2,4-二硝基氯苯SDS_Sigma-Aldrich
2,4-二硝基氯苯生产工艺
2,4-二硝基氯苯生产工艺1. 引言2,4-二硝基氯苯是一种重要的有机化工原料，广泛应用于染料、药物和农药等领域。
本文将介绍2,4-二硝基氯苯的生产工艺及其相关情况。
2. 原料准备2,4-二硝基氯苯的生产原料主要包括苯、硝酸、氯化亚铁和硫酸等。
首先，苯经过精制处理，去除杂质，提高反应的纯度。
硝酸和氯化亚铁也需要经过精制处理，以确保原料的质量。
硫酸作为催化剂，起到促进反应的作用。
3. 反应步骤2,4-二硝基氯苯的生产主要通过硝化反应完成。
具体的反应步骤如下：3.1 苯硝化在反应釜中加入苯和硝酸，经过搅拌混合均匀。
然后，加入硫酸作为催化剂，控制反应温度和反应时间。
反应温度一般在50-60摄氏度之间，反应时间一般为2-4小时。
在反应过程中，要保持反应釜内的温度稳定，并进行有效的搅拌以提高反应效率。
3.2 氯化反应苯硝化反应完成后，将反应液加入到氯化釜中。
在氯化釜中，加入氯化亚铁并进行搅拌混合。
反应温度一般控制在60-70摄氏度之间，反应时间为2-3小时。
在反应过程中，要保持反应釜内的温度和搅拌速度稳定，以确保反应的有效进行。
4. 分离与纯化氯化反应完成后，得到的反应产物为混合物。
为了获得纯度较高的2,4-二硝基氯苯，需要进行分离与纯化。
常用的分离方法包括蒸馏、结晶和萃取等。
根据具体情况，选择合适的分离方法进行操作。
5. 产品质量控制在2,4-二硝基氯苯的生产过程中，需要进行产品质量控制。
常用的检测方法包括气相色谱法、红外光谱法和质谱法等。
通过这些方法，可以对产品进行成分分析和纯度检测，确保产品质量符合要求。
6. 安全注意事项在2,4-二硝基氯苯的生产过程中，需要注意安全事项。
硝化反应和氯化反应都是放热反应，因此要控制好反应温度，避免发生危险事故。
同时，要加强通风设备的使用，防止有毒气体的积聚。
在操作中要佩戴好个人防护装备，严格按照操作规程进行操作，确保人身安全。
7. 结论2,4-二硝基氯苯是一种重要的有机化工原料，在染料、药物和农药等领域有广泛应用。
2,4二硝基氯苯理化性质危险有害特性及应急防护措施
身体防护：穿防静电工作服。
手防护：戴一般作业防护手套。
其他防护：工作现场严禁吸烟。实行就业前和定期的体检。避免高浓度吸入。进入罐、限制性空间或其它高浓度区作业，须有人监护。
泄漏处理
迅速撤离泄漏污染区人员至上风处，并立即隔离150m，严格限制出入。切断火源。建议应急处理人员戴自给正压式呼吸器，穿防静电工作服。尽可能切断泄漏源。合理通风，加速扩散。喷雾状水稀释、溶解。构筑围堤或挖坑收容产生的大量废水。如有可能，将漏出气用排风机送至空旷地方或装设适当喷头烧掉。也可以用管路导至炉中、凹地焚之。漏气容器要妥善处理，修复、检验后再用。
重度患者深度昏迷瞳孔缩小肌张力增强频繁抽搐大小便失禁休克肺水肿严重心肌损害等血液碳氧血红蛋白可高于50
2,4二硝基氯苯理化性质、危险有害特性及应急防护措施
标识
中文名：
英文名：
分子式：
分子量：28.01
CAS号：
危险化学品顺序号：
理化性质
性状：。
溶解性：
熔点（℃）：
沸点（℃）：
相对密度（水＝1）：
临界温度（℃）：
贮运
包装标志：UN编号：1016包装分类：
包装方法：钢质气瓶。
储运条件：储存于阴凉、通风的库房。远离火种、热源。库温不宜超过30℃。应与氧化剂、碱类、食用化学品分开存放，切忌混储。采用防爆型照明、通风设施。禁止使用易产生火花的机械设备和工具。储区应备有泄漏应急处理设备。采用刚瓶运输时必须戴好钢瓶上的安全帽。钢瓶一般平放，并应将瓶口朝同一方向，不可交叉；高度不得超过车辆的防护栏板，并用三角木垫卡牢，防止滚动。运输时运输车辆应配备相应品种和数量的消防器材。装运该物品的车辆排气管必须配备阻火装置，禁止使用易产生火花的机械设备和工具装卸。严禁与氧化剂、碱类、食用化学品等混装混运。夏季应早晚运输，防止日光曝晒。中途停留时应远离火种、热源。公路运输时要按规定路线行驶，禁止在居民区和人口稠密区停留。铁路运输时要禁止溜放。
2,4-二硝基氯苯
2,4-二硝基氯苯化学品安全技术说明书第一部分：化学品名称化学品中文名称：2,4-二硝基氯苯化学品英文名称：2,4-dinitrochlorobenzene中文名称2：4-氯-1,3-二硝基苯英文名称2：4-chloro-1,3-dinitrobenzene技术说明书编码：659CAS No.：97-00-7分子式：C6H3ClN2O4分子量：202.56健康危害：本品为皮肤致敏物，60％～80％的接触者发生皮炎，微量接触也能致病。
表现为发痒、灼痛的丘疹、水疱，重者发生剥脱性皮炎。
可引起其他过敏反应，如支气管哮喘等。
本品全身性毒性微弱，偶见引起紫绀和全身中毒症状。
有可能引起肝损害。
燃爆危险：本品可燃，有毒，具致敏性。
第四部分：急救措施皮肤接触：脱去污染的衣着，用酒精擦试局部。
用流动清水冲洗。
就医。
眼睛接触：提起眼睑，用流动清水或生理盐水冲洗。
就医。
吸入：迅速脱离现场至空气新鲜处。
保持呼吸道通畅。
如呼吸困难，给输氧。
如呼吸停止，立即进行人工呼吸。
就医。
食入：饮足量温水，催吐。
就医。
第五部分：消防措施危险特性：可燃。
已知在 150℃下受强烈震动能引起爆炸。
有害燃烧产物：一氧化碳、二氧化碳、氧化氮、氯化氢灭火方法：消防人员须在有防爆掩蔽处操作。
遇大火须远离以防炸伤。
在物料附近失火，须用水保持容器冷却。
灭火剂：雾状水、泡沫、二氧化碳、干粉。
第六部分：泄漏应急处理应急处理：隔离泄漏污染区，限制出入。
切断火源。
建议应急处理人员戴防尘面具（全面罩），穿防毒服。
不要直接接触泄漏物。
小量泄漏：用洁净的铲子收集于干燥、洁净、有盖的容器中。
大量泄漏：收集回收或运至废物处理场所处置。
第七部分：操作处置与储存操作注意事项：密闭操作，提供充分的局部排风。
操作人员必须经过专门培训，严格遵守操作规程。
建议操作人员佩戴自吸过滤式防尘口罩，戴安全防护眼镜，穿防毒物渗透工作服，戴橡胶手套。
远离火种、热源，工作场所严禁吸烟。
使用防爆型的通风系统和设备。
2,4-二硝基氟苯-安全技术说明书MSDS
第1部分化学品及企业标识化学品中文名：2,4-二硝基氟苯化学品英文名：1-fluoro-2,4-dinitrobenzeneCAS号：70-34-8分子式：C6H3FN2O4分子量：186.1产品推荐及限制用途：工业及科研用途。
第2部分危险性概述紧急情况概述：吞咽有害。
