Nonlinear dynamic response and buckling of laminated cylindrical shells with axial shallow groov
杜克物理

ResearchAccelerator PhysicsTom Katsouleas: use of plasmas as novel particle accelerators and light sources Ying Wu: nonlinear dynamics of charged particle beams, coherent radiation sources, and the development of novel accelerators and light sourcesBiological PhysicsNick Buchler: Molecular mechanisms and the evolution of switches and oscillators in gene networks; systems biology; comparative genomicsGlenn Edwards: Interests include 1) the transduction of light to vibrations to heat and pressure in biological systems and 2) how biology harnesses physical mechanisms during pattern formation in early Drosophila development.Gleb Finkelstein: Electronic transport in carbon nanotubes and graphene; Inorganic nanostructures based on self-assembled DNA scaffolds.Henry Greenside: Theoretical neurobiology in collaboration with Dr. Richard Mooney's experimental group on birdsong.Calvin Howell: Measurement of the neutron-neutron scattering length, carbon and nitrogen accumulation and translocation in plants.Joshua Socolar: Organization and function of complex dynamical networks, especially biological networks, including electronic circuits and social interaction networksWarren Warren: novel pulsed techniques, using controlled radiation fields to alter dynamics; ultrafast laser spectroscopy or nuclear magnetic resonanceCondensed Matter PhysicsHarold Baranger: Theory of quantum phenomena at the nanometer scale;many-body effects in quantum dots and wires; conduction through single molecules; quantum computing; quantum phase transitionsRobert Behringer: Experiments on instabilities and pattern formation in fluids; flow, jamming, and stress patterns in granular materials.David Beratan: molecular underpinnings of energy harvesting and charge transport in biology; the mechanism of solar energy capture and conversion in man-made structuresShailesh Chandrasekharan: Theoretical studies of quantum phase transitions using quantum Monte Carlo methods; lattice QCDAlbert Chang: Experiments on quantum transport at low temperature;one-dimensional superconductivity; dilute magnetic semiconductor quantum dots; Hall probe scanning.Patrick Charbonneau: in- and out-of-equilibrium dynamical properties ofself-assembly. Important phenomena, such as colloidal microphase formation, protein aggregation.Stefano Curtarolo: Nanoscale/microscale computing systems & Quantum Information.Gleb Finkelstein: Experiments on quantum transport at low temperature; carbon nanotubes; Kondo effect; cryogenic scanning microscopy; self-assembled DNA templates.Jianfeng Lu: Mathematical analysis and algorithm development for problems from computational physics, theoretical chemistry, material sciences and others. Maiken H. Mikkelsen: Experiments in Nanophysics & Condensed Matter Physics Richard Palmer: Theoretical models of learning and memory in neural networks; glassy dynamics in random systems with frustrated interactions.Joshua Socolar: Theory of dynamics of complex networks; Modeling of gene regulatory networks; Structure formation in colloidal systems; Tiling theory and nonperiodic long-range order.David Smith: theory, simulation and characterization of unique electromagnetic structures, including photonic crystals and metamaterialsStephen Teitsworth: Experiments on nonlinear dynamics of currents in semiconductors.Weitao Yang: developing methods for quantum mechanical calculations of large systems and carrying out quantum mechanical simulations of biological systems and nanostructuresHigh Energy PhysicsAyana Arce: Searches for top quarks produced in massive particle decays, Jet substructure observable reconstruction, ATLAS detector simulation software frameworkAlfred T. Goshaw: Study of Nature's most massive particles, the W and Z bosons (carriers of the weak force) and the top quark.Ashutosh Kotwal: Experimental elementary particle physics; instrumentation, Precisely measure the mass of the W boson, which is sensitive to the quant um mechanical effects of new particles or forces.Mark Kruse: Higgs boson, production of vector boson pairs, andmodel-independent analysis techniques for new particle searches.Seog Oh: High mass di-lepton search, WW and WZ resonance search, A SUSY particle search, HEP detector R&DKate Scholberg: Experimental particle physics and particle astrophysics; neutrino physics with beam, atmospheric and supernova neutrinos (Super-K, T2K, LBNE, HALO, SNEWS)Chris Walter: Experimental Particle Physics, Neutrino Physics,Particle-Astrophysics, Unification and CP ViolationImaging and Medical PhysicsJames T. Dobbins III: advanced imaging applications to improve diagnostic accuracy in clinical imaging, scientific assessment of image quality, developing lower cost imaging for the developing worldBastian Driehuy: developing and applying hyperpolarized gases to enable fundamentally new applications in MRIAlan Johnson: engineering physics required to extend the resolution of MR imaging and in a broad range of applications in the basic sciencesEhsan Samei: design and utilization of advanced imaging techniques aimed to achieve optimum interpretive, quantitative, and molecular performanceWarren Warren: novel pulsed techniques, using controlled radiation fields to alter dynamics; ultrafast laser spectroscopy or nuclear magnetic resonanceNonlinear and Complex SystemsThe Center for Nonlinear and Complex Systems (CNCS) is an interdisciplinar y University-wide organization that