lecture_1
Lecture_1_2017物理ppt

互相影响
Note on notation: FAB is the force exerted by A on B
Newton’s Third Law, Alternative Statements
n n n
Forces always occur in pairs A single isolated force cannot exist The action force is equal in magnitude to the reaction force and opposite in direction
n
ΣF is the net force
n
This is the vector sum of all the forces acting on the object
n
Newton’s Second Law can be expressed in terms of components:
More About Mass
n
n
n
n n
Mass is an inherent property of an object Mass is independent of the object’s surroundings Mass is independent of the method used to measure it Mass is a scalar quantity The SI unit of mass is kg
Weight will vary with location
一个物体的质量是不会变的,一个scalar【标量】,而其重量是根据引力大小而出来的.
JULIUS SUMNER MILLER VIDEO-N1L [16MIN]
61第六讲_lecture_1_真核细胞启动子及调控元件-讲义R

真核细胞中很多事情都要复杂很多,虽然上周你已经看到了真核细胞和原核细胞的RNA聚合酶看起来很相似,RNA合成的机制也是相同的,但真核细胞的转录在RNA聚合酶的种类、需要的转录因子、转录终止的方式等等很多方面都与原核细胞有着比较大的差异。
除此之外,真核细胞中DNA是包被在核小体中的,要想在体内环境下进行基因的有效起始,还需要更多的包括中介蛋白复合体,染色质重塑复合体等多种因子的共同作用。
原核细胞的一个转录单元中可以包含多个编码基因,而真核细胞中一个转录单元往往只包含单一基因。
差别还真不小是不是,且容我一点一点将真核细胞转录的特点给你从头说起吧。
1、真核细胞的RNA聚合酶我们先从真核细胞的RNA聚合酶说起。
真核细胞中至少含有三种RNA聚合酶,其定位和转录的基因类型各不相同。
RNA 聚合酶I 位于核仁区域,是真核细胞中转录活性最强的RNA 聚合酶,因为他要不停的负责转录大核糖体RNA 前体(45SrRNA 前体,也有文献报道为47SrRNA )。
剪切后产生除5S rRNA 外其他组成核糖体的各种rRNA 。
RNA 聚合酶II 是另一种主要的RNA 聚合酶,它位于核质中,负责转录大多数的编码基因。
包括mRNA 前体分子,小核仁RNA ,小核内RNA ,微小RNA(microRNA)。
在离子强度较高,尤其是Mn2+浓度较高时,活性较高。
RNA 聚合酶III 也位于核浆中,他所负责合成的是tRNA ,5s 核糖体RNA ,和其他一些snRNA (小核内RNA )。
所有这些RNA聚合酶都是多亚基的大蛋白复合体,分子量可以超过500Kd。
对于真核细胞主要的三种RNA聚合酶而言,他们有三个亚基是三种RNA聚合酶共有的。
这里要特别介绍一下的是RNA 聚合酶II最大的亚基中含有一个重要的羧基末端结构域,这个结构域由7个氨基酸残基组成的序列多次重复形成,是RNA 聚合酶II所特有的。
在酵母RNA聚合酶II 的CTD尾巴中七肽序列重复了26次,但哺乳动物中重复次数可以达到50次。
lecture_1__翻译概论

3) In terms of the media by which translation is done: oral, written and machine 从翻译的手段来分类,翻译可分为口译(oral interlingual translation)、笔译(written interlingual translation) 和机器翻译 (machine translation); 4) In terms of the subject matter: 从翻译的题材来分类,翻译可分为专业文献翻译(translation of English for science and technology)、文学翻译(literary translation)和一般性翻译(practical writing translation); 5)In terms of the manner: 从翻译的处理方式来分类,翻译可分为全译(full translation)、 摘译(partial translation)和编译(translation plus editing)。
E-C and C-E Translation Basics
英汉-汉英翻译基础
Lecture 1
Introduction to Translation
I. What is Translation?
1. A story of translation in Bible Long long ago, all the people speak the same language . When they transferred to the east, they found a plain and then lived there. They decided to build a tall tower, so that it can stretch to the heaven and they can live in the heaven. When Jesus saw this, he was afraid that if all the people speak the same language, they can do everything they want. So Jusus went down from the heaven and confused their languages so they couldn’t communicate with each other and they didn’t finish the Bable Tower. Since then, people lived in different places and spoke different languages. Hence comes the translation.
Lecture_1_Introduction

