MILLIPORE纯水系统说明书
MilliporeSigma Milli-Q CLX 7000系列连接水纯化系统用户说明书
®7000 SeriesRobust & Reliable Performancefor Maximum Lab ProductivityYour biomedical laboratory is a busy and demanding environment, with clinical analyzers capable of processing several thousand samples per day. As water is the most frequently used fluidic reagent onboard an analyzer, your choice of water purification system is key to smooth and uninterrupted daily lab operations.The water purification solution must reliably provide your clinical analyzer(s) with consistent water quality that meets CLRW standards of the CLSI®. With the high-throughput Milli-Q® CLX 7000 analyzer feed series, your clinical laboratory benefits from a high-performance and economical water purification solution that fulfills its many critical needs:3Simply log into the MyMilli-Q™ web interface todiscover MyMilli-Q™ Remote Care , our online service and monitoring capability designed to support you in maximizing uptime. This unique service gives you and our support teams access to your Milli-Q ® CLX 7000 system and its data, for quick and precise remote diagnostics as well as repairs. Learn more about thisnew service capability on pages 8 and 9 of this brochure. And because every lab situation is different, our Milli-Q ® Services offering can be customized around your needs:• Before installation, a certified Field Service Engineer will analyze your feed water quality to provide the optimal parameter configuration for your system. This maximizes the performance and reliability of your Milli-Q ® CLX 7000 instrument and associated clinical analyzers.• Choose the Milli-Q ® Service Plan that’s right for your lab—from a single annual Preventive Maintenance Visit with replacement of aging parts, to full system coverage. • Online Contract Management lets you moreefficiently track your water system’s service history and easily schedule maintenance visits.• A range of options lets you customize your service solution. Choices include qualification, calibration and verification services, scheduled consumables shipments, and sanitization.Best-in-class Milli-Q ®Services,now supported by MyMilli-Q™ Remote CareBecause the reliability of biomedical laboratories is critical to patients and doctors alike, we offer an unprecedented level of service with the Milli-Q ® CLX 7000 Series.Trust in Pure Experience & ExpertiseWe are a partner you can count on. As one of the top three R&D investors in the Life Science Toolsindustry, we have a long history of strong partnerships with both biomedical laboratories and major clinical analyzer manufacturers. This valuable experience has enabled us to develop our expertise concerning end-user applications, such as biology, biochemistry, microbiology and immunology, and to design top-quality water purification solutions dedicated to feeding clinical analyzers.The Milli-Q ® CLX 7000 Series is manufactured in an ISO ® 9001- and ISO ® 14001-registered site. Additionally, to ensure efficiency and safety ofoperation, systems are CE-, cULus-, and FCC-certified. Furthermore, to reduce environmental impact, the Milli-Q ® CLX 7000 Series follows European Restriction of Hazardous Substances (RoHS) and Waste Electricaland Electronic Equipment (WEEE) directives.Contact your local Merck office for information about the service offer available for your facility, or visit /milli-qservices4® technology purification stepsElix ® module: Our unique technology is based on anion-permeable and cation-permeable membranes and high-quality, ion-exchange resin.Water produced by the Elix ® module enters the reservoir with resistivity greater than 5 MΩ·cm @ 25 °C (typically up to 15 MΩ·cm @ 25 °C).*The Milli-Q ® CLX 7000 Series relies on complementary water purification techniques, including state-of-the-art Elix ® electrodeionization (EDI) technology, to ensure production of consistently high quality water meets CLRW standards – at low and predictable running costs.In the Milli-Q ® CLX 7000 Series, potable tap water is first treated with a Progard ® pack and purified by reverse osmosis (RO) to remove up to 99% of contaminants. The resulting RO permeate water then enters the Elix ®Bacteria and their by-products interfere with chemistry assays and enzyme immunoassays, typically leading to unstable analyzer calibrations, high absorbance of blanks, reference drifts, and errors on mean patient values.In the Milli-Q ® CLX 7000 Series, UV lamp sanitization occurs at three stages:• During water production , a 254 nm bactericidal UV lamp inactivates bacteria.• In the tank , a UV lamp (ASM, Automatic Sanitization Module) regularly irradiates stored water and the tank walls, preventing bacterial growth and the formation of biofilm.* When CO dissolved in feed water is less than 30 ppm.5Optimize water consumption with an environmentally responsible system containing E.R.A.® technologyMilli-RX™ system(1992)Elix system (2003) with RO recovery loop Today’s Mili-Q CLX 7000Series system with E.R.A. technology10000m 900080007000600050004000300020001000WASTE (m )CLRW (m )Over the last 25 years, we have dramatically reduced water purification system water consumption, enabling laboratories to save up toseveral thousand dollars per year on tap water expenses . The graph shows water consumption and the split between CLRW produced and reject water for three of our water purification systems over a seven-year period (production of 1000 L/day of CLRW-quality water, 312 days per year).The Milli-Q ® CLX 7000 Series incorporates our E.R.A.® (Evolutive Reject Adjustment) technology — providing users with even greater savings.With its innovative and efficient reverse osmosis (RO) recovery loop, the Milli-Q ® CLX 7000 Series optimizes water consumption by recycling part of the waterrejected to the drain, thus reducing water waste and also extending RO cartridge and Progard ® pack lifetimes.Furthermore, depending on the feed water qualityanalysis, the Milli-Q ® CLX 7000 Series will calculate the best water recovery and will automatically optimize water consumption by means of motorized valves.No matter what the feed water temperature, inlet pressure, or conductivity may be, E.R.A.