fosters research and teaching of nonlinear dynamics, chaos, pattern formation and complex nonlinear systems with many degrees of freedom.Robert Behringer: Experiments on instabilities and pattern formation in fluids; flow, jamming, and stress patterns in granular materials.Patrick Charbonneau: in- and out-of-equilibrium dynamical properties ofself-assembly. Important phenomena, such as colloidal microphase formation, protein aggregation.Henry Greenside: Theory and simulations of spatiotemporal patterns in fluids; synchronization and correlations in neuronal activity associated with bird song. Daniel Gauthier: Experiments on networks of chaotic elements; generation and control of high speed chaos in electronic and optical systems; electrodynamics of cardiac tissue and the onset of fibrillation.Jian-Guo Liu: Applied mathematics, nonlinear dynamics, complex system, fluid dynamics, computational sciencesRichard Palmer: Theoretical models of learning and memory in neural networks; glassy dynamics in random systems with frustrated interactions.Joshua Socolar: Theory of dynamics of random networks with applications to gene regulation; stress patterns in granular materials; stabilization of periodic orbits in chaotic systems.Stephen Teitsworth: Experiments on nonlinear dynamics of currents in semiconductors.Ying Wu: nonlinear dynamics of charged particle beams, coherent radiation sources, and the development of novel accelerators and light sourcesTom Katsouleas: use of plasmas as novel particle accelerators and light sourcesExperimental Nuclear PhysicsThe Duke physics department is the host of the Triangle Universities Nuclear Laboratory consisting of three experimental facilities: LENA, FN tandem Van de Graff, and The High Intensity Gamma Source (HIGS) at the Free Electron Laser Laboratory.Mohammad Ahmed: Study of few nucleon systems with hadronic and gamma-ray probes.Phillip Barbeau: Experimental Nuclear & Particle Astro-Physics, Double Beta Decay, Neutrinos and Dark MatterHaiyan Gao: Neutron EDM, Precision measurement of proton charge radius, Polarized Compton scattering, neutron and proton transversity, search for phi-N bound state, polarized photodisintegration of 3HeCalvin Howell: quantum chromodynamics (QCD) description of structure and reactions of few-nucleon systems, Big Bang and explosive nucleosynthesis, and applications of nuclear physics in biology, medicine and national security Werner Tornow: weak-interaction physics, especially in double-beta decay studies and in neutrino oscillation physics using large scale detectors at the Kamland project in Japan.Henry Weller: Using radiative capture reactions induced by polarized beams of protons and deuterons to study nuclear systemsYing Wu: nonlinear dynamics of charged particle beams, coherent radiation sources, and the development of novel accelerators and light sourcesTheoretical Nuclear and Particle PhysicsSteffen A. Bass: Physics of the Quark-Gluon-Plasma (QGP) and ultra-relativistic heavy-ion collisions used to create such a QGP under controlled laboratory conditions.Shailesh Chandrasekharan: Quantum Critical Behavior in Fermion Systems, Using the generalized fermion bag algorithm, Applications to Graphene and Unitary Fermi Gas.Thomas Mehen: Quantum Chromodynamics (QCD) and the application of effective field theory to hadronic physics.Berndt Müller: Nuclear matter at extreme energy density; Quantum chromodynamics.Roxanne P. Springer: Weak interactions (the force responsible for nuclear beta decay) and quantum chromodynamics (QCD, the force that binds quarks into hadrons).Geometry and Theoretical PhysicsPaul Aspinwall: String theory is hoped to provide a theory of all fundamental physics encompassing both quantum mechanics and general relativity.Hubert Bray: geometric analysis with applications to general relativity and the large-scale geometry of spacetimes.Ronen Plesser: String Theory, the most ambitious attempt yet at a comprehensive theo ry of the fundamental structure of the universe.Arlie Petters: problems connected to the interplay of gravity and light (gravitational lensing, general relativity, astrophysics, cosmology)Quantum Optics/Ultra-cold atomsDaniel Gauthier: Topics in the fields of nonlinear and quantum optics, and nonlinear dynamical systems.Jungsang Kim: Quantum Information & Integrated Nanoscale SystemsMaiken H. Mikkelsen: Experiments in Nanophysics & Condensed Matter Physics∙Duke University Department of Physics∙Physics Bldg., Science Dr.∙Box 90305∙Durham, NC 27708∙Phone: 919-660-2500∙Fax: 919-660-2525NetID LoginE-Newsletter Sign UpSign up to receive a monthly E-Newsletter or an Annual print Newsletter and keep up with the Physics Department’s scholarly activities∙∙∙∙∙DUKE UNIVERSITY∙GIVING @ DUKE∙WORKING ENVIRONMENT POLICY。
可提高渗吸效率的阴非离子型表面活性剂制备与性能评价

随 着 非 常规 油 气 资源 勘 探 开发 的不 断 发展 ,体 积 压 裂 通 过 沟 通 地 层 微 裂 缝 形 成 复杂 缝 网 提 高 导 流 能 力 成 为 该类 储 层 增 产 的 主要 技 术 方 向n。]。非 常规 油 气 藏 储 集 层 具 有 微 纳 米 级 吼道 ,孔 吼半 径 小 ,压裂 在 形 成复 杂 缝 网 的 同时通 过 人 为 改变 岩 石 润湿性 ,借助毛细管力发生渗吸效应 ,实现油水置 换 ,补 充地层能量 ,对 提高单井产量具有 积极作用 ]。 因此 ,研发一种可以改变岩石润湿性从而发生渗吸 作 用 的 表 面 活 性 剂 显 得 尤 为 重 要 。 目前 对 渗 吸 的 研究 主要 集 中在渗 吸作 用影响因素及 表面活性剂 对 渗 吸作 用 的 影 响机 理 方 面 。研 究 者 认 为 影 响 渗 吸作用 的主要 因素为润湿性 、界面张力 和毛细管力 ]。 表 面 活性 剂 通 过 单 分 子层 吸 附机 理 、离 子 对 机 理 及 胶 束 增 溶 机 理 n叫可 以改 变 岩 石 表 面 润 湿 性 和 油 水界 面张力等 ,进而提高渗吸效率 。表面活性剂在
微 裂 缝 细 小 吼道 发 生 渗 吸 效 应 可 以 提 高单 井 产 量 成 为 近 年 来 非 常 规 油 气 藏 开 发 取 得 的 重要 技 术 认 识 。 目前 ,国 内外 均有 以表 面活 性剂 作 为压 裂段 塞 的现 场 增产 试 验 ,如靖 安 油 田采 用 表 面 活性 剂 WLWn 、美 国耶 茨 油 田(Yates Field)采 用 烷 基 醇 聚 氧 乙烯 醚 n 均 取 得 了较 为 良好 的增 产 效 果 。笔 者 以烷 基 醇 醚 为原 料 合 成 了一 种 阴非 离 子 型 表 面活 性剂 ,通过核磁共振仪表征 了产物的分子结构 ,研 究了表面活性剂 的临界胶束浓度 、界 面张力 、润湿 性 和渗 吸效 率 。
