重组生产胶原蛋白的研究进展解析
- 1、下载文档前请自行甄别文档内容的完整性，平台不提供额外的编辑、内容补充、找答案等附加服务。
- 2、"仅部分预览"的文档,不可在线预览部分如存在完整性等问题,可反馈申请退款(可完整预览的文档不适用该条件!)。
- 3、如文档侵犯您的权益，请联系客服反馈,我们会尽快为您处理(人工客服工作时间：9:00-18:30)。
重组生产胶原蛋白的研究进展
[27]John D C,Watson R, Kind A J, et al.Expression of an engineered form ofrecombinant procollagen in mouse milk[J].Nat. Biotechnol. 1999(17):385– 389. [28]Toman P D, Pieper F, Sakai N,et al.Production of recombinant human type I procollagenhomotrimer in the mammary gland of transgenic mice[J].Transgenic Res. 1999(8):415–427. [29]Tomita M, Munetsuna H, Sato T, et al.Transgenic silkworms produce recombinanthuman typeIII procollagen in cocoons[J].Nat. Biotechnol. 2003(21);52– 56. [30]Keizer-Gunnink I, Vuorela A, Myllyharju J, et al.Accumulation of properly foldedhuman type III procollagen molecules in specific intracellular membranouscompartments in the yeast Pichia pastoris[J]. Matrix Biol. 2000(19):29–36. [31]Prockop D J, Sieron A L, Li S W.Procollagen N-proteinase and procollagenC-proteinase. Two unusual metalloproteinases that are essential for collagenprocessing probably have two important roles in development and cell
signaling[J].MatrixBiol. 1998(16):399– 408. [32]Wegner G H.Emerging applications of the methylotrophic
yeasts[J].FEMSMicrobiol.Rev.1990(7): 279– 283. [33]Chung E, Miller E J.Collagen polymorphism: characterization of molecules withthe chain composition [a1(III)3] in human tissues[J].Science 1974(183):1200–1201. [34]Richter L J, Thanavala Y, Arntzen C J, et al.Production of hepatitis B surfaceantigen in transgenic plants for oral immunization[J].Nat. Biotechnol. 2000(18):1167–1171. [35]Lamport D T A.The isolation and partial characterization of hydroxyproline-richglycopeptides obtained by enzymic degradation of primary cell walls[J].Biochemist.1969(8):1155–1163. [36]Tanaka M, Sato K, Uchida T. Plant prolyl hydroxylase recognizes poly(L-proline)II helix[J].J. Biol. Chem. 1981(256):11397– 11400. [37]Hieta R, Myllyharju
J.Cloning and characterization of a low molecular weightprolyl 4-hydroxylase from Arabidopsis thaliana. Effective hydroxylationof proline-rich, collagenlike, and hypoxia-inducible transcription factora-like peptides[J].J. Biol. Chem. 2002(277):23965– 23971.