®technology’s automated valves ensure that the Milli-Q ® CLX 7000 Series flow rate and water recovery remain constant.* Users no longer need to manually adjust valves to maintain production flow rate and protect RO cartridge lifetime.These latest RO technologies illustrate our dedication to developing environmentally responsible waterpurification solutions to reduce tap water and system consumables use. The solutions reduce maintenance time, as well as the risk of human error — letting users save money on system operation, and also enjoy peace of mind with higher reliability, and optimized water purification system/analyzer uptime.* Please refer to Feed Water Requirements in the Specifications Table.6User-friendly system interface with all relevant information at a glanceWith its large, innovative touchscreen, the system is designed for intuitive operation, with all information available at a glance in a dashboard format. Nine different languages are available for greater convenience. Navigating and interacting with your water purification system has never been easier!... where a wizard will guide you through the maintenance procedure with easy, step-by-step instructions. You don’t need to be an expert to perform regular maintenance on your system!Clear, visible status of all consumables Notification zone for alerts and alarmsLarge display shows water qualities and storage volumeSystem status zone7An easy-to-use,low-maintenance systemA mobile, customizable systemLow maintenance saves time and increases profitability• Robust and patented Elix ® technology ensuresconsistent pure water, as well as low and predictable running costs – regardless of your feed water quality.* No maintenance is required for the Elix ® module.• An ergonomic and patented pack-locking system lets you change packs easily and quickly.• RFID technology prevents insertion of an incorrect purification cartridge in Milli-Q ® CLX 7000 systems, and also ensures automatic traceability of pack use and replacement, saving time for the user.• Automatic self-maintenance functions significantly reduce tap water use and increase cartridge lifetime: –The Progard ® pretreatment pack incorporatesseveral purification media in just one consumable to protect the RO membrane from particles, free chlorine, and scaling. Maintenance is easier and quicker with only one pack to change! –The system’s flush mode and cleaning cycles keep the RO membrane in top operating condition.Never before has it been so easy—or so time-saving—to use and maintain your water purificationsystem.Optimal use of lab spaceThe Milli-Q ® CLX 7000 Series is compact, quiet, and mounted on wheels with brakes, so it can be placed wherever it’s convenient — and moved to another location as the lab configuration grows or evolves.Customizable systems to fit your specific requirementsA number of options and accessories are available for the Milli-Q ® CLX 7000 Series to fit your specific requirements and to improve water quality monitoring:• An online TOC (Total OrganicCarbon) monitor allows verification that the TOC level of system water is below 500 ppb as required for CLRW quality. This avoids the need for duplicate assays or repeated analyzer calibrations. • Degassing option provides asolution for feed water that is highly contaminated with gases, such as a CO 2 concentration above 30 ppm.• RO regeneration tool , for use whenfeed water quality is poor, provides additional RO membrane cleaning, and completes the action of the Progard ® Autoclean pack.• Sanitary sampling valve for safe and reliable water sampling for microbiological analysis.• Water sensor(s) and alarm output(s) also can be easily added to your Milli-Q ®CLX 7000 system.* P lease refer to Feed Water Requirements in the Specifications Table.An ergonomic and patented pack-locking system.245 13 67What can MyMilli-Q™ Remote Care help you to achieve?• Assure productivity 24/7. Access real-time system information, water quality data and much more from anywhere at any time for 24/7 confidence in your lab’s performance.• Save time. In the event you need support, your interaction with Milli-Q® Services is streamlinedas MyMilli-Q™ Remote Care provides our service organization a secure and direct view of your system information. Our service teams can remotely diagnose and potentially repair your system, avoiding the need to wait for a service visit.• Maximize uptime. Receive notification of alertsand alarms (by email or SMS) allowing you to promptly and remotely manage your system, either independently or with our remote assistance.• Easier data traceability & accreditation. Audit preparation and lab accreditation have never been so effortless as data are automatically saved and can be easily accessed, searched and retrieved. Choose to download a standard Quality Report, or to create your own tailored reports.Connect to Peace of Mind Milli-Q® Services presents MyMilli-Q™ Remote Care, an onlineservice that simplifies the management of your Milli-Q® CLX7000 water purification system.1 Quickly view all system details.2E asily share water quality and system information with your analyzer supplier’sservice hotline.† CAP , College of American Pathologists9A water purification system that facilitates accreditation.Water used to feed an analyzer is a critical reagent. Its quality must be documented forbiomedical laboratories seeking accreditation (or reaccreditation) to the ISO 15189:2012 standard supported by CAP † 15189SM accreditation.To facilitate compliance with worldwide regulatory organization guidelines, Milli-Q ® CLX 7000 systems allow for full monitoring capabilities as well as automatic e-record archiving both:• Directly in the system — data are retrievable by USB key or via your lab’s intranet connection.