造成皮肤刺激。
可能导致皮肤过敏反应。
造成严重眼刺激。
可引起呼吸道刺激。
长期或反复接触可能对器官造成伤害。
GHS危险性类别：急性经口毒性类别4皮肤腐蚀/刺激类别2皮肤致敏物类别1严重眼损伤/眼刺激类别2特异性靶器官毒性一次接触类别3特异性靶器官毒性反复接触类别2标签要素：象形图：警示词：警告危险性说明：H302吞咽有害H315造成皮肤刺激H317可能导致皮肤过敏反应H319造成严重眼刺激H335可引起呼吸道刺激H373长期或反复接触可能对器官造成伤害防范说明：•预防措施：——P264作业后彻底清洗。
——P270使用本产品时不要进食、饮水或吸烟。
——P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
——P261避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
——P272受沾染的工作服不得带出工作场地。
——P271只能在室外或通风良好处使用。
——P260不要吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
•事故响应：——P301+P312如误吞咽：如感觉不适，呼叫解毒中心/医生——P330漱口。
——P302+P352如皮肤沾染：用水充分清洗。
——P332+P313如发生皮肤刺激：求医/就诊。
——P362+P364脱掉沾染的衣服，清洗后方可重新使用——P333+P313如发生皮肤刺激或皮疹：求医/就诊。
——P305+P351+P338如进入眼睛：用水小心冲洗几分钟。
如戴隐形眼镜并可方便地取出，取出隐形眼镜。
继续冲洗。
——P337+P313如仍觉眼刺激：求医/就诊。
——P304+P340如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。
——P312如感觉不适，呼叫解毒中心/医生——P314如感觉不适，须求医/就诊。
1-氯-2,4-二硝基苯-安全技术说明书MSDS
第一部分化学品及企业标识化学品中文名：1-氯-2，4-二硝基苯化学品英文名：1-chloro-2，4-dinitrobenzene；2，4-dinitrochlorobenzene化学品别名：2，4-二硝基氯苯CAS No.：97-00-7EC No.：202-551-4分子式：C6H3ClN2O4第二部分危险性概述紧急情况概述固体。
跟皮肤接触有剧毒。
对皮肤有刺激性。
跟皮肤接触可能会引起敏化作用。
有严重损害眼睛的危险。
对呼吸道有刺激作用。
可能有发生不可逆性作用的危险。
短期暴露有严重损伤健康的危险。
长期暴露有严重损伤健康的危险。
对水生物有剧毒，使用适当的容器，以预防污染环境。
对水生环境可能会引起长期有害作用。
使用适当的容器，以预防污染环境。
GHS危险性类别根据GB30000-2013化学品分类和标签规范系列标准（参阅第十六部分），该产品分类如下：急毒性-皮肤，类别2；皮肤腐蚀/刺激，类别2；皮肤敏化作用，类别1；眼损伤/眼刺激，类别1；特定目标器官毒性-单次接触：呼吸道刺激，类别3；生殖细胞致突变性，类别2；特定目标器官毒性-单次接触，类别1；特定目标器官毒性-重复接触，类别1；危害水生环境-急性毒性，类别1；危害水生环境-慢性毒性，类别1。
标签要素象形图警示词：危险危险信息：皮肤接触致命，造成皮肤刺激，可能导致皮肤过敏反应，造成严重眼损伤，可能造成呼吸道刺激，怀疑会导致遗传性缺陷，对器官造成损害，长期或重复接触会对器官造成伤害，对水生生物毒性极大，对水生生物毒性极大并具有长期持续影响。
预防措施：使用前取得专业说明。
在阅读并明了所有安全措施前切勿搬动。
不要吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
严防进入眼中、接触皮肤或衣服。
作业后彻底清洗。
使用本产品时不要进食、饮水或吸烟。
只能在室外或通风良好之处使用。
受沾染的工作服不得带出工作场地。
避免释放到环境中。
戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
事故响应：如感觉不适，呼叫中毒急救中心/医生。
2,4-二硝基氯苯评价标准
2,4-二硝基氯苯评价标准2,4-二硝基氯苯是一种常见的有机化合物，具有广泛的应用领域，包括农业、工业和医药等领域。
然而，由于其毒性和环境致污性较高，对其评价和监测至关重要。
以下是对2,4-二硝基氯苯评价的标准。
1.毒性评价2,4-二硝基氯苯具有较高的毒性，对人体健康和环境造成潜在风险。
毒性评价应涵盖急性毒性、亚急性毒性、慢性毒性和致癌性等多方面。
可以通过动物实验、细胞毒性实验和计算机模拟等方法来评估2,4-二硝基氯苯的毒性。
2.环境影响评价2,4-二硝基氯苯存在于土壤、水体和空气中，对环境产生潜在的危害。
环境影响评价应包括生物降解性、生物富集性和生态毒性等方面。
可以通过实验室和田间试验来评估2,4-二硝基氯苯在环境中的行为和影响。
3.污染监测对于2,4-二硝基氯苯，监测其在大气、水体和土壤中的浓度和分布是非常重要的。
污染监测可以通过取样和分析方法来进行，例如气相色谱-质谱法、高效液相色谱法和吸附试剂法等。
监测结果可以用于评估2,4-二硝基氯苯的污染程度，并制定相应的保护措施。
4.风险评估基于毒性评价和环境影响评价的结果，可以进行2,4-二硝基氯苯的风险评估。
风险评估应综合考虑人体暴露途径、暴露剂量和潜在风险等因素，以评估2,4-二硝基氯苯对人体健康和环境的潜在危害。
根据风险评估结果，可以制定相关的限值标准和控制措施。
5.监管和管理对于2,4-二硝基氯苯这类有毒物质，必须进行严格的监管和管理。
包括制定相关的法规和标准、监督检查和追踪调查等。
监管和管理的目标是减少2,4-二硝基氯苯对人体健康和环境的影响，确保其合理使用和安全处置。
综上所述，对2,4-二硝基氯苯的评价应包括毒性评价、环境影响评价、污染监测、风险评估以及监管和管理等方面。
这些评价标准能够为2,4-二硝基氯苯的合理使用和环境保护提供科学依据和指导。
2,4-二硝基氯苯SDS_PI
