contact:SkinMay cause irritation of respiratory tract May be harmful if swallowed May cause allergic skin reaction Avoid contact with eyesStatements of hazard MAY CAUSE ALLERGIC SKIN REACTION.Statements of Spill of Leak Label Eliminate all ignition sources. Absorb and/or contain spill with inert materials (e.g., sand, vermiculite). Then place in appropriate container. For large spills, use water spray to disperse vapors, flush spill area. Prevent runoff from entering waterways or sewers.General advice:POSITION/INFORMATION ON INGREDIENTSInhalation:Skin contact:Ingestion:Eye contact:Protection of first – aiders:Medical conditions aggravated by exposure: In the case of accident or if you fell unwell, seek medical advice immediately (show the label where possible).Move to fresh air, call a physician immediately.Rinse immediately with plenty of water and seek medical adviceDo not induce vomiting without medical advice.In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.No information availableNone knownSuitable extinguishing media:Specific hazards:Special protective equipment for firefighters:Flash point:Autoignition temperature:NFPA rating Use dry chemical, CO2, water spray or “alcohol” foam Burning produces irritant fumes.As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gearNot determinedNot determinedNFPA Health: 1 NFPA Flammability: 1 NFPA Reactivity: 0Personal precautions: Environmental precautions: Methods for cleaning up: Use personal protective equipment.Prevent product from entering drains.Sweep up and shovel into suitable containers for disposalStorage:7. HANDLING AND STORAGE5.FIRE-FIGHTING MEASURES6. ACCIDENTAL RELEASE MEASURESRoom temperature Handling:Safe handling advice: Incompatible products:Use only in area provided with appropriate exhaust ventilation.Wear personal protective equipment.Oxidising and spontaneously flammable productsEngineering measures: Respiratory protection: Skin and body protection:Eye protection: Hand protection: Hygiene measures:Ensure adequate ventilation.Breathing apparatus only if aerosol or dust is formed. Usual safety precautions while handling the product will provide adequate protection against this potential effect. Safety glasses with side-shieldsPVC or other plastic material glovesHandle in accordance with good industrial hygiene and safety practice.Melting point/range: Boiling point/range: Density: Vapor pressure: Evaporation rate: Vapor density: Solubility (in water): Flash point:Autoignition temperature:No Data available at this time. No Data available at this time. No data available No data available No data available No data available No data available Not determined Not determinedStability: Stable under recommended storage conditions. Polymerization: None under normal processing.Hazardous decomposition products: Thermal decomposition can lead to release of irritating gases and vapours such as carbon oxides.Materials to avoid: Strong oxidising agents.10. STABILITY AND REACTIVITY9. PHYSICAL AND CHEMICAL PROPERTIES8. EXPOSURE CONTROLS/PERSONAL PROTECTION11. TOXICOLOGICAL INFORMATIONConditions to avoid: Exposure to air or moisture over prolonged periods.Product information Acute toxicityChronic toxicity:Local effects: Chronic exposure may cause nausea and vomiting, higher exposure causes unconsciousness.Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting.Specific effects:May include moderate to severe erythema (redness) and moderate edema (raised skin), nausea, vomiting,headache.Primary irritation: Carcingenic effects: Mutagenic effects: Reproductive toxicity:No data is available on the product itself. No data is available on the product itself. No data is available on the product itself. No data is available on the product itself.Mobility:Bioaccumulation: Ecotoxicity effects: Aquatic toxicity:No data available No data available No data availableMay cause long-term adverse effects in the aquatic environment.12. ECOLOGICAL INFORMATION13. DISPOSAL CONSIDERATIONSWaste from residues/unused products:Contaminated packaging:Waste disposal must be in accordance with appropriate Federal, State and local regulations. This product, if unaltered by use, may be disposed of treatment at a permitted facility or as advised by your local hazardous waste regulatory authority. Residue from fires extinguished with this material may be hazardous.Do not re-use empty containers.UN/Id No:Not regulated14. TRANSPORT INFFORMATIONDOTProper shipping name: Not regulatedTGD(Canada)WHMIS hazard class: Non - controlledIMDG/IMOIMDG – Hazard Classifications Not ApplicableIMO – labels:15. REGULATORY INFOTMATION International Inventories16. OTHER INFORMATIONPrepared by: Health & SafetyDisclaimer: The information and recommendations contained herein are based upon tests believed to be reliable.However, XABC does not guarantee the accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY, WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOOD, THE MERCHANTABILITY OF THE GOODS, OR THE FITNESS OF THE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage maybe required. XABC assumes no responsibility for results obtained or for incidental or consequential damages, including lost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made or implied.End of safety data sheet。
水溶液臭味除妥氧化物灌洗用品安全数据表说明书

SAFETY DATA SHEET 1. IdentificationProduct identifier: Water Based Malodor Air Freshener & DeodorizerOther means of identificationSDS number: RE1000037011Recommended restrictionsProduct Use: Air FreshenerRestrictions on use:Not known.Manufacturer/Importer/Distributor InformationManufacturerCompany Name: CLAIRE MANUFACTURING COMPANYAddress: 1000 Integram DrPacific, MO 63069Telephone: 1-630-543-7600Fax:Emergency telephone number: 1-866-836-88552. Hazard(s) identificationHazard ClassificationPhysical HazardsFlammable aerosol Category 1Label ElementsHazard Symbol:Signal Word:DangerHazard Statement: Extremely flammable aerosol.PrecautionaryStatementssources. No smoking. Do not spray on an open flame or other ignitionsource. Do not pierce or burn, even after use.Storage: Protect from sunlight. Do not expose to temperatures exceeding50°C/122°F.Hazard(s) not otherwiseNone.classified (HNOC):3. Composition/information on ingredientsMixturesChemical Identity CAS number Content in percent (%)*2-Propanol67-63-0 1 - <5%Nitrogen7727-37-9 0 - <0.1%4. First-aid measuresIngestion:Rinse mouth thoroughly.Inhalation: Move to fresh air.Skin Contact:Remove contaminated clothing and wash the skin thoroughly with soap andwater after work.Eye contact:Rinse immediately with plenty of water.Most important symptoms/effects, acute and delayedSymptoms: No data available.Hazards: No data available.Indication of immediate medical attention and special treatment neededTreatment:No data available.5. Fire-fighting measuresGeneral Fire Hazards: Use water spray to keep fire-exposed containers cool. Fight fire from aprotected location. Move containers from fire area if you can do so withoutrisk.Suitable (and unsuitable) extinguishing mediaSuitable extinguishingmedia:Use fire-extinguishing media appropriate for surrounding materials.Unsuitable extinguishingmedia:Do not use water jet as an extinguisher, as this will spread the fire.Specific hazards arising from the chemical:Vapors may travel considerable distance to a source of ignition and flash back.Special protective equipment and precautions for firefighters Special fire fightingprocedures:No data available.Special protective equipment for fire-fighters: Firefighters must use standard protective equipment including flame retardant coat, helmet with face shield, gloves, rubber boots, and in enclosed spaces, SCBA.6. Accidental release measuresPersonal precautions,protective equipment and emergency procedures: Ventilate closed spaces before entering them. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Keep upwind.Methods and material for containment and cleaning up: Stop the flow of material, if this is without risk. Absorb with sand or other inert absorbent.Notification Procedures:ELIMINATE all ignition sources (no smoking, flares, sparks or flames inimmediate area). Stop leak if you can do so without risk.Environmental Precautions: Avoid release to the environment. Prevent further leakage or spillage if safeto do so. Do not contaminate water sources or sewer. Environmentalmanager must be informed of all major spillages.7. Handling and storagePrecautions for safe handling: Keep away from heat, hot surfaces, sparks, open flames and other ignitionsources. No smoking. Do not spray on an open flame or other ignitionsource. Do not pierce or burn, even after use. Do not handle until all safetyprecautions have been read and understood. Obtain special instructionsbefore use. Use personal protective equipment as required.Conditions for safe storage, including anyincompatibilities: Pressurized container: protect from sunlight and do not expose to temperatures exceeding 50°C. Do not pierce or burn, even after use. Store locked up. Aerosol Level 18. Exposure controls/personal protectionOccupational Exposure LimitsChemical Identity Type Exposure Limit Values Source2-Propanol REL400 ppm980 mg/m3US. NIOSH: Pocket Guide to ChemicalHazards(2005)STEL400 ppm US. ACGIH Threshold Limit Values(2008)STEL500 ppm1,225 mg/m3US. OSHA Table Z-1-A (29 CFR 1910.1000)(1989)STEL500 ppm1,225 mg/m3US. Tennessee. OELs. Occupational ExposureLimits, Table Z1A(06 2008)TWA400 ppm980 mg/m3US. Tennessee. OELs. Occupational ExposureLimits, Table Z1A(06 2008)PEL400 ppm980 mg/m3US. OSHA Table Z-1 Limits for AirContaminants (29 CFR 1910.1000)(02 2006)TWA400 ppm980 mg/m3US. OSHA Table Z-1-A (29 CFR 1910.1000)(1989)STEL500 ppm1,225 mg/m3US. California Code of Regulations, Title 8,Section 5155. Airborne Contaminants(092006)AN