• In the cloud when MyMilli-Q™ Remote Care is activated.E-record archiving supports traceability of all water-related daily operations, measurements and events. It saves time and is less expensive to manage versus paper documentation, as it removes the need for daily checks of the water purification system, hand-recording of parameters in a lab book, and physically archiving years of paper data.Now, with the user-friendly MyMilli-Q™ web interface and MyMilli-Q™ Remote Care service capability, data management is even moresimplified. Your system and water data are readily accessible and rapidly searchable, graphable and reportable — from anywhere at any time.An interactive Event Traceability tool lets you view events by type and over the timeline you specify. View past events (alarms, alerts, consumable replacements, service visits, custom events) and plan for future systemmaintenance. Click on any event and its details are displayed in the blue banner above the timeline. In this example, aProgard ® cartridge was replacedby J.SMITH on Aug 19, 2019.Water quality parameters (resistivity, temperature, TOC) are graphed over the timeline of your choice and can be easily downloaded.The system automatically stores a fully traceable—and easily retrievable—record of service history. In addition to archiving data, MyMilli-Q™ online tool lets you streamline contract management. You’ll be able to schedule maintenance visits, manage consumable deliveries and renew your service contracts, all online.Milli-Q® CLX 7000 Series Water Purification Process1. Inlet Valve2. Progard® Pretreatment Pack3. Conductivity Cell4. RO Pump5. Pressure Sensor6. RO Cartridge7. Twin Motorized Valve –RO Recirculation 8. RO Recirculation Loop9. Temperature Sensor10. Flow Sensor11. 3-Way AutomaticRinsing Valve12. Elix® Module13. Resistivity Cell14. UV Lamp (254 nm)15. Vent Filter16. Sanitary Overflow Sensor17. Automatic SanitizationModule (ASM)18. Distribution Pump19. Emergency Back Up –Quick Connector20. Q-Gard® Polishing Pack21. Opticap® Filter (0.22 μm)22. Sampling Valve23. Automatic Loop Rinsing Valve24. Back Pressure Regulator25. Recirculation Loop Valve26. TOC Monitor (Option)27. Degassing Unit (Option)Milli-Q® CLX 7000 Series SpecificationsThe Clinical Laboratory Reagent Water (CLRW) Quality Standard, defined by the CLSI®Resistivity> 10 MΩ.cm @ 25 °C Total organic carbon (TOC)< 500 ppbBacteria< 10 CFU/mL Filtration0.22 μmMilli-Q® CLX 7000 Series PerformanceMilli-Q® CLX 7040Milli-Q® CLX 7080Milli-Q® CLX 7120Milli-Q® CLX 7150 Make-up flow rate to reservoir*40 L/h (10.6 gal/h)80 L/h (21.1 gal/h)120 L/h (31.7 gal/h)150 L/h (39.6 gal/h) Make-up resistivity> 5 MΩ.cm @ 25 °C (10-15 MΩ.cm @ 25 °C typically)Built-in reservoir volume (net volume)90 L90 L140 L140 LDistribution flow rate to analyzers 4 L/minDistribution pressure to analyzers Adjustable: 0.9 up to 2.1 bar†Water Quality Distributed to AnalyzersResistivity> 15 MΩ.cm @ 25 °C Total organic carbon (TOC)Typically < 30 ppb Bacteria Typically < 1 CFU/mL Dissolved silica< 0.05 mg/L* Nominal flow rates ± 10% between 10 and 35 °C. Additional deviation of -3% per °C from 10 °C to 5 °C.† With a distribution loop length of 20 m.Technical Appendix10*Subject to subscription. Please contact your local Merck office for information about the service offer available for your facility.Dimensions and WeightsDimensions (H x W x D)1255 x 543 x 797 mm(49.4 x 21.4 x 31.4 in)1255 x 543 x 797 mm(49.4 x 21.4 x 31.4 in)1255 x 543 x 947 mm(49.4 x 21.4 x 37.3 in)1255 x 543 x 947 mm(49.4 x 21.4 x 37.3 in)Net weight (shipping box)134 kg (295.4 lb)143 kg (315.3 lb)155 kg (341.7 lb)167 kg (368.2 lb) Operating weight222 kg (489.4 lb)234 kg (515.9 lb)303 kg (668 lb)318 kg (701.1 lb)Feed Water RequirementsPressure 2 – 6 barFlow rate> 10 L/min at 2 barTap water connection¾ in. Gaz MFeed water type PotableTemperature 5 – 35 °CConductivity10 – 2000 μS/cm at 25 °C pH 4 – 10Total hardness (as CaCO3)< 300 ppmCO2< 30 ppmSilica< 30 ppmMerck KGaAFrankfurter Strasse 25064293 Darmstadt, Germany /labwater。
Milli-Q Synthesis 超纯水系统 中文使用说明书
Milli-Q Synthesis 超纯水系统中文使用说明书Milli-Q Synthesis超强组合型详细说明：IVF等极为困难的特殊培养以及分子生物学实验专用Milli-Q Synthesis系结合Gradient所采用的短波UV灯(185nm)以及Biocel所采用的5,000分子量的UF 膜，其产水的TOC值可在5ppb以下(当进水的TOC值低于50ppb)，热源则低于0.001EU/ml的新型超纯水装置。
本系统特别适用在容易受到水质影响的IVF或是DNA、RNA等分子生物学实验。
当然，Milli-Q Synthesis 的产水也可使用在需高灵敏度的HPLC检测上。
功能◆TOC数值显示◆电阻率显示◆水温显示◆纯水柱更换显示◆“A10”UV灯更换显示◆UV灯更换提示◆UF膜自动清洗◆消毒提醒◆定期循环◆定量取水◆取水纯度设定◆运转状态输出需加装“A10”TOC检测仪技术指标产水量 1.5L/min电阻率18.2MΩ·cm(25℃)总有机碳TOC 〈5ppb热源0.001EU/mL细菌〈1cfu/mL颗粒〉0.22um 〈1P/mLElix产水作为进水，其TOC值低于50ppbMillipore公司是驰名世界的纯水及超纯水设备制造商，根据用户的独特要求设计制造出一系列不同的纯水及超纯水系统。
其中Milli-Q系列更是所有从事化学分析、生化研究及细胞培养所不可缺少的，该系统以反渗透水、蒸馏水、Elix水或去离子水为进水，随时提供符合美国材料试验学会(ASTM)、美国病理学会(CAP)和临床医学会(NCCLS)规定的I级(试剂级)超纯水。
a)纯化系统将自来水作初步处理，一般包括预过滤（深层过滤及膜过滤）和反渗透或蒸馏法，而反渗透因其污染物去除率达到90%-95%以上，回收率达20%-40%以上，效益比传统纯蒸馏法更理想，因此是Milli-Q超纯水系统的理想进水。
另外，Millipore为配合日渐普及的微量分析，研制出Elix连续电流去离子系统，结合反渗透及连续电流去离子技术的优点——经济高效(R〉5MΩ·cm)，可用于一般实验室作分析用水，又因其出水质量高，如作为Milli-Q的进水，更能提高Milli-Q纯化柱的使用寿命及出水水质。
Millipore超纯水制造系统操作及保养手册
範例: 針對共同項目
M ILLI-Q Ac. Gr. Bio.Syn.A10
: 所有線條皆為柱狀。 （表示本功能是用在所有四種機型）
針對特殊系統: Gradient 所有圖形皆收錄在手冊最後之摺頁內。
系統各部分圖形 - 詳列於手冊之後
如何使用本手冊
本手冊是說明如何安裝耗材，使用及保養您的Milli-Q純水系統，雖然Milli-Q系統非常容易使用，但還 是強烈建議使用者徹底閱讀本手冊，可防止系統故障，可使使用者更熟悉所有功能及操作指令。
如何區分不同 Milli-Q 機型所涵蓋之不同應用內容
本操作手冊使用下述表記來區分。
