SCI论文投稿-审稿人回信-实战讲解
难道我被退稿了?该如何解读期刊编辑的回信

难道我被退稿了?该如何解读期刊编辑的回信呕心沥血的杰作终于问世,带着一颗期待它茁壮成长的心,谨慎的投稿出去了!但接踵而来的却是审查者冗长的评论。
到底是毫无希望?或者是希望无穷?让人一头雾水。
在这篇文章中,我们以论文投稿后,常收到的回复信件,来解析期刊编辑对稿件的想法。
投稿的作者常遇到的挑战之一,就是解读编辑的回复信函。
有时候作者会以为被接受,但其实编辑只是用比较正面的语气来婉拒。
也有些时候,编辑在信件内建议出版的日期,这其实是个好的征兆,但是作者会因为信件中负面的词语而误解编辑的意思。
不幸的是,编辑的回信没有一定的格式;但我们还是可以藉由观察以下所列特定的语句,来学习了解编辑回复的涵意。
以下是常见的回复:※直接接受※接受,并需要小幅度修改※接受,并需要大幅度修改※拒绝,但有被接受的机会※拒绝,但没有被接受的机会※不经审查,直接拒绝直接接受:几乎不太可能会发生,因为评审的工作就是要提供作者一些建议。
所以,在我所访谈的多名高影响力科研人员当中,仅有两位有论文被直接接受的经验。
接受,并需要小幅度修改:这是我们所能预期的最好结果。
因此,当收到这样的回复时,应该要感到非常开心。
如果编辑提到一个确切出版的日期,或是要求作者做小辐度的改变,譬如增加参考文献、扩充结论、或提供相关名词定义等,都表示文章被接受。
编辑可能会提到这篇论文不需要第二次评审审查,直接由编辑做最后的确认即可;这种情况下,这篇论文就是「有条件地被接受(conditionally accepted)。
」接受,并需要大幅度修改:同样地,若收到这样的回复,表示论文被接受的机会从11%提升到50%。
有时候在这种情况下,如果我们很谨慎仔细的响应编辑,也就不需要第二次审查。
然而,比较常见的情况是会有第二次的评审审查,特别是当编辑已在信中指明。
编辑的信-实例一“Enclosed please find thereviewers’ report on your paper. One reviewer has minorrecommendations for revision, the other has fairly substantial recommendations.Although their reports are very positive about your paper, they also includehelpful suggestions for improving the paper, especially regarding ______.Because of the reviewers concerns, I cannot accept the paper in its presentform. I can offer, however, to send a revised version of the paper back to thesecond reviewer, should you wish to rework your argument substantially in linewith these reports and resubmit the paper to us. I am sorry to have to conveywhat I know will be disappointing news, but I do feel strongly that withcareful revision this essay could be accepted for publication in our journal.”编辑的信-实例二“I am sorry to have to return yourmanuscript because it falls outside our guidelines. However, we would like toinvite you to resubmit your article. In order to conform to our guidelines, youwould need to be formulate your article to clarify your thesis and re-situatethe piece within a more scholarly background.Thank you for considering ourjournal and we look forward to hearing from you.”拒绝,但可以重新投稿:这样的回复总是会附上评审的意见。
scit投稿各流程邮件回复模板

scit投稿各流程邮件回复模板尊敬的作者,非常感谢您对 SCIT 投稿的兴趣。
我们欢迎您的稿件,并为了方便您对投稿流程的了解,特为您准备了以下邮件回复模板。
致作者回执:尊敬的作者,感谢您选择 SCIT 作为您的投稿平台。
您的稿件已收到并进入审稿流程。
在此回复中,我们将向您介绍稿件审稿的各个阶段。
1. 投稿确认阶段:我们已收到您的投稿,并将在一个工作日内进行确认。
此阶段,我们会检查您的投稿是否符合 SCIT 投稿要求,并确认是否在指定领域内。
一旦投稿确认完成,我们将进入下一个阶段。
2. 审稿阶段:您的稿件已进入审稿流程,我们的编辑团队将对您的稿件进行初步评估。
评估方面包括但不限于题目与内容的相关性、创新性、实用性以及符合规范要求。
评审时间大约需要三到四周,您在此期间可以尽情期待我们的回复。
3. 审稿结果通知:在审稿阶段结束后,我们将向您发送审稿结果通知。
审稿结果可能包括接受、需要修改后再次审稿、拒绝等。
无论审稿结果如何,我们都会给出详细的评审意见和建议。
如果您的稿件被接受,我们将向您提供进一步的出版指导。
4. 出版准备阶段:如果您的稿件被接受,我们将进行出版准备工作。
这包括版权事宜、排版和校对工作。
版权事宜将由我们与您进行协商,以确保合同的签署和合作的顺利进行。
在排版和校对方面,我们的编辑团队将致力于提高您的文章质量,并确保其符合出版要求。
5. 出版通知:经过排版和校对工作后,您的稿件将正式出版。
我们将以电子邮件形式通知您出版的具体时间和日期,并为您提供文章的最终链接。
在此之后,您可以与您的同行、朋友和读者分享您的作品。
请注意,以上流程只是一般情况下的参考,实际流程可能会因具体情况而有所调整。
您在投稿期间,如果有任何疑问或需要进一步帮助,请随时与我们的编辑团队保持联系。
我们将竭诚为您提供支持和指导。
再次感谢您选择 SCIT,我们期待着您未来的贡献!谢谢和祝好!SCIT 投稿编辑部。
经验分享丨sci修改意见回复信

经验分享丨sci修改意见回复信