ESL200 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)ST ESL2,000 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)STEL500 ppm1,225 mg/m3US. NIOSH: Pocket Guide to ChemicalHazards(2005)TWA200 ppm US. ACGIH Threshold Limit Values(2008)TWA PEL400 ppm980 mg/m3US. California Code of Regulations, Title 8,Section 5155. Airborne Contaminants(092006)AN ESL492 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)ST ESL4,920 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)1,2-Benzenedicarboxylic acid, 1,2-diethyl ester REL 5 mg/m3US. NIOSH: Pocket Guide to ChemicalHazards(2005)TWA 5 mg/m3US. ACGIH Threshold Limit Values(2008) TWA PEL 5 mg/m3US. California Code of Regulations, Title 8,Section 5155. Airborne Contaminants(092006)TWA 5 mg/m3US. OSHA Table Z-1-A (29 CFR 1910.1000)(1989)TWA 5 mg/m3US. Tennessee. OELs. Occupational ExposureLimits, Table Z1A(06 2008)ST ESL50 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL 5 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)Acetic acid, pentyl ester REL100 ppm525 mg/m3US. NIOSH: Pocket Guide to ChemicalHazards(2005)TWA50 ppm US. ACGIH Threshold Limit Values(2008)STEL100 ppm US. ACGIH Threshold Limit Values(2008)STEL100 ppm532 mg/m3US. California Code of Regulations, Title 8,Section 5155. Airborne Contaminants(092006)TWA PEL50 ppm266 mg/m3US. California Code of Regulations, Title 8,Section 5155. Airborne Contaminants(092006)TWA100 ppm525 mg/m3US. Tennessee. OELs. Occupational ExposureST ESL2,700 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)ST ESL500 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL50 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL270 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)PEL100 ppm525 mg/m3US. OSHA Table Z-1 Limits for AirContaminants (29 CFR 1910.1000)(02 2006)TWA100 ppm525 mg/m3US. OSHA Table Z-1-A (29 CFR 1910.1000)(1989)TWA20 ppm US. ACGIH Threshold Limit Values(2008) Bicyclo[3.1.1]hept-2-ene,2,6,6-trimethyl-ST ESL3,500 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)ST ESL630 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL63 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL350 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)TWA10 ppm US. ACGIH Threshold Limit Values(2008) Acetic acid, phenylmethylesterTWA PEL10 ppm61 mg/m3US. California Code of Regulations, Title 8,Section 5155. Airborne Contaminants(092006)ST ESL100 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL10 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)ST ESL610 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL61 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)STEL 2 ppm US. ACGIH Threshold Limit Values(03 2018) Benzene, 1,1'-oxybis- -Vapor.TWA 1 ppm US. ACGIH Threshold Limit Values(03 2018)PEL 1 ppm7 mg/m3US. OSHA Table Z-1 Limits for AirContaminants (29 CFR 1910.1000)(02 2006)TWA PEL 1 ppm7 mg/m3US. California Code of Regulations, Title 8,Section 5155. Airborne Contaminants(092006)REL 1 ppm7 mg/m3US. NIOSH: Pocket Guide to ChemicalHazards(2005)TWA 1 ppm7 mg/m3US. OSHA Table Z-1-A (29 CFR 1910.1000)(1989)Benzene, 1,1'-oxybis-ST ESL70 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL7 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)Benzene, 1,1'-oxybis- - TWA 1 ppm7 mg/m3US. Tennessee. OELs. Occupational ExposureBenzene, 1,1'-oxybis-ST ESL10 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL 1 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)TWA 5 ppm US. ACGIH Threshold Limit Values(01 2010) 2,6-Octadienal, 3,7-dimethyl-- Inhalable fraction andvapor.2,6-Octadienal, 3,7-dimethyl-ST ESL50 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)ST ESL310 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL31 µg/m3 US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)AN ESL 5 ppb US. Texas. Effects Screening Levels (TexasCommission on Environmental Quality)(112016)Biological Limit ValuesChemical Identity Exposure Limit Values Source40 mg/l (Urine)ACGIH BEL (03 2013)2-Propanol (acetone:Sampling time: End of shift atend of work week.)Appropriate EngineeringNo data available.ControlsIndividual protection measures, such as personal protective equipmentGeneral information:Use personal protective equipment as required. Personal protectionequipment should be chosen according to the CEN standards and indiscussion with the supplier of the personal protective equipment.Eye/face protection: Wear goggles/face shield.Skin ProtectionHand Protection:No data available.Other: No data available.Respiratory Protection:In case of inadequate ventilation use suitable respirator. Seek advice fromlocal supervisor.Hygiene measures:When using do not smoke. Observe good industrial hygiene practices. Donot handle until all safety precautions have been read and understood.Obtain special instructions before use.9. Physical and chemical propertiesAppearancePhysical state:liquidForm: Spray AerosolOdor: No data available.Odor threshold: No data available.pH: No data available.Melting point/freezing point: No data available.Initial boiling point and boiling range: Estimated 100 °CFlash Point: Estimated 12.2 °CEvaporation rate: No data available.Flammability (solid, gas): No data available.Upper/lower limit on flammability or explosive limitsFlammability limit - upper (%): No data available.Flammability limit - lower (%):No data available.Explosive limit - upper (%):No data available.Explosive limit - lower (%):No data available.Vapor pressure:7,584.233 - 8,963.1845 hPa (20 °C)Vapor density:No data available.Density: No data available.Relative density:No data available.Solubility(ies)Solubility in water:No data available.Solubility (other):No data available.Partition coefficient (n-octanol/water):No data available.Auto-ignition temperature:No data available.Decomposition temperature:No data available.Viscosity:No data available.10. Stability and reactivityReactivity: No data available.Chemical Stability: Material is stable under normal conditions. Possibility of hazardousNo data available.reactions:Conditions to avoid: Avoid heat or contamination.Incompatible Materials: No data available.Hazardous DecompositionNo data available.Products:11. Toxicological informationInformation on likely routes of exposureSkin Contact: No data available.Eye contact: No data available.Ingestion: No data available.Symptoms related to the physical, chemical and toxicological characteristics Inhalation: No data available.Skin Contact: No data available.Eye contact: No data available.Ingestion: No data available.Information on toxicological effectsAcute toxicity (list all possible routes of exposure)OralProduct: Not classified for acute toxicity based on available data.Specified substance(s):2-Propanol LD 50 (Rat):5.84 g/kgDermalProduct: Not classified for acute toxicity based on available data.Specified substance(s):2-Propanol LD 50:> 2,000 mg/kgInhalationProduct: Not classified for acute toxicity based on available data.Specified substance(s):2-Propanol LC 50:> 5 mg/lLC 50:> 20 mg/lRepeated dose toxicityProduct: No data available.Specified substance(s):2-Propanol NOAEL (Rat, Inhalation, >= 104 Weeks): 5,000 ppm(m) InhalationExperimental result, Key studySkin Corrosion/IrritationProduct: No data available.Specified substance(s):2-Propanol in vivo (Rabbit): Not Classified Experimental result, Key study Serious Eye Damage/Eye IrritationProduct: No data available.Specified substance(s):2-Propanol Rabbit, 1 d: Irritating.Respiratory or Skin SensitizationProduct: No data available.Specified substance(s):2-Propanol Skin sensitization:, in vivo (Guinea pig): Non sensitising CarcinogenicityProduct: No data available.IARC Monographs on the Evaluation of Carcinogenic Risks to Humans:No carcinogenic components identifiedUS. National Toxicology Program (NTP) Report on Carcinogens:No carcinogenic components identifiedUS. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050):No carcinogenic components identifiedGerm Cell MutagenicityIn vitroProduct: No data available.In vivoProduct: No data available.Reproductive toxicityProduct: No data available.Specific Target Organ Toxicity - Single ExposureProduct: No data available.Specific Target Organ Toxicity - Repeated ExposureProduct: No data available.Aspiration HazardProduct: No data available.Other effects: No data available.12. Ecological informationEcotoxicity:Acute hazards to the aquatic environment:FishProduct: No data available.Specified substance(s):2-Propanol LC 50 (Pimephales promelas, 96 h): 9,640 mg/l Experimental result, KeystudyAquatic InvertebratesProduct: No data available.Specified substance(s):2-Propanol LC 50 (Daphnia magna, 24 h): > 10,000 mg/l Experimental result, Key study Chronic hazards to the aquatic environment:FishProduct: No data available.Aquatic InvertebratesProduct: No data available.Toxicity to Aquatic PlantsProduct: No data available.Persistence and DegradabilityBiodegradationProduct: No data available.Specified substance(s):2-Propanol53 % (5 d) Detected in water. Experimental result, Key study BOD/COD RatioProduct: No data available.Bioaccumulative potentialBioconcentration Factor (BCF)Product: No data available.Partition Coefficient n-octanol / water (log Kow)Product: No data available.Mobility in soil: No data available.Known or predicted distribution to environmental compartments2-Propanol No data available.Nitrogen No data available.Other adverse effects: No data available.13. Disposal considerationsDisposal instructions: Discharge, treatment, or disposal may be subject to national, state, or locallaws.Contaminated Packaging: No data available.14. Transport informationDOTUN Number: UN 1950UN Proper Shipping Name: Aerosols, flammableTransport Hazard Class(es)Class: 2.1Label(s): –Packing Group: IIMarine Pollutant: NoEnvironmental Hazards: NoMarine Pollutant