Control Systems Engineering

Control Systems Engineering Research Report2002Control Systems EngineeringSection CROSS(Control,Risk,Optimization,Stochastics and Systems)Faculty of Information Technology and SystemsDelft University of TechnologyPostal address:Visiting addressP.O.Box5031Mekelweg42600GA Delft2628CD DelftThe Netherlands The NetherlandsPhone:+31-15-2785119Fax:+31-15-2786679Email:control@its.tudelft.nlc 2002Control Systems Engineering,rmation Technology and Systems,Delft University ofTechnologyAll rights reserved.No part of the publication may be reproduced in any form by print,photoprint, microfilm or any other means without written permission from the publisher.Contents1Introduction11.1Overview (1)1.2Address and location (3)1.3Staffin2002 (4)2Intelligent modeling,control&decision making52.1Affordable digitalfly-by-wireflight control systems for small commercial aircraft52.2Intelligent adaptive control of bioreactors (6)2.3Fuzzy control of multivariable processes (7)2.4Neuro-fuzzy modeling in model-based fault detection,fault isolation and con-troller reconfiguration (7)2.5Intelligent molecular diagnostic systems (7)2.6Model based optimization of fed-batch bioprocesses (9)2.7Estimation of respiratory parameters via fuzzy clustering (10)2.8Fuzzy model based control with use of a priori knowledge (10)3Distributed and hybrid systems123.1Modeling and analysis of hybrid systems (12)3.2Model predictive control for discrete-event systems (13)3.3Model predictive control for piece-wise affine systems (13)3.4Model predictive control for hybrid systems (14)3.5Optimal traffic control (14)3.6Advanced control techniques for optimal adaptive traffic control (15)3.7Optimal transfer coordination for railway systems (16)3.8Real-time control of smart structures (17)4Fault-tolerant control194.1Model-based fault detection and controller reconfiguration for wind turbines.194.2Model-based fault detection and identification of sensor and actuator faults forsmall commercial aircraft (20)5Nonlinear analysis,control and identification215.1System identification of bio-technological processes (21)5.2Classification of buried objects based on ground penetrating radar signals..215.3Control of a jumbo container crane(JCC project) (22)5.4X-by-wire (23)5.5Analysis and design of nonlinear control systems for switching networks (24)5.6Bounding uncertainty in subspace identification (25)5.7New passivity properties for nonlinear electro-mechanical systems (26)5.8Relating Lagrangian and Hamiltonian descriptions of electrical circuits (27)5.9Discrete-time sliding mode control (27)5.10Nonlinear control systems analysis (28)5.11Model and controller reduction for nonlinear systems (28)5.12Robust and predictive control using neural networks (29)5.13The standard predictive control problem (30)5.14Predictive control of nonlinear systems in the process industry (30)5.15Identification of nonlinear state-space systems (31)5.16Development of computationally efficient and numerically robust system iden-tification software (32)1Introduction1.1OverviewThis report presents an overview of the ongoing research projects during2002at the Control Systems Engineering(CSE)group of the Faculty of Information Technology and Systems of Delft University of Technology.As revealed by the new logo of the group,a number of major changes have taken place. Three of these major events will be briefly discussed.First,the stronger emphasis on a systems oriented research approach has motivated a change of the name from Control Laboratory into Control Systems Engineering group.Second,in September2001Prof.dr.ir.M.Verhaegen was appointed as the new chairman of the CSE group.With his arrival an impulse was given to strengthen the development of new methods and techniques for identification and fault-tolerant control design.The primary focus of the programme development is to formulate new research initiatives and to initiate research alliances with established Dutch and European research-oriented laboratories and industry.New research proposals will be formulated within the four main themes:intelligent modeling,control and decision making;distributed and hybrid systems;fault-tolerant control; and analysis,control and identification of nonlinear systems—as depicted by the vertical columns in Figure1.The overall focus will remain on complex nonlinear systems,new application directions,however,may be included,such as adaptive optics which more and more rely on advanced control techniques.The CSE group is also taking part in new research programme definitions of the Faculty of Information Technology and Systems,such as the Intelligent Systems Consortium(iSc)chaired by Prof.P.Dewilde.Third,the CSE group strives to strengthen the research and teaching cooperation in the area of control systems engineering with other leading Systems and Control Engineering groups in Delft.To accomplish this goal,the CSE actively supports the creation of a joint Delft Center on Systems and Control Engineering.The research interests of the CSE group are focused on the following areas:•Intelligent modeling,control and decision making:black-box and gray-box modeling of dynamic systems with fuzzy logic and neural net-works,and design of controllers using fuzzy set techniques.•Distributed and hybrid systems:analysis and control methods,multi-agent control,hierarchical control,and model pre-dictive control of hybrid systems.