肿瘤分子探针与成像_高明远

肿瘤分子探针与成像
高明远
中国科学院化学研究所，中关村北一街2号，北京 100190
*Email: gaomy@iccas.ac.cn

无机纳米颗粒以其独特的物理性质，在肿瘤成像应用领域展示出了广阔的应用前景。然而，纳米材料
的尺寸、形貌及表面修饰等诸多因素严重影响着纳米材料的物理性能及其体内分布与代谢途径。因此，发
展先进的化学合成方法，实现功能无机纳米材料的可控制备，对开发其生物体内应用至关重要。本报告将
详细介绍我们在纳米颗粒及其肿瘤成像应用方面所开展的相关研究工作及取得的最新研究进展[1-14]。

关键词：分子影像探针；肿瘤；磁共振；在体应用

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Tumor Probes and Imaging
Mingyuan Gao
Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190

Through either passive or active targeting, functional nanoparticles have shown great potentials in visualizing
tumors in vivo. In this presentation, we will present our recent results on tiny tumor imaging, tumor
micrometastasis imaging and the visualization of tumor microenvironment as well, apart from the synthesis and
surface functionalization of versatile inorganic nanoparticles.