NoSpecial precautions for user: Not regulated.IMDGUN Number: UN 1950UN Proper Shipping Name: Aerosols, flammableTransport Hazard Class(es)Class: 2Label(s): –EmS No.:Packing Group: –Environmental Hazards: NoMarine Pollutant NoSpecial precautions for user: Not regulated.IATAUN Number: UN 1950Proper Shipping Name: Aerosols, flammableTransport Hazard Class(es):Class: 2.1Label(s): –Packing Group: –Environmental Hazards: NoMarine Pollutant NoSpecial precautions for user: Not regulated.15. Regulatory informationUS Federal RegulationsTSCA Section 12(b) Export Notification (40 CFR 707, Subpt. D)US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050) None present or none present in regulated quantities.CERCLA Hazardous Substance List (40 CFR 302.4):Chemical Identity Reportable quantity2-Propanol lbs. 100lbs. 10001,2-Benzenedicarboxylicacid, 1,2-diethyl esterAcetic acid, pentyl ester lbs. 5000lbs. 100Bicyclo[3.1.1]hept-2-ene,2,6,6-trimethyl-Superfund Amendments and Reauthorization Act of 1986 (SARA) Hazard categoriesFire HazardFlammable aerosolSARA 302 Extremely Hazardous SubstanceNone present or none present in regulated quantities.SARA 304 Emergency Release NotificationChemical Identity Reportable quantity2-Propanol lbs. 100lbs. 10001,2-Benzenedicarboxylicacid, 1,2-diethyl esterAcetic acid, pentyl ester lbs. 5000lbs. 100Bicyclo[3.1.1]hept-2-ene,2,6,6-trimethyl-SARA 311/312 Hazardous ChemicalChemical Identity Threshold Planning Quantity 2-Propanol10000lbs1,2-Benzenedicarboxylicacid, 1,2-diethyl ester10000lbsAcetic acid, pentyl ester10000lbsBicyclo[3.1.1]hept-2-ene,2,6,6-trimethyl-10000lbsAcetic acid, phenylmethylester10000lbsBenzene, 1,1'-oxybis-10000lbs2,6-Octadienal, 3,7-dimethyl-10000lbsNitrogen10000lbsSARA 313 (TRI Reporting)Chemical Identity Reportingthreshold forother usersReporting threshold formanufacturing andprocessing2-Propanol lbs lbs.Clean Air Act (CAA) Section 112(r) Accidental Release Prevention (40 CFR 68.130):Clean Water Act Section 311 Hazardous Substances (40 CFR 117.3)US State RegulationsUS. California Proposition 65This product contains chemical(s) known to the State of California to cause cancer and/or to cause birth defects or other reproductive harm.Methanone, diphenyl-Carcinogenic. 07 2012US. New Jersey Worker and Community Right-to-Know ActChemical Identity2-PropanolUS. Massachusetts RTK - Substance ListNo ingredient regulated by MA Right-to-Know Law present.US. Pennsylvania RTK - Hazardous SubstancesChemical Identity2-PropanolUS. Rhode Island RTKNo ingredient regulated by RI Right-to-Know Law present.International regulationsMontreal protocolNot applicableStockholm conventionNot applicableRotterdam conventionNot applicableKyoto protocolNot applicableInventory Status:Australia AICS: Not in compliance with the inventory.EINECS, ELINCS or NLP: Not in compliance with the inventory.Japan (ENCS) List: Not in compliance with the inventory.China Inv. Existing Chemical Substances: Not in compliance with the inventory.Korea Existing Chemicals Inv. (KECI): Not in compliance with the inventory.Canada NDSL Inventory: Not in compliance with the inventory.Philippines PICCS: Not in compliance with the inventory.New Zealand Inventory of Chemicals: Not in compliance with the inventory.Japan ISHL Listing: Not in compliance with the inventory.Japan Pharmacopoeia Listing: Not in compliance with the inventory.Mexico INSQ: Not in compliance with the inventory.Ontario Inventory: Not in compliance with the inventory.Taiwan Chemical Substance Inventory: Not in compliance with the inventory.Canada DSL Inventory List: On or in compliance with the inventory US TSCA Inventory: On or in compliance with the inventory 16.Other information, including date of preparation or last revisionIssue Date: 07/31/2019Revision Information:No data available.Version #: 1.0Further Information: No data available.Disclaimer: This information is provided without warranty. The information is believed tobe correct. This information should be used to make an independentdetermination of the methods to safeguard workers and the environment.。
生物纯度氨酸钠二氧化钙(氯酸氯酸钠)说明书

71188 Sodium acetate trihydrate (Acetic acid sodium salt)CAS number: 6131-90-4Product Description:Appearance: Clear colorless to very faint yellow liquidMolecular formula: CH3COONa • 3 H2OFormula weight: 136.08 g/molSolubility: 3 M in H2O, 20°C, complete, colorlesspH: 8.5-10.0 (3 M in H2O, 25°C)This product designated as BioUltra grade is suitable for different applications like purification, precipitation, crystallisation and other applications which require tight control of elemental content. Trace elemental analyses have been performed. The Certificate of Analysis provides lot-specific results.Applications:Sodium acetate is a widely used reagent in molecular biology applications. It is used as a buffer in conjunction with acetic acid, in the buffering range of pH 3.6 - 5.6. Sodium acetate is used in the purification and precipitation of nucleic acids,1,2,3 protein crystallization,4 staining of gels in protein gel electrophoresis,5 and HPLC.6 Large scale applications of sodium acetate include its use as a retardantin plastics manufacturing, as a mordant in dyeing, and in the tanning of leather.7 A DNA microarray study of E. coli response to different levels of sodium acetate has been reported.8 Protein unfolding during reversed phase chromatography in the presence of varying salts, including sodium acetate, at different ionic strengths has been investigated.9 Sodium acetate has been used in conjunction with sodium carbonate to enhance the activation of freeze-dried subtilisin Carlsberg in organic solvents.10 Sodium acetate may be used as a substrate for acetokinase (acetate kinase; EC 2.7.2.1).11Preparation InstructionsSodium acetate is soluble in water (3 mol/l), yielding a clear, colorless solution. The pH of a 0.1 M aqueous sodium acetate solution at 25°C is 8.9.8References:1.Evans, J. K., et al., Simultaneous purification of RNA and DNA from liver using sodium acetateprecipitation. BioTechniques, 24, 416-418 (1998).2.Molecular Cloning: A Laboratory Manual, 3rd ed., Sambrook, J. F., et al., Cold Spring HarborLaboratory Press (Cold Spring Harbor, NY: 2001), pp. 6.26-6.27, A8.12-A8.16.3.Wallace, D. M., Large- and Small-Scale Phenol Extractions, Meth. Enzymol., 152, 33-41 (1987).4.Baniecki, M. L., et al., Adenovirus proteinase: crystallization and preliminary X-ray diffractionstudies to atomic resolution. Acta Crystallogr. D Biol. Crystallogr., 58 (Pt 9), 1462-1464 (2002).5.Bjellqvist, B., et al., A nonlinear wide-range immobilized pH gradient for two-dimensionalelectrophoresis and its definition in a relevant pH scale. Electrophoresis, 14, 1357-1365 (1993).6.Clark, T. N., et al., Determination of 3'-azido-2',3'-dideoxyuridine in maternal plasma, amnioticfluid, fetal and placental tissues by high-performance liquid chromatography. J. Chromatogr. B Biomed. Sci. Appl., 755(1-2), 165-172 (2001).7.The Merck Index, 12th ed., Entry# 8711.8.Polen, T., et al., DNA microarray analyses of the long-term adaptive response of Escherichia colito acetate and propionate. Appl. Environ. Microbiol., 69(3), 1759-1774 (2003).The vibrant M and Sigma-Aldrich are trademarks of Merck KGaA, Darmstadt, Germany or its affiliates. Detailed information on trademarks is available via publicly accessible resources. © 2018 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved. 9. McNay, J. L., et al., Protein unfolding during reversed-phase chromatography: II. Role of salt type and ionic strength. Biotechnol. Bioeng., 76(3), 233-240 (2001). 10. Ru, M. T., et al., Towards more active biocatalysts in organic media: increasing the activity of saltactivated enzymes. Biotechnol. Bioeng., 75(2), 187-196 (2001). 11. Rose, I., Acetate Kinase of Bacteria (Acetokinase), Meth. Enzymol., 1, 591-595 (1955)Precautions and Disclaimer This product is for R&D use only, not for drug, household, or other uses. Please consult the Material Safety Data Sheet for information regarding hazards and safe handling practices.The vibrant M and Sigma-Aldrich are trademarks of Merck KGaA, Darmstadt, Germany or its affiliates. Detailed information on trademarks is available via publicly accessible resources.© 2018 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.。
NI 9213 高密度温度计模块说明书
DAT ASHEETNI 921316 TC, ±78 mV, 24 Bit, 75 S/s Aggregate•Spring-terminal connectivity •50 Hz/60 Hz noise rejection•Up to 0.02 °C measurement sensitivity•250 Vrms, CAT II, channel-to-earth isolationThe NI 9213 is a high-density thermocouple module for CompactDAQ and CompactRIO chassis. Designed for higher-channel-count systems, the NI 9213 adds thermocouples to mixed-signal test systems without taking up too many slots.Kit ContentsAccessories •• NI 9213NI 9213 Getting Started Guide• NI 9940 Backshell Connector KitNI C Series OverviewNI provides more than 100 C Series modules for measurement, control, and communication applications. C Series modules can connect to any sensor or bus and allow for high-accuracy measurements that meet the demands of advanced data acquisition and control applications.