•Fault-tolerant control:fault detection and isolation with system identification and extended Kalmanfiltering, probabilistic robust control.•Nonlinear analysis,control and identification:nonlinear predictive control,sliding mode control,iterative learning control,nonlinear dynamic model inversion,Lagrangian and Hamiltonian modeling and control frame-works(energy based),identification of a composite of numerical local linear state space models to approximate nonlinear dynamics.The goal of the CSE group is to develop innovative methodologies in thefields indicated above.An important motive in demonstrating their relevance is to cooperate with nationalFigure1:Overview of the research topics of the Control System Engineering group. and international research organizations and industry to validate the real-life potential of the new methodologies.The main applicationfields are:•Smart structures:X-by-wire,road traffic sensors,high performance control using smart materials,adaptive optics,laboratory-on-a-chip,micro robotics.•Power engineering:switching networks,power distribution and conversion,condition monitoring in off-shore wind turbines.•Telecommunication•Motion control:autonomous and intelligent mobile systems,mobile robots,container transport,aircraft and satellite control,traffic control.•Bioprocess technology:fermentation processes,waste-water treatment.The CSE group currently consists of27scientific and support staff:8permanent scientific staff,10PhD students,2postdoctoral researchers,and7support personnel.The research activities are for a large partfinanced from external sources including the Dutch National Science Foundation(STW),Delft University of Technology,the European Union,and indus-try.Additional information can be found at http://lcewww.et.tudelft.nl/.1.2Address and locationControl Systems EngineeringFaculty of Information Technology&SystemsDelft University of TechnologyPostal address:P.O.Box50312600GA DelftThe NetherlandsVisiting address:Mekelweg42628CD DelftThe NetherlandsPhone:+31-15-2785119Fax:+31-15-27866791.3Staffin2002Scientific staffProf.dr.ir.M.H.G.VerhaegenProf.dr.ir.J.HellendoornProf.dr.ir.R.Babuˇs kaDr.ir.T.J.J.van den BoomDr.ir.B.De SchutterDr.ir.J.B.KlaassensDr.ir.J.M.A.ScherpenDr.ir.V.VerdultPhD students&postdoctoral researchers Dr.J.Clemente GallardoIr.P.R.FraanjeIr.A.HegyiIr.K.J.G.HinnenIr.D.JeltsemaR.Lopez Lena,MScIr.S.Meˇs i´cIr.M.L.J.OosteromIr.G.PastoreNon-scientific staffC.J.M.DukkerIng.P.M.EmonsP.MakkesIng.W.J.M.van GeestD.NoteboomG.J.M.van der WindtIng.R.M.A.van PuffelenAdvisorsProf.ir.G.Honderd,em.Prof.ir.H.R.van Nauta Lemke,em. Prof.ir.H.B.Verbruggen,em.2Intelligent modeling,control&decision makingThis research theme focuses on the use of fuzzy logic,neural networks and evolutionary al-gorithms in the analysis and design of models and controllers for nonlinear dynamic systems. Fuzzy logic systems offer a suitable framework for combining knowledge of human experts with partly known mathematical models and data,while artificial neural networks are effec-tive black-box function approximators with learning and adaptation capabilities.Evolution-ary algorithms are randomized optimization techniques useful in searching high-dimensional spaces and tuning of parameters in fuzzy and neural systems.These techniques provide tools for solving complex design problems under uncertainty by providing the ability to learn from past experience,perform complex pattern recognition tasks and fuse information from various sources.Application domains include fault-tolerant control,nonlinear system identification, autonomous and adaptive control,among others.2.1Affordable digitalfly-by-wireflight control systems for small commer-cial aircraftProject members:M.L.J.Oosterom,R.Babuˇs ka,H.B.VerbruggenSponsored by:European Community GROWTH project ADFCS–IIThe objective of this project is to apply thefly-by-wire(FBW)technology inflight control systems of a smaller category of aircraft(see Figure2).In FBW digitalflight control systems, there is no direct link between the control stick and pedals,which are operated by the pilot, and the control surfaces.All measured signals,including the pilot inputs,are processed by the flight control computer that computes the desired control surface deflections.This scheme enables theflight control engineer to alter the dynamic characteristics of the bare aircraft through an appropriate design of theflight control laws.Moreover,important safety features can be included in the control system,such asflight envelope protection.This increases the safety level compared to aircraft with mechanical control systems.Our task in the project is to assess the benefits and to verify the validity of the soft-computing techniques in the FBW control system design and sensor management.These novel techniques are combined with standard,well-proven methods of the aircraft industry.Figure2:The Galaxy business jet(left)and validation of the control system through pilot-in-the-loop simulations at the Research Flight Simulator of the NLR(right).Figure3:The experimental laboratory setup(left)and the basic model-based adaptive control scheme(right).The research topics are the design of gain-scheduled control laws,fault detection,isolation and reconfiguration,and an expert system monitoring of the overall operational status of both the pilot and the aircraft.For control design,fault detection and identification system,fuzzy logic approaches are adopted in order to extend linear design