Material Safety Data SheetSection 1 – Chemical Product and Company IdentificationbenzeneName: 1-Chloro-2,4-dinitroMSDSSynonyms: 2,4-DinitrochlorobenzeneCompany Identification: Shanghai PI Chemicals Ltd.Room 6-306, Building 21341 Pudong South RoadPudong New Area, Shanghai 200212, ChinaNumber: 86-21-51389368TelephoneFax Number:86-21-51389367Number: 86-21-51389369EmergencySection 2 – Product InformationCatalog Number: PI-31357CAS #: 97-00-7Purity: 98.0%EINECS# 202-551-4Section 3 – Physical and Chemical PropertiesAppearance: Yellow crystalline powderodorOdor: CharacteristicMolecular Formula: C6H3ClN2O4Molecular Weight: 202.55Freezing/Melting Point: 50-54o CPoint: 315o C (760mmHg)BoilingFlash Point: 186o CRefractive Index (nD20): NotavailableavailableDensity: NotavailableDecomposition Temperature: NotSolubility:Insoluble in water; soluble in hot alcohol, ether, benzene Section 4 – Hazards IdentificationEye: Causes eye irritation.Skin: Causes skin irritation. Harmful if absorbed through the skin.Ingestion: May cause irritation of the digestive tract. Toxic if swallowed.Inhalation:Harmful if inhaled. Causes respiratory tract irritation.Section 5 – First Aid MeasuresEye: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.Skin: Get medical aid. Flush skin with plenty of water and soap for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops and persists. Ingestion: Get medical aid immediately. Wash mouth out with water.Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.Section 6 – Stability and ReactivityavailableStability: NotChemicalMaterials to avoid: Strong oxidizing agents,strong bases.materials.Conditions to Avoid: IncompatibleHazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbondioxide.occur.Hazardous Polymerization: WillnotSection 7 – Handling and StorageHandling:Avoid breathing dust, vapor, mist, or gas. Keep container tightly closed. Avoid contact with skin and eyes. Wash thoroughly after handling. Mechanical exhaust required.Storage:Store in a cool, dry place. Store in a tightly closed container.Section 8 – Personal ProtectionEyes:Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure.Clothing: Wear appropriate protective clothing to prevent skin exposure.Respirators:Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limitsare exceeded or if irritation or other symptoms are experienced.Section 9 – Fire and Explosion Hazard DataGeneral Information: As in any fire, wear a self-contained breathing apparatus, MSHA/NIOSH (approved or equivalent) and protective clothing to prevent contact with skin and eyes. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam.Section 10 – Accidental Release MeasuresGeneral Information: Use proper personal protective equipment as indicated in Section 8.Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.Section 11 – Toxicological InformationRTECS#:CAS# 97-00-7: CZ0525000LD50/LC50: RTECS:CAS# 97-00-7: Draize test, rabbit, eye: 50 ug/24H Severe;Draize test, rabbit, skin: 2 mg/24H Severe;Oral, rat: LD50 = 640 mg/kg;Skin, rabbit: LD50 = 130 mg/kgCarcinogenicity:1-Chloro-2,4-dinitro benzene- Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.Section 12 – Environmental informationEcotoxicity: Fish: Zebrafish: LC50: 0,71 mg/l; 96H; OECD 203Fish: Leuciscus idus: LC50: 0,75 mg/l; 96H; Statischer LabortestDaphnia: Daphnia: EC50: 1 mg/l; 24H; DIN 38412 Teil 11Other:Do not empty into drains. Non-biodegradable.log Pow: 2.17Section 13 – Disposal ConsiderationDissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state and local environmental regulations.Section 14 – Transport InformationIATA IMO RID/ADRShipping Name: TOXIC SOLID, ORGANIC, N.O.S.* TOXIC SOLID, ORGANIC, N.O.S. TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 6.1 6.1UN Number: 3411 3411 3411 Group: II II IIPackingSection 15 – Regulatory InformationEuropean/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:T NRisk Phrases:R 23/24/25 Toxic by inhalation, in contact with skin and if swallowed.R 33 Danger of cumulative effects.R 50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Safety Phrases:S 28A After contact with skin, wash immediately with plenty of waterS 36/37 Wear suitable gloves and eye/face protection.S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).S 60 This material and its container must be disposed of as hazardous waste WGK (Water Danger/Protection)CAS# 97-00-7: 2CanadaCAS# 97-00-7 is listed on Canada's DSL ListUS FederalTSCACAS# 97-00-7 is listed on the TSCA Inventory.Section 16 – Additional InformationMSDS Creation Date: 2/22/2007Update: OriginalThe above information is believed to be accurate and represents the best knowledge available to us currently. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall PI Chemicals, be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, even if PI Chemicals has been advised of the possibility of such damages.。
2,4-二硝基氯苯(4-氯-1,3-二硝基苯)化学品安全技术说明书MSDS
标识
中文名：
2,4-二硝基氯苯；4-氯-1,3-二硝基苯
英文名：
2,4-Dinitrochlorobenzene；4-Chloro-1,3-dinitrobenzene
分子式：
C6H3ClN2O4分子量：202.56
CAS号：
97-00-7RTECS号：CZ0525000
灭火方法：
雾状水、泡沫、二氧化碳、干粉、砂土。
包装与储运
危险性类别：
第6．1类毒害品危险货物包装标志：11包装类别：Ⅲ
储运注意事项：
储存于阴凉、通风仓间内。远离火种、热源。防止阳光直射。保持容器密封。应与氧化剂、食用化工原料分开存放。搬运时要轻装轻卸，防止包装及容器损坏。分装和搬运作业要注意个人防护。
毒性危害
接触限值：
中国MAC：1mg/m3[皮]；苏联MAC：0.05mg/m3[皮]；
美国TWA：未制定标准；美国STEL：未制定标准
侵入途径：
吸入食入经皮吸收
毒性：
LD50：1070mg/kg(大鼠经口)；130mg/kg(兔经皮)
健康危害：
可引起接触性皮炎，对机体有致敏作用。此外，还可引起其它过敏反应，如支气管哮喘等。有可能引起肝损害。偶有紫绀和全身中毒症状。
UN编号：
1577危险货物编号：61681IMDG规则页码：6103
理化性质
ቤተ መጻሕፍቲ ባይዱ外观与性状：
淡黄色或黄棕色针状结晶，有苦杏仁味。
主要用途：
合成染料、农药、医药的原料。
熔点(℃)：
53.4沸点：315
相对密度(水=1)：
1.69相对密度(空气=1):6.98
溶解性：
- 1、下载文档前请自行甄别文档内容的完整性，平台不提供额外的编辑、内容补充、找答案等附加服务。