•Measurement-specific signal conditioning that connects to an array of sensors and signals •Isolation options such as bank-to-bank, channel-to-channel, and channel-to-earth ground •-40 °C to 70 °C temperature range to meet a variety of application and environmentalneeds •Hot-swappable The majority of C Series modules are supported in both CompactRIO and CompactDAQ platforms and you can move modules from one platform to the other with no modification.2 | | NI 9213 DatasheetCompactRIOCompactRIO combines an open-embedded architecturewith small size, extreme ruggedness, and C Seriesmodules in a platform powered by the NI LabVIEWreconfigurable I/O (RIO) architecture. Each systemcontains an FPGA for custom timing, triggering, andprocessing with a wide array of available modular I/O tomeet any embedded application requirement. CompactDAQCompactDAQ is a portable, rugged data acquisition platformthat integrates connectivity, data acquisition, and signalconditioning into modular I/O for directly interfacing to anysensor or signal. Using CompactDAQ with LabVIEW, youcan easily customize how you acquire, analyze, visualize,and manage your measurement data.SoftwareLabVIEW Professional Development System for Windows•Use advanced software tools for large project development•Generate code automatically using DAQ Assistant and InstrumentI/O Assistant•Use advanced measurement analysis and digital signal processing•Take advantage of open connectivity with DLLs, ActiveX,and .NET objects•Build DLLs, executables, and MSI installersNI LabVIEW FPGA Module•Design FPGA applications for NI RIO hardware•Program with the same graphical environment used for desktop andreal-time applications•Execute control algorithms with loop rates up to 300 MHz•Implement custom timing and triggering logic, digital protocols, andDSP algorithms•Incorporate existing HDL code and third-party IP including Xilinx IPgenerator functions•Purchase as part of the LabVIEW Embedded Control and MonitoringSuiteNI 9213 Datasheet| © National Instruments| 3NI LabVIEW Real-Time Module•Design deterministic real-time applications with LabVIEWgraphical programming•Download to dedicated NI or third-party hardware for reliableexecution and a wide selection of I/O•Take advantage of built-in PID control, signal processing, andanalysis functions•Automatically take advantage of multicore CPUs or setprocessor affinity manually•Take advantage of real-time OS, development and debuggingsupport, and board support•Purchase individually or as part of a LabVIEW suiteNI 9213 CircuitryEach channel passes through a differential filter and then is multiplexed and sampled by a 24-bit analog-to-digital converter (ADC). The channels share a common ground, COM, that is isolated from other modules in the system.Figure 1. Input Circuitry for One Channel of the NI 9213Common-Mode VoltageThe NI 9213 common-mode range is the maximum voltage between any channel and COM. If COM is not connected, then the common-mode voltage range is the maximum voltage between any two channels. The NI 9213 measures the common-mode voltage level of each channel and returns a warning in the software if the signal is outside the common-mode voltage range.Open Thermocouple DetectionEach channel has an open thermocouple detection (OTD) circuit, which consists of a current source between the TC+ and TC- terminals. If an open thermocouple is connected to the channel, the current source forces a full-scale voltage across the terminals.4| | NI 9213 DatasheetInput ImpedanceEach channel has a resistor that produces an input impedance between the TC and COM terminals. The gain and offset errors resulting from the source impedance of connected thermocouples are negligible for most applications. Thermocouples with a higher lead resistance can introduce more significant errors.Thermocouple Measurement Accuracy Thermocouple measurement errors depend partly on the following factors:•the type of thermocouple•the accuracy of the thermocouple•the temperature that you are measuring•the resistance of the thermocouple wires•the cold-junction temperatureFor the best accuracy performance, follow these guidelines:•Set up the NI 9213 according to the getting started guide on /manuals to minimize thermal gradients across the NI 9213 terminals.•Use the autozero channel to compensate for offset errors.Cold-Junction AccuracyHeat dissipated by adjacent C Series modules or nearby heat sources can cause errors in thermocouple measurements by heating the NI 9213 terminals to a different temperature than the cold-junction compensation sensor. Thermal gradient across the terminals can cause the terminals of different NI 9213 channels to be at different temperatures, which creates accuracy errors and affects the relative accuracy between channels.The temperature measurement accuracy specifications include errors caused by the thermal gradient across the NI 9213 terminals for configurations with the NI 9213 terminals facing forward or upward.Autozero ChannelThe NI 9213 has an internal autozero channel, which can be subtracted from each thermocouple reading to compensate for offset errors. Use of the autozero channel is optional, however the NI 9213 specifications assume that autozero is applied to every sample. Refer to the documentation for the software that you are using with the NI 9213 for information about using the autozero channel.Timing ModesThe NI 9213 supports high-resolution and high-speed timing modes. High-resolution timing mode optimizes accuracy and noise and rejects power line frequencies. High-speed timing mode optimizes sample rate and signal bandwidth.NI 9213 Datasheet| © National Instruments| 5NI 9213 SpecificationsThe following specifications are typical for the range -40 °C to 70 °C unless otherwise noted.Caution Do not operate the NI 9213 in a manner not specified in this document.Product misuse can result in a hazard. You can compromise the safety protectionbuilt into the product if the product is damaged in any way. If the product isdamaged, return it to NI for repair.Warm-up time15 minutesInput CharacteristicsNumber of channels16 thermocouple channels, 1 internal autozerochannel, 1 internal cold-junction compensationchannelADC resolution24 bitsType of ADC Delta-SigmaSampling mode ScannedV oltage measurement range±78.125 mVTemperature measurement ranges Works over temperature ranges defined byNIST (J, K, T, E, N, B, R, S thermocoupletypes)Common-mode voltage rangeChannel-to-COM±1.2 V minimumCOM-to-earth ground±250 V1If you are using fewer than all channels, the sample rate might be faster. The maximum samplerate = 1/(Conversion Time x Number of Channels), or 100 S/s, whichever is smaller.Sampling faster than the maximum sample rate may result in the degradation of accuracy.2Including the autozero and cold-junction channels.6| | NI 9213 DatasheetCommon-mode rejection ratioHigh-resolution mode (at DC and 50 Hz to 60 Hz)Channel-to-COM100 dBCOM-to-earth ground>170 dBHigh-speed mode (at 0 Hz to 60 Hz)Channel-to-COM70 dBCOM-to-earth ground>150 dBInput bandwidthHigh-resolution mode14.4 HzHigh-speed mode78 Hz60 dBHigh-resolution noise rejection (at 50 Hz and60 Hz)Overvoltage protection±30 V between any two inputsDifferential input impedance78 MΩInput current50 nAInput noiseHigh-resolution mode200 nVrmsHigh-speed mode7 μVrmsGain errorHigh-resolution modeat 25 °C0.03% typicalat -40 °C to 70 °C0.07% typical, 0.15% maximum High-speed modeat 25 °C0.04% typicalat -40 °C to 70 °C0.08% typical, 0.16% maximumOffset errorHigh-resolution mode 4 μV typical, 6 μV maximumHigh-speed mode14 μV typical, 17 μV maximumOffset error from source impedance Add 0.05 μV per Ω, when source impedance>50 ΩNI 9213 Datasheet| © National Instruments| 7Cold-junction compensation accuracy0 °C to 70 °C0.8 °C typical, 1.7 °C maximum-40 °C to 70 °C 1.1 °C typical, 2.1 °C maximumMTBF852,407 hours at 25 °C;Bellcore Issue 2, Method 1,Case 3, LimitedPart Stress Method Temperature Measurement AccuracyMeasurement sensitivity3High-resolution modeTypes J, K, T, E, N<0.02 °CTypes B, R, S<0.15 °CHigh-speed modeTypes J, K, T, E<0.25 °CType N<0.35 °CType B<1.2 °CTypes R, S<2.8 °CThe following figures show the errors for each thermocouple type when connected to theNI 9213 with the autozero channel on. The figures display the maximum errors over a full temperature range and typical errors at room temperature. The figures account for gain errors, offset errors, differential and integral nonlinearity, quantization errors, noise errors, 50 Ω lead wire resistance, and cold-junction compensation errors. The figures do not account for the accuracy of the thermocouple itself.3Measurement sensitivity represents the smallest change in a temperature that a sensor can detect. It is a function of noise. The values assume the full measurement range of the standard thermocouple sensor according to ASTM E230-87.8| | NI 9213 DatasheetMeasured Temperature (°C )M e a s u r e m e n t E r r o r (°C )01342–2005030055080010501300Max (High speed), –40 to 70 °C Max (High res), –40 to 70 °CTyp (High res), room tempTyp (High speed), room temp Figure 3. Thermocouple T ype K ErrorsMeasured Temperature (°C )M e a s u r e m e n t E r r o r (°C )014532–200200400600800100012001400Max (High speed), –40 to 70 °C Max (High res), –40 to 70 °CTyp (High res), room tempTyp (High speed), room temp NI 9213 Datasheet | © National Instruments | 9Measured Temperature (°C)M e a s u r e m e n t E r r o r (°C )Max (High speed), –40 to 70 °C Max (High res), –40 to 70 °CTyp (High res), room tempTyp (High speed), room temp 0132–2002004006008001000Figure 5. Thermocouple T ype B ErrorsMeasured Temperature (°C )M e a s u r e m e n t E r r o r (°C )026420040060080010001200140016001800Max (High speed), –40 to 70 °C Max (High res), –40 to 70 °CTyp (High res), room tempTyp (High speed), room temp Figure 6. Thermocouple T ypes R and S ErrorsMeasured Temperature (°C )M e a s u r e m e n t E r r o r (°C )0264–200020040060080010001200140016001800Max (High speed), –40 to 70 °C Max (High res), –40 to 70 °CTyp (High res), room tempTyp (High speed), room temp 10 | | NI 9213 DatasheetPower RequirementsPower consumption from chassisActive mode490 mW maximumSleep mode25 μW maximumThermal dissipation (at 70 °C)Active mode840 mW maximumSleep mode710 mW maximumPhysical CharacteristicsGauge0.08 mm to 1.0 mm (28 AWG to 18 AWG)copper conductor wireWire strip length7 mm (0.28 in.) of insulation stripped from theendTemperature