techniques to nonlinear systems. Moreover,a neuro-fuzzy virtual sensor will be developed in close cooperation with Alenia to replace hardware sensors.For the pilot-aircraft status monitor a fuzzy expert system will be developed that has the functionality of a warning and advisory/decision aiding system.2.2Intelligent adaptive control of bioreactorsProject members:R.Babuˇs ka,M.Damen,S.Meˇs i´cSponsored by:SenterThe goal of this research is the development and implementation of a robust self-tuning con-troller for fermentation processes.To ensure an optimal operating conditions,the pH value, the temperature and the dissolved oxygen concentration in the fermenter must be controlled within tight bounds.Ideally,the same control unit should be able to ensure the required performance for a whole variety of fermentation processes(different microorganisms),differ-ent scales(volume of1liter to10000liters)and throughout the entire process run.Figure3 shows an experimental laboratory setup used in this project.The main control challenge is the fact that the dynamics of the system depend on the particular process type and scale and moreover are strongly time-varying,due to gradual changes in the process operating conditions.Controllers withfixed parameters cannot fulfill these requirements.Self-tuning(adaptive) control is applied to address the time-varying nature of the process.Among the different types of adaptive controllers(model-free,model-based,gain-scheduled,etc.),the model-based approach is pursued.The model is obtained through a carefully designed local identification experiment.Special attentions is paid to the robustness of the entire system in order to ensure safe and stable operation under all circumstances.The main contribution of this research is the development,implementation and experimental validation of a complete self-tuning control system.The robustness of the system is achieved by combining well-proven identification and control design methods with a supervisory fuzzy expert system.This research is being done a cooperation between Applikon Dependable Instruments B.V.,Schiedam,Faculty of Electrical Engineering,Eindhoven University of Technology and Faculty of Information Technology and Systems and Kluyver Laboratory for Biotechnology, both at Delft University of Technology.2.3Fuzzy control of multivariable processesProject members:R.Babuˇs ka,S.Mollov,H.B.VerbruggenFuzzy control provides effective solutions for nonlinear and partially unknown processes, mainly because of its ability to combine information form different sources,such as avail-able mathematical models,experience of operators,process measurements,etc.Extensive research has been devoted to single-input single-output fuzzy control systems,including mod-eling and control design aspects,analysis of stability and robustness,adaptive control.Mul-tivariable fuzzy control,however,have received considerably less attention,despite strong practical needs for multivariable control solutions,indicated among otherfields from process industry,(waste)water treatment,or aerospace engineering.Yet,theoretical foundations and methodological aspects of multivariable control are not well developed.This research project focuses on the use of fuzzy logic in model-based control of multiple-input,multiple-output(MIMO)systems.Recent developments include effective optimization techniques and robust stability constraints for nonlinear model predictive control.The devel-oped predictive control methods have been applied to the design of an Engine Management System for the gasoline direct injection engine benchmark,developed as a case study within the European research project FAMIMO(see Figure4).An extension of the Relative Gain Array approach has been proposed that facilitates the analysis of interactions in MIMO fuzzy models.2.4Neuro-fuzzy modeling in model-based fault detection,fault isolationand controller reconfigurationProject members:M.H.G.Verhaegen,J.Hellendoorn,R.Babuˇs ka,S.Kanev,A.Ichtev Sponsored by:STWMost fault tolerant control systems rely on two modules:(model-based)fault detection and isolation module and controller reconfiguration module.The two key elements in designing these two systems are the development of a mathematical model and a suitable decision mechanism to localize the failure and to select a new controller configuration.This project focuses on the development of a design framework in which the mathematical model and the corresponding observer are represented as a composition of local models,each describing the system in a particular operating regime or failure mode.The use of fuzzy Takagi-Sugeno models for residual generation has been investigated.On the basis of residuals soft fault detection and isolation and controller reconfiguration are performed.2.5Intelligent molecular diagnostic systemsProject members:L.Wessels,P.J.van der Veen,J.HellendoornAir BurngasesFigure4:Fuzzy predictive control of a gasoline directinjection engine. Sponsored by:DIOC-5:Intelligent Molecular Diagnostic SystemsIt is the goal of the DIOC-5(DIOC:Delft Interfaculty Research Center)program to produce an Intelligent Molecular Diagnostic System(IMDS).The IMDS will consist of two basic com-ponents:a measurement device and an information processing unit(IPU).The measurement device is a chemical sensor on a chip,which will be capable of rapidly performing vast num-bers of measurements simultaneously,consuming a minimal amount of chemical reagents and sample(see Figure5).Figure5:A prototype