Life in the United States
Life in the United States
The Size of the US
– Imagine that you drove from New York to Los Angeles, stopping only for gas, to eat, and sleep. It would take you four or five days – It takes two days to drive from New York to Florida
Population by Ethnicity
White 71% Black 13% Hispanic 10% Asian 4% Native American 2%
A Nation of Immigration
Immigration is the act of coming to a foreign country to live. The act of leaving one's country to settle in another is called emigration. Immigrants who flee their country because of persecution(迫害), war, or such disasters as famines or epidemics are known as refugees or displaced persons.
Lecture1

01 Warming upWarming upChoose one activity you like to do most and give your reasons.parkour rock climbing campingorienteering whitewater rafting paragliding02 Listening and Speaking01Warming upListen to the dialogue between Mike and Lynn about their weekendactivities. The following words, expressions and sentences may help you.cycling clubmake itgo camping barbecuepostHow was your weekend?I’ve posted some pictures online.They are all camping lovers.Script01Warming upcycling club自行车俱乐部e.g. He had trained hard in his cycling club .他在自行车俱乐部刻苦训练。
BACK01Warming upmake itsucceed in doing sth.成功做到某事e.g. Although she really wanted to come to visit us, she couldn’t make it because of the bad weather.尽管她非常想要来拜访我们,但由于天气糟糕而无法成行。
BACK01Warming up go camping去野营e.g. When we go camping , I hike in the woods.当我们去野营的时候,我在树林里步行。
Lecture_1

Chapter 2 Properties of materials §2.1 Mechanical property §2.2 Electrical property §2.3 Thermal property §2.4 Magnetic property §2.5 Optical property
§ 1.1 Concept and classification 1. Definition 定义 Functional materials:with excellent
electric, magnetic, thermal, sonic, mechanical, chemical and biochemical properties, can be transferred from each other and used as non-structural materials.
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1. 1 Nano metallic materials
Size: < 100nm Types: 纳米晶稀土永磁材料: 纳米晶稀土永磁材料 2000年,日本三荣化成株式会社 铁粉附着钕,磁场中烧结+真空烧结 制得各向异性磁体 各向异性磁体
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磁性液体:铁磁流体,具有磁性及 具有磁性及 磁性液体 流动性(我国,钢铁研究总院) 流动性 由纳米级得脆性颗粒分散在载液中 形成稳定的胶体,在重力、离心力 在重力、 在重力 及强磁场作用下不分离。 及强磁场作用下不分离 1963年美国宇航局:解决太空服头 盔转动密封问题
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1. Functionally metallic materials
Some are developed and widely applied: 形状记忆合金:军事、汽车 Some are less developed but with potential opportunities: 超导合金材料、减振合金材料
Lecture_1_introduction

Problems of Vision ?
Vision is deceptive
Problems of Vision ?
Vision is deceptive
Problems of Vision ?
Vision is deceptive
Problems of Vision ?
Vision is Inferable (prior knowledge)
应用
距离数据(range data)/图像数据检索/基于图像的绘制
Related Courses
Image Processing
Scientific / medical imaging Pattern Recognition
Computer Graphics
Learning
Artificial Intelligence
to know what is where, by looking.’’ (Marr) Where? What?
What do we use vision for?
Recognize objects people we know things we own Locate objects in space to pick them up Track objects in motion catching a baseball avoiding collisions with cars on the road Recognize actions walking, running, pushing Emotions, gestures
Examples
Examples
Examples
Examples
Lecture-1-Probabilities-Basics(概率基础知识)