rating90 °C minimumWires per spring terminal One wire per spring terminalConnector securementSecurement type Screw flanges providedTorque for screw flanges0.2 N · m (1.80 lb · in.)Weight159 g (5.6 oz)Safety VoltagesConnect only voltages that are within the following limits:Between any two terminals±30 V maximumIsolationChannel-to-channel NoneChannel-to-earth groundContinuous250 Vrms, Measurement Category IIWithstand2,300 Vrms, verified by a 5 s dielectricwithstand testNI 9213 Datasheet| © National Instruments| 11Measurement Category II is for measurements performed on circuits directly connected to the electrical distribution system. This category refers to local-level electrical distribution, such as that provided by a standard wall outlet, for example, 115 V for U.S. or 230 V for Europe.Caution Do not connect the NI 9213 to signals or use for measurements withinMeasurement Categories III or IV.Hazardous LocationsU.S. (UL)Class I, Division 2, Groups A, B, C, D, T4;Class I, Zone 2, AEx nA IIC T4Canada (C-UL)Class I, Division 2, Groups A, B, C, D, T4;Class I, Zone 2, Ex nA IIC T4Europe (ATEX) and International (IECEx)Ex nA IIC T4 GcSafety and Hazardous Locations StandardsThis product is designed to meet the requirements of the following electrical equipment safety standards for measurement, control, and laboratory use:•IEC 61010-1, EN 61010-1•UL 61010-1, CSA 61010-1•EN 60079-0:2012, EN 60079-15:2010•IEC 60079-0: Ed 6, IEC 60079-15; Ed 4•UL 60079-0; Ed 5, UL 60079-15; Ed 3•CSA 60079-0:2011, CSA 60079-15:2012Note For UL and other safety certifications, refer to the product label or the OnlineProduct Certification section.Electromagnetic CompatibilityThis product meets the requirements of the following EMC standards for sensitive electrical equipment for measurement, control, and laboratory use:•EN 61326 (IEC 61326): Class A emissions; Industrial immunity•EN 55011 (CISPR 11): Group 1, Class A emissions•AS/NZS CISPR 11: Group 1, Class A emissions•FCC 47 CFR Part 15B: Class A emissions•ICES-001: Class A emissionsNote For the standards applied to assess the EMC of this product, refer to theOnline Product Certification section.Note For EMC compliance, operate this device with double-shielded cables.12| | NI 9213 DatasheetCE ComplianceThis product meets the essential requirements of applicable European Directives, as follows:•2014/35/EU; Low-V oltage Directive (safety)•2014/30/EU; Electromagnetic Compatibility Directive (EMC)•94/9/EC; Potentially Explosive Atmospheres (ATEX)Online Product CertificationRefer to the product Declaration of Conformity (DoC) for additional regulatory compliance information. To obtain product certifications and the DoC for this product, visit / certification, search by model number or product line, and click the appropriate link in the Certification column.Shock and VibrationTo meet these specifications, you must panel mount the system.Operating vibrationRandom (IEC 60068-2-64) 5 g rms, 10 Hz to 500 HzSinusoidal (IEC 60068-2-6) 5 g, 10 Hz to 500 HzOperating shock (IEC 60068-2-27)30 g, 11 ms half sine; 50 g, 3 ms half sine;18 shocks at 6 orientations EnvironmentalRefer to the manual for the chassis you are using for more information about meeting these specifications.-40 °C to 70 °COperating temperature(IEC 60068-2-1, IEC 60068-2-2)-40 °C to 85 °CStorage temperature(IEC 60068-2-1, IEC 60068-2-2)Ingress protection IP40Operating humidity (IEC 60068-2-78)10% RH to 90% RH, noncondensing Storage humidity (IEC 60068-2-78)5% RH to 95% RH, noncondensing Pollution Degree2Maximum altitude2,000 mIndoor use only.NI 9213 Datasheet| © National Instruments| 13Environmental ManagementNI is committed to designing and manufacturing products in an environmentally responsible manner. NI recognizes that eliminating certain hazardous substances from our products is beneficial to the environment and to NI customers.For additional environmental information, refer to the Minimize Our Environmental Impact web page at /environment. This page contains the environmental regulations and directives with which NI complies, as well as other environmental information not included in this document.Waste Electrical and Electronic Equipment (WEEE) EU Customers At the end of the product life cycle, all NI products must bedisposed of according to local laws and regulations. For more information abouthow to recycle NI products in your region, visit /environment/weee.电子信息产品污染控制管理办法(中国RoHS)中国客户National Instruments符合中国电子信息产品中限制使用某些有害物质指令(RoHS)。
REACHSVHC清单181项英文版
REACHSVHC清单181项英文版REACH SVHC FinderREACH SVHC Finder is a free tool developed by CSP to help you quickly search if a chemical substance belongs to Substance of Very High Concern (SVHC)under EU REACH regulation or not and whether it is subject to REACH authorization. It allows you to search both SVHC list and authorization list at the same time.SVHCs which have been added to authorization list cannot be placed on the market or used after sunset date, unless an authorization is granted for their specific use, or the use is exempted from authorisation. More info about REACH SVHC and your obligations can be found here. Please also try another useful tool called REACH Restricted Substances Finder (RRS Finder).Please note that the CAS no. given below is not an-exhaustive list. There are currently 181SVHCs [Updated: 16 Jan 2018].Index Substance Name EC No. CAS No. InclusionDate(M/D/Y)If OnAuthorizationList andSunset Date?181 Benz[a]anthracene 200-280-6 56-55-3,1718-53-21/15/2018180 Cadmium carbonate 208-168-9 513-78-0 1/15/2018 179 Cadmium hydroxide 244-168-5 21041-95-2 1/15/2018 178 Cadmium nitrate 233-710-6 10022-68-1,10325-94-71/15/2018177 Chrysene 205-923-4 218-01-9, 1719-03-51/15/2018176 Dodecachloropentacyclo[12.2.1 .16,9.02,13.05,10]octadeca-7,15-diene ("Dechlorane Plus"?)- - 1/15/2018175 Reaction products of1,3,4-thiadiazolidine-2,5-dit hione, formaldehyde and4-heptylphenol, branched and linear (RP-HP)- - 1/15/2018174 Perfluorohexane-1-sulphonic acid and its salts (PFHxS)- - 7/7/2017173 4,4'-isopropylidenediphenol (bisphenol A)201-245-8 80-05-7 1/12/2017172 nonadecafluorodecanoic acid (PFDA) and its sodium and ammonium salts206-400-3 335-76-2 1/12/2017 171 4-heptylphenol, branched and linear (4-HPbl)- - 1/12/2017170 p-(1,1-dimethylpropyl)phenol (PTAP)201-280-9 80-46-6 1/12/2017Index Substance Name EC No. CAS No. Date(M/D/Y) Authorization List and Sunset Date?169 Benzo[def]chrysene 200-028-5 50-32-8 6/20/2016 168 Nitrobenzene 202-716-0 98-95-3 12/17/2015167 2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol(UV-327)223-383-8 3864-99-1 12/17/2015166 2-(2H-benzotriazol-2-yl)-4-(tert-butyl)-6-(sec-butyl)phenol (UV-350)253-037-1 36437-37-3 12/17/2015165 1,3-propanesultone 214-317-9 1120-71-4 12/17/2015 164 Perfluorononan-1-oic-acid andits sodium and ammonium salts206-801-3375-95-1,21049-39-8,4149-60-412/17/2015163 1,2-benzenedicarboxylic acid,di-C6-10-alkyl esters;1,2-benzenedicarboxylic acid,mixed decyl and hexyl and octyldiesters with ≥ 0.3% ofdihexyl phthalate (EC No.201-559-5)271-094-0,272-013-168515-51-5,68648-93-16/15/2015162 5-sec-butyl-2-(2,4-dimethylcy clohex-3-en-1-yl)-5-methyl-1,3-dioxane [1],5-sec-butyl-2-(4,6-dimethylcy clohex-3-en-1-yl)-5-methyl-1,3-dioxane [2] [covering any ofthe individual stereoisomers of [1] and [2] or any combination thereof]6/15/2015161 Bis (2-ethylhexyl)phthalate (DEHP)204-211-0 117-81-72014/12/17;2008/10/28Yes,02/21/2015160 2-(2H-benzotriazol-2-yl)-4,6- ditertpentylphenol (UV-328)247-384-8 25973-55-1 12/17/2014 159 2-benzotriazol-2-yl-4,6-di-te rt-butylphenol (UV-320)223-346-6 3846-71-7 12/17/2014 158 2-ethylhexyl10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (DOTE)239-622-4 15571-58-1 12/17/2014157 Cadmium fluoride 232-222-0 7790-79-6 12/17/2014Index Substance Name EC No. CAS No. Date(M/D/Y) Authorization List and Sunset Date?156 Cadmium sulphate 233-331-6 10124-36-4,31119-53-612/17/2014155 reaction mass of 2-ethylhexyl10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate and 2-ethylhexyl10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (reactionmass of DOTE and MOTE)12/17/2014154 1,2-Benzenedicarboxylic acid,dihexylester, branched andlinear271-093-5 68515-50-4 6/16/2014153 Cadmium chloride 233-296-7 10108-64-2 6/16/2014152 Sodium perborate,perboricacid, sodium salt239-172-9,234-390-06/16/2014151 Sodium peroxometaborate 231-556-4 7632-4-4, 6/16/2014 150 Cadmium sulphide 215-147-8 1306-23-612/16/2013 149 Dihexyl phthalate 201-559-5 84-75-3 12/16/2013148 Disodium3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalene-1-sulphonate) (C.I.Direct Red 28)209-358-4 573-58-0 12/16/2013147 Disodium4-amino-3-[[4'-[(2,4-diaminophenyl)azo][1,1'-biphenyl]-4-yl]azo]-5-hydroxy-6-(phenylazo)naphthalene-2,7-disulphonate (C.I.Direct Black 38)217-710-3 1937-37-7 12/16/2013146 Imidazolidine-2-thione(2-imidazoline-2-thiol)202-506-9 96-45-7 12/16/2013145 Lead di(acetate) 206-104-4 301-04-2 12/16/2013 144 Trixylyl phosphate 246-677-8 25155-23-1 12/16/2013 143 4-Nonylphenol, branched andlinear, ethoxylated[substances with a linearand/or branched alkyl chain6/20/2013Yes,01/04/2021Index Substance Name EC No. CAS No. Date(M/D/Y) Authorization List and Sunset Date?with a carbon number of 9 covalently bound in position 4 to phenol, ethoxylated covering UVCB- and well-defined substances, polymers and homologues, which include any of the individual isomersand/or combinations thereof]142 Ammoniumpentadecafluorooctanoate(APFO)223-320-4 3825-26-1 6/20/2013141 Cadmium 231-152-8 7440-43-9 6/20/2013 140 Cadmium oxide 215-146-2 1306-19-0 6/20/2013139 Dipentyl phthalate (DPP) 205-017-9 131-18-0 6/20/2013 Yes,07/04/2020138 Pentadecafluorooctanoic acid(PFOA)206-397-9 335-67-1 6/20/2013137 1,2-Benzenedicarboxylic acid,dipentylester, branched andlinear284-032-2 