IMDS chip containing a matrix of25pico-liter wells.The IPU transforms the complex,raw measurements obtained from the sensor into output that can be employed as high-level decision support in various application domains.See[41]for a possible realization of the IPU.Members of the Control Systems Engineering group and the Information and Communica-tion Theory group are responsible for the realization of the Information Processing Unit.Un-raveling the metabolic processes and the associated regulatory mechanisms of yeast is a very interesting application area for the DIOC-5technology.We are focusing on problems associ-ated with gene and protein levels,and will integrate this information with existing knowledge about metabolic processes developed at the Kluyver Laboratory(One of the DIOC-5part-ners).More specifically,gene expression data and protein concentration measurements are employed to model the genetic networks,i.e.,to postulate possible‘genetic wiring diagrams’based on the expression data(See[40]for some preliminary results in this area.) It is envisaged that at the end of this project,genetic network information,protein func-tional knowledge and metabolic models can be integrated into a single hierarchical model, capable of providing metabolic engineers with greater insight into the yeast metabolism.For additional information see the IMDS Web page.12.6Model based optimization of fed-batch bioprocessesProject members:J.A.Roubos,P.Krabben,R.Babuˇs ka,J.J.Heijnen,H.B.Verbruggen Sponsored by:DIOC-6:Mastering the Molecules in Manufacturing,DSM Anti Infectives Many biotechnological production systems are based on batch and fed-batch processes.Op-timization of the product formation currently requires a very expensive and time consuming experimental program to determine the optima by trial and error.The aim of this project is to find a more efficient development path for fed-batch bioprocesses by an optimal combination of experiments and process models.The two main research topics of this project are:•Development of a user friendly modeling environment for fed-batch processes.The soft-ware tool must be able to use different types of knowledge coming from experts,experi-ments andfirst-principles,i.e.,conservation laws.New modeling methods such as fuzzy logic,neural networks and hybrid models will be used.•Iterative optimal experiment design.First some basic experiments can be done to esti-mate some preliminary parameters for the system.The idea is to make a rough model to design the next experiment.First,a stoichiometric model is made and thereafter a structured biochemical model that will be gradually improved according to the fermen-tation data.The main objective is to predict the right trends.The actual values are less important at the initial stages.Once the model is sufficient in terms of quantitative prediction of the production process for a variable external environment,it will be used to determine optimal feeding strategies for the reactor in order to improve product quality and/or quantity.These feeding strategies will be applied in an on-line process control environment.Recent developments and publications can be found at the project Web page2.1http://www.ph.tn.tudelft.nl/Projects/DIOC/Progress.html2http://lcewww.et.tudelft.nl/˜roubos/02401020Time [s]p h a s e 1p h a s e 2p h a s e 3phase 4P r e s s u r e [h P a ]Figure 6:Partitioning of the respiratory cycle is obtained automatically by fuzzy clustering.Each segment represents a characteristic phase of the respiratory cycle.2.7Estimation of respiratory parameters via fuzzy clusteringProject members:R.Babuˇs ka,M.S.Lourens,A.F.M.Verbraak and J.Bogaard (University Hospital Rotterdam)The monitoring of respiratory parameters estimated from flow-pressure-volume measurements can be used to assess patients’pulmonary condition,to detect poor patient-ventilator interac-tion and consequently to optimize the ventilator settings.A new method has been investigated to obtain detailed information about respiratory parameters without interfering with the ven-tilation.By means of fuzzy clustering,the available data set is partitioned into fuzzy subsets that can be well approximated by linear regression models locally.Parameters of these models are then estimated by least-squares techniques.By analyzing the dependence of these local parameters on the location of the model in the flow-volume-pressure space,information on the patients’pulmonary condition can be gained.The effectiveness of the proposed approaches has been studied by analyzing the dependence of the expiratory time constant on the volume in patients with chronic obstructive pulmonary disease (COPD)and patients without COPD.2.8Fuzzy model based control with use of a priori knowledgeProject members:R.Babuˇs ka,J.Abonyi (University of Veszpr´e m,Hungary)Effective development of nonlinear dynamic process models is of great importance in the application of model-based control.Typically,one needs to blend information from different sources:experience of operators and designers,process data and first principle knowledge formulated by mathematical equations.To incorporate a priori knowledge into data-driven identification of dynamic fuzzy models of the Takagi-Sugeno type a constrained identification algorithm has been developed,where the constrains on the model parameters are based on the knowledge about the process stability,minimal or maximal gain,and the settling time.The algorithm has been successfully applied to off-line and