如何使用本手冊 ......................................................................................................................................... 4 如何區分不同機型所針對的應用內容...................................................................................................... 4 警告標誌之意義.......................................................................................................................................... 4 前言 ............................................................................................................................................................. 5 一般說明...................................................................................................................................................... 5 系統運作原理.............................................................................................................................................. 5 系統結構流程圖.......................................................................................................................................... 6 規範.............................................................................................................................................................. 7 裝置 ............................................................................................................................................................. 9 系統裝置...................................................................................................................................................... 9 裝置方法.................................................................................................................................................... 10 MILLI-Q 系統操作 .................................................................................................................................. 13 操作的幾種模式........................................................................................................................................ 13 標準顯示.................................................................................................................................................... 13 附加顯示.................................................................................................................................................... 14 按鍵使用方法............................................................................................................................................ 15 MILLI-Q 系統啟動 ..................................................................................................................................... 20 保養 ........................................................................................................................................................... 21 例行保養時間表........................................................................................................................................ 21 例行保養.................................................................................................................................................... 22 疑難排除 ................................................................................................................................................... 25 疑難排除、訊息........................................................................................................................................ 25 警告號碼表................................................................................................................................................ 27
Milli-Q_Adv超纯水机使用说明书(中文)
版本 0, 11/06
商标 Millipore，A10， Elix，Q-Gard，Milli-Q，Millipak 和 Milli-RO 为 Millipore 公司的注册商标。 BioPak，Quantum，Milli-RX， RiOs 和 Q-POD 为 Millipore 公司的商标。 所有其他商标均为各自制造商的商标。
第 2 章 产品信息 ...................................................................................................2
2-1 MILLI-Q® 超纯水系统概述 .....................................................................................................................2 2-2 MILLI-Q 产水规格..................................................................................................................................4 2-3 系统流程图 ...........................................................................................................................................4 2-4 技术规格...............................................................................................................................................7
MilliporeSigma HX 7000 SD All-in-One 水纯度设备说明书
Key features and benefits include:With a Milli-Q ® HX 7040/7080/7120/7150 SD system, you can count on a robust water purification solution that is designed to meet your laboratory’s current and future requirements.Complete, Compact, connected & CustomizableYour Pure Water Solution for up to 3000 L/day2The Milli-Q ® HX 7000 SD series represents a modern range of high-throughput water purification systems. These systems provide a complete, compact, connectedand fully-customizable pure water solution for large laboratories requiring a few hundred to up to 3000 L per day of Type 2 pure water.3• Equipment and instruments including dishwashers, autoclaves, clinical analyzers, heating baths, and environmental and humidity chambers• Taps on benches for general glassware rinsing and buffer and media preparation • Point-of-use polishers and purifications systems to obtain ultrapure waterReliably feed all your pure water needs®DispenserMilli-Q ®IQ 7000Trust in Pure ExperienceFor over 50 years, we have been the partner of choice for water purification systems and services for labscientists who need to assure the quality and reliability of results.We provide a comprehensive range of water purification systems to fit your needs, laboratory space, building configuration, and budget.• Customized solutions • Valuable advice• Comprehensive maintenance • Qualification programs • Budget planning• Remote service capabilitiesFrom conception, design and installation, through to engineering expertise and technical support services, our specialists in pure water solutions can work with you through any project for full peace of mind.PurificationA Complete Pure Water SolutionCover the full spectrum of your pure water needs. Milli-Q® HX 7000 SD systems contain an optimized sequence of state-of-the-art purification technologies, an integrated 140 L storage reservoir and distribution pump, plus remote monitoring and control capabilities.Pretreatment is tailored to yourfeed water quality.• Progard® cartridges remove particles (0.5 μm filter), free chlorine and colloids (activated carbon filter)• Anti-scaling agent protects the RO membrane from hard water• Bactericidal carbon prevents bacterial growth• Backwashing carbon filters and ultrafiltration can be added if high fouling index and/or high chlorine levels Advanced RO & patented E.R.A.