84777-06-0 12/19/2012Yes,07/04/2020136 1,2-Diethoxyethane 211-076-1 629-14-1 12/19/2012135 1-bromopropane (n-propylbromide)203-445-0 106-94-5 12/19/2012Yes,07/04/2020134 3-ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine421-150-7 143860-04-2 12/19/2012133 4,4'-methylenedi-o-toluidine 212-658-8 838-88-0 12/19/2012 132 4,4'-oxydianiline and its salts 202-977-0 101-80-4 12/19/2012131 4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated [coveringwell-defined substances andUVCB substances, polymers andhomologues]12/19/2012130 4-Aminoazobenzene 200-453-6 60-09-3 12/19/2012129 4-methyl-m-phenylenediamine(toluene-2,4-diamine)202-453-1 95-80-7 12/19/2012128 4-Nonylphenol, branched andlinear [substances with alinear and/or branched alkylchain with a carbon number of 9covalently bound in position 412/19/2012Index Substance Name EC No. CAS No.Date(M/D/Y)AuthorizationList andSunset Date?to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof] 127 6-methoxy-m-toluidine(p-cresidine)204-419-1120-71-8 12/19/2012126 [Phthalato(2-)]dioxotrilead 273-688-5 69011-06-9 12/19/2012125 Acetic acid, lead salt, basic 257-175-3 51404-69-4 12/19/2012 124 Biphenyl-4-ylamine 202-177-1 92-67-1 12/19/2012 123Bis(pentabromophenyl) ether (decabromodiphenyl ether) (DecaBDE)214-604-9 1163-19-5 12/19/2012122Cyclohexane-1,2-dicarboxylic anhydride [1],cis-cyclohexane-1,2-dicarboxy lic anhydride [2],trans-cyclohexane-1,2-dicarbo xylic anhydride [3] [The individual cis- [2] and trans- [3] isomer substances and all possible combinations of the cis- and trans-isomers [1] are covered by this entry] 201-604-9, 236-086-3, 238-009-9 85-42-7, 13149-00-3, 14166-21-312/19/2012 121 Diazene-1,2-dicarboxamide(C,C`-azodi(formamide)) (ADCA)204-650-8123-77-3 12/19/2012120 Dibutyltin dichloride (DBTC) 211-670-0 683-18-1 12/19/2012 119 Diethyl sulphate 200-589-6 64-67-5 12/19/2012 118 Diisopentylphthalate210-088-4605-50-5 12/19/2012Yes,07/04/2020117 Dimethyl sulphate 201-058-1 77-78-1 12/19/2012 116 Dinoseb(6-sec-butyl-2,4-dinitropheno l)201-861-7 88-85-712/19/2012115 Dioxobis(stearato)trilead 235-702-8 12578-12-0 12/19/2012 114 Fatty acids, C16-18, lead salts 292-966-7 91031-62-8 12/19/2012 113 Furan 203-727-3 110-00-9 12/19/2012 112 Henicosafluoroundecanoic acid 218-165-4 2058-94-8 12/19/2012 111Heptacosafluorotetradecanoicacid206-803-4376-06-712/19/2012Index Substance Name EC No. CAS No.Date(M/D/Y)AuthorizationList andSunset Date?110Hexahydromethylphthalic anhydride [1],Hexahydro-4-methylphthalic anhydride [2],Hexahydro-1-methylphthalic anhydride [3], Hexahydro-3-methylphthalic anhydride [4] [The individual isomers [2], [3] and [4] (including their cis- and trans- stereo isomeric forms) and all possible combinations of the isomers [1] are covered by this entry]247-094-1, 243-072-0, 256-356-4, 260-566-1 25550-51-0,19438-60-9,48122-14-1, 57110-29-912/19/2012109 Lead bis(tetrafluoroborate) 237-486-0 13814-96-5 12/19/2012 108 Lead cyanamidate 244-073-9 20837-86-9 12/19/2012 107 Lead dinitrate 233-245-9 10099-74-8 12/19/2012 106 Lead monoxide (lead oxide) 215-267-0 1317-36-8 12/19/2012 105 Lead oxide sulfate 234-853-7 12036-76-9 12/19/2012 104 Lead titanium trioxide 235-038-9 12060-00-3 12/19/2012 103 Lead titanium zirconium oxide 235-727-4 12626-81-2 12/19/2012 102 Methoxyacetic acid 210-894-6 625-45-6 12/19/2012 101 Methyloxirane (Propyleneoxide)200-879-275-56-9 12/19/2012100 N,N-dimethylformamide 200-679-5 68-12-2 12/19/2012 99 N-methylacetamide 201-182-6 79-16-312/19/201298 N-pentyl-isopentylphthalate776297-69-9 12/19/2012Yes,07/04/202097 o-aminoazotoluene 202-591-2 97-56-3 12/19/2012 96 o-Toluidine 202-429-0 95-53-4 12/19/2012 95 Orange lead (lead tetroxide) 215-235-6 1314-41-6 12/19/2012 94 Pentacosafluorotridecanoicacid276-745-272629-94-8 12/19/2012 93 Pentalead tetraoxide sulphate 235-067-7 12065-90-6 12/19/2012 92Pyrochlore, antimony leadyellow232-382-18012-00-8 12/19/201291 Silicic acid (H2Si2O5), barium salt (1:1), lead-doped [withlead (Pb) content above the applicable generic272-271-568784-75-8 12/19/2012Index Substance Name EC No. CAS No. Date(M/D/Y) Authorization List and Sunset Date?concentration limit for ’toxicity for reproduction’Repr. 1A (CLP) or category 1(DSD),the substance is a memberof the group entry of leadcompounds, with index number082-001-00-6 in Regulation (EC)No 1272/2008]90 Silicic acid, lead salt 234-363-3 11120-22-2 12/19/201289 Sulfurous acid, lead salt,dibasic263-467-1 62229-08-7 12/19/201288 Tetraethyllead 201-075-4 78-00-2 12/19/2012 87 Tetralead trioxide sulphate 235-380-9 12202-17-4 12/19/2012 86 Tricosafluorododecanoic acid 206-203-2 307-55-1 12/19/201285 Trilead bis(carbonate)dihydroxide215-290-6 1319-46-6 12/19/201284 Trilead dioxide phosphonate 235-252-2 12141-20-7 12/19/201283 1,2-bis(2-methoxyethoxy)ethane (TEGDME,triglyme)203-977-3 112-49-2 6/18/2012 82 1,2-dimethoxyethane,ethylene glycol dimethyl ether (EGDME) 203-794-9 110-71-4 6/18/2012 81 1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC)219-514-3 2451-62-9 6/18/2012 80 1,3,5-tris[(2S and2R)-2,3-epoxypropyl]-1,3,5-tr iazine-2,4,6-(1H,3H,5H)-trione (β-TGIC)423-400-0 59653-74-6 6/18/2012 79 4,4'-bis(dimethylamino)-4''-( methylamino)trityl alcohol [with ≥ 0.1% of Michler'sketone (EC No. 202-027-5) or Michler's base (EC No.202-959-2)]209-218-2 561-41-1 6/18/2012 78 4,4'-bis(dimethylamino)benzop henone (Michler’s ketone)202-027-5 90-94-8 6/18/201277 [4-[4,4'-bis(dimethylamino) benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammon ium chloride (C.I. Basic Violet208-953-6 548-62-9 6/18/2012Index Substance Name EC No. CAS No.Date(M/D/Y)AuthorizationList andSunset Date?3) [with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)]76[4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methyle ne]cyclohexa-2,5-dien-1-ylide ne] dimethylammonium chloride(C.I. Basic Blue 26) [with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)] 219-943-6 2580-56-5 6/18/201275 Diboron trioxide 215-125-8 1303-86-2 6/18/2012 74 Formamide 200-842-0 75-12-7 6/18/2012 73 Lead(II) bis(methanesulfonate) 401-750-5 17570-76-2 6/18/2012 72 N,N,N',N'-tetramethyl-4,4'-methylenedianiline (Michler ’s base) 202-959-2 101-61-16/18/201271α,α-Bis[4-(dimethylamino)phenyl]-4(phenylamino)naphthalene-1-methanol (C.I. Solvent Blue 4) [with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)] 229-851-8 6786-83-0 6/18/201270 1,2-Dichloroethane203-458-1107-06-2 12/19/2011Yes,11/22/201769 2,2'-dichloro-4,4'-methylenedianiline (MOCA)202-918-9101-14-4 12/19/2011Yes,11/22/201768 2-Methoxyaniline,o-Anisidine 201-963-1 90-04-0 12/19/2011674-(1,1,3,3-tetramethylbutyl)phenol205-426-2140-66-912/19/2011Yes,01/04/202166Aluminosilicate Refractory Ceramic Fibres are fibres covered by index number650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European12/19/2011Index Substance Name EC No. CAS No.Date(M/D/Y)AuthorizationList andSunset Date?Parliament and of the Council of 16 December 2008 onclassification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium and silicon are the main components present (in the fibres) within variableconcentration ranges b) fibres have a length weightedgeometric mean diameter less two standard geometric errors of 6 or less micrometres (μm) c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight65 Arsenic acid231-901-9 7778-39-4 12/19/2011Yes,08/22/2017 64 Bis(2-methoxyethyl) ether203-924-4111-96-6 12/19/2011Yes,08/22/2017 63 Bis(2-methoxyethyl) phthalate 204-212-6 117-82-8 12/19/2011Yes,07/04/202062 Calcium arsenate231-904-5 7778-44-1 12/19/201161 Dichromium tris(chromate)246-356-224613-89-6 12/19/2011Yes,01/22/2019 60 Formaldehyde, oligomericreaction products with aniline 500-036-125214-70-4 12/19/2011Yes,08/22/201759 Lead diazide, Lead azide 236-542-1 13424-46-9 12/19/2011 58 Lead dipicrate 229-335-2 6477-64-1 12/19/2011 57 Lead styphnate 239-290-0 15245-44-0 12/19/2011 56 N,N-dimethylacetamide 204-826-4 127-19-5 12/19/201155 Pentazinc chromateoctahydroxide 256-418-049663-84-5 12/19/2011Yes,01/22/201954 Phenolphthalein 201-004-7 77-09-8 12/19/2011 53 Potassiumhydroxyoctaoxodizincatedichro mate234-329-8 11103-86-9 12/19/2011Yes, 01/22/2019 52Trilead diarsenate 222-979-53687-31-8 12/19/2011Index Substance Name EC No. CAS No. Date(M/D/Y) Authorization List and Sunset Date?51 Zirconia AluminosilicateRefractory Ceramic Fibres arefibres covered by index number650-017-00-8 in Annex VI, part3, table 3.1 of Regulation (EC)No 1272/2008 of the EuropeanParliament and of the Council of16 December 2008 onclassification, labelling andpackaging of substances andmixtures, and fulfil the threefollowing conditions: a) oxidesof aluminium, silicon andzirconium are the maincomponents present (in thefibres) within variableconcentration ranges b) fibreshave a length weightedgeometric mean diameter lesstwo standard geometric errorsof 6 or less micrometres (μm).c) alkaline oxide and alkaliearth oxide(Na2O+K2O+CaO+MgO+BaO) contentless or equal to 18% by weight12/19/201150 Cobalt dichloride 231-589-4 7646-79-9 2011/06/20 - 2008/10/2849 1,2,3-trichloropropane 202-486-1 96-18-4 6/20/2011 48 1,2-Benzenedicarboxylic acid,di-C6-8-branched alkyl esters,C7-rich276-158-1 71888-89-6 6/20/2011Yes,07/04/202047 1,2-Benzenedicarboxylic acid,di-C7-11-branched and linearalkyl esters271-084-6 68515-42-4 6/20/201107/04/202046 1-Methyl-2-pyrrolidone (NMP) 212-828-1 872-50-4 6/20/2011 45 2-Ethoxyethyl acetate 203-839-2 111-15-9 6/20/201144 Hydrazine 206-114-9 302-01-2,7803-57-86/20/201143 Strontium chromate 232-142-6 7789-6-2, 6/20/2011 Yes,Index Substance Name EC No. CAS No.Date(M/D/Y)AuthorizationList andSunset Date? 01/22/201942 2-Ethoxyethanol 203-804-1 110-80-5 12/15/2010 412-Methoxyethanol 203-713-7 109-86-412/15/201040Acids generated from chromium trioxide and their oligomers. Names of the acids