on-line adaptation of fuzzy models.When no a priori knowledge about the local dynamic behavior of the process is available, information about the steady-state characteristic could be extremely useful.Because of the difficult analysis of the steady-state behavior of dynamic fuzzy models of the Takagi-Sugeno type,block-oriented fuzzy models have been developed.In the Fuzzy Hammerstein(FH) model,a static fuzzy model is connected in series with a linear dynamic model.The obtained FH model is incorporated in a model-based predictive control scheme.Results show that the proposed FH modeling approach is useful for modular parsimonious modeling and model-based control of nonlinear systems.3Distributed and hybrid systemsHybrid systems typically arise when a continuous-time system is coupled with a logic con-troller,or when we have a system in which external inputs or internal events may cause a sudden change in the dynamics of the system.So hybrid systems exhibit both continuous-variable and discrete-event behavior.Due to the intrinsic complexity of hybrid systems control design techniques for hybrid systems we could either focus on special subclasses of hybrid sys-tems,or use a distributed or hierarchical approach to decompose the controller design problem into smaller subproblems that are easier to solve.In our research we use both approaches.3.1Modeling and analysis of hybrid systemsProject members:B.De Schutter,W.M.P.H.Heemels(Eindhoven University of Technology), A.Bemporad(ETH Z¨u rich)Hybrid systems arise from the interaction between continuous-variable systems(i.e.,systems that can be described by a system of difference or differential equations)and discrete-event systems(i.e.,asynchronous systems where the state transitions are initiated by events;in general the time instants at which these events occur are not equidistant).In general we could say that a hybrid system can be in one of several modes whereby in each mode the behavior of the system can be described by a system of difference or differential equations, and that the system switches from one mode to another due to the occurrence of an event (see Figure7).We have shown that several classes of hybrid systems:piecewise-affine systems,mixed logical dynamical systems,complementarity systems and max-min-plus-scaling systems are equivalent[6,7,24,25].Some of the equivalences are established under(rather mild)addi-tional assumptions.These results are of paramount importance for transferring theoreticalFigure7:Schematic representation of a hybrid system.properties and tools from one class to another,with the consequence that for the study of a particular hybrid system that belongs to any of these classes,one can choose the most convenient hybrid modeling framework.Related research is described under Project3.3.In addition,we have also shown an equivalence between two type of mathematical pro-gramming problems:the linear complementarity problem(LCP)and the extended linear complementarity problem(ELCP)[17].More specifically,we have shown that an ELCP with a bounded feasible set can be recast as an LCP.This result allows us to apply existing LCP algorithms to solve ELCPs[16].3.2Model predictive control for discrete-event systemsProject members:B.De Schutter,T.J.J.van den BoomModel predictive control(MPC)is a very popular controller design method in the process industry.An important advantage of MPC is that it allows the inclusion of constraints on the inputs and ually MPC uses linear discrete-time models.In this project we extend MPC to a class of discrete-event systems.Typical examples of discrete-event systems are:flexible manufacturing systems,telecommunication networks,traffic control systems, multiprocessor operating systems,and logistic systems.In general models that describe the behavior of a discrete-event system are nonlinear in conventional algebra.However,there is a class of discrete-event systems–the max-plus-linear discrete-event systems–that can be described by a model that is“linear”in the max-plus algebra.We have further developed our MPC framework for max-plus-linear discrete-event systems and included the influences of noise and disturbances[33,34,35,36,37].In addition,we have also extended our results to discrete-event systems that can be described by models in which the operations maximization,minimization,addition and scalar multiplication appear[22], and to discrete-event systems with both hard and soft synchronization constraints[19](see also Project3.7).3.3Model predictive control for piece-wise affine systemsProject members:B.De Schutter,T.J.J.van den BoomWe have extended our results on model predictive control(MPC)for discrete event systems (see Project3.2)to a class of hybrid systems that can be described by a continuous piecewise-affine state space model.More specifically,we have considered systems of the formx(k)=P x(x(k−1),u(k))y(k)=P y(x(k),u(k)),where x,u and y are respectively,the state,the input and the output vector of the system,and where the components of P x and P y are continuous piecewise-affine(PWA)scalar functions,i.e.,functions that satisfy the following conditions:1.The domain space of f is divided into afinite number of polyhedral regions;2.In each region f can be expressed as an affine function;3.f is continuous on any boundary between two regions.。
不规则波浪在陡坡上非线性传播变形的试验研究

水 运 工 程
Po r t& W a t e r wa y En g i n e e r i ng
Mar . 2 01 3
第 3期
总第 4 7 7期
No . 3 S e r i a l NO . 4 7 7
■ 非 线 不 性 规 于 传 则 博 播 波 变 浪 形 在 的 陡 试 坡 验 上 研 究