投稿至SCI期刊的论文大多会收到来自编辑初审、同行复审的修改意见,作者根据这些修改意见进行适当的修改。
修改完毕后最好附上一份书信,来表达对编辑和同行的感激,有些作者会对拒绝接受修改意见,那么就需要对拒绝修改的部分作出详细的理由说明。
收到编辑或是同行的修改意见,大多数情况下代表着编辑部对作者的论文感兴趣,此时要以一个谦虚的态度回应。
首先,要认真的回复编辑和同行的每一条建议,即便是拒绝修改,也要用温婉的语气充分说明拒修的理由。
例如:It is really true as Reviewer suggested that……这样的语句。
切莫遗漏编辑和同行的建议或是疑问,如此他们才会觉得受到了重视,得到了作者的尊重,自然会认为作者的态度认真,对论文的顺利通过很有很大的帮助。
其次,要谦虚礼貌,通篇使用礼貌用语表达对编辑和同行的敬畏之情,如有必要甚至在结尾可以使用客套话。
最重要的一点,接受和反驳建议都要有理有据,以科学、严谨的学术态度去对待他们,才能说服编辑和同行。
不过最好还是少一些反驳的语句,多多说明具体的修改具体在第几页什么部分,作者作出了什么样的修改,比起之前这样修改的原因和好处在哪里。
例如:Line 56, “……” was added;Line 154-155, the statements of “……” were corrected as “……”
回复修改意见,并不是一味的死板回复,需要讲究一定的技巧,才能大概率的获得编辑和同行评审更多有益于提升论文整体质量的意见。
sci回复审稿人意见模板

sci回复审稿人意见模板在科学研究中,稿件被审稿人退回需要进行修改,这时需要给审稿人回复并说明哪些地方进行了修改。
下面是SCI回复审稿人意见模板,供广大科研人员参考。
Dear Reviewer [审稿人的姓名],Thank you for your detailed and constructive comments on our manuscript entitled [文章标题]. We appreciate the time and effort you have put into reviewing our manuscript. We have carefully considered your comments, and have made the following revisions to the manuscript:[在此处列出对于审稿人提出的每个问题的修改意见及回复。
每个修改都应标注修改位置,例如:“Modified sentence in the second paragraph of the Introduction (line 14-15) to read a s follows:”(在引言部分第二段(第14-15行)更改句子如下:)]Once again, we would like to express our gratitude to you for your invaluable feedback and constructive comments, which have contributed significantly to the improvement of our manuscript. Wehope that the revised version of our manuscript meets with your approval.Sincerely yours,[你的名字]。
SCI审稿意见回复模板来了

SCI审稿意见回复模板来了首先大家需要明确一点,给编辑的叫cover letter,不是response letter ,我们先来看下大致格式。
•Thank you for giving us the opportunity to submit a revised draft of the manuscript “XXX” for publication in the Journal of YYY. We appreciate the time and effort that you and the reviewers dedicated to providing feedback on our manuscript and are grateful for the insightful comments on and valuable improvements to our paper. We have incorporated most of the suggestions made by the reviewers. Those changes are highlighted in the manuscript. Please see below, in blue, for a point-by-point response to the reviewers’ comments and concerns. All page numbers refer to the revised manuscript file with tracked changes.•Ac cording to the reviewer’s comments, we have revised the manuscript extensively. If there are any other modifications we could make, we would like very much to modify them and wereally appreciate your help. We hope that our manuscript could be considered for publication in your journal. Thank you very much for your help.•Thank you again for your positive comments on our manuscript. 杂志名 is an influential journal which aims to improve our understanding of cancer prevention / other. From all the papers published in your journal, readers have been learning a lot. Hopefully, we could have our article been considered of publication in your journal. Should there been any other corrections we could make, please feel free to contact us.