and theiroligomers: Chromic acid,Dichromic acid, Oligomers of chromic acid and dichromic acid.231-801-5,236-881-57738-94-5, 13530-68-2 12/15/2010Yes,09/21/201739 Chromium trioxide 215-607-8 1333-82-0 12/15/201009/21/201738Cobalt(II) carbonate 208-169-4 513-79-1 12/15/2010 37 Cobalt(II) diacetate 200-755-8 71-48-7 12/15/2010 36 Cobalt(II) dinitrate 233-402-1 10141-05-6 12/15/2010 35 Cobalt(II) sulphate 233-334-2 10124-43-3 12/15/201034 Ammonium dichromate 232-143-1 7789-9-5, 6/18/2010Yes,09/21/201733Boric acid233-139-2, 234-343-4 10043-35-3,11113-50-1 6/18/201032Disodium tetraborate, anhydrous215-540-41303-96-4,1330-43-4, 12179-04-36/18/2010 31 Potassium chromate 232-140-5 7789-00-6 6/18/2010Yes,09/21/2017 30 Potassium dichromate 231-906-6 7778-50-9 6/18/2010Yes,09/21/2017 29 Sodium chromate 231-889-5 7775-11-3, 6/18/2010Yes,09/21/2017 28 Tetraboron disodium heptaoxide, hydrate 235-541-3 12267-73-1 6/18/201027 Trichloroethylene 201-167-4 79-01-66/18/2010Yes,04/21/201626 Acrylamide201-173-779-06-1 3/30/201025 2,4-Dinitrotoluene (2,4-DNT) 204-450-0 121-14-2 1/13/2010Yes,08/21/2015 24 Anthracene oil292-602-7 90640-80-5 1/13/2010Yes,10/04/2020 23Anthracene oil, anthracene paste292-603-290640-81-6 1/13/2010Index Substance Name EC No. CAS No.Date(M/D/Y)AuthorizationList andSunset Date?22 Anthracene oil, anthracenepaste, anthracene fraction 295-275-991995-15-2 1/13/2010 21 Anthracene oil, anthracenepaste, distn. lights295-278-591995-17-4 1/13/201020 Anthracene oil, anthracene-low 292-604-8 90640-82-71/13/201019 Diisobutyl phthalate (DIBP) 201-553-2 84-69-5 1/13/2010Yes,02/21/2015 18Lead chromate231-846-07758-97-6 1/13/2010Yes,05/21/2015 17Lead chromate molybdatesulphate red (C.I. Pigment Red 104) 235-759-9 12656-85-8 1/13/2010Yes,05/21/201516 Lead sulfochromate yellow (C.I.Pigment Yellow 34)215-693-71344-37-2 1/13/2010 Yes,05/21/2015 15 Pitch, coal tar, high temp. 266-028-2 65996-93-2 1/13/2010Yes,10/04/2020 14 Tris(2-chloroethyl)phosphate 204-118-5 115-96-8 1/13/2010Yes,08/21/2015 13 4,4'- Diaminodiphenylmethane(MDA)202-974-4101-77-9 10/28/2008Yes,08/21/2014 12 5-tert-butyl-2,4,6-trinitro-m-xylene (Musk xylene)201-329-481-15-2 10/28/2008Yes,08/21/2014 11 Alkanes, C10-13, chloro (ShortChain Chlorinated Paraffins) 287-476-585535-84-8 10/28/2008 10 Anthracene 204-371-1 120-12-7 10/28/200809 Benzyl butyl phthalate (BBP) 201-622-7 85-68-7 10/28/2008Yes,02/21/201508 Bis(tributyltin) oxide (TBTO) 200-268-0 56-35-9 10/28/200807 Diarsenic pentaoxide 215-116-9 1303-28-2 10/28/2008Yes,05/21/2015 06 Diarsenic trioxide 215-481-4 1327-53-3 10/28/2008Yes,05/21/2015 05Dibutyl phthalate (DBP)201-557-484-74-2 10/28/2008Yes,02/21/201504Hexabromocyclododecane (HBCDD) and all major diastereoisomers identified: Alpha-hexabromocyclododecane Beta-hexabromocyclododecane Gamma-hexabromocyclododecane247-148-4, 221-695-9 25637-99-4, 3194-55-6, 134237-50-6, 134237-51-7,10/28/2008Yes,08/21/2015Index Substance Name EC No. CAS No. Date(M/D/Y) Authorization List and Sunset Date?134237-52-803 Lead hydrogen arsenate 232-064-2 7784-40-9 10/28/200802 Sodium dichromate 234-190-3 7789-12-0,10588-01-910/28/2008Yes,09/21/201701 Triethyl arsenate 427-700-2 15606-95-8 10/28/2008。
Glucose Oxidase Activity Assay Kit 产品说明书
Glucose Oxidase Activity Assay KitCatalog Number MAK097Storage Temperature –20 CTECHNICAL BULLETINProduct DescriptionGlucose Oxidase (GOx, EC 1.1.3.4) is an enzyme found in insects, fungi, and bacteria that catalyzes the oxidation of D-glucose to D-gluconolactone. GOx is widely used in the food, beverage, chemical, and pharmaceutical industries.The Glucose Oxidase Activity Assay Kit provides a simple and direct procedure for measuring GOx activity in a variety of biological samples. GOx activity is determined by a coupled enzyme assay, in which GOx oxidizes D-glucose resulting in the production of hydrogen peroxide (H2O2) that reacts with a probe, generating a colorimetric (570 nm)/fluorometric(ex = 535/em = 587 nm) product, proportional to the GOx present. One unit of GOx is defined as the amount of enzyme that generates 1.0 mole of H2O2 per minute at 37 C.ComponentsThe kit is sufficient for 100 assays in 96 well plates. GOx Assay Buffer 28 mL Catalog Number MAK097AFluorescent Peroxidase Substrate, in DMSO 0.2 mL Catalog Number MAK097BGOx Substrate 1 mL Catalog Number MAK097CGOx Developer 1 vl Catalog Number MAK097DGOx Positive Control 1 vl Catalog Number MAK097EH2O2 Standard, 0.88 M 0.1 mL Catalog Number MAK097F Reagents and Equipment Required but NotProvided.96 well flat-bottom plate – It is recommended to useblack plates with clear bottoms for fluorescenceassays and clear plates for colorimetric assays.Fluorescence or spectrophotometric multiwell plate readerPrecautions and DisclaimerThis product is for R&D use only, not for drug, household, or other uses. Please consult the Safety Data Sheet for information regarding hazards and safe handling practices.Preparation InstructionsBriefly centrifuge vials before opening. To maintain reagent integrity, avoid repeated freeze/thaw cycles.GOx Assay Buffer – Allow buffer to come to room temperature before use.Fluorescent Peroxidase Substrate – Allow reagent to come to room temperature before use. Mix well by pipetting, then aliquot and store, protected fromlight and moisture, at –20 C. Upon thawing, theFluorescent Peroxidase Substrate is ready-to-usein the colorimetric assay.For the fluorescence assay, dilute an aliquot of the Fluorescent Peroxidase Substrate 5 to 10-fold with GOx Assay Buffer, just prior to use. This will reduce the background of the fluorescence assay.GOx Developer and GOx Positive Control –Reconstitute each in 220 L of GOx Assay Buffer.Mix well by pipetting (don’t vortex), then aliquoteach and store at –20 C. Use within two months of reconstitution and keep cold while in use.Storage/StabilityThe kit is shipped on wet ice. Storage at –20 C, protected from light, is recommended.2 ProcedureAll samples and standards should be run in duplicate. Use ultrapure water for the preparation of standards.H2O 2Standards for Colorimetric Detection22prepare a 10 mM standard solution. Further dilute the 10 mM standard to 0.5 mM by diluting 50 l of the 10 mM standard solution with 950 l of GOx Assay Buffer. Add 0, 2, 4, 6, 8, 10 L of the 0.5 mM standard solution into a 96 well plate, generating 0 (blank), 1, 2, 3, 4, and 5 nmole/well standards. Add GOx Assay Buffer to each well to bring the volume to 50 L.H 2O 2 Standards for Fluorometric Detection Prepare a 0.5 mM standard solution as for thecolorimetric assay. Dilute 10 L of the 0.5 mM standard solution with 90 L of the GOx Assay Buffer to make a 50 M standard solution. Add 0, 2, 4, 6, 8, 10 L of the prepared 50 M standard solution into a 96 well plate, generating 0 (blank), 0.1, 0.2, 0.3, 0.4, and0.5 nmole/well standards. Add GOx Assay Buffer to each well to bring the volume to 50 L.Sample PreparationBoth the colorimetric and fluorometric assays require 50 L of sample for each reaction (well).Tissue (10 mg) or cells (1 106) should be rapidly homogenized with 100–200 L of GOx Assay Buffer. Centrifuge at 15,000 g for 10 minutes to remove insoluble materials. Bring samples to a final volume of 50 L with GOx Assay Buffer.Serum samples can be directly added to wells. Add 1–50 L samples into wells of a 96 well plate. Bring samples to final volume of 50 L with GOx Assay Buffer.For unknown samples, it is suggested to test several sample volumes to make sure the readings are within the standard curve range.Notes: High background may be a problem for some samples. To remove the effect of background, a sample blank may be set up for each sample by omitting the GOx Substrate.For the positive control (optional), add 2–10 L of the GOx Positive Control to wells.Assay Reaction1. Set up the Reaction Mixes according to the schemein Table 1. 50 L of the appropriate Reaction Mix is required for each reaction (well).Table 1.Reaction Mixes 36 L 46 L 2 L 2 L 2 L 2 L10 L 2. Add 50 L of the appropriate Reaction Mix to eachwell. Mix well using a horizontal shaker or by pipetting.3. After 5 minutes, take the initial measurement(T initial ). For colorimetric assays, measure theabsorbance at 570 nm (A 570)initial . For fluorometric assays, measure fluorescence intensity (FLU initial , ex = 535/em = 585 nm).4. Incubate the plate at 37 C taking measurements(A 570 or FLU) every 2–3 minutes. Protect the plate from light during the incubation.5. Continue taking measurements until the value ofthe most active sample is greater than the value of the highest standard (Colorimetric – 5 nmole/well or fluorometric – 0.5 nmole/well). At this time the most active sample is near or exceeds the end of the linear range of the standard curve.6. The final measurement [(A 570)final or FLU final ] forcalculating the enzyme activity would bepenultimate reading or the value before the most active sample is near or exceeds the end of the linear range of the standard curve, see step 5. The time of the penultimate reading is T final .Note: It is essential the final measurement falls within the linear range of the standard curve.3 ResultsCalculationsCorrect for the background by subtracting the final measurement [(A570)final or FLU final] obtained for the0 (blank) standard from the final measurement [(A570)final or FLU final] of the standards. Plot the H2O2 standard curve.Note: A new standard curve must be set up each time the assay is run. Calculate the change in measurement from T initial to T final for samples and sample blanks.A570 = (A570)final– (A570)initialorFLU = FLU final– FLU initialAlso, subtract the Sample Blank measurement value from the sample measurement values. Compare the measurement value (A570 or FLU) of each sample to the standard curve to determine the amount of H2O2 generated by the oxidase assay between T initial and T final (B).The Glucose Oxidase activity of a sample may be determined by the following equation:GOx Activity = B Sample Dilution Factor(Reaction Time) VB = Amount (nmole) of H2O2 generated between T initialand T finalReaction Time = T final– T initial (minutes)V = sample volume (mL) added to wellGOx activity reported as nmole/min/mL = milliunit/mL, where one unit of GOx is defined as the amount of enzyme that generates 1.0 mole of H2O2 per minute at 37 C.4KVG,LS,MF,MAM 03/16-1 2016 Sigma-Aldrich Co. LLC. All rights reserved. SIGMA-ALDRICH is a trademark of Sigma-Aldrich Co. LLC, registered in the US and other countries. Sigma brand products are sold through Sigma-Aldrich, Inc. Purchaser must determine the suitability of the product(s) for their particular use. Additional terms and conditions may apply. Please see product information on the Sigma-Aldrich website at and/or on the reverse side of the invoice or packing slip.。