p ur p o s e . The r e s u l t s i n di c a t e t ha t t he wa v e h e i g ht s i n t wo c a s e s o b e y t h e Ra y l e i g h d i s t r i b u t i o n bo t h a t t he o f f s h o r e
关键 词 :不规 则 波浪 ; 变浅 ;非 线 性 相 互 作 用 ;波 高分 布 ; 小波 二 阶 谱 ;低 频 波 浪
中图分类号 :T v 1 3 9 . 2
文献标志码 :A
文章编号 :1 0 0 2 — 4 9 7 2 ( 2 0 1 3 ) 0 3 — 0 0 3 6 — 0 9
J O N S WA P 谱 为靶 谱 生成 了两组随机波浪 。试验 结果显 示 ,在 坡前常水深 区域 和坡顶 ,两种 波况下波 高分布均符合 瑞利分
布 ;但 是 在 变 浅 区域 两 种 波 况 的 波 高 分 布 却 不 尽 相 同。 应 用基 于 小波 变换 的二 阶相 位 谱 来分 析 波浪 在 传 播 过 程 中的 非 线性
La b o r a t o r y s t ud y o f n o nl i ne a r t r a n s f o r ma t i o n o f i r r e g ul a r wa v e s o v e r a s t e e p s l o pe
Jeffcot转子_滑动轴承系统不平衡响应的非线性仿真

振 动 与 冲 击第18卷第1期JOU RNAL O F V I BRA T I ON AND SHOCK V o l.18N o.11999 Jeffcot转子2滑动轴承系统不平衡响应的非线性仿真Ξ王德强 张直明(山东省内燃机研究所) (上海大学轴承研究室)摘 要 本文用动力仿真法考察了Jeffco t转子2椭圆轴承系统的不平衡响应。
计入了轴承油膜力的非线性。
仿真计算前,先以非定常雷诺方程和雷诺破膜条件为依据,生成了轴瓦非定常油膜力数据库。
用龙格2库塔法对运动方程作步进积分,同时反复对轴瓦力数据库进行插值以获得轴承力的瞬时值。
考察了支撑于一对椭圆轴承上的Jeffco t转子的不平衡响应。
所得的动力学行为以及转子和轴颈的涡动轨迹,均与线性动力学(以轴承的线性化动特性系数为依据)所得的结果相比较。
两者虽在很小的不平衡量下吻合良好,但凡当不平衡量不是很小时就有显著差别。
可见有必要计入油膜力的非线性,特别是当需要计算大不平衡量下的不平衡响应时。
关键词:非线性仿真,不平衡响应,转子动力学中图分类号:TH11330 前 言在工程实践中,常常用线性动力理论来计算转子2滑动轴承系统的不平衡响应,即:计算时以线性化的轴承动力特性(轴承的八个刚度和阻尼)来表达轴承油膜的动态力[1]。
但油膜力实际上是非线性的动力元素,因此这样的线性化不可避免地要导致不平衡响应计算中的误差。
本文目的在于用非线性和线性动力学两种计算来考察不平衡响应,并作比较,以明确其异同。
符 号c m in 轴承最小半径间隙(m) x j、y j 以c m in为参考的轴颈中心坐标无量纲值d轴承直径(m)x r、y r以c m in为参考的转子中心坐标无量纲值e u转子质量中心的偏心距(m)Λ润滑油的动力粘度(Pa.s)E u质量中心的相对偏心(e u c m in)F轴承的静载荷(N)f轴在自重下的静挠度(m)Ξ转子角速度Γ轴的相对挠度(f c m in)Ξk转子固有频率l轴承长度(m)8相对速度(Ξ Ξk)SO k以转子固有频率为参考的轴承7m in轴承的最小间隙化Somm erfeld数7m in=c m in rSO k=FΩ3m in d lΛΞk1 线性分析本文以Jeffco t转子2轴承系统(图1)为考察对象。
滚动轴承JEFFCOTT转子系统非线性动力响应分析_张耀强

振 动 与 冲 击 JOURNAL OF V IBRATION AND SHOCK
Vol. 27 No. 5 2008
滚动轴承 - JEFFCO TT转子系统非线性动力响应分析
张耀强 1, 2 , 陈建军 1 , 唐六丁 2 , 林立广 1
(1. 西安电子科技大学 机电工程学院 ,西安 710071; 2. 河南科技大学 工程力学研究所 ,河南 洛阳 471003)
数 , Fr 为作用在转子上的恒定垂直力 。 滚动轴承运转时 ,其滚珠依次通过载荷区 , 当载荷
的作用线下有滚珠和无滚珠时 , 两者的径向刚度是不
相等的 。滚动轴承运转时 , 滚珠每通过载荷区一次 , 就
产生一次振动 , 这即为变柔度 (变刚度 )振动 [8 ] 。变柔
度振动的频率
fvc与滚珠公转的角速度
水平方向的位移 。
如果考虑到轴承径向游隙
λ 0
,
则接
触变形量
ui 可
表示为 :
ui
=
xco sθi
+ y sinθi
-
λ 0
(6)
如果计算得到的 ui Φ 0, 则表示第 i个滚珠没有产生接
触变形 。
由于赫兹弹性接触 , 滚珠 - 滚道间的接触变形产
生了一个非线性的恢复力 。将式 ( 6)代入式 ( 3 ) , 得到
假设外圈及轴承座固定不动 ,可得 :外圈 : 线速度
V0
=
0,
角速度
ω 0
= 0;内圈 :线速度
Vi
=ωR
i
,
角速度
ω i
=ω;其中 ω为转子的角速度 ; Ri 和 R0 分别是内外圈
滚道半径 。
未折叠蛋白反应在强噪声致豚鼠耳蜗细胞损伤过程中的作用

未折叠蛋白反应在强噪声致豚鼠耳蜗细胞损伤过程中的作用薛秋红;陈小林;龚树生;谢静;陈佳;何坚【摘要】Objective To study the unfolded protein glucose-regulated protein 78 (GRP78) expression level after intense noise exposure,and to find out the relationship between UPR and the intense noise induced cochlea cell damage. Methods Forty-eight guinea pigs were randomly divided into 6 groups(8 guinea pigs/group). The guinea pigs in the experiment groups were exposed to 4 kHz narrow band noise at 120 dB SPL for 4 housr while aninals in control group received no noise exprsure. Auditory brainstem response(ABR) of the guinea pigs in experiment and control groups were tested at 3 hours, 1, 4, 14,30 days post noise exposure. Four guinea pig's cochleas from each group were used for paraffin sectioning, and the rest was used for the total protein extraction. Expression of Bip/GRP78 was studied by immunohistochemistry sectioning and western blot. Results There were significantly higher expressions of Tunel-Positve cells in the OHC,SGC and SV in experiment groups compared with those in the controi group (P<0.01). Protein levels ofBip/GRP78 were significantly increased after noise exposure compared with those in the control group (P<0.01). Conclusion After intense noise exposure, UPR protection mechanisms were initiated and by upregulating the expression of molecular chaperones Bip/GRP78, folded proteins were correctly guided, thus reducing cell damage. This may be one of the endogenous protective mechanisms in the guinea pig cochlea.%目的探讨未折叠蛋白反应(unfolded protein response,UPR)标志物葡萄糖调节蛋白78(Bip/GRP78)在强噪声致豚鼠耳蜗细胞损伤中的作用.方法 48只豚鼠随机分为6组,分别为健康对照组(不给噪声暴露)和强噪声暴露后3 h、1 d、4 d、14 d、30 d 组,每组8只,噪声暴露的5组豚鼠在120 dB SPL、4 kHz窄带噪声环境暴露4 h 后,各组豚鼠于相应时间点处死前及对照组均测试听性脑干反应(ABR),然后每组各取4只豚鼠耳蜗作石蜡切片,余4只豚鼠提取耳蜗总蛋白.用免疫组化及Western Blot方法检测Bip/GRP78的表达及其在耳蜗的分布.结果强噪声暴露后各组Bip/GRP78蛋白表达明显高于正常组,且各时间点都维持在比较高的水平,Bip/GRP78蛋白在噪声暴露后各组豚鼠耳蜗的内外毛细胞、螺旋神经节细胞、侧壁细胞均有表达.结论强噪声暴露后,启动UPR保护机制,通过上调分子伴侣Bip/GRP78的表达,引导蛋白质正确折叠,降低细胞损伤,可能是耳蜗内源性保护机制之一.【期刊名称】《听力学及言语疾病杂志》【年(卷),期】2011(019)002【总页数】4页(P149-152)【关键词】未折叠蛋白反应;葡萄糖调节蛋白78;强噪声;耳蜗;损伤【作者】薛秋红;陈小林;龚树生;谢静;陈佳;何坚【作者单位】武汉科技大学附属天佑医院耳鼻咽喉科,武汉,430064;武汉科技大学附属天佑医院耳鼻咽喉科,武汉,430064;首都医科大学附属北京同仁医院耳鼻咽喉头颈外科;武汉科技大学附属天佑医院耳鼻咽喉科,武汉,430064;武汉科技大学附属天佑医院耳鼻咽喉科,武汉,430064;武汉科技大学附属天佑医院耳鼻咽喉科,武汉,430064【正文语种】中文【中图分类】R764.43+3内质网是细胞加工蛋白质和储存钙离子的场所,许多理化因素可以导致未折叠或错误折叠蛋白质在内质网的蓄积以及细胞内钙稳态的失衡,这种状态称为内质网应激,近年来有关内质网应激的信号通路与效应的研究已成为热点。
热声载荷下薄壁结构非线性振动响应分析及疲劳寿命预测

根 部的应力响应 , 并基 于 Mi n e r 线性累积损伤理论采 用 G o o d m a n 、 Mo r r o w、 Wa l k e r 和修正 Wa l k e r 应力寿命模型预 测了薄板 梁在不同工况下 的热声疲 劳寿命 。研究 结果 表明 : 薄板粱 的热模 态基频 在其热声疲 劳 问题 中起 主导作用 ; 薄板 梁热屈 曲 后 的非线性 跳变响应将增大应力 幅值 , 从而严重削弱结构 的预期 寿命 ; 噪声载荷 是影 响屈 曲前薄板梁 热声疲劳 寿命 的主 要 因素 , 而热载荷是影 响屈 曲后热声疲劳寿命 的主要 因素。因此 在薄 壁结 构抗 热声 疲劳设计 中必须重点考虑热声载荷联
合作用 的影响 。
关键 词 :薄壁结构 ; 热声载荷 ; 时域分析 ; 非线性跳变响应 ; 雨流法 ; Mi n e r 损伤理论
中图分类号 :V 2 1 5 ; V 4 1 4 文献标识码 :A
No n l i n e a r v i br a t i o n r e s po ns e a n a l y s i s a nd f a t i g ue l i f e pr e d i c t i o n o f a t h i n・ - wa l l e d s t r uc t ur e un de r t he r ma l - - a c o u s t i c l o a d i ng
HE Er — mi n g,L I U F e n g,HU Y a — q i ,ZHAO Zhi — b i n
( S c h o o l o f A e r o n a u t i c s , N o r t h w e s t e r n P o l y t e c h n i c a l U n i v e r s i t y ,X i ’ a n 7 1 0 0 7 2 , C h i n a )