•Thank you for your email dated xxxxxx enclosing the reviewers’ comments. We have carefully reviewed the comments and have revised the manuscript accordingly. Our responses are given in a point-by-point manner below. Changes to the manuscript are shown in underline / red / bold.•I hope that the changes I’ve made resolve all your concerns about the article. I’m more than happy to make any further changes that will improve the paper and/or facilitate successful publication.•Based on these comments and suggestions, we have made careful modifications to the original manuscript, and carefully proof-read the manuscript to minimize typographical and grammatical errors. We believe that the manuscript has been greatly improved and hope it has reached your magazine’s standard.回到正题,给审稿人的意见回信,叫做Response to Reviewers。
SCI论文审稿意见回复信修改范例模板

SCI论文审稿意见回复信修改范例模板
注:以下SCI论文审稿意见回复信修改范例的公开已得到作者同意,任何机构和个人不得在未经授权下转载
最新SCI论文审稿意见回复信修改范例1 - SCI论文英语润色服务:文章已发表在由 Elsevier 出版社旗下的SCI期刊《Vaccine》,标题为: Heparanase DNA vaccine delivered by electroporation induces humoral immunity and cytoimmunity in animal models (点击链接可查看全文)
最新SCI论文审稿意见回复信修改范例2 - SCI论文英语润色服务:文章已发表在SCI期刊《PLoS ONE》上,标题为: Simultaneous Detection and Identification of Enteric Viruses by
PCR-Mass Assay(点击链接可查看全文)
最新SCI论文审稿意见回复信修改范例3 - 同行资深专家修改润色服务:。
sci回复审稿人意见模板 -回复

sci回复审稿人意见模板-回复尊敬的审稿人,非常感谢您对我们的稿件进行审阅,并提供了宝贵的意见和建议。
根据您的反馈,我们对您提出的问题逐一进行了回答,以便进一步改善和完善我们的研究成果。
[问题1:请解释清楚为什么选择该研究主题。
]我们选择这个研究主题是因为它与当前科学社会的重要问题密切相关。
该主题基于对地球气候变化以及环境持续变化的探索。
目前,环境问题受到了人们越来越多的关注,其中气候变化是其中最紧迫且引人注目的问题之一。
我们希望通过研究来深入了解气候变化的根本原因以及与之相关的因素,以帮助我们更好地应对这个全球性的挑战。
[问题2:请更加详细地解释您所使用的研究方法并说明其可靠性。
]在我们的研究中,我们采用了XX方法来分析和解读数据。
这种方法已经被广泛用于类似的研究,并已被科学界公认为有效和可靠的分析工具。
我们通过仔细收集和整理相关数据,并运用适当的统计方法来得出结论。
此外,我们还进行了多次重复实验,以增加结果的可靠性和重复性。
在数据分析方面,我们采用了严格的统计学方法来检验结果的显著性和可信度。
总体来说,我们相信我们所使用的研究方法是可靠的,并能够有效地支持我们的研究结论。
[问题3:请进一步讨论您的研究结果对该领域的意义和影响。
]我们的研究结果对于该领域具有重要的意义和影响。
首先,我们的结果可以帮助科学家和政策制定者更好地了解气候变化的机理和动力学过程。
这种理解是制定有效的气候变化应对策略所必需的。
其次,我们的结果还可以为相关领域的进一步研究提供有价值的参考和基础。
我们的发现可能有助于揭示与气候变化相关的其他未知因素,并为深入研究提供新的思路和方向。
最后,我们的研究结果还对公众有重要意义,因为它可以提高人们对气候变化问题的认识,并推动人们采取积极的环保行动来减轻其影响。
[问题4:请回答如何应对审稿人提出的其他一些具体问题和建议。
]根据您提供的其他建议,我们将按照以下方式来应对:a. 针对您提出的统计方法方面的疑问,我们将进一步详细描述我们所采用的方法,并解释其适用性和优势。
SCI论文回复信怎么写? 辑文编译-4027

SCI论文回复信怎么写?投递出去的稿件不管期刊是否发表,都会收到编辑来信,根据编辑来信,我们便可得知,自己所投递的论文是否能发表,需要进行什么样的修改,更或者是改投什么样的期刊等。
而收到编辑的来信,对此作出回应是必然的事情。
特别是来信中附带着编辑和审稿人修改意见的来信,我们更要仔细的阅读,认真的回复,这样才有能提高自己的论文在SCI期刊中发表的几率。
那么我们应该怎么做呢?首先,绝对服从编辑的意见。
在审稿人给出各自的意见之后,编辑一般不会再提出自己的意见。
但是,编辑一旦提出某些意见,就意味着他认为这是文章里的重大缺陷,至少是不合他的口味。
这时,我们唯一能够做的只能是服从。
因为毕竟是人家掌握着生杀予夺的大权。
第二,永远不要跟审稿人争执。
跟审稿人起争执是非常不明智的一件事情。
审稿人意见如果正确那就不用说了,直接照办就是。
如果不正确的话,也大可不必在回复中冷嘲热讽,心平气和的说明白就是了。
大家都是青年人,血气方刚,被人拍了当然不爽,被人错拍了就更不爽了。
尤其是一些行业权威导师的学生,看到一审结果是major而不是minor本来就已经很不爽了,难得抓住审稿人的尾巴,恨不得拖出来打死。
举个例子,一个审稿人给的意见是增加两篇参考文献(估计也就是审稿人自己的文章),结果作者在回复中写到,making a reference is not charity!这种让审稿人没有颜面的措辞,便会引发审稿人的反感。
结果也就如大家所想的那样,这篇稿子理所当然的被拒了,虽然后来经编辑调解改成了major revision,但毕竟耽误的是作者自己的时间不是吗?第三,合理掌握修改和argue的分寸。