® technologies yield constant flow rates while reducing water consumption and associated costs.• Advanced RO (reverse osmosis) removes 95-99% of ions, and 99% of all dissolved organics(MW >200 Da), microorganisms and particles.• E.R.A.® (Evolutive Reject Adjustment) technology takes into account feed water quality (conductivity, temperature, hardness, alkalinity, CO2) to automatically optimize water recovery (between 45% and 75%) and reduce water consumption by up to 50% compared to other RO systems of similar throughput.• Achieve constant flow and waterrecovery rates, regardless of feedwater temperature• Eliminate manual valveadjustments due to temperaturefluctuations• Reduce maintenance time andthe risk of human error• Increase RO cartridge lifetime,reducing consumables waste• Optimize your system’s uptimeand reliabilityOur patented E.R.A.® technology saves you water, time and money. 4® technology purification steps• Our patented Elix ® electrodeionization (EDI) module removes remaining ions to produce constant-quality pure water, regardless of feed water quality (conductivity, CO 2 levels) or RO cartridge performance• The module continuously self-regenerates its ion exchange resins via a small electrical field • Eliminates the need for:–Hazardous chemical regeneration procedures –Replacement of costly resins –Changing DI cartridges –Adding softeners• This reduces maintenance time and ensures low and predictable running costsUV lamps provide full bacterial control.The new Milli-Q ® HX 7000 SD series is designed to maintain the best water quality at each step in the pure water process.• During water production, a built-in 254 nm bactericidal UV lamp inactivates bacteria andreduces the need for frequent system sanitization.• Within the distribution loop, a UV lamp (option) irradiates circulating water before feeding out to instruments and equipment, or returning to the reservoir.As a result, the water’s bacterial count is reduced by a log of 4†, making it well-suited for bacteria-sensitive applications.Elix ® module: Our unique EDI technology is based on anion-permeable and cation-permeable membranes and high-quality ion-exchange resin. Water produced by the Elix ® module enters the reservoir with resistivity greater than 5 MΩ·cm @ 25 °C (typically up to 15 MΩ·cm @ 25 °C)*.*When CO 2 dissolved in feed water is less than 30 ppm.†E.g., In a well-designed and maintained distribution loop, a bacterial count of10,000 cfu/mL is reduced to 1 cfu/mL, irrespective of the system’s nominal flow rate.The Elix ® EDI module produces consistently high-quality pure water with no maintenance and at low and predictable running costs.5Purification6Pure water produced by the Milli-Q ® HX 7000 SD system meets or exceeds water quality levels described by the following organizations:European Pharmacopoeia Purified water United States Pharmacopeia Purified Water Japanese Pharmacopoeia Purified Water Chinese Pharmacopoeia Purified Water ISO ® 3696Grade 2 Water ASTM ® D1193Type II Water JIS K 0557A3 Water Chinese National Standard GB/T 6682Level 2 WaterThe Compliance Report on Milli-Q ®HX 7000 SD Series conformity to industry norms is available upon request.Minimum specifications for different water types*Organics TOC (ppb)< 200< 50< 10Pyrogens EU/mLNA NA < 0.03Particulates Particulates > 0.2 µm (units/mL)NA NA < 1Colloids Silica (ppb)< 1000< 100< 10BacteriaBacteria (cfu/mL)< 1000< 100< 1*These values are provided only as guidelines, as some specific laboratory applications may require a quality superior to the quality indicated by the norms.In an optimalconfiguration that includes an Opticap ® filter, UV lamp and a well-designed and maintained loop,product water from the Milli-Q ® HX 7000 SD system meets or exceeds relevant standards and Pharmacopeia listed above at all points of use.Storage & Distribution 7Integrated ConvenienceMilli-Q ® HX 7000 SD systems are complete with an integrated storage reservoir and distribution pump, for convenient and compact protection and circulation of your pure water.An integrated 140 L reservoir, made of high purity polyethylene, contains numerous critical designfeatures to reliably store and protect your pure water quality.• Vent filters protect again airborne contamination • Differential pressure sensors ensure accurate level sensing and prevent overflow • Hermetically sealed with no overflow to the drain prevents bacterial contamination • Automatic drain function helps with systemmaintenance and to refresh the reservoir water, ensuring high quality water even on low-use days • Sanitary sampling ports and connections provide safe and reliable water sampling and circulation to the accessory panelThe distribution pump provides a flow of up to20 L/min for a loop of up to 50 m long . This enables one Milli-Q ® HX 7000 SD system to reliably supply the pure water needs of a large laboratory or an entire floor of a building.Milli-Q ®HX 7000 SD system with distribution to a large lab or building floor.Q-POD ®dispenserOpticap ® final filtrationUVDishwasher direct feedEDS-Pak ® PolisherEnvironmental analysisBioPak ® PolisherRNase-free water, DNase-free water Buffer and Media Prep (Stem Cells)Millipak ® Filter Units HPLC, UHPLC, LC-MSBuffer and Media Prep (Microbiology)Milli-Q ® HX 7000 SD systemMilli-Q ® IQ 7000 systemAutoclaveLarge display shows waterqualities and distribution processClear, visible status of all consumablesSystem status zoneNotification zone for alertsand alarmsRemote Monitoring & ControlIntuitive OperationA superior communications interface facilitates navigation, data access and control.With its large interactive touchscreen, the system is designed for intuitive operation, with all information needed for daily operation available at a glance. Users can quickly navigate among several views to see data, including:• Production status • Storage levels • Dispensing status • System settings • Consumables status• Preventative alarms and alertsWhat can MyMilli-Q™ Remote Care help you to achieve?