英语ppt克隆

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英语克隆

英语克隆
ቤተ መጻሕፍቲ ባይዱ
There are people who are on the up-side of cloning
Humanity is plagued with many moral issues each day. With recent announcement that a research facility in England had successfully cloned a sheep, many more questions arose. The overall question is , "To clone or not to clone?" Many groups worldwide, doctors, politicians, religious people, have been battling with this question. Many doctors believe cloning is an advancement to help save more people's lives. Although specific organs or rare blood types have yet to be cloned and actually made available to the general medical community. Think about it: if someone desperately needed a liver transplant because they drank too much alcohol, with the aid of cloning technology, doctors would be able to clone that person's liver cells and produce a healthy, genetically matched liver, thus saving that patient's life. Cloning could revolutionize the medical industry! While many doctors are on the up-side of cloning, many politicians are on middle ground. Many see the medical need, but are reluctant. Most politicians want something for themselves for their endorsement either way on an important issue. Since cloning is not yet ready to be made accessible, by any means, to the general public, it is not yet a major issue to politicians. Since politicians make the laws worldwide, we will have to wait and see whether cloning is legal all out, only parts and specific uses legal, or all illegal.

高中生物课件:什么是克隆

高中生物课件:什么是克隆

切:限制性核酸内切酶酶切目的基因和载体。
接:目的片段与载体的连接 转:连接产物转入宿主细胞。 筛:筛选含有正确序列重组质粒的细菌。
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细胞克隆
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个体克隆
一株草莓依靠它沿地“爬走”的匍匐 茎,一年内就能长出数百株草莓苗
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富贵竹插枝即活
我国成功 繁殖克隆 兔体形要 比普通兔 大许多。
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克隆山羊 “阳阳”降 生在中国西 北农林科技 大学种羊场。
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中国第二 头克隆牛 “科科” 目前状况 一切正常。
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四、生物的克隆需要满足的条件 (以克隆羊多莉为例)
1、具有包含物种完整基因组的细胞核的活细胞。 2、能有效调控细胞和核发育的细胞质物质。 3、完成胚胎发育的必要的环境条件。
仙人掌每块落地就生根
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三、克隆技术发展的历史
阅读P19-20课文,总结克隆技术发展的历史
细胞克隆: 微生物克隆
分子克隆: DNA克隆 个体克隆: 克隆羊多莉
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补充:动物克隆技术的发展
克隆鱼
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美国研究 人员成功 克隆出世 界上第一 头骡子。
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克隆技术的发展
世界上首 例克隆马 “普罗梅 泰亚”在 意大利出 生。后面 是它的 “母亲兼 姐姐”。
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巴西 首次 培育 成功 克隆 牛。
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第 一 只 克 隆 猫 cc 诞 生

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《克隆与医学》PPT课件_OK

《克隆与医学》PPT课件_OK
生殖性克隆与治疗性克隆都是以细胞核移 植为基础,生殖性克隆的目的是要得到一个个 体,而治疗性克隆只需要得到早期胚胎,然后 从 早 期 胚 胎 中 分 离 得 到 ES 细 胞 , 再 将 ES 细 胞 分化为人们所需的细胞,进行细胞移植治疗或 用以构建组织工程化组织或器官。
克隆与12医学
2.生殖性克隆及治疗性克隆
Establish of ES cells
克隆与25医学
三、动物克隆技术的 应用前景
克隆与医学
26
1.动物克隆技术与医学
(1)克隆技术结合转基因技术制备动物生物 反应器
将转基因技术与克隆技术有机结合,以动 物体细胞为受体,将药用蛋白基因以DNA转染 的方式导入能进行传代培养的动物体细胞内, 再以这些携带目的基因的体细胞为核供体,进 行动物克隆。
(2)生殖性克隆及治疗性克隆的比较
生殖性克隆 最终产品 动物或人
目的 复制动物或人 需要时间 胚胎发育整个时间 移植子宫 需要 法律限制 对人禁止
治疗性克隆 可用于治疗的细胞、 组织或器官 修复受损的组织器官
短,几周
不需要
美、德等国反对;英、 中等国支持
克隆与13医学
二、动物克隆及治疗性 克隆技术的基本方法
3.克隆技术存在的问题
(1)理论和克隆技术不完善问题
克隆技术成功率低 体细胞克隆动物的成功率很低(1%~6%),主
要表现在流产率高,出生后对环境适应性差等。 这可能与供体核移入受体胞质后的重塑有关。供 体核发生去甲基化、去乙酰化等多种变化,在核 重塑过程中基因表达异常导致克隆效率降低。
克隆与38医学
克隆与6医学
1.克隆的一般概念
克隆的概念强调 以无性的方式进行增殖或繁殖 一个克隆中的每一成员其遗传构成完全相同