所谓修改就是对文章内容进行的修改和补充,所谓argue就是在回复信中对审稿人的答复。
这其中大有文章可做,中心思想就是容易改的照改,不容易改的或者不想改的跟审稿人argue。
对于语法、拼写错误、某些词汇的更换、对某些公式和图表做进一步解释等相对容易做到的修改,一定要一毫不差的根据审稿意见照做。
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如何发表SCI论文,丁香园很多战友都有谈到这个话题,再来说这个话题似乎是老生常谈。
所以,今天美捷登编辑剑走偏锋,将SCI论文发表中大家可能比拟感兴趣的一些小技巧整理出来,与大家分享。
一.SCI论文,并没有想像中的难写1.2.对于初写者,“抄写〞不可防止,妙在“抄写〞技巧。
同类性质的研究文章,撰写格式大同小异,所以,格式可以“照抄〞。
常用句型可灵活“抄〞用。
有些描述性、结论性的句子在读懂的情况下尽量用自己的语言表达和总结。
但千万不可照抄未读懂的原句,否那么,小者笑话百出,大者断送文章前程。
3.尽量使用你熟悉的词汇。
不要成心使用华美、少用或罕见词汇。
4.要舍得投入精力和时间。
5.文章写成后,一定要请导师、老板、共同作者或者同事审阅,有必要的话也可以请信誉度高的专业效劳公司〔比方美捷登〕把关,提高成功率。
二.如何投稿论文投向哪份杂志其实还是有学问的。
一般视课题的新颖及创造性、实验结果的完整及可靠性和论文写作质量而定。
如果你有足够的时间〔1年以上〕等,最好先投比你的目标杂志更高的杂志,哪怕是Lancet, NEJM,JAMA等都不妨一试。
这些杂志要么直接拒稿,要么送审后退稿〔及少数直接收稿〕。
前者一般不到一周完成,后者1-2提出里文章的“软肋〞的同时,往往会提出许多改良论文的良好建议。
如果你没有时间等,想让论文一次中的,又不愿“下嫁〞你的大作,那么就要费心选择了。
首先要正确判断你文章的内容及水平,在从资料库ISI Web of Knowledge :// isiwebofknowledge 查找相关专业的杂志。
再根据杂志刊名,杂志内容,IF三.如何选择审稿人许多杂志编辑希望你推荐3-4名审稿人,并很可能向你推荐的审稿人发审稿邀请。
所以推荐审稿人还是有学问的。
如果你推荐的审稿人太忙或者太“牛〞,他们根本不会理睬一般杂志的邀请,你的文章就可能不能及时找到审稿人。
其实杂志对审稿人的身份要求不是太高的,但审稿人必须是某专业的专家。
因此,许多在某专业发过论文的〔我指的是英文SCI〕的作者都会收到审稿邀请信。
因此,你在推荐审稿人时,不必太“挑剔〞。
建议:1. 推荐国外发过与你结果、结论相似文章的作者;2. 推荐你论文中曾引用论文的作者;3. 推荐你或你老板认识的同专业的教授、副教授。
在国际有些影响的国内的学者也可以,这些学者在国内不一定是“牛〞人,但深受国外学术界尊重。
靠,结果不能重复,还是设计本身有问题?这都是撤稿的理由。
但目前因体制原因国内有许多作者一稿多投,当文章被其中一份杂志接受后,作者就开始要求其他杂志撤稿。
此种一稿多投的行为为国外学者所不齿。
因为这样会浪费编辑和审稿人的大量时间。
五.如何请国外SCI杂志减免版面费用这里所说的几个问题,可能只是沧海一粟。
希望对大家有一点作用。
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六论文投出后的命运Content〕不适合所投刊物,编辑会比拟快地回信退稿。
如果格式(Format)有问题,编辑部也会即时要求重投〔Re-submission〕。
否那么,作者就进入等待期。
收到稿件后,编辑会挑选2-3名审稿人〔很可能是由您自己推荐的〕对论文进行评审。
论文评审大多是对作者采用匿名形式。
国外审稿人不是专职人员,也无评审费。
但他们是已经在本领域建立了地位的“牛人〞或者对本领域有相当研究但还不太知名的学者。
前者比拟忙碌,后者因考虑评审也可给自己带来声誉,所以会小心谨慎地进行评审。
因此两者完成评审可能都需要花较长时间。
等待2-33个月时间。
假设仍无消息,可以与编辑联系催促一下。
千万不要投稿一周就开始催促或过于频繁地催促,这样不仅不礼貌还会给编辑留下很不好的印象。
〔记住,也有比你更无耐心的编辑〕。
好的杂志一般都是按照杂志本身的时间规律去办事的。
-编辑在审稿过程中是仲裁和最后决策者。
一般本质上有四种结果:拒绝〔Rejection〕,修改后再投〔Re-submission〕, 修改〔大修〔Major revision〕或小修〔Minor revision),及接受(直接接受(Acceptance)或有条件接受(Conditional acceptance upon satisfactory revision))。
七如何对待编辑来信1. 拒绝〔Rejection〕国外刊物的拒稿率上下不等,5分以上的杂志拒稿率可高达80%,一般杂志拒稿率在302. 修改后再投〔Re-submission〕十几年前似乎没有修改后再投的情况。
现在也不是所有杂志有这个类别。
这种情况时有发生。
往往说明论文竞争力不够,甚至有缺陷。
通常需要补试验甚至送另一批建议,论文大多是会被接受的。
3. 修改〔大修〔Major revision〕或小修〔Minor revision)R1。
其实,许多杂志的“大修〞其修改程度不亚于上述的“修改后再投〞。
不易轻视。
同样,修改后的文章很可能会送原审稿人评审。
一般被接收的时机很大。
“小修〞的文章一般原那么上已被接受,但有少量地方需作者确认修改,故与有些杂志的“有条件接受〞差不多〔见下〕。
4. 接收〔Accepted with or without minor revision〕除少数杂志外,绝大多数杂志,尤其高质量的杂志,不会“直接接受(Accept as it is)〞第一次投稿的论文。
最好的情况是“有条件接受〔Accepted with or without minor revision〕〞,也就是只要作者同意做某方面的修稿或补充,论文即被接受。
但大多收论文经过第一次修后接收。
有时需要第二次修改。
一般修改两次还不能让审稿人满意,编辑往往会拒稿。
八,如何答复审稿人如何答复审稿人〔或写回复信Reply Letter〕是一门艺术,我们将会另辟专贴,详细举例介绍。
reputation,可以说拿信誉当生命。
当他们接到审稿要求时,如果很忙或不懂你的专业或领域,他们会decline“偏见“的心态去断定审稿人有〞偏见“1.所有问题必须逐条答复;2.3.满足不了的也不要回避,说明不能做的合理理由;4。
对于你不5. 审稿人推荐的文献一定要引用,并加以讨论。
九,论文被接受后的事项Transfer of Copy RightOpen access流行,收版面费的杂志多了,但至少半数以上的杂志仍然不收版面费。