- 2、"仅部分预览"的文档,不可在线预览部分如存在完整性等问题,可反馈申请退款(可完整预览的文档不适用该条件!)。
- 3、如文档侵犯您的权益，请联系客服反馈,我们会尽快为您处理(人工客服工作时间：9:00-18:30)。
SIGMA-ALDRICH Material Safety Data SheetVersion 4.1Revision Date 09/27/2010Print Date 12/07/20101. PRODUCT AND COMPANY IDENTIFICATIONProduct name : 1-Chloro-2,4-dinitrobenzeneProduct Number : 237329AldrichBrand :Sigma-AldrichCompany :3050 Spruce StreetSAINT LOUIS MO 63103USA+18003255832Telephone :+18003255052Fax :Emergency Phone # : (314) 776-65552. HAZARDS IDENTIFICATIONEmergency OverviewOSHA HazardsToxic by inhalation., Toxic by ingestion, Toxic by skin absorption, CorrosiveTarget OrgansPeripheral nervous system., Central nervous system, Blood, Liver, KidneyGHS Label elements, including precautionary statementsPictogramSignal word DangerHazard statement(s)H301 + H311 Toxic if swallowed or in contact with skin.H315 Causes skin irritation.H318 Causes serious eye damage.H331 Toxic if inhaled.H373 May cause damage to organs through prolonged or repeated exposure.H410 Very toxic to aquatic life with long lasting effects.Precautionary statement(s)P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.P273 Avoid release to the environment.P280 Wear protective gloves/ eye protection/ face protection.P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, ifpresent and easy to do. Continue rinsing.P311 Call a POISON CENTER or doctor/ physician.P501 Dispose of contents/ container to an approved waste disposal plant.HMIS ClassificationHealth hazard:3Flammability:1Physical hazards:0NFPA RatingHealth hazard:3Fire:1Reactivity Hazard:0Potential Health EffectsInhalation Toxic if inhaled. Material is extremely destructive to the tissue of the mucousmembranes and upper respiratory tract.Skin Toxic if absorbed through skin. Causes skin burns.Eyes Causes eye burns.Ingestion Toxic if swallowed.3. COMPOSITION/INFORMATION ON INGREDIENTS2,4-DinitrochlorobenzeneSynonyms :C6H3ClN2O4Formula :Molecular Weight : 202.55 g/molCAS-No. EC-No.Index-No. Concentration1-Chloro-2,4-dinitrobenzene97-00-7 202-551-4 - -4. FIRST AID MEASURESGeneral adviceConsult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.If inhaledIf breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.In case of skin contactWash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.In case of eye contactRinse thoroughly with plenty of water for at least 15 minutes and consult a physician.Continue rinsing eyes during transport to hospital.If swallowedNever give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.5. FIRE-FIGHTING MEASURESSuitable extinguishing mediaUse water spray, alcohol-resistant foam, dry chemical or carbon dioxide.Special protective equipment for fire-fightersWear self contained breathing apparatus for fire fighting if necessary.6. ACCIDENTAL RELEASE MEASURESPersonal