重组DNA技术ppt课件

重组DNA技术ppt课件

限制性核酸内切酶
切割DNA分子实 质是断开两个核 苷酸之间的磷酸 二酯键。
磷酸二酯键
DNA分子
限制酶的识别序列:
分类 Ⅰ、Ⅱ、Ⅲ (基因工程技术中常用Ⅱ型)
作用 与甲基化酶共同构成细菌的限制修
饰系统,限制外源DNA, 保护自身DNA。
Ⅱ类酶识别序列特点—— 回文结构(palindrome)
GGATCC CCTAGG
mRNA 反转录酶
cDNA 复制
双链cDNA 载体
重组DNA分子 受体菌cDNAAAAA逆转录酶AAAA TTTT
碱水解
TTTT
DNA聚合酶Ⅰ
SI核酸酶
目录
(二)克隆载体的选择和构建 (三)外源基因与载体的连接
目的基因
限制性内切酶
载体
限制性内切酶
重组体
T4 DNA连接酶 15ºC
载体自连
目的基因 自连
多肽链而特意设计的载体称为表达载体。
作为基因工程运载体的条件
①能够在宿主细胞中复制并稳定地保存。 ②具多种限制酶切点,以便与外源基因连接。 ③具有某些标记基因,便于进行筛选。 ④载体是安全的,不能对受体细胞有害。 ⑤载体DNA分子大小应合适,以便提取和在体外进行 操作。。
常用的载体:质粒
有标记基因的 存在,可用含 氨苄青霉素的 培养基鉴别
4. 聚合酶链反应(polymerase chain reaction, PCR)
组织或细胞染色体DNA 限制性内切酶
基因片断 克隆载体
重组DNA分子 受体菌
含重组分子的转化菌
* 从基因组DN带的所 有基因组DNA核苷酸序列不久即将完成。 但要揭示人类4万个基因功能的任务将更为艰巨。
人类基因组图谱的初步完成,不仅为全部基因 的定位建立了一个开放框架,而且为分离、鉴定人 类疾病相关基因提供了参照模板。

选修三 第二章 第一节 什么是克隆 课件ppt(15张)

选修三 第二章 第一节 什么是克隆 课件ppt(15张)

克隆
克隆(clone)为音译,实际就是无性繁殖。
无性繁殖:不经过两性生殖细胞,直接由母体形成个体。
繁殖速度: 快 特点
遗传性状: 与母本保持一致
任务2:构建克隆猴诞生的流程图
资料:
获得克隆猴的理论途径:选取3只母猴,将一只母猴的 卵细胞的细胞核去除;取第二只母猴的体细胞的核与去核 的卵细胞融合,形成重组细胞,并促使其分裂发育成早期 胚胎。胚胎发育到一定程度时再将它植入到第三只母猴的 子宫中,由它孕育并产生克隆羊。
分裂
抗体
未激活的
激活的
B淋巴细胞 B淋巴细胞
(效应B淋巴细胞)
杂交 瘤细胞
克隆
只要不通过两个分子、两个细胞或两个个体的结 合,只由一个模板分子、母细胞或母体直接形成新一 代分子、细胞或个体,就是无性繁殖,即克隆。
继“中中”和“华华”之后, 中国科学家又获得了几 只基因敲除的克隆猴。 它们是研究人类昼夜节 律现象的理想模型!
移植
母猴C 胚胎发育
克隆猴
个体水平上的克隆
不经过生殖细胞的结合(受精)而直接由体细胞
获得新个体。ຫໍສະໝຸດ 思考:若想从水母中获得荧光蛋白基因,并利用该 基因获得“绿色转基因克隆猴”,应该如何操作?
载体
获得 目的基因
荧光蛋白基因
导入
筛选 检测
重组DNA
猴体细胞
细胞核
荧光蛋白 转基因克隆猴
受体母猴
早期胚胎
重组细胞
去核卵细胞
【资料】日本科学家 将绿色荧光蛋白基因 导入卵细胞中,再让 其受精,最终生下来 的“绿光猴”。
分子水平上的克隆
在分子水平上,基因克隆是指某种目的基因的复 制、分离的过程。
体外 利用PCR技术扩增目的基因

北师大版高中英语选择性必修三Unit9Lesson1To Clone or not to Clone

北师大版高中英语选择性必修三Unit9Lesson1To Clone or not to Clone

Intensive Reading
1. What was the first cloned mammal? What happened to her?
It was a sheep named Dolly in 1996.
At first, Dolly grew normally. But later she developed an illness that is more normally found in much older animals. She lived for six and a half years, only half the life of the sheep from which she was cloned.
Summary
Complete the summary using the information in the article.
Natural cloning has taken place for generations. An example of this is identical 1 __tw__in_s___. A sheep called Dolly was the first mammal to be cloned 2 _a_r_t_if_i_c_ia_l_ly_. Since Dolly, more than 20 mammal 3 __sp_e_c_i_e_s___ have been cloned including camels and goats. In 2018, China announced that two monkeys had been cloned.
Intensive Reading 2. How has the science of cloning developed since the first cloned mammal?