pdf文本,电邮给索要者即可。
一般用个人信用卡(Credit Card)或单位的〔Purchase Order〕支付版面费。
很多杂志容许你选择论文发表后寄Invoice给你。
让你在论文发表后再付费。
信用卡在国内外已很普遍,非常方便、可靠。
所以,不必担忧资料“被盗〞的情况。
十,论文被发表后的事项论文一旦发表,不宜撤稿。
在许多人眼里,“撤稿〞几乎等同“学术不端行为〞。
所以,一稿多投或一稿多发亦涉及诚信问题,应在发表论文之前慎重考虑。
pdf文本。
如何回复审稿人提问,实例讲解:15 January 2021 〔第一讲〕给编辑的回复信论文题目:Pharmacokinetic and pharmacodynamic studies on the antivirus effects of A (一种中草药) against virus B 〔一种病毒〕所投杂志:Life Sciences投稿结果:这次大修后又经过一次小修,被接受发表编辑信内容〔注:有删节〕:Dear Mr. XXX,Your manuscript has been examined by the editors and qualified refereeMoon. We think the manuscript has merit but requires revision before we can accept it for publication in the Journal. Careful consideration must be given to the points raised in the reviewer comments, which are enclosed below.If you choose to submit a revision of your manuscript, please incorporate responses to the reviewer comments into the revised paper. A complete rebuttal with no manuscript alterations is usually considered inadequate and may result in lengthy re-review procedures.A letter detailing your revisions point-by-point must accompany the resubmission. You will be requested to upload this Response to Reviewers as a separate file in the Attach Files area.We ask that you resubmit your manuscript within 45 days. After this time, your file will be placed on inactive status and a further submission will be considered a new manuscript.You will see a menu item called Submission Needing Revision. You will find your submission record there.Yours sincerely,Joseph J. Bahl, PhDEditorLife SciencesFormat Suggestion: Please access the Guide to Authors at our website to check the format of your article. Pay particular attention to our References style.Reviewers' comments:Reviewer #1:XXXXX 〔略〕Reviewer #2:XXXXX 〔略〕Editors note and suggestions: 〔注:编辑的建议〕Title: Re-write the title to read more smoothly in contemporary English>>> Pharmacokinetic and pharmacodynamic studies of the antiviral effects of A against virus B.Abstract: Re-write the abstract to read more smoothly.A, an alkaloid isolated from C (注:一种中草药), was tested for antiviral activity against virus B. Both in vitro and in vivo assays along with serum pharmacological experiments showed A to have potent antiviral activity. The pharmacokinetic profile of A in Sprague/Dawley rat plasma after oral administration was measured by HPLC. Blood samples taken at selected time points were analyzed to study potential changes in antiviral pharmacodynamics as measured by infectivity of viruses. From the similarity of the serum concentration profiles and antiviral activity profiles it is concluded that A it self, rather than a metabolite, exerted the effect against the virus prior to bioinactivation. The need for effective clinical agents against virus B and these results suggest the possibility of benefit from further experiments with A.The authors should check to be sure