Sodium Azide说明书
Section 1- Product InformationProduct Name Sodium AzideSection 2-Composition / information on ingredientsSubstance/Preparation: SubstanceIngredient Name Sodium AzideCAS No. 26628-22-8EC Number RC0520EU Symbol T+,NR-Phrases R28,R32Note: See section 8 for occupational exposure limits and section 11 for LC50/LD50 informationSection 3- Hazards IdentificationPrimary hazards and critical effects Danger!May be fatal if absorbed through skin or if swallowed.May cause damage to the following organs: liver, brain, digestive system, centralnervous system, head.May be harmful to environment if released in large amounts.Do not get in eyes, on skin or on clothing. Do not ingest. Wash thoroughly afterhandling.Avoid contact of spilled material and runoff with soil and surface waterways. Physical/chemical hazards Not applicable.Human health hazards Very toxic if swallowed.Contact with acids liberates very toxic gas.Environmental hazards Very toxic to aquatic organisms. May cause long-term adverse effects in the aquaticenvironment.Section 4- First Aid MeasuresInhalation Ingestion If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately.Skin Contact In case of contact, immediately flush skin with plenty of water.Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughlyclean shoes before reuse. Get medical attention.Eye Contact In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Get medical attention.Notes to Medical Doctor Not available.Section 5- Fire Fighting MeasuresExtinguishing Media Use foam or all purpose dry chemicals to extinguish. This material is very toxic toaquatic organisms.Fire water contaminated with this material must be contained and prevented frombeing discharged to any waterway, sewer or drain.Fire-Fighting Procedures Fire fighters should wear positive pressure self-contained breathing apparatus(SCBA) and full turnout gear.Fire/Explosion Hazards Not applicableHazardous Decomposition Products These products are nitrogen oxides (NO, NO2...). Some metallic oxides.Section 6- Accidental Release MeasuresPersonal precautions Immediately contact emergency personnel. Keep unnecessary personnel away. Usesuitable protective equipment (Section 8).Follow all fire fighting procedures (Section 5).Environmental Precautions and Clean-up Methods If emergency personnel are unavailable vacuum or carefully scoop up spilled materials and place in an appropriate container for disposal.Avoid creating dusty conditions and prevent wind dispersal. Minimize contact of spilled material with soils to prevent runoff to surface waterways.Material Safety Data SheetDate Created 06/10/2010Date Updated 12/18/2012Email ******************Section 7- Handling and StorageHandlingDo not get in eyes, on skin or on clothing. Do not ingest. Wash thoroughly after handling. Avoid contact of spilled material and runoff with soil and surface waterways. StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Packaging materials Use original container.Section 8- Exposure Controls/Personal Protection EquipmentOccupational Exposure Limits Not available Engineering controlsOpen handling is not permitted. All handling must be performed in a glove box or other totally enclosed system. Personal protective equipmentRespiratory SystemUse an approved, properly fitted, HEPA filter cartridge respirator, or a respirator of greater protection if there is the potential to exceed the exposure limit(s). Skin and bodyDisposable outer garments, or impervious garments of equal or greater protection. Hands Use chemical resistant, impervious gloves.Additional body garments should be used based upon the task being performed(e.g., sleevelets, apron, gauntlets, disposable suits) to avoid exposed skin surfaces.Appropriate techniques should be used to remove potentially contaminated clothing.EyesSafety glasses. Goggles, face shield, or other full-face protection if potential existsfor direct exposure to dust.Protective Clothing (Pictograms)Section 9- Physical and Chemical PropertiesFlash point Not availableSection 10- Stability and ReactivityStability The product is stable. Conditions and Materials to avoidReactive with metals, acids. Hazardous Decomposition Products Not availableSection 11- Toxicological InformationToxicity DataTest LD50 LD50 LD50 LD50 LDLo LDLo LDLo Result 27 mg/kg 27 mg/kg 23.7 mg/kg 20 mg/kg 129 mg/kg 143 mg/kg 29 mg/kg Route Oral Oral Oral Dermal Oral Oral Oral SpeciesRatMouseBirdsRabbitsHumanHumanHumanRoutes of Entry Absorbed through skin. Dermal contact. Eye contact. Inhalation.Ingestion.Acute toxicity Ingestion Very toxic if swallowed.Skin Contact Very toxic in contact with skin.Chronic toxicityAdverse Effects Adverse symptoms may include: nausea/vomiting headache blood pressure lowered nerve damagecentral nervous system depression liver abnormalities cerebral (brain) pathology.Target Organs May cause damage to the following organs: liver, brain, digestive system, central nervous system(CNS), head.Carcinogenic Effects Not availableMutagenic Effects Not availableDevelopmental and Teratogenic EffectsNot availableReproductive Effects Not availableOther Information Repeated exposure to a highly toxic material may produce general deterioration of health by anaccumulation in one or many human organs.Section 12- Ecological InformationEcotoxicity Data Species Not availableavailablePeriod NotavailableResult NotSection 13- Disposal ConsiderationsWaste Handling and Disposal Waste must be disposed of in accordance with federal, state and localenvironmental control regulations.Section 14- Transport InformationAirProper shipping name Not applicableUN/ID Number Not applicableIATA-DGR Class Not controlled under IATA.Packing Group Not applicableSection 15- Regulatory InformationEU RegulationsHazard Symbol(s) C; N; TRisk Phrases R28- Very toxic if swallowed. R32- Contact with acids liberates very toxic gas.R36/37/38- Irritating to eyes, respiratory system and skin. R50/53- Very toxic toaquatic organisms, may cause long-term adverse effects in the aquatic environment. Safety Phrases S26- In case of contact with eyes, rinse immediately with plenty of water and seekmedical advice. S28.1- After contact with skin, wash immediately with plenty ofwater. S36- Wear suitable protective clothing. S45- In case of accident or if you feelunwell, seek medical advice immediately (show the label where possible). S60- Thismaterial and its container must be disposed of as hazardous waste. S61- Avoidrelease to the environment.Refer to special instructions/Safety data sheets.U.S. Federal RegulationsHaz-Com Standard CLASS: Highly toxic.CLASS: Target organ effects.EPA TSCA 8(b) inventory: Sodium AzideTSCA 8(d) H and S data reporting: Sodium AzideSARA 313 toxic chemical notification and release reporting:Sodium Azide 50%available.State NotCanadian RegulationsWHMIS CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC). CEPA No products were found.Provincial No products were found.Section 16- Other InformationGenScript corporation MSDS is believed to be correct but only used as a guide for experienced personnel, GenScript shall not be held liable for any damage resulting from the handling or from contact with the above product.。
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Product Name:
A-317491 sodium salt hydrate
CAS No.:
Product Data Sheet
Cat. No.:
HY-15568A MWt:
606.57Formula:
C33H29NNaO9+Purity :>98%Solubility:Mechanisms:
Biological Activity:
Pathways:Membrane Transporter/Ion Channel; Target:P2X Receptor water >50 mg/ml
g y A-317491 is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux
mediated by the receptors.
IC50 value:
Target: P2X2/3 receptor It is known that P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Studies indicate that the P2X3 receptor is implicated in both neuropathic and
inflammatory pain. P2X3 receptor is a promising target for therapeutic intervention in cancer patients for pain management.References:
[1]. Hansen RR, Nasser A, Falk S, et al. Chronic administration of the selective P2X3, P2X2/3receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice. Eur J
Pharmacol. 2012 Aug 5;688(1-3):27-34.[2]. Wu JX, Xu MY, Miao XR, et al. Functional up-regulation of P2X3 receptors in dorsal root p g
[]p g p
ganglion in a rat model of bone cancer pain. Eur J Pain. 2012;16(10):1378-88.[3]. Xu J, Chu KL, Brederson JD, et al. Spontaneous firing and evoked responses of spinal
nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats. J
Neurosci Res. 2012;90(8):1597-606.[4]. Yasuda M, Shinoda M, Kiyomoto M, et al. P2X3 receptor mediates ectopic mechanical allodynia
with inflamed lower lip in mice. Neurosci Lett. 2012 18;528(1):67-72.[5]. Maria Cláudia G. Oliveiraa, Adriana Pelegrini-da-Silvaa, et al. Peripheral m...
Caution: Not fully tested. For research purposes only
Medchemexpress LLC。