precautionsWear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.Evacuate personnel to safe areas. Avoid breathing dust.Environmental precautionsPrevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.Methods and materials for containment and cleaning upPick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.7. HANDLING AND STORAGEPrecautions for safe handlingAvoid contact with skin and eyes. Avoid formation of dust and aerosols.Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.Conditions for safe storageKeep container tightly closed in a dry and well-ventilated place.8. EXPOSURE CONTROLS/PERSONAL PROTECTIONContains no substances with occupational exposure limit values.Personal protective equipmentRespiratory protectionWhere risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the solemeans of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).Hand protectionHandle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use inaccordance with applicable laws and good laboratory practices. Wash and dry hands.Eye protectionFace shield and safety glasses Use equipment for eye protection tested and approved under appropriategovernment standards such as NIOSH (US) or EN 166(EU).Skin and body protectionComplete suit protecting against chemicals, The type of protective equipment must be selected according to theconcentration and amount of the dangerous substance at the specific workplace.Hygiene measuresAvoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.9. PHYSICAL AND CHEMICAL PROPERTIESAppearanceForm crystallineColour yellowSafety datapH no data availableMelting point 48 - 50 °C (118 - 122 °F) - lit.Boiling point 315 °C (599 °F) - lit.Flash point 194 °C (381 °F) - closed cupIgnition temperature no data availableLower explosion limit 2 %(V)Upper explosion limit 22 %(V)Water solubility no data available10. STABILITY AND REACTIVITYChemical stabilityStable under recommended storage conditions.Conditions to avoidno data availableMaterials to avoidStrong bases, Strong oxidizing agents, HydrazineHazardous decomposition productsHazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas11. TOXICOLOGICAL INFORMATIONAcute toxicityLD50Oral - rat - 640 mg/kgRemarks: Blood:Methemoglobinemia-Carboxyhemoglobin.LD50Dermal - rabbit - 130 mg/kgRemarks: Skin irritationSkin corrosion/irritationSkin - rabbit - Severe skin irritation - 24 hSerious eye damage/eye irritationEyes - rabbit - Severe eye irritation - 24 hRespiratory or skin sensitizationno data availableGerm cell mutagenicityGenotoxicity in vitro - rat - LiverDNA damageGenotoxicity in vitro - Hamster - KidneyMorphological transformation.Genotoxicity in vivo - mouse - IntraperitonealDNA damageCarcinogenicityIARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH.NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.Reproductive toxicityno data availableSpecific target organ toxicity - single exposure (Globally Harmonized System)no data availableSpecific target organ toxicity - repeated exposure (Globally Harmonized System)no data availableAspiration hazardno data availablePotential health effectsInhalation Toxic if inhaled. Material is extremely destructive to the tissue of the mucous membranesand upper respiratory tract.Ingestion Toxic if swallowed.Skin Toxic if absorbed through skin. Causes skin burns.Eyes Causes eye burns.Signs and Symptoms of ExposureCough, Shortness of breath, Headache, Nausea, VomitingAdditional InformationRTECS: CZ052500012. ECOLOGICAL INFORMATIONToxicityToxicity to fish LC50 - Danio rerio (zebra fish) - 0.32 mg/l - 96.0 hEC50 - Daphnia magna (Water flea) - 0.49 mg/l - 48 hToxicity to daphniaand other aquaticinvertebrates.Persistence and degradabilityno data availableBioaccumulative potentialno data availableMobility in soilno data availablePBT and vPvB assessmentno data availableOther adverse effectsAn environmental hazard cannot be excluded in the event of unprofessional handling or disposal.Very toxic to aquatic life with long lasting effects.no data available13. DISPOSAL CONSIDERATIONSProductOffer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.Contaminated packagingDispose of as unused product.14. TRANSPORT INFORMATIONDOT (US)UN-Number:3441 Class: 6.1 Packing group: IIProper shipping name: Chlorodinitrobenzenes, solidMarine pollutant: NoPoison Inhalation Hazard: NoIMDGUN-Number: 3441 Class: 6.1 Packing group: II EMS-No: F-A, S-AProper shipping name: CHLORODINITROBENZENES, SOLIDMarine pollutant: Marine pollutantIATAUN-Number:3441 Class: 6.1 Packing group: IIProper shipping name: Chlorodinitrobenzenes, solid15. REGULATORY INFORMATIONOSHA HazardsToxic by inhalation., Toxic by ingestion, Toxic by skin absorption, CorrosiveDSL StatusAll components of this product are on the Canadian DSL list.SARA 302 ComponentsSARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 ComponentsSARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312HazardsAcute Health HazardMassachusetts Right To Know Components1-Chloro-2,4-dinitrobenzene CAS-No.97-00-7Revision Date1993-04-24Pennsylvania Right To Know Components1-Chloro-2,4-dinitrobenzene CAS-No.97-00-7Revision Date1993-04-24New Jersey Right To Know Components1-Chloro-2,4-dinitrobenzene CAS-No.97-00-7Revision Date1993-04-24California Prop. 65 ComponentsThis product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.16. OTHER INFORMATIONFurther informationCopyright 2010 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only.The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.。