that the terms blood samples, plasma and serum are always used appropriately throughout the abstract and text. Introduction: some sentences can be made less passive. example 1st paragraph >>>> A appears to be the most important alkaloid isolated from the plant, its structural formula is shown in Fig 1. ... While it produced a general inhibition of antibody production lymphocyte proliferation was stimulated (Xia and Wang, 1997). These pharmacological properties suggest a potential use in the treatment of viral myocarditis against virus B that could be studied in experiments in cell culture and animals.>>>The authors should check the entire manuscript for spelling errors (example given: in your text alkaloid is incorrectly spelled alkaloid)>>>The authors should read the guidelines to the authors and not include the first name of the authors being cited in the text. In the reference section the first name should be abbreviated as shown in the guideline to authors (thus the earlier text reference should be (Liu et al., 2003)and the remaining one should be (Chen et al., 2002)>>>>>The authors instead of directly answering the first complex question of reviewer #1 may include the three questions as future research aim in the discussion section.>>>>>>Rather than redrawing figure the authors may choose to amend the wording of the statistical analysis section to state that the result of tables are means +-SEMand for figures are +- SD.>>>>> reviewer #1 comment number 8 and reviewer # 2 comment 3 might be satisfied by inclusion of a representative photo of cells and heart showing CPE. Remember most readers of the journal have never seen what you are trying to describe.Because I think that you can deal with all of the points raised I am hoping to see a revised manuscript that you have carefully checked for errors. If you have questions or do not know how to respond to any of the points raised please contact me at bahl@ Joseph Bahl, PhD Editor 2 Life Sciences作者回复信原稿:Dear Dr. Bahl,I’m very appreciate 〔注:不适合作为给编辑回信的开始,同时有语法错误〕for your comments and suggestions.I 〔注:实际上是学生做的〕have conducted in vivo antivirus experiments again 〔注:要说明是应审稿人或编辑建议而作〕. Mice were sacrificed on 15 days and 30 days after infection. Death rate, heart weight to body weight ratio (HW/BW), virus titers and pathologic slices 〔注:用词错误〕were calculated〔注:用词不当〕. Production of mRNA of IL-10, IFN-γand TNF-αwere 〔注:语法错误〕measured by RT-PCR.I have revised this manuscript and especially paid much attention to your comments and suggestions. I would like to re-submit it to LIFE SCIENCE. Title of manuscript has been changed to “The antivirus effects of A against virus B and its pharmacokinetic behaviour in SD rats serum〞to make it more clear and smooth.Answers to Reviewers’questions were as follows: 〔注:可附在给编辑的回复信后〕Reviewer #1:XXXXXReviewer #2:XXXXXEditors note and suggestions:Title: Re-write the title to read more