• Assure productivity 24/7. Access real-time systeminformation, water quality data and more fromanywhere at any time for 24/7 confidence in yourlab’s performance.• Save time. In the event you need support, yourinteraction with Milli-Q® Services is streamlinedas MyMilli-Q™ Remote Care provides our serviceorganization a secure and direct view of yoursystem information. Our service teams can remotelydiagnose and potentially repair your system, avoidingthe need to wait for a service visit.• Maximize uptime. Receive notification of alertsand alarms allowing you to promptly and remotelymanage your system, either independently or withour remote assistance.• Easier data traceability & accreditation. Auditpreparation and lab accreditation have never beenso effortless as data are automatically saved and canbe easily accessed, searched and retrieved. Chooseto download a standard Quality Report, or to createyour own tailored reports. Connectivity AssuresProductivityDiscover MyMilli-Q™ Remote Care — an online monitoring andservice capability that supports your lab’s maximum productivity.10MyMilli-Q™ Remote Care facilitates data traceability & eases accreditationWater is a reagent whose quality must bedocumented for laboratories seeking accreditation (or reaccreditation) to the ISO ® 15189:2012 standard.To facilitate compliance with worldwide regulatory organization guidelines, Milli-Q ® HX 7000 SDsystems allow for full monitoring capabilities as well as automatic e-record archiving both:• Directly in the system — data are retrievable by USB key or via your lab’s intranet connection.• In the cloud when MyMilli-Q™ Remote Care is activated.E-record archiving supports traceability of all water-related daily operations, measurements and events. It saves time and is less expensive to manage versus paper documentation, as it removes the need for daily checks of the water purification system, hand-recording of parameters in a lab book, and physically archiving years of paper data.With the user-friendly MyMilli-Q™ web interface and MyMilli-Q™ Remote Care service feature, data management is greatly simplified. Yoursystem and water data are readily accessible and rapidly searchable, graphable and reportable — from anywhere at any time.An interactive Event Traceability tool lets you view events by type and over the timeline you specify. View past events (alarms,alerts, consumable replacements,service visits, custom events)and plan for future system maintenance. Click on any event and its details are displayed in the blue banner above the timeline. In this example, a Progard ® cartridge was replaced by J.SMITH on Aug 19, 2019.The system automatically stores a fully traceable—and easily retrievable—record of service history. In addition to archiving data, MyMilli-Q™ online tool lets you streamline contract management. You’ll be able to schedule maintenance visits,manage consumable deliveries and renew your servicecontracts, all online.Water quality parameters (resistivity, temperature,TOC) are graphed over the timeline of your choice andcan be easily downloaded.11Customizable to fit your requirementsThe Milli-Q ® HX 7000 SD series is modular, allowing you to select just the options and accessories you need to meet your specific requirements and to improve water quality monitoring.The resistivity booster may be easily installed on the front of the Milli-Q ® HX 7000 SD system. Our ergonomic and patented pack-locking mechanism allows for rapid replacement when needed.The loop panel with Opticap ® filter and UV lamp, may be wall-mounted or stand-alone.Passion to Drive Your Performance Best-in-class Milli-Q® Services,now supported by MyMilli-Q™ Remote CareAt each stage of your project (conception, design and installation) to everyday use, we offer comprehensive, high quality support services that can be customized to meet your needs.• Before installation, a certified field service engineer analyzes your feed water quality.• During installation, feed water parameters are programmed into system memory to optimize water recovery and maximize system performance.• Throughout system lifetime, apply the Milli-Q®Service Plan that meets your lab’s needs, froma single annual Preventive Maintenance Visit with replacement of aging parts, to full system coverage.• Choose from a range of additional options, including qualification, calibration and verification services, scheduled consumables shipments, and sanitization.Our Milli-Q® certified field service engineers can provide:• Operator training• Technical and maintenance support• Preventive maintenance• Customized services, such as conductivity and temperature meter verification• Assistance to help you successfully performthe Installation Qualification (IQ), Operational Qualification (OQ) and maintenance program within a cGMP and/or GLP environment/milli-qservicesLog into MyMilli-Q TM online solution to streamline the care of your Milli-Q® system fleet:• Track service history & reports• Plan maintenance visits• Manage consumable deliveries• Renew service contracts• Remotely monitor, control & service your system (via the MyMilli-Q™ Remote Care feature, see pages 9-10)1213Technical AppendixMilli-Q ® HX 7000 SD seriesMilli-Q ® HX 7000 SD SeriesPanel Options===MM23334567891010101112141311718192023151621282730313229222124252421252621System DimensionsType 2 Water Purification Systems*Vent filter TANKVNT01: + 48 mmFlow Schematic of Purification Process1. Inlet valve2. Progard ® pretreatment pack3. Conductivity cell4. RO pump5. Pressure sensor6. RO cartridge7. Twin motorized valve - RO recirculation 8. RO circulation loop 9. Temperature sensor 10. Flow sensor11. 3-way automatic rinsing valve 12. Degassing unit (option)13. Elix ® module14. UV lamp (254 nm) 15. Feed by the bottom16. Tank level pressure sensors 17. Vent filter 18. 