高中英语Unit9HumanBiology课件北师大版选择性必修第三册

高中英语Unit9HumanBiology课件北师大版选择性必修第三册
10.He thinks that the work gives a correct ________,which future management efforts must take into account.
【答案】8.outbreak 9.classfication 10.baseline
形容词(adj. )&副词(adv. ) artificially, identical, forever, wholly, accurate, crucial, bound, rare, widespread, visible, actual, corresponding, symbolically 1.Her dress is almost ________ to mine. 2.There are ________ to be price increases next year. 【答案】1.identical 2.bound
8.He is optimistic that his government will be able to manage the ________ effectively.
9.Chinese garbage ________ policy has come into operation in several cities.
6.Physical activity is an important ________ in maintaining fitness.
7.It’s an interesting scientific ________,but of no practical use whatsoever.
【答案】6.factor 7.phenomenon

克隆英语

克隆英语

• 2. The identity of the clones are difficult to be determined. • The relationship between the clones and people be cloned cannot be adopted to the existing ethical relations.
利颖怡
李瑞银
蔡艳萍
卢银钿
邓海平
丘启成
冯春丽
What is cloning ?
• Cloning is the creation of cells
or whole animals using DNA from a single "parent", by passing the normal reproductive process. The clone has the same DNA to the parent.
Simplified Man's paternity Disrupted generational relation Individuals become isolated individuals Social network will become more complicated All of these will strongly threaten the traditional natural ethical relations、moral rules and political system.

Should Humans be cloned?
• Although the possibility of cloning humans has been the subject of speculation for much of the twentieth century, scientists and policy makers began to take the prospect seriously in the 1960s. • When asked whether scientists should be able to clone human, 85% said no, 11% said yes.
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Point of who objects the clone:
1、The clone technology is not now mature, the clone possibly has many congenital physiological deficiencies. 2、Clone's status recognized with difficulty that they with are unable by clone’s between relations to integrate the existing ethics system. 3、The humanity reproduces descendant's process no longer to need the both sexes fellowship, to the existing social relations, the family structure will have the huge impact which withstands with difficulty. 4、 The clone technology has the possibility to abuse, becomes the terrorist the tool.
own reproduction, will have clone's a series of disputes...
The twins were born at the same time ,they are natural clones
Do you know how many animals have been cloned?
Dolly was created!
DOLLY was born in 1997.
Macaque :Tetra,in 2000
In 2001,Cat appeared!

Horse was cloned!
Dog was cloned in ห้องสมุดไป่ตู้005.
And …
Cloning is the hope of human organ transplants
If the cloned embryo to adult culture, to obtain from him some "spare parts" - organs as transplants, but we how can a person (because human cloning are people too!) Any who made his organs? The cloning of human organs is a feasible way to resolve the scientists bred a headless human cloning for organ transplant, so that the supply of human organs factory, in order to solve the shortage of organs for transplant. However, this approach is in the end the feasibility acceptable basic principles of the international community need to match.
The generalized clone refers to every from an ancestor, passes through vegetative reproduction crowd of individuals.
But if its application in human
Conclusion:
In my opinion cloning have advantage and disadvantage,so we can’t only on the upside or on the down-side ,the key is to look at human beings how to use it.We should be good to the use of cloning technology to do more useful things for mankind.
Will the Cloned Einstein to understand the "theory of relativity" ??
clone is good or not??
Research advances over the past decade have told us that, with a little work, we humans can clone just about anything we want, from frogs to monkeys and probably even ourselves! So, we can clone things, but why would we want to? Let's look at some of the reasons people give to justify cloning.
5、From the biodiversity, the massive gene structure identical clone, possibly induces the new disease's widespread dissemination, is disadvantageous to humanity's survival. 6、 The clone counteracts in the human dignity, will cause to create one new slavery the condition. 7、The clone will give humanity's ethics system to bring “the sentimental black hole”, henceforth has cancelled the life sacred feeling, between people's sentiment greatly will possibly sell at a discount
Made by :
How much do you know about clone? What is clone?
The “克隆” is transliteration of clone, the scientist the process which reproduces the artificial heredity operation animal calls the clone, this biological technology is called the clone technology.
somepeople Supports the clone
The advangtages of clone:
Using the clone technology may in the rescue precious endangered animal, the expanded improved variety animal community, provides the sufficiency experiment animal, the advancement transgene animal research, to attack and capture the hereditary disease, the development high level new medicine, the production to be possible in internal organs official rank research which transplants for the human to play the role
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