smoothly in contemporary EnglishAnswer: I have rewrite the title to “The antivirus effects of A against virus B and its pharmacokinetic behaviour in SD rats serum〞to make it more clear and smooth 〔注:多处语法错误〕.Abstract: Re-write the abstract to read more smoothly.Answer: I have revise the abstract carefully to make it more smooth and informative 〔注:语法错误〕.The authors should check to be sure that the terms blood samples, plasma and serum are always used appropriately throughout the abstract and text.Answer: I have paid attention to this question and it is clearer 〔注:不具体〕. Introduction:some sentences can be made less passive.Answer: I have revise the whole paper to make sentences less passive and obtained help of my colleague proficient in English 〔注:语法错误,句子不通顺〕.The authors should check the entire manuscript for spelling errorsAnswer: I’m very sorry to give you so much trouble for those spelling errors 〔注:不必抱歉,按建议修改即可〕. I have carefully corrected them.The authors should read the guidelines to the authors and not include the first name of the authors being cited in the text. In the reference section the first name should be abbreviated as shown in the guideline to authors (thus the earlier text reference should be (Liu et al., 2003) and the remaining one should be (Chen et al., 2002) Answer: I changed the style of references.Rather than redrawing figure the authors may choose to amend the wording of the statistical analysis section to state that the result of tables are means +-SEM and for figures are +- SD.Answer: 〔注:作者请编辑公司帮答复〕reviewer #1 comment number 8 and reviewer # 2 comment 3 might be satisfied by inclusion of a representative photo of cells and heart showing CPE. Remember: most readers of the journal have never seen what you are trying to describe.Answer: Thank you for your suggestions. I have supplemented pictures of cardiac pathologic slices in the paper (Fig2).I have to apologize for giving you so much trouble because of those misspelling and confusing statements 〔注:一般不是延误或人为失误,不必轻易抱歉,按建议修改即可〕. Your comments and suggestions really helped me a lot. I have put great efforts to this review. I wish it can be satisfactory.If there’s any information I can provide, please don’t hesitate to contact me. Thank you again for your time and patience. Look forward to hear 〔注:语法错误〕from you.Yours SincerelyXxxx Xxxx (通讯作者名)建议修改稿:Dear Dr. Bahl,Thanks you very much for your comments and suggestions.As suggested, we have conducted in vivo antivirus experiments. Mice were sacrificed on 15 days and 30 days after infection with virus B. Mortality, heart weight to body weight ratio (HW/BW), virus titers and pathologic scores were determined. In addition, mRNA expression of IL-10, IFN-γ and TNF-α were measured by RT-PCR.We have revised the manuscript, according to the comments and suggestions of reviewers and editor, and responded, point by point to, the comments as listed