140 L tank 19. Overflow20. Return to the bottom 21. Valve22. Distribution pump23. UV lamp (254 nm; option)24. Sampling valve 25. Pressure gauge26. Opticap ® filter (0.22 μm; option)27. Automatic loop rinsing valve 28. Spring-loaded check valve 29. TOC monitor (option)30. Resistivity cell (option)31. Temperature cell (option)32. Resistivity booster (option)14Milli-Q ® HX 7000 SD Series PerformanceIn an optimal configuration that includes an Opticap ® filter, UV lamp and a well-designed and maintained loop, product water from the Milli-Q ® HX 7000 SD system meets or exceeds the relevant standards and Pharmacopeia listed on page 6 of this brochure at all points of use.Typical water quality measures with a well-designed and maintained distribution loop of 20 meters:Resistivity (@25 °C)> 1 MΩ.cm 10-15 MΩ.cm > 1 MΩ.cm > 1 MΩ.cm Conductivity (@25 °C)< 1 µS/cm 0.07-0.1 µS/cm < 1 µS/cm < 1 µS/cm Total Organic Carbon (TOC)< 50 ppb < 50 ppb < 50 ppb < 50 ppb Bacteria count --≤ 10 cfu/mL ≤ 1 cfu/mL*Dissolved silica≤ 3 ppb≤ 3 ppb≤ 3 ppb≤ 3 ppb* Sampled after Opticap ® filter.Electrical SpecificationsSystem typeVoltage & frequency Power consumption (VA)Milli-Q ® HX 7040/7080 SD220-240 VAC @ 50/60 Hz 1000120 VAC @ 60 Hz 100 VAC @ 50/60 HzMilli-Q ® HX 7120/7150 SD220-240 VAC @ 50/60 Hz 1500120 VAC @ 60 Hz 100 VAC @ 50/60 HzThe source of electrical power must be earth grounded.General SpecificationsNoise level< 50 dB at 1 meterCommunication protocol TCP/IP/CGI, embedded web server and HTML 5 embedded website*Communication ports Ethernet, USB 2.0LanguagesEnglish, French, Spanish, Portuguese, Italian, German, Russian, Chinese, Japanese* No additional software needed for remote control.System type Make-up flow rate to reservoir*Dry weight Shipping weight Operating weight Milli-Q ® HX 7040 SD 40 L/h (10.6 gal/h)97 kg (214 lb)116 kg (256 lb)247 kg (545 lb)Milli-Q ® HX 7080 SD 80 L/h (21.1 gal/h)106 kg (234 lb)125 kg (276 lb)256 kg (567 lb)Milli-Q ® HX 7120 SD 120 L/h (31.7 gal/h)114 kg (251 lb)133 kg (293 lb)264 kg (582 lb)Milli-Q ® HX 7150 SD150 L/h (39.6 gal/h)126 kg (278 lb)145 kg (320 lb)276 kg (608 lb)* Nominal flow rates ± 10% between 10 and 35 °C. Additional deviation of -3% per °C from 10 °C to 5 °C.Feed Water RequirementsPressure 2 – 6 barFlow rate> 10 L/min at 2 bar Feed water type Potable water Temperature 5 – 35 °CConductivity 10 – 2000 µS/cm at 25 °C pH4 – 10Hardness (as CaCO 3)< 300 ppm Silica concentration< 30 ppm Carbon dioxide concentration (CO 2)< 30 ppm Langelier Saturation Index (LSI)< 0.3Fouling Index (FI 5) or Silt Density Index (SDI)≤ 7(*)Total Organic Carbon (TOC)< 1 ppm Free chlorine for Milli-Q ® HX 7040 (LC), 7080 (LC), 7120, 7150 SD systems < 1.5 ppmFree chlorine for Milli-Q ® HX 7040 (HC), 7080 (HC) SD systems ≥1.5 and < 3 ppm* < 12 when the optional UF pretreatment is installed.15Part numbers (accessories, consumables, options)ZUFPREUN8Installation kit for UF Pretreatment ZLXLPTCAB External Pretreatment-XL system cable ZLXLPTFSWFlow switch for pretreatment unit Storage & DistributionTank SpecificationsMaterialHigh purity polyethylene Built-in reservoir volume (net)140 L (37 gal)Distribution Pump Performance (Centrifugal)5 LPM / 1.32 GPM 2.2 bar / 32 psi 15 LPM / 3.96 GPM 1.9 bar / 28 psi 20 LPM / 5.28 GPM1.6 bar / 23 psiPlumbing ConnectionsInlet (feed water connection)3/4” BSPLoop start/return 1 1/2” Sanitary TC Drains3/8”Merck KGaAFrankfurter Strasse 25064293 Darmstadt, Germany/labwaterFor more information on Milli-Q® HX 7000 SD, please visit: /milli-q-hxsd。
MILLIPORE纯水及超纯水仪操作规程
MILLIPORE纯水及超纯水仪操作规程
一、检查上次使用记录
二、检查仪器附件是否齐全
三、操作
1、接通电源：打开开关，按下OPERATE/STANDBY键，使系统处于待机状态，此时power键指示灯亮。
2、按下取水键可使系统进入OPERATE（运转）状态并制水，系统经常保持在此状态。
正常的取水程序如下：
1、确认系统处在PRE-OPERATE状态，供水箱有水。
2、扳下取水开关（E）开始取水，此时系统会自动显示产水的电阻率值等参数。
3、取水完毕，推回取水开关，显示屏幕会回到PRE-OPERATE状态。
四、工作完毕，关闭电源，使恢复到工作前状态。
五、做好工作记录。
MilliporeSigma Synergy 水质纯化系统产品说明书
Synergy®Water Purification Systems Ultrapure water at your point of use - with easy and convenient dispense!The life science businessof Merck operates asMilliporeSigma in theU.S. and Canada.Water Purification Systems 123456897Ultrapure water at your point of use - with easy and convenient dispense!Synergy ® Systems Water Purification PathwayUltrapure water easily accessible wherever you need it in your lab With the Synergy ® range of water purification systems, you benefit from a choice of ultrapure water dispensing possibilities. The innovative, space-saving Remote dispenser offers you water delivery solutions to best fit the way you work, with easy and convenient remote delivery up to two meters away from your water production unit.Point-of-use system to supply ultrapure water Synergy ® water purification systems produce ultrapure water using feed water from an existing pretreated pure water supply (such as a RiOs™ system).Compact design for the most efficient use of your lab space A small footprint makes it easy to install the Synergy ® systems wherever you want to ― on or under the bench-integrated or on the wall.Flow rates adapted to your ultrapure water needsSystems in the Synergy ® range can dispense more than 1.5 L/min water .High quality water to meet the requirements of your most critical applicationsOptions such as a UV lamp and a range of Application Pak point-of-use polishers are available to fine-tune your ultrapure water.Easily accessible information on system operationThe user-friendly display provides system status at a glance; the concise Quick Reference Guide is a handy guide for daily operation.Simple, low-level self-maintenance SynergyPak ® purification cartridges enable easy and rapid replacement.1. Inlet Solenoid Valve2. Booster Pump3. Photooxidation UV lamp4. SynergyPak ® 1, 2 or 35. Product Resistivity Cell6. Point-of-Use (POU) Solenoid Valve7. Final Filter8. Recirculation Loop9. Check ValveChoose the solution that’s right for you Easy installationInstalling the