• If A, and B are statistically independent, then P(A|B)=P(A) and P(B|A)=P(B) • Bayes rule allows to derive posterior probabilities from prior probabilities
• Probability density:
• The intuitive “what’s the distribution like?” function • • Thus, ,i.e., the derivative of the cdf
9
Other Probability Terms
• Unconditional or prior probabilities represent the state of knowledge before new observations or evidence
• ∑
13
More on Bayes
• Bayes theorem helps us to move any terms from the left to the right and vice versa:
• • • • • P(AB|C)=P(AC|B)*P(B)/P(C) P(AB|C,D)=P(AC|B,D)*P(B|D)/P(C|D) P(A|B)=P(AB)/P(B) P(A|B,C)=P(AB|C)/P(B|C) P(AB)=P(A|B)*P(B)
• P(H)
• A probability distribution (pmf, or pdf) gives values for all possible assignments to a random variable
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16.333:Lecture#1
Equilibrium States
Aircraft performance Introduction to basic terms
Fall200416.3331–1
Aircraft Performance •Accelerated horizontalflightbalance of forces
–Engine thrust T
–Lift L(⊥to V)
–Drag D(�to V)
–Weight W
dV
T−D=m=0for steadyflight
dt
and
L−W=0
Define L=
•1
2
ρV2SC L where
–ρ–air density(standard tables)
–S–gross wing area=¯c×b,
–c¯=mean chord
–b=wing span
–A R–wing aspect ratio=b/c
¯
–Q=1
2
ρV2dynamic pressure –V=speed relative to the air
� �
Fall 2004 16.333 1–2
– C L lift coefficient – for low Mach number, C L = C L α (α − α0) 3 α angle of incidence of wind to the wing 3 α0 is the angle associated with zero lift
• Back to the performance:
1 L = ρV 2
SC L and L = mg
2 2mg
which implies that V = ρSC L
so that
V ∝ C −1/2
L
and we can relate the effect of speed to wing lift
• A key number is stall speed, which is the lowest speed that an aircraft can fly steadily 2mg
V s =
ρSC L max
where typically get C L max at αmax = 10◦
Fall 2004
16.333 1–3
Steady Gliding Flight
• Aircraft at a steady glide angle of γ
• Assume forces are in equilibrium
L − mg cos γ = 0 (1) D + mg sin γ = 0
(2)
Gives that
D C D
tan γ = L ≡
C L
⇒ Minimum gliding angle obtained when C D /C L is a minimum – High L/D gives a low gliding angle
• Note: typically C D = C D min +
2 L
C πA Re
where
is the zero lift (friction/parasitic) drag
– C D min – C 2
lift induced drag
gives the L – e is Oswald’s efficiency factor ≈ 0.7 − 0.85
Fall 2004 16.333 1–4
• Total drag then given by
11 �� D = ρV 2SC D = ρV 2S L
(3)C D min + kC 2
22 1(mg )2 =2 ρV 2SC D min + k 1 ρV 2
S
(4)
2
• So that the speed for minimum drag is
�� �1/4
2mg
k V min drag =
ρS C D min
•Equations:
T−D−W sinγ=0(5)
L−W cosγ=0(6)�which gives
L
cosγ=0
T−D−
sinγ
so that
T−D
tanγ=
L
•Consistent with1–3if T=0since thenγas defined above is negative •Note that for smallγ,tanγ≈γ≈sinγ
R/C=V sinγ≈Vγ≈(T−D)V
L
so that the rate of climb is approximately equal to the excess power available(above that needed to maintain levelflight)
•Equations:
L sinφ=centrifugal force(7)
mV2
=
R
(8)
L cosφ=W=mg(9)
⇒tanφ=V2
Rg
V=Rω
=
Vω
g
(10)
•Note:obtain R min at C L
max
R min(1
2
ρV2SC L
max
)sinφ=
W V2
g
⇒R min=
W/S
1/2ρgC L
max
sinφmax
where W/S is the wing loading andφmax<30◦
Fall 2004 16.333 1–7
• Define load factor N = L/mg . i.e. ratio of lift in turn to weight
N = sec φ = (1 + tan 2 φ)
1/2
�
(11) tan φ = N 2 − 1
(12)
so that
V 2 V 2
R = g tan φ = g √
N 2 − 1
• For a given load factor (wing strength)
R ∝ V 2
• Compare straight level with turning flight
– If same light coefficient
L mg 1 C L = 1 = ρV 2S ≡ N mg ρV t 2
S
ρV 2S 1 222 so that V t = √
N V gives the speed increase (more lift)
• Note that C L constant C D constant ⇒ D ∝ V 2C D
⇒ ⇒ T t ∝ D t ∝ V t 2C D ∼ N
D so that must increase throttle or will descend in the turn。