below. Since the paper has been revised significantly throughout the text, we feel it is better not to highlight the amendments in the revised manuscript 〔正常情况最好说明修改处〕.The revised manuscript has been edited and proofread by a medical editing company in Hong Kong.I would like to re-submit this revised manuscript to Life Sciences, and hope it is acceptable for publication in the journal.Looking forward to hearing from you soon.With kindest regards,Yours SincerelyXxxx Xxxx (通讯作者名)Replies to Reviewers and EditorFirst of all, we thank both reviewers and editor for their positive and constructive comments and suggestions.Replies to Reviewer #1:Xxxxx 〔略〕Replies to Reviewer #2:Xxxxx 〔略〕Replies to the Editors note and suggestions:Title: Re-write the title to read more smoothly in contmeporary EnglishAnswer: I have rewrite the title to “The antivirus effects of Sophoridine against Coxsackievirus B3 and its pharmacokinetics in rats〞to make it more clear and read more smoothly.Abstract: Re-write the abstract to read more smoothly.Answer: I have rewritten the abstract to make it more informative and read more smoothly.The authors should check to be sure that the terms blood samples, plasma and serum are always used appropriately throughout the abstract and text.Answer: I have paid attention to this issue, and they are now used appropriately throughout the abstract and text in the revised manuscript.Introduction:some sentences can be made less passive.Answer: I have revised the whole paper to make sentences less passive with the help of the editing company.The authors should check the entire manuscript for spelling errorsAnswer: This has been done by us as well as the editing company.The authors should read the guidelines to the authors and not include the first name of the authors being cited in the text. In the reference section the first name should be abbreviated as shown in the guideline to authors (thus the earlier text reference should be (Liu et al., 2003) and the remaining one should be (Chen et al., 2002) Answer: I have changed the style of references according to the journal.Rather than redrawing figure the authors may choose to ament the wording of the statistical analysis section to state that the result of tables aremeans +-SEM and for figures are +- SD.Answer: SD has been used throughout the text, and shown in the Figs. 3 and 4 in the revised manuscript.reviewer #1 comment number 8 and reviewer # 2 comment 3 might be satified by inclusion of a representative photo of cells and heart showing CPE. Remember: most readers of the journal have never seen what you are trying to describe.Answer: Thank you very much for the suggestion. I have added pictures of cardiac pathologic changes in the revised manuscript (Fig. 2).31 January 2021 〔第二讲〕给审稿人的回复信论文题目:Clinical implications of XXXX (一种病理指标) in X cancer所投杂志:BMC Cancer.结果:这次大修后被接受发表〔同时编辑在接受信中提出课题是否得到伦理委员会同意的问题。