Synergy® system is so easy you can do ityourself. Just connect the system to a pretreated watersupply (e.g., from a RiOs™ system), plug it in, andinsert the SynergyPak® purification cartridges. Then, ifyou have chosen the system with a Remote dispenser,follow the simple setup procedure ― and your systemis ready to use!Optimized lab spaceThe Synergy® system’s small footprint will allow you tofind a space for it anywhere in your laboratory, eitheron or under the benchtop, or wall-installed. You choosethe best location for your Synergy® system.High ultrapure flow rates to match yourrequirementsWith high flow rates above 1.5 L/min, the systemsprovide ultrapure water on demand in the volumesrequired to satisfy critical applications. When not inuse, your Synergy® system will recirculate water inorder to maintain water quality, so that you do nothave to wait when sourcing ultrapure water. For yourconvenience, and to save time, you can also set thesystem to automatically deliver your selected volume ofultrapure water on demand.The high quality ultrapure water produced by Synergy®systems is suitable for applications such as productionof mobile phase for chromatographic separations;preparation of blanks and standard solutions forspectrophotometry; spectroscopy or other analyticaltechniques; and preparation of buffers for biochemicaland molecular biology experiments.Fine-tune your water quality Point-of-use ultrapure waterFor laboratories with an existing access to pure water, Synergy® systems provide a solution to point-of-use ultrapure water needs. The high quality ultrapurewater produced by Synergy® systems is suitable for applications such as HPLC mobile phase preparationand sample dilution; buffer and cell culture media preparation; preparation of chemical solutions usedwith titrators, spectrophotometers, and electrophoresis systems.Organic-sensitive applicationsIf you work with organic-sensitive applications suchas HPLC, LC, GC or TOC analyses, the Synergy® UV system contains a built-in photooxidation UV lamp to reduce TOC to less than 5 ppb. Water with low TOC provides important benefits to HPLC users such ashigher sensitivity and longer column lifetime. The same UV lamp also destroys bacteria.Application Pak point-of-use polishersOur range of Application Pak polishers makes itpossible to fine-tune your ultrapure water quality to match your research. Are your applications sensitive to bacteria, particulates, pyrogens, nucleases, endocrine disruptors or volatile organic compounds? If so, just choose the appropriate final polisher from our range ofApplication Paks to provide optimal water quality foryour requirements.Please visit /labwaterfor more information.Stay focused on your work Versatile remote dispenserDesigned to fit perfectly into your lab environment, the versatile Remote dispenser can be placed up to two meters from your Synergy® water purification unit. Select the free-standing or wall-installed model according to your needs ― their ergonomy will make either one a welcome addition to your lab, giving you the freedom to focus on your research, while dispensing ultrapure water exactly where you need it. Alternatively, Synergy® systems are also available with an integrated dispenser for use on the benchtop.We offer more than waterJust the information you needThe intuitive color graphic display shows key system parameters at a glance, enabling easy water quality and maintenance warning monitoring; the screen rotates for easy viewing wherever the system is located. Additional information on system operation and maintenance is provided by the Quick Reference Guide and User Manual stored on the water production unit.User-friendly maintenanceThe SynergyPak® purification cartridges integrate all the main purification technologies. The Synergy® system will automatically tell you when it’s time to change the SynergyPak®, and“plug-and-use” design makes this easy to do in just a couple ofminutes!Milli-Q® Service PlansTo optimize the performance and lifetime of your water purification system, we offer a complete portfolio of service plans ranging from a single annual checkup to a full system cover. For more information, please check with your applications specialist or visit our website: /labwaterSpecificationsUltrapure (Type I) Product Water QualityResistivity18.2 MΩ·cm @ 25 °CInstant flow rate (with Application Pak final filter)> 1.5 L/minTOC (Synergy® system)< 10 ppbTOC (Synergy® UV system)< 5 ppbParticulates (size > 0.22 µm)1< 1 particulate/mLBacteria (Synergy® system)1< 0.1 cfu/mLBacteria (Synergy® UV system)1< 0.01 cfu/mLEndotoxin (pyrogens)2< 0.001 EU/mLRNases2< 0.01 ng/mLDNases2< 4 pg/µLThese values (validated with Elix feed water) are typical and may vary depending on the nature and concentration of contaminants in the feed water. With Millipak filter or with Biopak ultrafiltration cartridge as final polisherOnly with Biopak polisherFeed water for use with Synergy systems should be pretreated Type 2 (e.g. Elix, DI water) or Type 3 (e.g. RiOs™, distilled water) grade water delivered at 0.3 bar maximum pressure.System InformationDimensions (H x W x D)54 x 29 x 38 cm (21.3 x 11.4 x 15 in)Net weight (Synergy® system) 6.7 kg (14.8 lb)®。
Milli_PORE超纯水机使用说明书
Fax (02) 26.50.324
Roma:
Tel. (06) 52.03.600
Fax (06) 52.95.735
JAPAN
Tel. (03) 5442-9711
Fax (03) 5442-
9736 Life Sciences
9737 BioPharm.
9734 Lab Water
Fax +43 1 877-1654
Laboratory Water Division:
Tel. +33 1 30 12 7000
Fax +33 1 30 12 7180
FINLAND
Tel. (09) 804 5110
Fax (09) 256 5660
FRANCE
Tel. 01 30 12 7000
Fax 01923 818297
U.S.A.
Tel. (781) 533-6000
Fax (781) 533-3110
IN ALL OTHER COUNTRIES
Millipore Intertech (U.S.A.)
Tel. +1 (781) 533-8622
Fax +1 (781) 533-8630
微生物
1 CFU/ml
MILLI-Q
Milli-Q精製水水質可符合或超越ASTM試劑水規格之標準。
ASTM試劑水規格之標準如下表所列。Milli-Q Synthesis (或Milli-Q Synthesis A10)之水質規格如上所示。
(資料來源“Standard Specification for Reagent Water”(試劑水規格之標準)Designation: D 1193 – 99; American Society For Testing And Materials ASTM)