肾透明细胞癌ppt课件

unilateral solitary low-attenuation mass,
large conglomerate masses, or unilateral
nephromegaly
lymphadenopathy elsewhere
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Therapy and prognosis
For suspicious renal lesions, it is crucial to ensure prompt diagnosis in order to select the appropriate surgical procedure and treatment
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Introduction
CCSK was first described as “bone metastasizing renal tumor of childhood” since it has predilection for skeletal metastasis
Bone metastases occur in 40 to 60% of patients with CCSK, unlike less than 2% of patients with Wilms’ tumor
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1 Introduction
2 Clinical presentation
3 CT findings
4 Differential diagnosis
5 Therapy and prognosis
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Introduction
Clear cell sarcoma of the kidney (CCSK) is an uncommon renal neoplasm of childhood. It accounts for 2–5% of all pediatric renal malignancies
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Introduction
CCSK is the second most common renal tumor in children with a mean age of diagnosis overlapping with Wilms tumor
It is known for its morphologic diversity, aggressive behaviour, tendency to recur and metastasis to bone
cystic foci
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CT findings
Axial and coronal image show a large
right hypochondrial soft tissue mass,
almost totally infiltrating the right
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kidney with only a little residual
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CT findings
heterogeneous enhancement with attenuation less than that of normal renal parenchyma
contain areas of low attenuation corresponding to necrosis and cysts
Malignant rhabdoid tumor(MRT) 01.diagnosed between 0-3 years of age 02.extensive metastasis at the time of diagnosis 03.synchronous brain tumor
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Differential diagnosis
normal renal parenchyma
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CT findings
Solid component presented heterogeneous enhancement with a large cystic area and showed tumor vessels with high density
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Introduction
The peak incidence is between 3 and 5 years of age. It is very rare in infants younger than 6 months
It is the most frequently misdiagnosed renal tumor in children, as it is unusual, has varied morphology, and there are no specific diagnostic markers
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Wilms tumor 01.heterogeneous solid renal mass with a “claw sign” 02.tumor extension into the renal vein and IVC in 5-10% 03.most frequently metastasizes to the lungs, bilateral in 4-13%
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Renal cell carcinoma
makes up 1% of all pediatric renal malignancies smaller at presentation calcified in 25%
Lymphoma
multiple bilateral low-attenuation masses
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Clinical presentation
Most of the children were taken to the hospital for abdominal mass
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Clinical presentation
01 abdominal pain 02 hematuria
03 abdominal distention
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CT findings
Diagnosis
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Differential diagnosis
1.Wilms tumor 2.Malignant rhabdoid tumor 3.Renal cell carcinoma 4.Lymphoma
.13DiFra bibliotekferential diagnosis